Search results for " stratification"
showing 10 items of 144 documents
A proposed new model for prognostic stratification of poor-risk patients with metastatic renal cell carcinoma (mRCC) in the era of targeted therapy.
2014
e15588 Background: The stratification of poor risk mRCC patients in the era of targeted therapy represents an unmet medical need. We analyzed, individually, each prognostic factor included in modif...
Preoperative CT-Based Deep Learning Model for Predicting Risk Stratification in Patients With Gastrointestinal Stromal Tumors.
2021
ObjectiveTo develop and evaluate a deep learning model (DLM) for predicting the risk stratification of gastrointestinal stromal tumors (GISTs).MethodsPreoperative contrast-enhanced CT images of 733 patients with GISTs were retrospectively obtained from two centers between January 2011 and June 2020. The datasets were split into training (n = 241), testing (n = 104), and external validation cohorts (n = 388). A DLM for predicting the risk stratification of GISTs was developed using a convolutional neural network and evaluated in the testing and external validation cohorts. The performance of the DLM was compared with that of radiomics model by using the area under the receiver operating char…
La cattedrale di Catania-Catania Cathedral
2015
Il volume ripercorre le vicende secolari (dal Medioevo al Novecento) di una grande fabbrica stratificata dell'architettura siciliana: la cattedrale di Catania. La cattedrale normanna e il terremoto del 1169; gli innesti tardogotici e rinascimentali; il ruolo dei vescovi "costruttori" dopo la Controriforma; il terremoto del 1693 e la ricostruzione; il dibattito sulla nuova facciata progettata dall'architetto Giovan Battista Vaccarini; il completamenti del XIX secolo: cupola e campanile; la campagna di scavi e restauri del 1957, sono gli argomenti approfonditi dalla ricerca. Introduce un breve paragrafo sulla storia della città di Catania e delle sue architetture più significative costruite p…
Risk factors for central nervous system tumors in children: New findings from a case-control study
2017
BACKGROUND: Central nervous system tumors (CNS) are the most frequent solid tumor in children. Causes of CNS tumors are mainly unknown and only 5% of the cases can be explained by genetic predisposition. We studied the effects of environmental exposure on the incidence of CNS tumors in children by subtype, according to exposure to industrial and/or urban environment, exposure to crops and according to socio-economic status of the child. METHODS: We carried out a population-based case-control study of CNS tumors in Spain, covering 714 incident cases collected from the Spanish Registry of Childhood Tumors (period 1996-2011) and 4284 controls, individually matched by year of birth, sex, and au…
Transnational return and social change: hierarchies, identities and ideas
2020
The volume’s eight chapters are organized in three thematic sections: (I) Changing Social Hierarchies; (II) Reshaping Collective Identities; and (III) Questioning Ideas, Local Knowledge and Norms. ...
The multidimensional prognostic index (MPI) for the prognostic stratification of older inpatients with COVID-19: A multicenter prospective observatio…
2021
Background: The topic of prognosis in COVID-19 research may be important in adopting appropriate clinical decisions. Multidimensional prognostic index (MPI) is a frailty assessment tool widely used for stratifying prognosis in older people, but data regarding inpatients, affected by COVID-19, are not available. Objectives: To evaluate whether MPI can predict in-hospital mortality and the admission to intensive care unit (ICU) in older inpatients hospitalized for COVID-19 infection. Methods: In this longitudinal, Italian, multi-center study, older patients with COVID-19 were included. MPI was calculated using eight different domains typical of comprehensive geriatric assessment and categoriz…
Intergenerational support as a reaction to socio-economic crisis: alteration of solidarity within precarious Romanian households
2017
ABSTRACTThis paper addresses the tensions arising from the intersection of norms and practices of support in situations in which intergenerational support is the main household strategy for coping with precariousness in Romania. This paper describes competing meanings of solidarity and reveals gendered experiences of ambiguity with respect to the sustainability of help exchanges within the context of economic vulnerability. Romania displays high public acceptance of intergenerational support, while the country’s deficient social welfare system prompts families to intensify their help exchanges. Findings based on in-depth interviews suggest that private arrangements are compounded by unbalan…
Rationale, design and methods of CTCA-PRORECAD (Computed Tomography Coronary Angiography Prognostic Registry for Coronary Artery Disease): a multicen…
2013
PURPOSE: This study was done to assess the prognostic value of computed tomography coronary angiography (CTCA) in a large multicentre population of patients with suspected coronary artery disease (CAD) and, in particular, its incremental value compared with traditional methods for risk stratification. MATERIALS AND METHODS: This is a retrospective observational study that began in January 2003 conducted on patients with suspected CAD assessed with CTCA on the basis of symptoms (chest pain, dyspnoea) and/or abnormal or equivocal stress test and/or a high cardiovascular risk profile. The participating centres will provide data obtained with CTCA performed with 16-slice or higher equipment. Ex…
The relationship between health-related quality of life and melancholic depressive symptoms is modified by brain insulin receptor gene network
2021
AbstractTo investigate whether expression-based polygenic risk scores for the insulin receptor gene network (ePRS-IRs) modifiy the association between type of depressive symptoms and health-related quality of life (HRQoL). This cross-sectional study includes 1558 individuals from the Helsinki Birth Cohort Study. Between 2001 and 2004, the Short Form-36 questionnaire was employed to assess mental and physical components of HRQoL and Beck Depression Inventory (BDI) to assess depressive symptoms. Depressive symptoms were categorized into minimal (BDI < 10), non-melancholic and melancholic types of depression. The ePRS-IRs were calculated for the hippocampal (hePRS-IR) and the mesocorticolim…
Romanian Households Dealing with Precariousness: A life-course approach
2016
This paper addresses the main pathways through which households avoid slipping into poverty in Romania by employing a life-course approach. Recent researches on social stratification found that in every country we can delineate a particular social layer composed of households living just above the poverty threshold, whose members struggle to reach a more secure prosperity while facing constant threats of downward mobility. Drawing on recent precarious prosperity research, and based on in-depth interviews carried out in 2013 with 25 households situated in between poverty and prosperity from a Romanian city (Cluj-Napoca), we use a life-course approach in order to account for the main routes i…