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Disease-modifying drugs can reduce disability progression in relapsing multiple sclerosis
2020
Abstract An ever-expanding number of disease-modifying drugs for multiple sclerosis have become available in recent years, after demonstrating efficacy in clinical trials. In the real-world setting, however, disease-modifying drugs are prescribed in patient populations that differ from those included in pivotal studies, where extreme age patients are usually excluded or under-represented. In this multicentre, observational, retrospective Italian cohort study, we evaluated treatment exposure in three cohorts of patients with relapsing-remitting multiple sclerosis defined by age at onset: paediatric-onset (≤18 years), adult-onset (18–49 years) and late-onset multiple sclerosis (≥50 years). We…
Influence of Training Models at 3,900-m Altitude on the Physiological Response and Performance of a Professional Wheelchair Athlete: A Case Study.
2019
Sanz-Quinto, S, Lopez-Grueso, R, Brizuela, G, Flatt, AA, and Moya-Ramon, M. Influence of training models at 3,900-m altitude on the physiological response and performance of a professional wheelchair athlete: A case study. J Strength Cond Res 33(6): 1715-1723, 2019-This case study compared the effects of two training camps using flexible planning (FP) vs. inflexible planning (IP) at 3,860-m altitude on physiological and performance responses of an elite marathon wheelchair athlete with Charcot-Marie-Tooth disease (CMT). During IP, the athlete completed preplanned training sessions. During FP, training was adjusted based on vagally mediated heart rate variability (HRV) with specific sessions…
Patient and physician views on the quality of care in inflammatory bowel disease: Results from SOLUTION-1, a prospective IG-IBD study
2014
Remarkable differences in quality of care (QoC) might be observed in different countries, affecting quality of life of inflammatory bowel disease (IBD) patients. The aim of this study was to assess patient and physician perceptions of the QoC in Italy.A multicentre observational study on the quality of care in IBD (SOLUTION-1) was conducted in 36 IG-IBD (Italian Group for Inflammatory Bowel Disease) centres in Italy. The QUOTE-IBD (Quality of Care Through the Patient's Eyes) questionnaire was administered to IBD patients and to the attending physicians. The Quality Impact (QI) score summarises the QUOTE-IBD questionnaire, and a QI9 is considered satisfactory.Nine-hundred-ninety-two patients…
Patient education in physiotherapy in total hip arthroplasty (THA) - The perspective of physiotherapists
2018
Background and Purpose There is limited knowledge about patients’ and physiotherapists’ perceptions of patient education in physiotherapy in hip arthroplasty. The aim of this study was to describe physiotherapists’ conceptions of the patient education in physiotherapy needed by patients undergoing total hip arthroplasty. Methods The data for this qualitative study were collected using group and individual semi-structured interviews. Seven physiotherapists were interviewed. The research data were analyzed using a phenomenographic method. Results Three categories of patient education in physiotherapy in hip arthroplasty were produced and the categories formed a hierarchy. The narrowest descri…
Risk factors for clinical stress fractures in male military recruits: A prospective cohort study
2004
This prospective study was aimed at evaluating risk factors for symptomatic stress fractures among 179 Finnish male military recruits, aged 18 to 20 years. The subjects were studied in the very beginning of the military service of 6 to 12 months in summer. Bone mineral content (BMC) and density (BMD) were measured by dual energy X-ray absorptiometry (DXA) at the lumbar spine and at the hip and heel ultrasound investigation was performed. Blood was sampled for determination of serum total and free testosterone, total and free estradiol, sex hormone-binding globulin (SHBG), procollagen type I N propeptide, total and carboxylated osteocalcin, tartrate-resistant acid phosphatase 5b, 25-hydroxyv…
Associations of Physical Fitness and Body Composition Characteristics With Simulated Military Task Performance
2017
Pihlainen, K, Santtila, M, Hakkinen, K, and Kyrolainen, H. Associations of physical fitness and body composition characteristics with simulated military task performance. J Strength Cond Res 32(4): 1089-1098, 2018-The purpose of this study was to evaluate the associations of physical fitness and body composition characteristics with anaerobic endurance performance, tested in the combat load using the occupationally relevant military simulation test (MST). Eighty-one male soldiers, deployed to a crisis management operation in the Middle East, volunteered for the study and participated in a test battery consisting measurements of muscle strength, body composition characteristics, endurance ca…
Social, Occupational, and Cultural Adaptation During a 12-Month Wintering in Antarctica.
2016
Background and methods Life in isolated and confined environments (ICEs) is subject to important constraints which can generate psychosociologically impaired outcomes. This study investigated psychological, social, occupational, and cultural variables which are among the most important determinants in adaptation to a one-year wintering in Antarctica for 13 international subjects. Results Our findings confirm and give further insight into the role of social (Cohesiveness, Social Support) and occupational (Implementation/Preparedness, Counterproductive Activity, Decision Latitude, and Psychological Job Demands) dimensions of adaptation to ICEs. Relationships between various social and occupat…
Do Transgender People Respond According to Their Biological Sex or Their Gender Identity When Confronted With Romantic Rivals?
2019
This study examined the hypothesis that gender identity and biological sex represent independent modules and that transgender individuals respond to romantic rivals in line with their gender identity and not with their biological sex. Additionally, associations of jealousy with intrasexual competitiveness (ISC) and social comparison orientation (SCO) were explored. A total of 134 male-to-female and 94 female-to-male transgender individuals from Greater Buenos Aires, Argentina, responded to a questionnaire. In line with the predictions, female-to-male transgender individuals experienced more jealousy than male-to-female transgender individuals in response to a physically dominant rival, whe…
Human cooperation in groups: variation begets variation
2015
Open Access Published: 04 November 2015 Human cooperation in groups: variation begets variation Pieter van den Berg, Lucas Molleman, Jaakko Junikka, Mikael Puurtinen & Franz J. Weissing Scientific Reports volume 5, Article number: 16144 (2015) Cite this article 383 Accesses 4 Citations 6 Altmetric Metricsdetails Abstract Many experiments on human cooperation have revealed that individuals differ systematically in their tendency to cooperate with others. It has also been shown that individuals condition their behaviour on the overall cooperation level of their peers. Yet, little is known about how individuals respond to heterogeneity in cooperativeness in their neighbourhood. Here, we presen…
Gender-related differences in psychometric properties of WHO Disability Assessment Schedule 2.0
2019
Objective of this study was to investigate the gender-related differential item function of 12-item WHODAS 2.0 amongst patients with chronic musculoskeletal pain. This was a cross-sectional survey study among 1,988 patients at a university Physical and Rehabilitation Medicine outpatient clinic. To assess DIF, WHODAS 2.0 items were dichotomized as `none’ rated by respondents as `0’ versus `any limitation’ rated as `1,2,3 or 4’. The item response theory analysis was used to define discrimination and difficulty parameters of a questionnaire. The probit logistic regression was used to test uniformity of DIF between gender groups. The results of DIF analysis were presented and evaluated graphica…