Search results for " injury"

showing 10 items of 1007 documents

Nerve injury in fractures of the condylar neck.

1977

Summary Although fractures of the condylar neck belong to the most frequent injuries of the jaws, and various nerves are found in close proximity to the temporomandibular joints, only little mention is made in the literature of neurological complications arising from accidents. We have therefore carried out a prospective study on nerve injuries in 237 fractures of the articular process in the period 1971–1975. We found two cases of post-traumatic Frey's syndrome, whereby the syndrome developed from a post-traumatic auriculotemporal neuralgia. We also found loss of function of auriculotemporal, buccal and facial nerves, and loss of taste sensation of the tongue in another case, caused by dam…

Malemedicine.medical_specialtyChordaFacial ParalysisSweating GustatoryAuriculotemporal nerveCondylestomatognathic systemTongueMandibular FracturesmedicineHumansProspective Studiesmedicine.cranial_nerveFacial Nerve Injuriesbiologybusiness.industryMandibular CondyleGeneral MedicineNerve injurymedicine.diseasebiology.organism_classificationFacial nerveSurgerymedicine.anatomical_structureNeuralgiaSurgeryFemaleBuccal nerveChorda Tympani Nervemedicine.symptombusinessJournal of maxillofacial surgery
researchProduct

Activity of superoxide dismutase copper/zinc type and prognosis in a cohort of patients with coronary artery disease.

2015

Aim: Superoxide dismutase (SOD) is important to control reactive oxygen species, but the relevance to human disease like coronary artery disease (CAD) and underlying ischemia/reperfusion injury is not clarified. Methods: For this study, 2239 patients with known CAD were prospectively followed with a median follow-up time period of 3.6 years and a maximum of 6.9 years. During follow-up cardiovascular death was reported in 103 cases. Results: SOD activity (log-transformed) was investigated as continuous and categorical variable, showing a significant influence on outcome in the fully adjusted model (p = 0.045). Conclusion: Increased SOD activity beyond the normal range in the human physiolog…

Malemedicine.medical_specialtyClinical BiochemistryIschemiaCoronary Artery Diseasemedicine.disease_causeGastroenterologyCoronary artery diseaseSuperoxide dismutaseInternal medicineDrug DiscoverymedicineHumansIn patientAgedchemistry.chemical_classificationReactive oxygen speciesbiologybusiness.industrySuperoxide DismutaseBiochemistry (medical)Middle Agedmedicine.diseaseSurgerychemistryCohortbiology.proteinFemalebusinessReperfusion injuryOxidative stressBiomarkersFollow-Up StudiesBiomarkers in medicine
researchProduct

Incidence, risk factors, and prognosis of gastrointestinal hemorrhage complicating acute renal failure.

2001

Incidence, risk factors, and prognosis of gastrointestinal hemorrhage complicating acute renal failure. Background Few prospective data are currently available on acute gastrointestinal hemorrhage (AGIH) as a complication of acute renal failure (ARF). The aim of the present study was to define incidence, sources, risk factors, and outcome of AGIH in patients with ARF. Methods We performed a prospective study on an inception cohort of 514 patients admitted for ARF to a nephrology intermediate care unit. Data on clinical risk factors for bleeding, frequency of occurrence of AGIH, length of hospital stay, and in-hospital mortality were collected. Independent predictors of AGIH were identified.…

Malemedicine.medical_specialtyCohort StudiesRisk FactorsInternal medicineIntensive careSeverity of illnesshistamine2-receptor antagonistsmedicineHumansHospital MortalityProspective StudiesRisk factorProspective cohort studybleeding complicationintensive careAgedbusiness.industryIncidenceAcute kidney injuryOdds ratioAcute Kidney InjuryLength of StayMiddle Agedmedicine.diseasePrognosiskidney failureSurgerycritical careItalyNephrologyhemostasisFemaleUpper gastrointestinal bleedingbusinessGastrointestinal HemorrhageKidney diseaseKidney international
researchProduct

Safety of meglumine gadoterate (Gd-DOTA)-enhanced MRI compared to unenhanced MRI in patients with chronic kidney disease (RESCUE study).

2012

To prospectively compare the renal safety of meglumine gadoterate (Gd-DOTA)-enhanced magnetic resonance imaging (MRI) to a control group (unenhanced MRI) in high-risk patients.Patients with chronic kidney disease (CKD) scheduled for MRI procedures were screened. The primary endpoint was the percentage of patients with an elevation of serum creatinine levels, measured 72 ± 24 h after the MRI procedure, by at least 25 % or 44.2 μmol/l (0.5 mg/dl) from baseline. A non-inferiority margin of the between-group difference was set at -15 % for statistical analysis of the primary endpoint. Main secondary endpoints were the variation in serum creatinine and eGFR values between baseline and 72 ± 24 h …

Malemedicine.medical_specialtyDrug-Related Side Effects and Adverse ReactionsContrast MediaNephrogenic Fibrosing DermopathyHeterocyclic CompoundsRisk FactorsOrganometallic CompoundsPrevalenceMedicineHumansRadiology Nuclear Medicine and imagingRenal Insufficiency ChronicneoplasmsNeuroradiologyAgedmedicine.diagnostic_testMegluminebusiness.industryAcute kidney injuryMagnetic resonance imagingInterventional radiologyGeneral MedicineAcute Kidney Injurymedicine.diseaseMagnetic Resonance ImagingEuropeTreatment OutcomeRadiology Nuclear Medicine and imagingNephrogenic systemic fibrosisAngiographyFemaleRadiologybusinessmedicine.drugKidney diseaseEuropean radiology
researchProduct

Prevention of pressure injuries in critically ill children: A preliminary evaluation

2020

Abstract Aims To evaluate a prevention strategy implemented to reduce incidence and severity of positioning related pressure injuries affecting pediatric patients in a pediatric critical care unit. Secondary objective was to evaluate compliance with preventive recommendations. Background The skin in infants or children has important physiological and anatomical differences compared with adults. Further, factors such as the immaturity of the skin and limited activity and mobility in pediatric critical care unit, along with the pressure exerted by medical devices, increases the risk of pressure ulcers in infants and children. The most effective preventive measures specific to this intensive c…

Malemedicine.medical_specialtyEvidence-based nursingAdolescentCritical IllnessPopulationDermatologyIntensive Care Units PediatricPediatricsPatient PositioningPathology and Forensic Medicinelaw.invention030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicineEvidence-based nursingRisk FactorslawPressure ulcer/ prevention & controlIntensive careHumansMedicineCumulative incidenceRisk factorChildeducationPressure UlcerPediatric intensive care uniteducation.field_of_studyPediatrics Intensive care unit030504 nursingbusiness.industryIncidenceIncidence (epidemiology)InfantSupport surfacesSkin CareIntensive care unitChild PreschoolEmergency medicineFemaleEnfermeríaPressure injury0305 other medical sciencebusinessJournal of Tissue Viability
researchProduct

Studies on the disposition, metabolism and hepatotoxicity of coumarin in the rat and Syrian hamster.

2002

The hepatotoxicity, metabolism and disposition of coumarin has been compared in male Sprague-Dawley rats and Syrian hamsters. The treatment of rats for 12, 24 and 42 weeks with diets containing 0.2 and 0.5% coumarin resulted in hepatotoxicity and increased relative liver weights. While levels of cytochrome P450 (CYP) and CYP-dependent enzymes were decreased, levels of reduced glutathione (GSH) and activities of UDP glucuronosyltransferase, gamma-glutamyltransferase and GSH S-transferase were increased. In contrast, coumarin produced few hepatic changes in the Syrian hamster. Following a single oral dose of 25 mg/kg [3-14C]coumarin, radioactivity was rapidly excreted by the rat and Syrian ha…

Malemedicine.medical_specialtyHamsterToxicologyRats Sprague-Dawleychemistry.chemical_compoundCytosolPharmacokineticsLiver Function TestsSpecies SpecificityOral administrationCoumarinsInternal medicineCricetinaemedicineToxicokineticsAnimalsheterocyclic compoundsTissue DistributionNutritionbiologyMesocricetusBody WeightCytochrome P450AnticoagulantsGeneral MedicineGlutathioneOrgan SizeCoumarinGlutathioneDietRatsEndocrinologychemistryLiverToxicitybiology.proteinChemical and Drug Induced Liver InjuryOxidation-ReductionFood ScienceFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association
researchProduct

Ball Impact Position in Recreational Male Padel Players: Implications for Training and Injury Management

2021

Racket sports such as padel are characterized by the repetition of unilateral gestures, which can lead to negative adaptations like asymmetries or overuse musculoskeletal injuries. The purpose of this study was to determine the differences in ball impact positions (i.e., forward or backward of the center of gravity) in nine stroke types in a sample of forty-eight recreational male padel players. The sample included 14,478 shots corresponding to 18 matches from six tournaments. Forty-eight male padel players were classified into two groups according to their level: trained (n = 24) and novice (n = 24). Type of stroke and ball impact position were registered using a computerized motion tracki…

Malemedicine.medical_specialtyHealth Toxicology and Mutagenesisracket sportsgame actionslcsh:MedicineArticlebiomechanics03 medical and health sciencesMotion0302 clinical medicinePhysical medicine and rehabilitationMatch movingPosition (vector)RacketmedicineHumans030212 general & internal medicineRecreationcomputer.programming_languageoveruse injurylcsh:RPublic Health Environmental and Occupational HealthTraining (meteorology)Racquet Sports030229 sport sciencesBiomechanical PhenomenaCenter of gravityBall (bearing)PsychologycomputerGestureInternational Journal of Environmental Research and Public Health
researchProduct

Comparison of Electromyographic Activity During Hip Extension Exercises Under Gravitational or Inertial Loading Conditions.

2021

Background: Hamstring injury prevention programs include strengthening, especially eccentric exercises using both gravitational and inertial loading. Inertial exercises are characterized by eccentric contractions of high intensity and velocity. This study aimed to analyze the muscular activation of the biceps femoris (BF), semitendinosus (ST), gluteus maximus (GM), and gracilis (GC) muscles during hip extension (HE) exercises performed under both gravitational and inertial loading conditions. Hypothesis: Inertial training would generate a greater activation of HE muscles than gravitational training. Study Design: Cross-sectional study. Level of Evidence: Level 4. Methods: Fifteen resistance…

Malemedicine.medical_specialtyInertial frame of referencePhysical Therapy Sports Therapy and RehabilitationHamstring MusclesGravitation03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationmedicineEccentricHumansOrthopedics and Sports MedicineMuscle SkeletalExerciseHamstring injurybusiness.industryElectromyographyResistance training030229 sport sciencesmedicine.diseaseCurrent ResearchExercise TherapyCross-Sectional StudiesHip extensionMuscle powerbusiness030217 neurology & neurosurgerySports health
researchProduct

Hypertonic saline solution and decompressive craniectomy for treatment of intracranial hypertension in pediatric severe traumatic brain injury.

2002

Experimental data 8 –11 and first clinical results in adults 12,13 suggest that hypertonic saline ( 1.0) may be highly effective in lowering ICP even when mannitol has lost its therapeutic potential after prolonged and repeated use. In children, only limited experience exists with the use of hypertonic saline solutions: a randomized prospective study in children with severe head injury compared the effects on ICP (increased to 15–20 mm Hg) of isotonic (0.9% NaCl) and hypertonic (3% NaCl) saline injections, demonstrating a beneficial effect of the hypertonic solution. 14 Another prospective randomized trial compared the effects of continuous infusion of either lactated Ringer’s solution (277…

Malemedicine.medical_specialtyIntracranial PressureTraumatic brain injurymedicine.medical_treatmentBrain damageCritical Care and Intensive Care MedicineDrug Administration ScheduleInjury Severity ScorePreoperative CaremedicineHumansChildInfusions IntravenousSalineOsmolePostoperative CareSaline Solution Hypertonicbusiness.industryHead injurySodiumGlasgow Coma ScaleAccidents Trafficmedicine.diseaseDecompression SurgicalHypertonic salineSurgeryAnesthesiaBrain InjuriesSurgeryDecompressive craniectomyAccidental Fallsmedicine.symptomIntracranial HypertensionbusinessTomography X-Ray ComputedCraniotomyThe Journal of trauma
researchProduct

Value and limits of computer-assisted tomography.

1980

Three years ago, at the VIIth International Congress of Radiology in Otorhinolaryngology, held in Copenhagen, the early impressive results of computer-assisted tomography (CAT) in otorhinolaryngology were presented. Since considerable technologic and diagnostic progress of CAT has taken place in the meantime, questions about the increase in CAT's value and the expansion of its limits are appropriate now. Computed and, in some cases, conventional tomograms of facial lesions are used in the discussion of these questions. There is no doubt of CAT's advance within the last few years; there are, however, limits of CAT to be emphasized: (a) coronal CAT might be uncomfortable (especially if the ga…

Malemedicine.medical_specialtyIntracranial tumorSkull NeoplasmsComputer assisted tomographyFacial BonesInternational congressMedicineCraniocerebral TraumaHumansNeck stiffnessAgedbusiness.industryHead injurymedicine.diseaseCervical spineOtorhinolaryngologyOtorhinolaryngologySpinal InjuriesCoronal planeFemaleRadiologyFacial NeoplasmsbusinessNuclear medicineTomography X-Ray ComputedHeadneck surgery
researchProduct