Search results for " VAR"

showing 10 items of 5758 documents

Global diversity in the TAS2R38 bitter taste receptor: revisiting a classic evolutionary PROPosal

2016

AbstractThe ability to taste phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP) is a polymorphic trait mediated by the TAS2R38 bitter taste receptor gene. It has long been hypothesized that global genetic diversity at this locus evolved under pervasive pressures from balancing natural selection. However, recent high-resolution population genetic studies of TAS2Rs suggest that demographic events have played a critical role in the evolution of these genes. We here utilized the largest TAS2R38 database yet analyzed, consisting of 5,589 individuals from 105 populations, to examine natural selection, haplotype frequencies and linkage disequilibrium to estimate the effects of both selectio…

AFRICASELECTION0301 basic medicineLinkage disequilibriumPopulationLocus (genetics)Taste Genetics Evolutionary geneticsBiologyBalancing selectionLinkage DisequilibriumArticleReceptors G-Protein-CoupledEvolution Molecular03 medical and health sciences0302 clinical medicineDatabases GeneticGenetic variationLOCUSHumansPHENYLTHIOCARBAMIDESelection GeneticeducationPOPULATIONVEGETABLESGeneticsGenetic diversityeducation.field_of_studyHUMAN GENETIC DIVERSITY; SENSITIVITY; POPULATION; AFRICA; PTC; PHENYLTHIOCARBAMIDE; VEGETABLES; SELECTION; HUMANS; LOCUSNatural selectionMultidisciplinaryGenetic Variationphenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP)- TAS2R38 haplotypes-natural selectionPhenylthioureaCorrigendaSettore BIO/18 - GeneticaPTC030104 developmental biologyTAS2R38HaplotypesPropylthiouracilTasteHUMAN GENETIC DIVERSITYSENSITIVITY030217 neurology & neurosurgery
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Metabolic signatures across the full spectrum of non-alcoholic fatty liver disease.

2022

Funder: European Commission

ALTtype 2 diabetes mellitusROC receiving operator characteristicaspartate aminotransferaseHSDLDL low-density lipoproteinUHPLC ultrahigh-performance liquid chromatographyROCHCCNon-alcoholic steatohepatitisGCPCANASHGastroenterology2-HB 2-hydroxybutanoic acid; 3-HB 3-hydroxybutanoic acid; ALT alanine aminotransferase; AST aspartate aminotransferase; CE cholesterol ester; Cer ceramide; FFA free fatty acid; FLIP Fatty Liver Inhibition of Progression; Fibrosis; GC gas chromatography; HCC hepatocellular carcinoma; HSD honest significant difference; LC lipid cluster; LDL low-density lipoprotein; LM lipid and metabolite; LMC lipid metabolite and clinical variable; LPC lysophosphatidylcholine; Lipidomics; Mass spectrometry; Metabolomics; NAFL non-alcoholic fatty liver; NAFLD non-alcoholic fatty liver disease; NAS NASH activity score; NASH non-alcoholic steatohepatitis; NIDDK NASH-CRN National Institute of Digestive Diseases and Kidney NASH Clinical Research Network; NRR non-rejection rate; Non-alcoholic steatohepatitis; PC(O) ether PC; PC phosphatidylcholine; PCA principal component analysis; PE phosphatidylethanolamine; QTOFMS quadrupole-time-of-flight mass spectrometry; ROC receiving operator characteristic; SAF steatosis activity and fibrosis; SM sphingomyelin; T2DM type 2 diabetes mellitus; TG triacylglycerol; UHPLC ultrahigh-performance liquid chromatographySAFSAF steatosis activity and fibrosisLM lipid and metabolitehonest significant differenceHSD honest significant differenceTG triacylglycerolnon-rejection ratecholesterol esterPCPEGC gas chromatographyfree fatty acidFLIPNASH non-alcoholic steatohepatitisNIDDK NASH-CRN National Institute of Digestive Diseases and Kidney NASH Clinical Research NetworkBIOMARKERST2DMPE phosphatidylethanolamineLDLlipidNAFLDFFA free fatty acid2-HBMetabolomicsNAFL non-alcoholic fatty liverLMCphosphatidylcholineScience & TechnologySM sphingomyelinGastroenterology & HepatologyMass spectrometryactivitynutritional and metabolic diseasesT2DM type 2 diabetes mellitusACIDSreceiving operator characteristicdigestive system diseasesquadrupole-time-of-flight mass spectrometryLC lipid clusterlow-density lipoproteinNAS2-HB 2-hydroxybutanoic acidNAS NASH activity scoreQTOFMSether PCNRRSCORING SYSTEMprincipal component analysisgas chromatographyLC2-hydroxybutanoic acidPROGRESSIONAST aspartate aminotransferaseLMPC phosphatidylcholinePC(O)MARKERSUHPLCsteatosisTOOLImmunology and AllergyINSULIN-RESISTANCECerSMFatty Liver Inhibition of Progressionhepatocellular carcinoma2-HB 2-hydroxybutanoic acid NIDDK NASH-CRN National Institute of Digestive Diseases and Kidney NASH Clinical Research Network NRR non-rejection rate Non-alcoholic steatohepatitis PC(O) ether PC PC phosphatidylcholine PCA principal component analysis PE phosphatidylethanolamine QTOFMS quadrupole-time-of-flight mass spectrometry ROC receiving operator characteristic SAF steatosis activity and fibrosis SM T2DM type 2 diabetes mellitus TG triacylglycerol UHPLC ultrahigh-performance liquid chromatographyultrahigh-performance liquid chromatographyCELPC3-HBNAFLnon-alcoholic fatty liverTGtriacylglycerolNRR non-rejection rateLife Sciences & BiomedicineNAFLD non-alcoholic fatty liver diseaseFLIP Fatty Liver Inhibition of Progressionalanine aminotransferasemetaboliteCer ceramideCE cholesterol estersphingomyelinlysophosphatidylcholineand fibrosisALT alanine aminotransferaseInternal MedicineceramideNational Institute of Digestive Diseases and Kidney NASH Clinical Research NetworkAST3-HB 3-hydroxybutanoic acidQTOFMS quadrupole-time-of-flight mass spectrometryPCA principal component analysisLPC lysophosphatidylcholineHepatologynon-alcoholic fatty liver diseaseand clinical variablePC(O) ether PC3-hydroxybutanoic acidFibrosisNASH activity scoreNIDDK NASH-CRNlipid clusterlipid and metabolitephosphatidylethanolamineLipidomicsLMC lipid metabolite and clinical variableFFAHCC hepatocellular carcinomaJHEP reports : innovation in hepatology
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CAN ANCIENT DNA APPROACH DOCUMENT THE LOSS OF GENETIC DIVERSITY IN PYGMY CHIMPANZEES? A RESEARCH PROGRAM ON HISTORIC SAMPLES OF EUROPEAN PRIMATOLOGIC…

2009

ANCIENT DNA PYGMY CHIMPANZEE MUSEUM COLLECTIONS LOSS OF GENETIC VARIABILITYSettore BIO/08 - Antropologia
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Lauksaimniecības augsnes ķīmiskā sastāva izvērtējums pēc dažādu mēslošanas līdzekļu iestrādes

2015

Darbā analizēti augsnes un zālaugu paraugi uz vieglo stabilo izotopu attiecību masspektrometriju, sadarbojoties ar Latvijas Valsts mežzinātnes institūtu „Silava”. Paraugi iegūti no Viduslatvijas, Skrīveriem. Augsnes paraugiem noteikts augsnes pH, cinks, mangāns, varš, svins, niķelis, kadmijs un kobalta saturs. Iegūtie rezultāti tika izvērtēti.

AUGSNEĶĪMISKIE ELEMENTI AUGSNĒ CINKA MANGĀNA VARA SVINA NIĶEĻA KADMIJA UN KOBALTA NOTEIKŠANAVIEGLO STABILO IZOTOPU ATTIECĪBA.Ķīmija
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Is mental health literacy for depression associated with the intention toward preventive actions? A cross-sectional study among university students

2021

Objective Mental Health Literacy (MHL) might play an important role in preventing depression. This study assessed the MHL level for depression of university students and its association with intentions toward preventive actions against depression. Participants: University students (n = 315) were surveyed online. Methods: MHL level and group differences were analyzed using t-tests and one-way ANOVA. To investigate the relation between MHL and the intention for preventive actions against depression, correlation and regression analyses were performed. Results: The mean MHL level of the participants was reasonably high (42.65 of 75 points). MHL levels differed significantly between different gr…

AUSTRALIAN BACHELORCross-sectional studymental health literacymedia_common.quotation_subjectPublic Health Environmental and Occupational HealthPsychological interventionYOUNG-PEOPLEExplained variationSTIGMATIZING ATTITUDESPromotion (rank)intentionpreventive behaviorBELIEFSDepression preventionDISORDERS FINDINGSHELPAnalysis of varianceuniversity studentsPsychologyMental health literacyDepression (differential diagnoses)Depression preventionClinical psychologymedia_commonINTERVENTIONSJournal of American College Health
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An Arakelov inequality in characteristic p and upper bound of p-rank zero locus

2008

In this paper we show an Arakelov inequality for semi-stable families of algebraic curves of genus $g\geq 1$ over characteristic $p$ with nontrivial Kodaira-Spencer maps. We apply this inequality to obtain an upper bound of the number of algebraic curves of $p-$rank zero in a semi-stable family over characteristic $p$ with nontrivial Kodaira-Spencer map in terms of the genus of a general closed fiber, the genus of the base curve and the number of singular fibres. An extension of the above results to smooth families of Abelian varieties over $k$ with $W_2$-lifting assumption is also included.

Abelian varietyAlgebra and Number TheoryStable curveCombinatoricsAlgebraic cycleMathematics - Algebraic GeometryMathematics::Algebraic Geometry14D05 (Primary) 14G25 14H10 (Secondary)Algebraic surfaceFOS: MathematicsGenus fieldAlgebraic curveAbelian groupAlgebraic Geometry (math.AG)Singular point of an algebraic varietyMathematicsJournal of Number Theory
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Smooth structures on algebraic surfaces with cyclic fundamental group

1988

Abelian varietyAlgebraIntersection theorymedicine.medical_specialtyFundamental groupFunction field of an algebraic varietyGeneral MathematicsAlgebraic surfacemedicineSmooth structureAlgebraic geometry and analytic geometryMathematicsInventiones Mathematicae
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Automorphisms of hyperelliptic GAG-codes

2009

Abstract We determine the n –automorphism group of generalized algebraic-geometry codes associated with rational, elliptic and hyperelliptic function fields. Such group is, up to isomorphism, a subgroup of the automorphism group of the underlying function field.

Abelian varietyDiscrete mathematicsautomorphismsGroup (mathematics)Applied Mathematicsgeneralized algebraic geometry codes.Outer automorphism groupReductive groupAutomorphismTheoretical Computer ScienceCombinatoricsMathematics::Group Theorygeometric Goppa codeAlgebraic groupDiscrete Mathematics and Combinatoricsalgebraic function fieldsSettore MAT/03 - GeometriaIsomorphismfinite fieldsGeometric Goppa codesfinite fieldalgebraic function fieldHyperelliptic curvegeneralized algebraic-geometry codesMathematicsDiscrete Mathematics
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Non-archimedean hyperbolicity and applications

2018

Inspired by the work of Cherry, we introduce and study a new notion of Brody hyperbolicity for rigid analytic varieties over a non-archimedean field $K$ of characteristic zero. We use this notion of hyperbolicity to show the following algebraic statement: if a projective variety admits a non-constant morphism from an abelian variety, then so does any specialization of it. As an application of this result, we show that the moduli space of abelian varieties is $K$-analytically Brody hyperbolic in equal characteristic zero. These two results are predicted by the Green-Griffiths-Lang conjecture on hyperbolic varieties and its natural analogues for non-archimedean hyperbolicity. Finally, we use …

Abelian varietyPure mathematicsConjectureMathematics - Number TheoryApplied MathematicsGeneral Mathematics010102 general mathematics[MATH.MATH-AG] Mathematics [math]/Algebraic Geometry [math.AG]Field (mathematics)01 natural sciencesModuli spaceMathematics - Algebraic GeometryMorphism0103 physical sciencesUniformization theoremFOS: MathematicsNumber Theory (math.NT)[MATH.MATH-AG]Mathematics [math]/Algebraic Geometry [math.AG]010307 mathematical physics0101 mathematicsAbelian groupAlgebraic Geometry (math.AG)Projective varietyMathematicsJournal für die reine und angewandte Mathematik (Crelles Journal)
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Picard and the Italian Mathematicians: The History of Three Prix Bordin

2016

It is usually said that in the transition period between 19th and 20th centuries, French scholars (mainly Picard and Humbert) as well as Italian scholars (mainly Castelnuovo, Enriques and Severi) were interested in the study of algebraic surfaces, though using different methods.

Abelian varietyPure mathematicsHistoryAlgebraic surfaceAlgebraic functionAlgebraic geometryHumanitiesPeriod (music)
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