Search results for " Seconda"

showing 10 items of 975 documents

Genetic and Biochemical Analysis of PadR-padC Promoter Interactions during the Phenolic Acid Stress Response in Bacillus subtilis 168

2011

ABSTRACT Bacillus subtilis 168 is resistant to phenolic acids by expression of an inducible enzyme, the phenolic acid decarboxylase (PadC), that decarboxylates these acids into less toxic vinyl derivatives. In the phenolic acid stress response (PASR), the repressor of padC , PadR, is inactivated by these acids. Inactivation of PadR is followed by a strong expression of padC . To elucidate the functional interaction between PadR and the padC promoter, we performed (i) footprinting assays to identify the region protected by PadR, (ii) electrophoretic mobility shift assays (EMSAs) with a modified padC promoter protected region to determine the interacting sequences, and (iii) random mutagenesi…

Leucine zipperMutantRepressorElectrophoretic Mobility Shift AssayGenetics and Molecular BiologyBacillus subtilisBiologyMicrobiologyProtein Structure Secondary03 medical and health scienceschemistry.chemical_compoundBacterial ProteinsStress PhysiologicalBacillus subtilis 168Hydroxybenzoates[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular BiologyPromoter Regions GeneticMolecular Biology030304 developmental biology2. Zero hungerchemistry.chemical_classification0303 health sciences030306 microbiologyMutagenesisPhenolic acidGene Expression Regulation Bacterialbiology.organism_classificationMolecular biologyFootprintingEnzymechemistryBiochemistryBacillus subtilisProtein Binding
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Characterization of the nucleation process of lysozyme at physiological pH: Primary but not sole process

2013

We report on a kinetic study of the heat-induced aggregation process of lysozyme at physiological pH. The time evolution of the aggregation extent and the conformational changes of the protein were followed by dynamic light scattering (DLS) and FTIR spectroscopy, respectively, whereas the morphology of the aggregates was observed by Atomic Force Microscopy (AFM). The conformational changes of the secondary and tertiary structures were simultaneous and distinct in time with respect to the formation of aggregates. Oligomer formation occurred through at least two different aggregation processes: a nucleation process and a homogeneous non-nucleative diffusion-controlled process. FTIR measuremen…

LightNucleation proceBiophysicsSupramolecular chemistryNucleationmacromolecular substancesProtein aggregationMicroscopy Atomic ForceBiochemistryOligomerProtein Structure Secondarychemistry.chemical_compoundDynamic light scatteringSpectroscopy Fourier Transform InfraredAnimalsScattering RadiationFourier transform infrared spectroscopyCircular DichroismOrganic ChemistryTemperaturetechnology industry and agricultureHydrogen-Ion ConcentrationProtein Structure TertiaryAmorphous solidFTIR spectroscopyCrystallographychemistryChemical engineeringDynamic light scatteringMuramidaseAFMProtein aggregationLysozymeChickensBiophysical Chemistry
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Yhteistyön mahdollisuudet – lukiokoulutukseen valmistava koulutus kielellistyvässä maailmassa

2018

Tassa tutkimuksessa selvitetaan sita, millaisia kasityksia rehtoreilla, opettajilla ja opiskelijoilla on vuorovaikutuksen mahdollistavasta toiminnasta eli yhteistyosta Lukiokoulutukseen valmistavan koulutuksen (LUVA) ja muun lukiotoiminnan valilla. Edellisen lisaksi tarkastellaan sita, ilmeneeko LUVA-koulutuksessa aineiston perusteella kielenoppimista tukevaa eri kielten limittaista kayttoa (engl.  translanguaging ).  Tutkimuksen teoreettinen tausta pohjautuu kielenoppimisen kayttopohjaiseen ajatteluun eli siihen, etta oppimisessa tarkeimpana nahdaan kielenkaytto ja vuorovaikutus. Taman artikkelin keskeinen teoreettinen kasite on  translanguaging , joka nahdaan vastakohtana yksikielisyyden …

Linguistics and LanguageFinnish as a second languagemultilingualismtranslanguagingcurriculumlcsh:Finnic. Baltic-Finniclcsh:PH91-98.5ta6121opetussuunnitelmamultilingual pedagogyCore curriculumLanguage and LinguisticsSyllabusvalmistava koulutusPedagogyta516monikielisyysCurriculumTranslanguagingSecondary levelpreparatory educationvalmistava koululukiosuomi toisena kielenäcurriculaLanguage acquisitionyksikielisyysmonolingual normpedagogiikkamonolingualismyksikielisyyden normigeneral upper secondary schoolsNorm (social)General Upper Secondary EducationPsychologyopetussuunnitelmatLähivõrdlusi. Lähivertailuja
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Defending either a personal or an assigned standpoint

2018

Abstract This study clarifies whether a specific type of role play supports upper secondary school students’ collaborative argumentation. Data consist of 12 dyadic face-to-face and 12 chat debates. Data analysis focused on the quality of students’ argumentation. Comparisons were made between students who defended standpoints at variance with their personal opinions on the topics, between the two study modes and topics, and by gender. When the students defended a standpoint differing from their personal opinion, the male students engaged in counterargumentation more often than the female students. When, in turn, the students defended their personal standpoint, they produced both counterargum…

Linguistics and Languagecomputer chatmedia_common.quotation_subjectcollaborative learningtoisen asteen koulutus050105 experimental psychologyLanguage and LinguisticsArgumentation theoryFace-to-faceargumentationComputingMilieux_COMPUTERSANDEDUCATIONMathematics educationta5160501 psychology and cognitive sciencesQuality (business)verkkojutteluyhteisöllinen oppiminenFemale studentsmedia_commonSecondary levelCommunication05 social sciences050301 educationCollaborative learningVariance (accounting)upper secondary schoolrole playargumentointiroolipelitPsychologystandpoint0503 educationJournal of Argumentation in Context
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Immigrant status, gender, and school burnout in Finnish lower secondary school students : A longitudinal study

2017

The aim of this longitudinal study among 9223 students from grade 7 and grade 9 (age 13–14 and 15–16) was to assess whether immigrant status and gender are associated with the level and change (slope) in school burnout among lower secondary school students in the Helsinki metropolitan area. Ninety-seven percent of the variation in school burnout was attributable to individual factors. Both the intercept (2.3, p < 0.001) and slope (0.5, p < 0.001) of school burnout were statistically significant. The slope showed increasing school burnout from grades 7–9. School burnout increased more in girls than in boys. Initially apparent higher school burnout among students who had immigrated to …

Longitudinal studySocial Psychologymedia_common.quotation_subjecthealth care facilities manpower and servicesImmigrationeducationkoulu (ilmiöt)Context (language use)pitkittäistutkimusBurnoutuupumusEducationsukupuolischool (phenomena)immigrant statusDevelopmental Neuroscienceupper comprehensive schoolHN Social history and conditions. Social problems. Social reformPedagogyexhaustionDevelopmental and Educational Psychology0501 psychology and cognitive sciencesStatistical analysis10. No inequalityLife-span and Life-course Studieslower secondary schoolta515media_commonLB1603 Secondary Education. High schools4. Education05 social sciencesMultilevel model050301 educationschool burnoutmaahanmuuttajatyläkouluPsychology0503 educationSocial Sciences (miscellaneous)psychological phenomena and processes050104 developmental & child psychologyClinical psychologyInternational Journal of Behavioral Development
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Lyapunov graphs for circle valued functions

2018

International audience; Conley index theory is used to obtain results for flows associated to circular Lyapunov functions defined on general compact smooth n-manifolds. This is done in terms of their underlying circular Lyapunov digraphs, which are generalizations of Morse digraphs, by extensively studying their combinatorics, invariants and realizability.

Lyapunov functionNovikov theoryPure mathematicsMathematics::Dynamical Systems010102 general mathematicsTEORIA DO ÍNDICEMorse code01 natural scienceslaw.inventionLyapunov graphs010101 applied mathematicssymbols.namesakeMorse functions[MATH.MATH-GN]Mathematics [math]/General Topology [math.GN]lawRealizabilitysymbolsGeometry and TopologyConley index theory0101 mathematicsMathematics::Symplectic GeometryGeneric circularMSC: primary 37B30 37B35 37D15 secondary 37E35MathematicsConley index
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How upper secondary students solve algebraic word problems in the area of mathematical modelling : A case study of one group of Norwegian students

2019

Masteroppgave matematikkdidaktikk MA500 - Universitetet i Agder 2019 For å imøtekomme nye utfordringer på skolen, i jobb og i livet, kan elever ha behov for åtilpasse og utvide den matematikken de kan. Dette krever at elever evner, i noen grad, åsette skolematematikken i forbindelse med hverdagslige kontekster og motsatt. Matema-tisk modellering er en av de hensiktsmessige mediene for å støtte sammenhengen mellomskolematematikken og virkeligheten. Forskning har vist at det er en sterk tilbøyelighet ipensumet mot matematisk modellering og at i stedet høynivå matematikk er ansett somviktig, mest på videregående nivå. Igjen, forskning viser at elever har større utfordringermed abstrakte (fakta…

MA500algebraic word problemmathematical modellingelever i videregåendeupper secondary studentsalgebraiske tekstoppgavermatematisk modelleringVDP::Samfunnsvitenskap: 200::Pedagogiske fag: 280::Fagdidaktikk: 283
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Relevansen av trigonometri : En studie i to deler på relevansen av trigonometri for elever på videregående skole

2017

Masteroppgave matematikkdidaktikk MA502 – Universitetet i Agder 2017 The topic of this master’s thesis is the relevance of mathematics, especially the relevance of trigonometry. Many students ask the question “why do I need to learn about this”. The aim of this study was to give the students an answer to this question. In the research literature, I found that this question has to do with relevance, and that relevance is a connection between people, an activity and future goals. In particular, one needs to question: relevance of what? relevance according to whom? relevance for whom? And relevance to what end? The empirical part of my research consisted of two studies. In Study 1 the purpose …

MA502UtdanningUpper secondaryRelevanceMatematikkVDP::Matematikk og Naturvitenskap: 400::Matematikk: 410TrigonometryRelevansTrigonometriVDP::Samfunnsvitenskap: 200::Pedagogiske fag: 280::Fagdidaktikk: 283MathematicsVideregåendeEducation
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The HOMFLY-PT polynomials of sublinks and the Yokonuma–Hecke algebras

2016

We describe completely the link invariants constructed using Markov traces on the Yokonuma-Hecke algebras in terms of the linking matrix and the HOMFLYPT polynomials of sublinks.

MSC: Primary 57M27: Invariants of knots and 3-manifolds Secondary 20C08: Hecke algebras and their representations 20F36: Braid groups; Artin groups 57M25: Knots and links in $S^3$Pure mathematicsMarkov chainGeneral Mathematics010102 general mathematicsYokonuma-Hecke algebrasGeometric Topology (math.GT)Linking numbers01 natural sciencesMathematics::Geometric TopologyMatrix (mathematics)Mathematics - Geometric TopologyMarkov tracesMathematics::Quantum Algebra[MATH.MATH-GT]Mathematics [math]/Geometric Topology [math.GT]0103 physical sciencesMathematics - Quantum AlgebraFOS: MathematicsQuantum Algebra (math.QA)010307 mathematical physics0101 mathematicsRepresentation Theory (math.RT)Link (knot theory)Mathematics - Representation TheoryMathematics
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Oxidation Enhances Human Serum Albumin Thermal Stability and Changes the Routes of Amyloid Fibril Formation

2014

Oxidative damages are linked to several aging-related diseases and are among the chemical pathways determining protein degradation. Specifically, interplay of oxidative stress and protein aggregation is recognized to have a link to the loss of cellular function in pathologies like Alzheimer's and Parkinson's diseases. Interaction between protein and reactive oxygen species may indeed induce small changes in protein structure and lead to the inhibition/modification of protein aggregation process, potentially determining the formation of species with different inherent toxicity. Understanding the temperate relationship between these events can be of utmost importance in unraveling the molecul…

Macromolecular AssembliesProtein Foldinglcsh:MedicineProtein aggregationBiochemistryPhysical Chemistry01 natural sciencesProtein Structure SecondaryProtein structurePathologylcsh:Sciencechemistry.chemical_classification0303 health sciencesMultidisciplinarybiologyProtein StabilityChemistryPhysicsNeurodegenerationTemperatureNeurodegenerative DiseasesHuman serum albuminChemistryNeurologyBiochemistryMedicineOxidation-ReductionMolecular PathologyResearch Articlemedicine.drugAmyloidBiophysicsSerum albuminProtein degradation010402 general chemistry03 medical and health sciencesDiagnostic MedicinemedicineHumansProtein InteractionsBiologySerum Albumin030304 developmental biologyAmyloid Fluorescence Oxidation Protein aggregation Spectoscopy Light Scattering Serum AlbuminReactive oxygen specieslcsh:RProteinsHydrogen Peroxidemedicine.diseaseProtein tertiary structure0104 chemical sciencesKineticsbiology.proteinlcsh:QProtein MultimerizationGeneral Pathology
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