Search results for " CRITICA"

showing 10 items of 2025 documents

Elective Cancer Surgery in COVID-19-Free Surgical Pathways during the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study

2020

PURPOSE As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19–free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a …

MaleCancer ResearchOutcome AssessmentInternational CooperationSettore MED/18 - CHIRURGIA GENERALESettore MED/19 - Chirurgia Plastica030230 surgeryAged; Aged 80 and over; COVID-19; Cohort Studies; Critical Care; Elective Surgical Procedures; Epidemics; Female; Humans; International Cooperation; Logistic Models; Male; Middle Aged; Neoplasms; Outcome Assessment Health Care; Postoperative Complications; SARS-CoV-2Cohort Studies0302 clinical medicineOperating theaterPostoperative Complicationscohort studiesNeoplasmsHealth caremiddle agedOutcome Assessment Health Care80 and overMedicineLungCancerCOVID-19/epidemiologyAged 80 and overOUTCOMESManchester Cancer Research CentrePulmonary ComplicationORIGINAL REPORTSMiddle AgedagedOncologyElective Surgical Procedures030220 oncology & carcinogenesisPneumonia & InfluenzaFemalePatient SafetyElective Surgical ProcedureLife Sciences & Biomedicine6.4 SurgeryCohort studyHumanmedicine.medical_specialtyelective surgical procedures/methodsLogistic ModelCritical CareAged; Aged; 80 and over; COVID-19; Cohort Studies; Critical Care; Elective Surgical Procedures; Epidemics; Female; Humans; International Cooperation; Logistic Models; Male; Middle Aged; Neoplasms; Outcome Assessment; Health Care; Postoperative Complications; SARS-CoV-2Clinical SciencesOncology and CarcinogenesisEpidemic[SDV.CAN]Life Sciences [q-bio]/Cancer-.cancer surgery ; COVID-19 ; SARS-CoV-2 pandemicepidemicsCOVIDSurg CollaborativeNOoutcome assessment health care/methods03 medical and health sciencesmaleSettore MED/28 - Malattie OdontostomatologicheClinical ResearchHumans1112 Oncology and CarcinogenesisOncology & CarcinogenesisElective surgeryEpidemicsElective Cancer Surgery in SARS-CoV-2 Elective Cancer Surgery in COVID-19 covid 19 sars-cov-2AgedScience & TechnologyElective Surgical Procedurebusiness.industrySARS-CoV-2PreventionResearchInstitutes_Networks_Beacons/mcrcEvaluation of treatments and therapeutic interventionsCOVID-191103 Clinical SciencesPneumoniaOdds ratiomedicine.diseaseHealth CarePneumoniaGood Health and Well Beingneoplasms/surgeryLogistic Modelscritical care/methodsEmergency medicinepostoperative complications/prevention & controlNeoplasmPostoperative ComplicationCohort Studiebusinessaged 80 and overSARS-CoV-2/physiologylogistic models
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Psychological experience of patients 3 months after a stay in the intensive care unit: A descriptive and qualitative study.

2015

Abstract Purpose The purpose was to describe psychological experiences of patients 3 months after a stay in the intensive care unit (ICU) using qualitative methods. Methods Twenty patients underwent clinical interview lasting 1 hour and completed the Impact of Event Scale—Revised and Hospital Anxiety and Depression questionnaires. All interviews were recorded and coded using thematic analysis. Results All patients (100%) reported that they could not remember their ICU stay; half reported confused memories (50%) or disorientation (50%). Negatives memories were also reported (20%-45%), namely, pain, distress, sleep difficulties, noise, fear, feeling of abandonment; 20% reported positive memor…

MaleCoping (psychology)medicine.medical_specialtymedia_common.quotation_subjectFamily supportEmotions[SHS.PSY]Humanities and Social Sciences/PsychologyAnxietyCritical Care and Intensive Care Medicinelaw.inventionStress Disorders Post-Traumatic03 medical and health sciences0302 clinical medicineOptimismlawSurveys and QuestionnairesAdaptation PsychologicalInterview PsychologicalmedicineHumans030212 general & internal medicineProspective StudiesPsychiatryComputingMilieux_MISCELLANEOUSQualitative Researchmedia_commonAgedbusiness.industryDepression030208 emergency & critical care medicineFearLength of StayMiddle AgedIntensive care unitPatient Discharge3. Good healthDistressIntensive Care UnitsMemory Short-TermFeelingAnxietyFemaleThematic analysismedicine.symptombusinessJournal of critical care
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Efficacy and safety of decompressive craniectomy with non-suture duraplasty in patients with traumatic brain injury.

2020

AbstractBackgroundDecompressive craniectomy is an important surgical treatment for patients with severe traumatic brain injury (TBI). Several reports have been published on the efficacy of non-watertight sutures in duraplasty performed in decompressive craniectomy. This study aims to evaluate the effectiveness of dura closure without sutures (non-suture duraplasty) in decompressive craniectomy for TBI.MethodsOne hundred and six patients were enrolled at a single trauma center between January 2017 and December 2018. We retrospectively collected the data and classified the patients into non-suture and suture duraplasty craniectomy groups. We compared the characteristics of patients and their …

MaleCritical Care and Emergency MedicineTraumatic Brain InjuryPhysiologymedicine.medical_treatmentBlood Loss SurgicalGlasgow Outcome ScaleNervous SystemVascular MedicineDiagnostic RadiologyNervous System Procedures0302 clinical medicineSuture (anatomy)AntibioticsBrain Injuries TraumaticMedicine and Health SciencesSurgical treatmentTomographyTrauma MedicineCerebrospinal FluidMultidisciplinaryAntimicrobialsRadiology and ImagingGlasgow Outcome ScaleTrauma centerQRDrugsMiddle AgedSevere Blood LossCranioplastySutureless Surgical ProceduresBody FluidsTreatment OutcomeMedicineFemaleDecompressive craniectomyAnatomyTraumatic InjuryResearch ArticleAdultDecompressive Craniectomymedicine.medical_specialtyImaging TechniquesTraumatic brain injuryScienceOperative TimeTrauma SurgerySurgical and Invasive Medical ProceduresNeuroimagingHemorrhageResearch and Analysis MethodsMicrobiologyCranioplasty03 medical and health sciencesSigns and SymptomsBlood lossDiagnostic MedicineMicrobial ControlmedicineHumansIn patientRetrospective StudiesPharmacologybusiness.industryBiology and Life Sciences030208 emergency & critical care medicinemedicine.diseaseComputed Axial TomographySurgeryDura MaterClinical MedicinebusinessNeurotraumaTrauma surgery030217 neurology & neurosurgeryNeurosciencePLoS ONE
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Relationships between depressive symptoms and self-reported unintentional injuries: the cross-sectional population–based FIN-D2D survey

2012

Background There is a lack of knowledge on the influence of different levels of physical activity (PA) on unintentional injuries among those with depressive symptoms (DS). The aim of this study was to evaluate the relationship between PA categories and unintentional injuries among participants with and without DS based on a cross-sectional population–based FIN-D2D survey conducted in 2007. Methods Out of 4500, 2682 participants (60%) aged 45–74 years attended in this study. The unintentional injuries over the past year were captured in a questionnaire. DS were determined with the Beck Depression Inventory (≥ 10 points) and PA with the International Physical Activity Questionnaire. The stati…

MaleCross-sectional studyPoison controlphysical activityInjuryLogistic regression0302 clinical medicineRisk FactorsNeurologia ja psykiatria - Neurology and psychiatry030212 general & internal medicineFunctional abilityDepression (differential diagnoses)Finlandinjurieseducation.field_of_studyDepressionlcsh:Public aspects of medicineDepressive symptomsMiddle AgeddepressionRegression AnalysisFemaletapaturmaResearch Articlemedicine.medical_specialtyPopulationMotor Activity03 medical and health sciencesdepressioliikunta-aktiivisuusInternal medicineInjury preventionmedicineHumanseducationBeck depression inventoryAgedbusiness.industryPhysical activityBeck Depression InventoryPublic Health Environmental and Occupational Health030208 emergency & critical care medicinelcsh:RA1-1270Health SurveysCross-Sectional StudiesAccidentsPhysical therapyWounds and InjuriesSelf ReportbusinessBMC Public Health
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Propofol sedation reduces diaphragm activity in spontaneously breathing patients: ultrasound assessment.

2017

BACKGROUND: The diaphragm is the most important respiratory muscle in humans, and the close relationship between inspired volume and diaphragmatic movement in normal subjects has led to investigations into diaphragmatic activity using ultrasound, during spontaneous breathing and sedative drug infusion. METHODS: A total of 36 consecutive patients undergoing diagnostic procedures under deep propofol sedation were studied. Ultrasound measurements included the following: diaphragmatic thickening end-inspiration (TEI) and endexpiration (TEE). Diaphragmatic thickening fraction (DTF) was calculated from [(TEI TEE) / TEE] at various time points (at T0 basal; at T1 during propofol infusion; at T2 aw…

MaleDeep sedation; Diaphragm; Propofol; Ultrasonography; Anesthesiology and Pain MedicineRespiratory rateSedationdeep sedation; diaphragm; propofol; ultrasonographyDiaphragmHypnotics and SedativeDiaphragmatic breathing03 medical and health sciences0302 clinical medicine030202 anesthesiologySettore MED/41 - ANESTESIOLOGIARespiratory muscleMedicineHumansHypnotics and SedativesProspective StudiesPropofolUltrasonographybusiness.industryRespirationUltrasound030208 emergency & critical care medicineMiddle AgedDiaphragm (structural system)Prospective StudieAnesthesiology and Pain MedicineAnesthesiaBreathingFemalemedicine.symptomDeep SedationbusinessPropofolmedicine.drugHumanMinerva anestesiologica
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Incidence, risk factors, clinical characteristics and outcomes of deep venous thrombosis in patients with COVID-19 attending the Emergency Department…

2021

Background and importance A higher incidence of venous thromboembolism [both pulmonary embolism and deep vein thrombosis (DVT)] in patients with coronavirus disease 2019 (COVID-19) has been described. But little is known about the true frequency of DVT in patients who attend emergency department (ED) and are diagnosed with COVID-19. Objective We investigated the incidence, risk factors, clinical characteristics and outcomes of DVT in patients with COVID-19 attending the ED before hospitalization. Methods We retrospectively reviewed all COVID patients diagnosed with DVT in 62 Spanish EDs (20% of Spanish EDs, case group) during the first 2 months of the COVID-19 outbreak. We compared DVT-COVI…

MaleDeep veinComorbidity030204 cardiovascular system & hematologyChest pain0302 clinical medicineRisk Factorsrisk factorsclinical characteristicsIncidenceIncidence (epidemiology)Age FactorsVenous ThromboembolismMiddle AgedPulmonary embolismVenous thrombosismedicine.anatomical_structureEmergency MedicineoutcomeFemalemedicine.symptomEmergency Service Hospitalsevere acute respiratory syndrome coronavirus 2Adultmedicine.medical_specialtyRisk Assessment03 medical and health sciencescoronavirus disease 2019Internal medicineThromboembolismmedicineHumanscardiovascular diseasesTromboembolismeAgedRetrospective Studiesdeep venous thrombosisbusiness.industryCOVID-19030208 emergency & critical care medicineRetrospective cohort studyOriginal ArticlesEmergency departmentOdds ratiomedicine.diseaseSpainCase-Control StudiesincidencePulmonary Embolismbusiness
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Medical pre-hospital management reduces mortality in severe blunt trauma: a prospective epidemiological study

2011

International audience; INTRODUCTION: Severe blunt trauma is a leading cause of premature death and handicap. However, the benefit for the patient of pre-hospital management by emergency physicians remains controversial because it may delay admission to hospital. This study aimed to compare the impact of medical pre-hospital management performed by SMUR (Service Mobile d'Urgences et de Réanimation) with non-medical pre-hospital management provided by fire brigades (non-SMUR) on 30-day mortality. METHODS: The FIRST (French Intensive care Recorded in Severe Trauma) study is a multicenter cohort study on consecutive patients with severe blunt trauma requiring admission to university hospital i…

MaleEmergency Medical ServicesTime FactorsMESH : AgedMESH : Prospective StudiesPoison controlCritical Care and Intensive Care Medicine0302 clinical medicineInjury Severity ScorePatient AdmissionEmergency medical services[ SHS.INFO ] Humanities and Social Sciences/Library and information sciences030212 general & internal medicineHospital MortalityProspective StudiesProspective cohort studyMESH: Treatment OutcomeMESH: AgedMESH: Middle AgedMortality rate[ SDV.SPEE ] Life Sciences [q-bio]/Santé publique et épidémiologieMESH : Patient AdmissionMESH : AdultMiddle Aged3. Good healthMESH : Wounds and InjuriesIntensive Care UnitsTreatment OutcomeBlunt traumaMESH: Young AdultBlunt traumaMESH: Emergency Medical ServicesInjury Severity ScoreMESH : Injury Severity ScoreFranceMESH: FirefightersMESH : Intensive Care UnitsCohort studyMESH : Time FactorsAdultmedicine.medical_specialtyAdolescentMESH : Male[SHS.INFO]Humanities and Social Sciences/Library and information sciencesMESH: Injury Severity ScoreMESH : Young AdultMESH : Treatment Outcome[SHS.INFO] Humanities and Social Sciences/Library and information sciencesMESH : Hospital Mortality03 medical and health sciencesYoung AdultIntensive careMESH : AdolescentmedicineHumansMESH : Emergency Medical ServicesMESH : Middle AgedMESH: Hospital MortalityIntensive care medicineMESH : FranceAgedMESH: AdolescentMESH: Humansbusiness.industryMESH: Patient AdmissionResearchMESH : HumansMESH: Time Factors030208 emergency & critical care medicineMESH: AdultMESH: MaleMESH: Prospective StudiesMESH: France[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologieMESH: Wounds and InjuriesFirefightersEmergency medicineWounds and InjuriesMESH: Intensive Care Units[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologieMESH : FirefightersbusinessCritical Care
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Involuntary ambulatory triage during the COVID-19 pandemic – A neurosurgical perspective

2020

BackgroundThe coronavirus disease 2019 (COVID-19) pandemic poses an unprecedented challenge to health-care systems around the world. As approximately one-third of the world´s population is living under "lockdown" conditions, medical resources are being reallocated and hospital admissions are limited to emergencies. We examined the decision-making impact of these actions and their effects on access to hospital treatment in patients with neurosurgical conditions.MethodsThis retrospective cohort study analyzes hospital admissions of two major neurosurgical services in Germany during the nationwide lockdown period (March 16th to April 16th, 2020). Spinal or cranial conditions requiring immediat…

MaleEuropean PeopleCritical Care and Emergency MedicinePulmonologyEpidemiologyGerman PeopleNeurosurgical ProceduresGeographical locationsNervous System ProceduresPatient Admission0302 clinical medicineGermanyPandemicEpidemiologyMedicine and Health SciencesEthnicitiesAged 80 and overeducation.field_of_studyMultidisciplinaryQRMiddle AgedHospitals3. Good healthEuropeElective Surgical Procedures030220 oncology & carcinogenesisQuarantineAmbulatoryMedicineFemaleNeurosurgeryMedical emergencyCoronavirus InfectionsEmergency Service HospitalElective Surgical ProcedureResearch ArticleAdultmedicine.medical_specialtyAdolescentSciencePneumonia ViralPopulationNeurosurgerySurgical and Invasive Medical ProceduresEpidemiology ; Neurosurgency ; COVID-19 ; Hospitals ; Surgical and invasive medical procedures ; Respiratory infections ; German people ; Germany ; Critical care and emergency medicineBetacoronavirusYoung Adult03 medical and health sciencesmedicineHumansEuropean UnioneducationPandemicsAgedRetrospective StudiesSARS-CoV-2business.industryCOVID-19Retrospective cohort studymedicine.diseaseTriageHealth CareHealth Care FacilitiesPeople and PlacesRespiratory InfectionsPopulation GroupingsEmergenciesTriagebusiness030217 neurology & neurosurgeryPLOS ONE
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High flow nasal therapy versus noninvasive ventilation as initial ventilatory strategy in COPD exacerbation: a multicenter non-inferiority randomized…

2020

Abstract Background The efficacy and safety of high flow nasal therapy (HFNT) in patients with acute hypercapnic exacerbation of chronic obstructive pulmonary disease (AECOPD) are unclear. Our aim was to evaluate the short-term effect of HFNT versus NIV in patients with mild-to-moderate AECOPD, with the hypothesis that HFNT is non-inferior to NIV on CO2 clearance after 2 h of treatment. Methods We performed a multicenter, non-inferiority randomized trial comparing HFNT and noninvasive ventilation (NIV) in nine centers in Italy. Patients were eligible if presented with mild-to-moderate AECOPD (arterial pH 7.25–7.35, PaCO2 ≥ 55 mmHg before ventilator support). Primary endpoint was the mean di…

MaleExacerbationEquivalence Trials as TopicCritical Care and Intensive Care MedicineAcute respiratory failurelaw.invention03 medical and health sciencesPulmonary Disease Chronic Obstructive0302 clinical medicineRandomized controlled triallawClinical endpointmedicineHumansCannulaAcute respiratory failure; Chronic obstructive pulmonary disease; High flow nasal cannula; High flow nasal therapy; Noninvasive ventilation030212 general & internal medicineHigh flow nasal therapyAgedCOPDbusiness.industryResearchhigh flow oxygen therapy high flow nasal cannula noninvasive ventilation COPD carbon dioxide acute respiratory failureChronic obstructive pulmonary diseaselcsh:Medical emergencies. Critical care. Intensive care. First aidOxygen Inhalation Therapylcsh:RC86-88.9Middle Agedmedicine.diseaseSymptom Flare UpConfidence intervalHigh flow nasal cannula030228 respiratory systemItalyAnesthesiaBreathingNoninvasive ventilationFemaleHigh flowbusinessNoninvasive ventilationHuman
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The palliative-supportive care unit in a comprehensive cancer center as crossroad for patients' oncological pathway

2016

Aim The aim of this study was to assess how an admission to an acute palliative-supportive care unit (APSCU), may influence the therapeutic trajectory of advanced cancer patients. Methods A consecutive sample of advanced cancer patients admitted to APCU was assessed. The following parameters were collected: patients demographics, including age, gender, primary diagnosis, marital status, and educational level, performance status and reasons for and kind of admission, data about care-givers, recent anticancer treatments, being on/off treatment or uncertain, the previous care setting, who proposed the admission to APSCU. Physical and psychological symptoms were evaluated at admission and at ti…

MaleGenetics and Molecular Biology (all)Palliative careCancer Treatmentlcsh:MedicineMedicine (all); Biochemistry Genetics and Molecular Biology (all); Agricultural and Biological Sciences (all)ToxicologyPathology and Laboratory MedicineBiochemistryCONSECUTIVE SAMPLE0302 clinical medicineNeoplasmsMedicine and Health SciencesMedicine030212 general & internal medicinelcsh:ScienceAnalgesicsMultidisciplinaryPharmaceuticsMedicine (all)Palliative CareHormonal TherapyDrugsHospitalsPatient DischargeHospitalizationOncologyCritical Pathway030220 oncology & carcinogenesisCritical PathwaysMarital statusHormonal therapyFemaleOff TreatmentEnd-of-life careResearch ArticleHumanmedicine.medical_specialtyPatientsAged; Analgesics; Female; Follow-Up Studies; Hospitalization; Humans; Male; Neoplasms; Patient Discharge; Patient Readmission; Cancer Care Facilities; Critical Pathways; Palliative Care; Medicine (all); Biochemistry Genetics and Molecular Biology (all); Agricultural and Biological Sciences (all)Cancer Care FacilitiesPatient ReadmissionFollow-Up Studie03 medical and health sciencesDrug TherapyPain ManagementHumansIntensive care medicineAgedPharmacologyBiochemistry Genetics and Molecular Biology (all)ToxicityPerformance statusCancer Care Facilitiebusiness.industrylcsh:RBiology and Life SciencesCancermedicine.diseaseHealth CareOpioidsAgricultural and Biological Sciences (all)Health Care FacilitiesEmergency medicineNeoplasmlcsh:QAnalgesicbusinessFollow-Up Studies
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