Search results for " ERA"
showing 10 items of 156 documents
Forecasting Hepatitis C liver disease burden on real-life data. Does the hidden iceberg matter to reach the elimination goals?
2018
Abstract Background & Aims Advances in direct‐acting antiviral treatment of HCV have reinvigorated public health initiatives aimed at identifying affected individuals. We evaluated the possible impact of only diagnosed and linked‐to‐care individuals on overall HCV burden estimates and identified a possible strategy to achieve the WHO targets by 2030. Methods Using a modelling approach grounded in Italian real‐life data of diagnosed and treated patients, different linkage‐to‐care scenarios were built to evaluate potential strategies in achieving the HCV elimination goals. Results Under the 40% linked‐to‐care scenario, viraemic burden would decline (60%); however, eligible patients to treat w…
The role of freshwater copepods in the environmental risk assessment of caffeine and propranolol mixtures in the surface water bodies of Spain
2019
In this study we aimed at assessing: (i) the environmental risk posed by mixtures of caffeine and propranolol to the freshwater ecosystems of Spain; (ii) the sensitivity of freshwater copepod species to the two compounds; (iii) if the toxicity of caffeine and propranolol to freshwater copepods contributes to the environmental risk posed by the two compounds in the freshwater bodies of Spain. The environmental risk was computed as the ratio of MECs (i.e. the measured environmental concentrations) to PNECs (i.e. the respective predicted no-effect concentrations). The effects of caffeine and propranolol on the freshwater cyclopoid Diacyclops crassicaudis crassicaudis were tested both individua…
Correction: Phylogeny of the Eurasian Wren Nannus troglodytes (Aves: Passeriformes: Troglodytidae) reveals deep and complex diversification patterns …
2020
The Mediterranean Basin represents a Global Biodiversity Hotspot where many organisms show high inter- and intraspecific differentiation. Extant phylogeographic patterns of terrestrial circum-Mediterranean faunas were mainly shaped through Pleistocene range shifts and range fragmentations due to retreat into different glacial refugia. Thus, several extant Mediterranean bird species have diversified by surviving glaciations in different hospitable refugia and subsequently expanded their distribution ranges during the Holocene. Such a scenario was also suggested for the Eurasian Wren (Nannus troglodytes) despite the lack of genetic data for most Mediterranean subspecies. Our phylogenetic mult…
Towards Big Data: Digitising Economic and Business History
2020
This chapter describes the experiences in computational and digital history of economic and business historians who for decades have been forerunners in digital history data gathering and computational analysis. It attempts to discuss the major developments within this area internationally and, in some specific cases, in Finland in the fields of digital economic and business history. It concentrates on a number of research projects that the authors have previously been involved in, as well as research outcomes by other economic and business historians within Finland and elsewhere. It is not claimed that the projects discussed are unique or ahead of their time in the field of economic and bu…
Some data on the transmission of the lives of saints between the Middle Ages and the modern era in the Crown of Aragon
2019
En l’edat mitjana les vides de sants eren models a seguir, exemples en els sermonaris i en els textos didacticodoctrinals. La popularitat d’aquestes vides es reflecteix en les arts plàstiques i visuals, en la literatura i en la cultura popular. A través de l’exemple de la transmissió escrita de tres vides de sants incloses en la traducció catalana de la Legenda aurea, presentem en aquest treball una aproximació a la manera en què es difonien aquelles vides, que circulaven de manera individual o integrades en compilacions i que podien oferir versions diferents en cada cas. La repercussió d’aquelles vides perviu en l’època moderna, que les recull en forma de composicions en vers, obres de tea…
Impacts of piscicide-induced fish removal on resource use and trophic diversity of lake invertebrates
2022
Chemical eradication of non-native species has become a widely used method to mitigate the potential negative im- pacts of altered competitive or predatory dynamics on biodiversity and natural ecosystem processes. However, the re- sponses of non-target species can vary from rapid full recovery to delayed or absent recolonization, and little is known about the potential shifts in resource use and trophic diversity of native species following chemical treatments. We used a before-after-control-impact approach to study the effects of rotenone piscicide treatment on abundance and tro- phic niche of benthic invertebrates in three untreated and three treated lakes in central Norway, the latter gr…
Normative Imperatives and Communal Influences : The Consistory's Role in Proposing Lutheran Clergy in the 18th-Century Russian Border Area
2017
Merit was strongly emphasized in the Privileges of the Clergy (in 1723) and legislative reforms, as well as in the formalization of election practices in connection with clerical appointments in the Kingdom of Sweden in the early 18th century. According to existing research, this resulted in a deepening difference between the standpoints of the laity and the ecclesiastical authorities. However, in studying the appointments of clergy in the Lutheran parishes in Russia’s western border area in the mid- and late 18th century, this article argues that the boundary between the opinions of the diocesan board (in this case the Consistory of Fredrikshamn) and those of the parishioners with regard t…
Adapting to supply chain 4.0: an explorative study of multinational companies
2019
The aim of this paper is to examine how multinational companies from five industries can adapt to what we call Supply Chain 4.0; the supply chain created as a result of the new digital era brought ...
Transmission Heterogeneity and Control Strategies for Infectious Disease Emergence
2007
Background The control of emergence and spread of infectious diseases depends critically on the details of the genetic makeup of pathogens and hosts, their immunological, behavioral and ecological traits, and the pattern of temporal and spatial contacts among the age/stage-classes of susceptible and infectious host individuals. Methods and Findings We show that failing to acknowledge the existence of heterogeneities in the transmission rate among age/stage-classes can make traditional eradication and control strategies ineffective, and in some cases, policies aimed at controlling pathogen emergence can even increase disease incidence in the host. When control strategies target for reduction…
Nei luoghi dell'accoglienza. Progetti per Lampedusa e Palermo
2014
Il libro raccoglie gli esiti della ricerca e della didattica dei Laboratori di Progettazione architettonica del terzo anno, svolti presso il corso di Laurea Magistrale in Architettura LM4 della Scuola Politecnica dell’Università degli Studi di Palermo, sul tema dell’accoglienza a Lampedusa e a Palermo. L’obiettivo è quello di presentare la composita esperienza di progetto e di ricerca prodotta intorno all’argomento e nello stesso tempo attivare un confronto sul paesaggio e sugli spazi urbani della città. Il libro cerca di sviluppare un percorso di ricognizione e di conoscenza attraverso l’elaborazione di progetti didattici in grado di produrre idee per la città e il territorio. The book con…