Search results for " Interferometry"
showing 10 items of 170 documents
An Experimental Toolbox for Structure‐Based Hit Discovery for P. aeruginosa FabF, a Promising Target for Antibiotics
2021
Abstract FabF (3‐oxoacyl‐[acyl‐carrier‐protein] synthase 2), which catalyses the rate limiting condensation reaction in the fatty acid synthesis II pathway, is an attractive target for new antibiotics. Here, we focus on FabF from P. aeruginosa (PaFabF) as antibiotics against this pathogen are urgently needed. To facilitate exploration of this target we have set up an experimental toolbox consisting of binding assays using bio‐layer interferometry (BLI) as well as saturation transfer difference (STD) and WaterLOGSY NMR in addition to robust conditions for structure determination. The suitability of the toolbox to support structure‐based design of FabF inhibitors was demonstrated through the …
Effects of maxillary protraction determined by laser metrology
1990
In this work we studied some of the main effects of the maxillary protraction orthopedic device. The initial dento-craniofacial reactions induced by maxillary protraction similar to that commonly employed in clinical practice are reported. The fringe counting holographic interferometry technique is used to measure displacements. The experiments were performed on a dried human skull; traction application points were situated over the permanent lateral incisors or over the first permanent molars. The results fundamentally reveal an anterior rotation of the dentomaxillary complex, more intense when traction is applied to the lateral incisors, as shown by a more marked extrusion of the molars i…
VLBI-resolution radio-map algorithms: Performance analysis of different levels of data-sharing on multi-socket, multi-core architectures
2012
a b s t r a c t A broad area in astronomy focuses on simulating extragalactic objects based on Very Long Baseline Interferometry (VLBI) radio-maps. Several algorithms in this scope simulate what would be the observed radio-maps if emitted from a predefined extragalactic object. This work analyzes the performance and scaling of this kind of algorithms on multi-socket, multi-core architectures. In particular, we evaluate a sharing approach, a privatizing approach and a hybrid approach on systems with complex memory hierarchy that includes shared Last Level Cache (LLC). In addition, we investigate which manual processes can be systematized and then automated in future works. The experiments sh…
Dual-polarization-pump CW laser operation in Nd3+:LiNbO3 channel waveguides fabricated by reverse proton exchange
2008
Abstract In this work, continuous-wave laser action at 1084.5 nm at room temperature in LiNbO 3 :Nd 3+ channel waveguides, fabricated by reverse proton exchange (RPE), is reported. The sample was pumped at λ = 808 nm in either σ or π-polarized configurations, TE- and TM-pumping schemes, being the laser emission π-polarized at all power levels. The laser characteristics, as function of the pumping scheme (TE or TM), have been obtained. In both cases, the laser emission was stable, without any reduction in the output power even under continuous pump operation at maximum power at room temperature, indicating high resistance to photorefractive damage.
Dual-Polarization Interferometry: A Novel Technique To Light up the Nanomolecular World
2015
[EN] The challenging lecture given in 1959 by physicist and Nobel Prize awarded R. P. Feynman: “There's plenty of room at the bottom” is considered to be the starting point for nanotechnology. With this peculiar title, Feynman encouraged researchers to explore beyond the atomic level and predicted exciting new phenomena that might revolutionize science and technology. Among these pioneering researchers are Eric Betzig, Stefan W. Hell and William E. Moerner, who have been awarded with the Nobel Prize in Chemistry 2014 for developing the super-resolved fluorescence microscopy. However, it is important to remark that the exploration of this amazing nanomolecular world began in the early 1980s …
Charged kaon femtoscopic correlations inppcollisions ats=7 TeV
2013
Correlations of two charged identical kaons (KchKch) are measured in pp collisions at root s = 7 TeV by the ALICE experiment at the Large Hadron Collider (LHC). One-dimensional (KKch)-K-ch correlation functions are constructed in three multiplicity and four transverse momentum ranges. The (KKch)-K-ch femtoscopic source parameters R and lambda are extracted. The (KKch)-K-ch correlations show a slight increase of femtoscopic radii with increasing multiplicity and a slight decrease of radii with increasing transverse momentum. These trends are similar to the ones observed for pi pi and K-s(0) K-s(0) correlations in pp and heavy-ion collisions. However at high multiplicities, there is an indica…
Measurement of correlations between pions from different W's in e+e- → W+W- events
1997
Correlations between pions from different W's in e(+)e(-) --> W+W- events are studied using data collected by the DELPHI detector at LEP running at a centre-of-mass energy of 172 GeV in 1996. At the present level of statistics, no enhancement of the correlation function above that expected from a pair of uncorrelated W's is observed at small values of the four-momentum difference of the pions. (C) 1997 Published by Elsevier Science B.V.
Dynamical masses of the low-mass stellar binary AB Doradus B
2015
Context. ABDoradus is the main system of the ABDoradus moving group. It is a quadruple system formed by two widely separated binaries of pre-main-sequence (PMS) stars: ABDor A/C and ABDor Ba/Bb. The pair ABDor A/C has been extensively studied and its dynamical masses have been determined with high precision, thus making of ABDor C a benchmark for calibrating PMS stellar models. If the orbit and dynamical masses of the pair ABDor Ba/Bb can be determined, they could not only play a similar role to that of ABDor C in calibrating PMS models, but would also help to better understand the dynamics of the whole ABDoradus system. Aims. We aim to determine the individual masses of the pair ABDor Ba/B…
Radio detection of the young binary HD 160934
2013
Precise determination of dynamical masses of pre-main-sequence (PMS) stars is essential to calibrate stellar evolution models that are widely used to derive theoretical masses of young low-mass objects. Binary stars in young, nearby loose associations are particularly good candidates for this calibration since all members share a common age. Interestingly, some of these young binaries present a persistent and compact radio emission, which makes them excellent targets for astrometric VLBI studies. We aim to monitor the orbital motion of the binary system HD 160934, a member of the AB Doradus moving group. We observed HD 160934 with the Very Large Array and the European VLBI Network at 8.4 an…
Holographic photoelasticity: Determination of absolute retardations by a single hologram
1976
In this paper, real-time holographic interferometry is applied to determine the absolute-retardation fringes in the photoelastic analysis of plane models. The method requires only one hologram recorded with the model unloaded. In the reconstruction process, the mcdel is loaded and the polarizers on the reference and object beams are rotated through the same angle. At the points of the model where the polarization direction is parallel to one of the principal stresses, only the corresponding family of absolute retardations is obtained. The technique is demonstrated experimentally using a deep beam centrally loaded.