Search results for " metal"
showing 10 items of 2159 documents
Catalisi da sali di Cu(II) nelle reazioni di trasposizione eterociclica mononucleare.
Reattività dei fenilidrazoni E e Z del 3-benzoil-5-fenil-1,2,4-ossadiazolo in presenza di sali di Cu(II)
Estudio sobre el estado de Memoria en pacientes con Trastorno Mental Grave y aplicación - comparación de dos Tratamientos en Metacognición y posibles…
2021
Resumen: El trastorno mental grave (TMG) se considera de etiología multicausal, de carácter severo y persistente de síntomas psicóticos y engloba varios trastornos de entre los cuales el más estudiado es la esquizofrenia que manifiesta un deterioro cognitivo con inicio en fase premórbida. Según los estudios no existe síntoma patognomónico que la diferencia de otros trastornos. Sin embargo se ha podido comprobar que los déficits cognitivos que más se repiten dentro del trastorno son alteraciones de las funciones ejecutivas como la atención, inhibición, organización y planificación en la memoria de trabajo verbal (MTV), originando un deterioro en el nivel funcional del paciente. Aunque se rep…
Pharmacologic Inhibition of ADAM10 Attenuates Brain Tissue Loss, Axonal Injury and Pro-inflammatory Gene Expression Following Traumatic Brain Injury …
2021
The α-secretase A disintegrin and metalloprotease 10 (ADAM10) regulates various physiological and pathophysiological processes. Despite its broad functional implications during development, plasticity, and disease, no pharmacological approaches to inhibit ADAM10 in acute brain injury have been reported. Here, we examined the effects of the ADAM10 inhibitor GI254023X on the neurological and histopathological outcome after experimental traumatic brain injury (TBI). C57BL/6N mice were subjected to the controlled cortical impact (CCI) model of TBI or sham procedure and received GI254023X or vehicle during the acute phase of injury (n = 40, 100 mg/kg, 25% DMSO, 0.1 M Na2CO3, intraperitoneal, 30 …
Different strategies to achieve Pb-tolerance by the two Trebouxia algae coexisting in the lichen Ramalina farinacea.
2012
Lichen thalli are permeable to airborne substances, including heavy metals, which are harmful to cell metabolism. Ramalina farinacea shows a moderate tolerance to Pb. This lichen comprises two Trebouxia phycobionts, provisionally referred to as TR1 and TR9, with distinct physiological responses to acute oxidative stress. Thus, there is a more severe decay in photosynthesis and photosynthetic pigments in TR1 than in TR9. Similarly, under oxidative stress, antioxidant enzymes and HSP70 protein decrease in TR1 but increase in TR9. Since Pb toxicity is associated with increased ROS formation, we hypothesized greater Pb tolerance in this phycobiont. Accordingly, the aim of the present study was …
Halogen‐Imparted Reactivity in Lithium Carbenoid Mediated Homologations of Imine Surrogates: Direct Assembly of bis‐Trifluoromethyl‐β‐Diketiminates a…
2020
The selective formal insertion (homologation) of a carbon unit bridging the two trifluoroacetamidoyl chlorides (TFAICs) units is reported. The tactic is levered on a highly chemoselective homologation-metalation-acyl nucleophilic substitution sequence which precisely enables to assemble novel trifluoromethylated β-diketiminates within a single synthetic operation. Unlike previous homologations conducted with LiCH2Cl furnishing aziridines, herein we exploit the unique capability of iodomethyllithium to act contemporaneously as a C1 source (homologating effect) and metalating agent. The mechanistic rationale grounded on experimental evidences supports the hypothesized proposal and, the struct…
Radical salts of TTF derivatives with the metal-metal bonded [Re2Cl8]2- anion
2008
Abstract Four new salts of the radical cations of TMTSF (tetramethyltetraselenafulvalene), TMTTF (tetramethyltetrathiafulvalene), BEDT-TTF (bisethylenedithiotetrathia-fulvalene) (ET) and o-Me2TTF (o-4,4′-dimethyltetrathiafulvalene) with the metal–metal bonded dianion [Re2Cl8]2− were synthesized, and their structures and physical properties investigated. The structures of these semiconducting salts feature one-dimensional stacking of the donor molecules interleaved with [Re2Cl8]2− anions and interstitial solvent molecules.
MMP-10/stromelysin-2 promotes invasion of head and neck cancer.
2011
BackgroundPeriostin, IFN-induced transmembrane protein 1 (IFITM1) and Wingless-type MMTV integration site family, member 5B (Wnt-5b) were previously identified as the invasion promoted genes of head and neck squamous cell carcinoma (HNSCC) by comparing the gene expression profiles between parent and a highly invasive clone. We have previously reported that Periostin and IFITM1 promoted the invasion of HNSCC cells. Here we demonstrated that Wnt-5b overexpression promoted the invasion of HNSCC cells. Moreover, stromelysin-2 (matrix metalloproteinase-10; MMP-10) was identified as a common up-regulated gene among Periostin, IFITM1 and Wnt-5b overexpressing HNSCC cells by using microarray data s…
Suspended particulate matter fluxes along with their associated metals, organic matter and carbonates in a coastal Mediterranean area affected by min…
2016
International audience; A study of suspended particulate matter (SPM) fluxes along with their associated metals, organic matter and carbonates, was conducted off the Mejerda River outlet in May 2011 and in March and July 2012 at depths of 10, 20 and 40 m using sediment traps. SPM fluxes are more significant near the Mejerda outlet, especially in winter, but dissipate further offshore. Normalization reveals that the Mejerda is a major source of Pb, Zn, Cd, Cu, Ni, and Co, all of which are the result of human activities. In contrast, Fe, Mn and N are of authigenic origin. The enrichment factor shows that Pb, Zn and especially Cd are the most highly polluting metals off the Mejerda outlet. Thi…
Autor, realitat i ficció en la narrativa de Jordi Sarsanedas
2013
L’article analitza el tractament de la figura de l’autor real en els reculls de narracions de Jordi Sarsanedas. En el primer, «Mites», el prefaci auctorial ha estat interpretat en clau autobiogràfica, a pesar de l’absència de marques explícites, de la ficcionalització amb què s’hi elaboren alguns dels elements i de l’enunciació a càrrec d’un jo que es projecta fantasmagòricament en els narradors autodiegètics de les narracions de ficció. En el darrer, «Una discreta venjança», l’estatus del prefaci auctorial és ambigu perquè es confon amb la metaficcionalitat dominant en el recull, sobretot a causa de l’ús de la metalepsi de l’autor. També s’hi analitza el tractament de la figura de l’autor …