Search results for " consolidation."

L’organo straordinario di liquidazione e gli organi di governo del comune consustanziali alla sana gestione: un caso di studio

2022

Without wishing in any way to interfere in the substance of the legislation of local authorities in failure, this work concerns the possible contribution that the Extraordinary Liquidation Body (OSL) can make to the municipal government bodies on the rebalancing of a local authority. The starting point of the research project is the formalization of the declaration of bankruptcy approved by the City Council. Its evolutionary prospects are the measures launched in the context of extraordinary management entrusted to a liquidation body at the same time as the preparation of the hypothesis of permanently-rebalanced budget by the competence of the governing bodies in office. In parallel with th…

Is Sleep Disruption a Cause or Consequence of Alzheimer’s Disease? Reviewing Its Possible Role as a Biomarker

2020

In recent years, the idea that sleep is critical for cognitive processing has gained strength. Alzheimer’s disease (AD) is the most common form of dementia worldwide and presents a high prevalence of sleep disturbances. However, it is difficult to establish causal relations, since a vicious circle emerges between different aspects of the disease. Nowadays, we know that sleep is crucial to consolidate memory and to remove the excess of beta-amyloid and hyperphosphorilated tau accumulated in AD patients’ brains. In this review, we discuss how sleep disturbances often precede in years some pathological traits, as well as cognitive decline, in AD. We describe the relevance of sleep to memory co…

Lightweight Alloys Recycling and Processing through Innovative Friction Based Direct Technologies

In the last decades, the use of lightweight alloys has been spreading in almost any industrial field thanks to the relevant weight reduction allowed by the use of such materials. On the other hand, aluminium alloys are characterized by high-energy demands primary production cycles that are responsible for a relevant share of the global CO2 emissions. In order to limit and reverse such phenomenon, putting in place strategies to keep the material in the circle over multiple life cycles is mandatory and the concepts of circular economy, closed loop society and industrial symbiosis are progressively gathering more and more pace. Nevertheless, metal scraps are often mainly composed of chips resu…

2020

Learning to associate written letters with speech sounds is crucial for the initial phase of acquiring reading skills. However, little is known about the cortical reorganization for supporting letter-speech sound learning, particularly the brain dynamics during the learning of grapheme-phoneme associations. In the present study, we trained 30 Finnish participants (mean age: 24.33 years, SD: 3.50 years) to associate novel foreign letters with familiar Finnish speech sounds on two consecutive days (first day ​~ ​50 ​min; second day ​~ ​25 ​min), while neural activity was measured using magnetoencephalography (MEG). Two sets of audiovisual stimuli were used for the training in which the graphe…

L'intonaco Li Vigni nell'architettura del XX secolo a Palermo. Nuove conoscenze e applicazioni diagnostiche per la manutenzione

2013

Il saggio presenta lo studio degli intonaci formulati per imitare le pietre e i marmi naturali che si diffondono in Sicilia all’inizio del XX secolo ed evidenzia che le prime applicazioni e la diffusione delle nuove malte, anche nel resto dell’Italia, risentono delle sperimentazioni condotte in tutta l’Europa. Il contributo riassume i risultati di una rigorosa e capillare ricognizione tra i brevetti conservati presso l’Archivio Centrale dello Stato a Roma inerenti alle malte per il confezionamento dell’intonaco a “finta pietra”, ne analizza i contenuti in modo critico e pone in risalto i contatti culturali con le sperimentazioni dei materiali in atto nell’ambito dei grandi cantieri di resta…

Spatial learning and expression patterns of PP1 mRNA in mouse hippocampus.

2009

<i>Background:</i> Synaptic plasticity is believed to be the major cellular basis for learning and memory. Protein phosphorylation is a key process involved in changes in the efficacy of neurotransmission. In long-term changes synaptic plasticity is followed by structural plasticity and protein de novo synthesis. Such mechanisms are believed to build the basis of hippocampal learning and memory investigated in the Morris water maze (MWM) task. To examine the role of dephosphorylation during that model for spatial learning, we analyzed protein phosphatase 1 (PP1) expression in the hippocampus of mice at various stages of the task and in two groups with different learning abilitie…

Rapid nucleus-scale reorganization of chromatin in neurons enables transcriptional adaptation for memory consolidation

2020

AbstractThe interphase nucleus is functionally organized in active and repressed territories defining the transcriptional status of the cell. However, it remains poorly understood how the nuclear architecture of neurons adapts in response to behaviorally relevant stimuli that trigger fast alterations in gene expression patterns. Imaging of fluorescently tagged nucleosomes revealed that pharmacological manipulation of neuronal activity in vitro and auditory cued fear conditioning in vivo induce nucleus-scale restructuring of chromatin within minutes. Furthermore, the acquisition of auditory fear memory is impaired after infusion of a drug into auditory cortex which blocks chromatin reorganiz…

Hydrological Analysis of Loess Plateau Highland Control Schemes in Dongzhi Plateau

2020

Gully Consolidation and Highland Protection (GCHP) Project is a major soil and water conservation and land remediation project implemented in the Chinese Loess Plateau (CLP). As the connection between the mechanisms of erosion and practical applications for addressing it is not clear, the implementation of engineering measures to combat the problem has been insufficient to date. This study used field investigation and descriptive statistics, together with hydrological analysis modeling to gain an understanding of the impact of the Loess Plateau Highland Control Schemes on the evolution of the Dongzhi Plateau as the largest, most well-preserved, and the thickest loess deposit region in China…

Bio-inspired consolidants derived from crystalline nanocellulose for decayed wood

2018

Abstract Novel bio-inspired materials derived from crystalline nanocellulose (CNC) have been tested as wood consolidants. A suspension of CNC, produced by acid hydrolysis of cellulose and used as such or mixed with lignin and/or siloxane derivatives (PDMS), was applied on rotted wood samples of Norway spruce. X-Ray diffraction analysis on CNC powder showed high crystallinity index. Dynamic light scattering (DLS) measurement indicated a nearly uniform particle size distribution with an average hydrodynamic diameter for pure CNC smaller than that in the mixtures. Raman and FTIR spectroscopies suggested interactions between lignin, PDMS and CNC components. The storage modulus of wood samples, …

Outlining the Limits of Friction Stir Consolidation as Used as an Aluminum Alloys Recycling Approach

2021

Friction stir consolidation (FSC) is a solid-state process that recycles metal scraps economically and eco-friendly compared to the conventional melting method. The process parameters especially processing time and rotational speed, have a crucial role in achieving a sound disc during FSC. The current study answers the research question of how far these process parameters can be effective when the mass of chips to be recycled increases. In specific, an experimental setup was analyzed that was previously identified as challenging for recycling 20 g chips of aluminum alloy AA 2024-O. Rotational speed was set doubled, and processing time was increased up to 1.5 times of their initial values. T…