Search results for " medica"

Physical activity from adolescence to young adulthood: patterns of change, and their associations with activity domains and sedentary time

2021

Background Longitudinal studies demonstrate an average decline in physical activity (PA) from adolescence to young adulthood. However, while some subgroups of adolescents decrease activity, others increase or maintain high or low activity. Activity domains may differ between subgroups (exhibiting different PA patterns), and they offer valuable information for targeted health promotion. Hence, the aim of this study was to identify PA patterns from adolescence to young adulthood; also to explore the associations of (i) changes in PA domains and in sedentary time, (ii) sociodemographic factors, and (iii) self-rated health with diverging PA patterns. Methods The observational cohort study data …

Western Australian students' alcohol consumption and expenditure intentions for Schoolies.

2016

In Australia, the immediate post-school period (known as ‘Schoolies’) is associated with heavy drinking and high levels of alcohol-related harm. This study investigated students’ intended alcohol consumption during Schoolies to inform interventions to reduce alcohol-related harm among this group. An online survey was administered to students in their senior year of schooling. Included items related to intended daily alcohol consumption during Schoolies, amount of money intended to be spent on alcohol over the Schoolies period, and past drinking behaviour. On average, participants (n=187) anticipated that they would consume eight standard drinks per day, which is substantially higher than t…

Assessment of Knowledge, Attitudes, and Propensity towards HPV Vaccine of Young Adult Students in Italy

2020

Background: Human Papillomavirus (HPV) is a common sexually transmitted infection (STI), representing the main cause of genital warts and cervical cancer. This cross-sectional study evaluated knowledge and attitudes about HPV infection, related diseases, and prevention and propensity towards HPV vaccine among undergraduate students. Methods: An online and written survey about HPV and its prevention, targeted to young adults of both genders, was addressed to students attending health sciences and other schools at Universities of Genoa and Bari. Results: The overall median knowledge and attitude scores were 56.3% (25&ndash

Impact of using different levels of threshold-based artefact correction on the quantification of heart rate variability in three independent human co…

2020

Heart rate variability (HRV) is a non-invasive indicator of autonomic nervous system function. HRV recordings show artefacts due to technical and/or biological issues. The Kubios software is one of the most used software to process HRV recordings, offering different levels of threshold-based artefact correction (i.e., Kubios filters). The aim of the study was to analyze the impact of different Kubios filters on the quantification of HRV derived parameters from short-term recordings in three independent human cohorts. A total of 312 participants were included: 107 children with overweight/obesity (10.0 &plusmn

Mediating Effects of Global Negative Effect Expectancies on the Association between Problematic Cannabis Use and Social Anxiety

2017

The relationship between social anxiety and cannabis use among adolescents and young adults is a highly debated topic. In this cross-sectional study, we tested whether cannabis use expectancies mediated the association between social anxiety and cannabis use severity in a sample of 343 young adults (74.3% male) who used cannabis. They completed self-report measures for the screening of problematic cannabis use (Cannabis Use Problems Identification Test) and social anxiety symptoms (Social Interaction Anxiety Scale and Social Phobia Scale). A multiple mediation analysis was used to test whether marijuana effect expectancies mediate social anxiety effect on problematic cannabis use. Social an…

Staying inside : social withdrawal of the young, Finnish ‘Hikikomori’

2016

This article explores socially withdrawn young Finnish people on an Internet forum who identify with the Japanese hikikomori phenomenon. We aim to overcome the dualism between sociology and psychology found in earlier research by referring to Pierre Bourdieu, who provides insights into how individual choices are constructed in accordance with wider social settings. We focus on the individual level and everyday choices, but we suggest that psychological factors (anxiety, depression) can be seen as properties of social relations rather than as individual states of mind, as young adults have unequal access to valued resources. We scrutinise young people’s specific reasoning related to the soci…

Risk behavior of youth – social definition of risk

2020

Social defining of the risk behaviors is rooted in a diverse, multidimensional world of norms, values, rituals and discourses. Including social contexts of engaging in the risk behaviors and production of knowledge about them allowed us to go beyond standard cause-and-effect descriptions and examine these actions as an essential element of everyday practices and rituals of youth. The aim of this paper was to analyze the risk behaviors of youth in the framework of sociological categories of risk, reflexivity and interactional order. The paper is based on the results of the qualitative study conducted within the project “Problem Behaviors of Youth – Study in the Opole Region 2019–2020,” that …

Over-dispersion in Oral Health: The state of art of statistical methodology

2011

Analysis of molecular mechanisms and anti-tumoral effects of zoledronic acid in breast cancer cells

2012

Background: Zoledronic acid (ZOL) is the most potent nitrogen-containing bisphosphonate (N-BPs) that strongly binds to bone mineral and acts as a powerful inhibitor of bone resorption, already clinically available for the treatment of patients with osteolytic metastases. Recent data also suggest that ZOL, used in breast cancer, may provide more than just supportive care modifying the course of the disease, though the possible molecular mechanism of action is still unclear. Aims: Since breast cancer is one of the primary tumors with high propensity to metastasize to the bone, we investigated, for the first time, differential gene expression profile on MCF-7 breast cancer cells treated with l…

Modeling multipartite virus evolution: the genome formula facilitates rapid adaptation to heterogeneous environments

2020

Multipartite viruses have two or more genome segments, and package different segments into different particle types. Although multipartition is thought to have a cost for virus transmission, its benefits are not clear. Recent experimental work has shown that the equilibrium frequency of viral genome segments, the setpoint genome formula (SGF), can be unbalanced and host-species dependent. These observations have reinvigorated the hypothesis that changes in genome-segment frequencies can lead to changes in virus-gene expression that might be adaptive. Here we explore this hypothesis by developing models of bipartite virus infection, leading to a threefold contribution. First, we show that th…