Search results for " virus infection"

showing 10 items of 135 documents

Prognostic Impact of Hyponatremia and Hypernatremia in COVID-19 Pneumonia. A HOPE-COVID-19 (Health Outcome Predictive Evaluation for COVID-19) Regist…

2020

Dysnatremia is associated with increased mortality in patients with community-acquired pneumonia. SARS-COV2 (Severe-acute-respiratory syndrome caused by Coronavirus-type 2) pneumonia can be fatal. The aim of this study was to ascertain whether admittance dysnatremia is associated with mortality, sepsis, or intensive therapy (IT) in patients hospitalized with SARS-COV2 pneumonia. This is a retrospective study of the HOPE-COVID-19 registry, with data collected from January 1th through April 31th, 2020. We selected all hospitalized adult patients with RT-PCR-confirmed SARS-COV2 pneumonia and a registered admission serum sodium level (SNa). Patients were classified as hyponatremic (SNa <…

MalehyponatremiaEndocrinology Diabetes and Metabolism030204 cardiovascular system & hematologyGlobal Healthlcsh:Diseases of the endocrine glands. Clinical endocrinology:Health Care::Health Care Quality Access and Evaluation::Quality of Health Care::Health Care Evaluation Mechanisms::Outcome and Process Assessment (Health Care) [Medical Subject Headings]:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]sepsis0302 clinical medicineEndocrinology:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies::Retrospective Studies [Medical Subject Headings]HiponatremiaOutcome Assessment Health CareSARS-COV2Hospital MortalityRegistriesOriginal Research:Persons::Persons::Age Groups::Adult::Aged [Medical Subject Headings]:Health Care::Environment and Public Health::Public Health::Epidemiologic Methods::Data Collection::Registries [Medical Subject Headings]HypernatremiahypernatremiaMiddle AgedPrognosisVirusHospitalizationSurvival Rate:Analytical Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Patient Care::Hospitalization [Medical Subject Headings]HipernatremiaFemaleHyponatremiaHyponatremiamedicine.medical_specialty:Information Science::Information Science::Data Collection::Vital Statistics::Mortality::Survival Rate [Medical Subject Headings]Coronavirus disease 2019 (COVID-19)Infecciones por coronavirus:Check Tags::Male [Medical Subject Headings]030209 endocrinology & metabolismSepsis03 medical and health sciencesInternal medicineSepsis:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies::Longitudinal Studies::Follow-Up Studies [Medical Subject Headings]medicineHumans:Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Water-Electrolyte Imbalance::Hypernatremia [Medical Subject Headings]MortalitySurvival rateAgedRetrospective Studieslcsh:RC648-665business.industrySARS-CoV-2COVID-19Retrospective cohort study:Persons::Persons::Age Groups::Adult::Middle Aged [Medical Subject Headings]Aparato respiratoriomedicine.diseasemortality:Diseases::Virus Diseases::RNA Virus Infections::Nidovirales Infections::Coronaviridae Infections::Coronavirus Infections [Medical Subject Headings]Clinical trialbody regionsPneumonia:Check Tags::Female [Medical Subject Headings]:Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Water-Electrolyte Imbalance::Hyponatremia [Medical Subject Headings]Mortalidad:Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis [Medical Subject Headings]:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Vital Statistics::Mortality::Hospital Mortality [Medical Subject Headings]HypernatremiabusinessFollow-Up Studies
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Viral Infections in Neonates with Suspected Late-Onset Bacterial Sepsis—A Prospective Cohort Study

2016

Objective The aim of our study was to evaluate the occurrence of viral infections in infants with suspected late-onset bacterial sepsis in a neonatal intensive care unit. Methods In a prospective study, infants with suspected late-onset bacterial sepsis underwent viral testing alongside routine blood culture sampling. Using a multiplex reverse transcription-polymerase chain reaction enzyme-linked immunosorbent assay, nasopharyngeal aspirates were analyzed for adenovirus, respiratory syncytial virus (RSV), influenza virus A and B, H1N1 virus, parainfluenza virus 1 to 4, metapneumovirus, coronavirus, and picornavirus. Stools were examined for adenovirus, rotavirus, norovirus, and enterovirus.…

MalevirusesBacteremiamedicine.disease_causeLate Onset DisordersAdenovirus Infections HumanCohort StudiesFeces0302 clinical medicineRotavirusGermanyNasopharynxBlood culture030212 general & internal medicineProspective StudiesCoronavirusCaliciviridae InfectionsParamyxoviridae InfectionsNeonatal sepsismedicine.diagnostic_testReverse Transcriptase Polymerase Chain ReactionObstetrics and Gynecologyvirus diseasesVirus DiseasesOriginal ArticleFemaleNeonatal SepsisCoronavirus InfectionsEnzyme-Linked Immunosorbent AssayvirusRespiratory Syncytial Virus InfectionsRotavirus InfectionsSepsis03 medical and health sciences030225 pediatricsIntensive Care Units NeonatalInfluenza HumanmedicineEnterovirus InfectionsHumanslate-onset bacterial sepsisPicornaviridae Infectionsbusiness.industryInfant Newbornmedicine.diseaseVirologyneonatal intensive care unitinfectionBlood CultureBacteremiaPediatrics Perinatology and Child HealthImmunologyNorovirusEnterovirusbusinessMultiplex Polymerase Chain ReactionAmerican Journal of Perinatology
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Detection of Human Papillomavirus DNA in Cervical Samples: Analysis of the New PGMY-PCR Compared To the Hybrid Capture II and MY-PCR Assays and a Two…

2004

ABSTRACT The PGMY-PCR for human papillomavirus (HPV) was evaluated, in parallel with nested PCR ( n PCR), in samples with noted Hybrid Capture II (HCII) and MY-PCR results. PGMY-PCR detected HPV DNA in 2.5% of HCII-negative-MY-PCR-negative samples and in 71.7% of HCII-positive-MY-PCR-negative samples; also, it detected the MY-PCR-negative- n PCR-negative types HPV-42, HPV-44, HPV-51, HPV-87, and HPV-89.

Microbiology (medical)GenotypeTwo stepPcr assayCervix UteriBiologyPolymerase Chain ReactionSensitivity and Specificitylaw.inventionlawVirologyHuman papillomavirus DNAHumansHuman papillomavirusPapillomaviridaePolymerase chain reactionPapillomavirus InfectionsHybrid capturevirus diseasesVirologyMolecular biologyfemale genital diseases and pregnancy complicationsTumor Virus InfectionsHpv testingDNA ViralFemaleNested polymerase chain reactionJournal of Clinical Microbiology
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Evaluation of the Architect Epstein-Barr Virus (EBV) Viral Capsid Antigen (VCA) IgG, VCA IgM, and EBV Nuclear Antigen 1 IgG Chemiluminescent Immunoas…

2014

ABSTRACTCommercial immunoassays for detecting IgG and IgM antibodies against Epstein-Barr virus (EBV), viral capsid antigens (VCA), and IgGs toward EBV nuclear antigen-1 (EBNA-1) are routinely used in combination to categorize EBV infection status. In this study, we evaluated the performances of the Architect EBV VCA IgG, VCA IgM, and EBNA-1 IgG chemiluminescent microparticle assays (CMIAs) in EBV serological analyses using indirect immunofluorescence assays and anticomplement immunofluorescence assays as the reference methods for VCA IgG, VCA IgM, and EBNA-1 IgG antibody detection, respectively. A total of 365 serum samples representing different EBV serological profiles were included in t…

Microbiology (medical)MaleEpstein-Barr Virus InfectionsHerpesvirus 4 HumanClinical BiochemistryImmunologyFluorescent Antibody Techniquemedicine.disease_causeImmunofluorescenceAntibodies ViralSensitivity and SpecificityImmunoglobulin GSerologyAntigenhemic and lymphatic diseasesDiagnostic Laboratory Immunologyotorhinolaryngologic diseasesImmunology and AllergyMedicineHumansChildAntigens ViralImmunoassaymedicine.diagnostic_testbiologybusiness.industryDiagnostic Tests RoutineInfantVirologyEpstein–Barr virusstomatognathic diseasesEpstein-Barr Virus Nuclear AntigensImmunoglobulin MImmunoglobulin MImmunoassayChild PreschoolImmunoglobulin GImmunologyLuminescent Measurementsbiology.proteinCapsid ProteinsFemaleAntibodybusiness
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Acalculous cholecystitis during the course of acute Epstein–Barr virus infection and Gilbert's syndrome

2009

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Microbiology (medical)business.industryAcalculous cholecystitisUridine metabolismGeneral MedicineEBV; cholecystitismedicine.diseaseGilbert's syndromeVirologyInfectious DiseasesEBVcholecystitismedicineCholecystitisGilbert DiseasebusinessEpstein–Barr virus infectionInternational Journal of Infectious Diseases
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Human Immunodeficiency Virus Infection and Diverse Physical Health Outcomes: An Umbrella Review of Meta-analyses of Observational Studies.

2019

Abstract Background Our aim was to assess both the credibility and strength of evidence arising from systematic reviews with meta-analyses of observational studies and physical health outcomes associated with human immunodeficiency virus (HIV) but not acquired immunodeficiency syndrome. Methods We performed an umbrella review of observational studies. Evidence was graded as convincing, highly suggestive, suggestive, weak, or nonsignificant. Results From 3413 studies returned, 20 were included, covering 55 health outcomes. Median number of participants was 18 743 (range 403–225 000 000). Overall, 45 (81.8%) of the 55 unique outcomes reported nominally significant summary results (P < .05). O…

Microbiology (medical)medicine.medical_specialtyPopulationcomorbidHIV InfectionsDisease03 medical and health sciencesPulmonary Disease Chronic Obstructive0302 clinical medicineAcquired immunodeficiency syndrome (AIDS)Meta-Analysis as TopicPre-EclampsiaPregnancyInternal medicineMedicineHumanshealth outcomes030212 general & internal medicineeducationArticles and CommentariesCOPDeducation.field_of_studyhuman immunodeficiency virusumbrella reviewbusiness.industryhuman immunodeficiency viruPublic healthIncidence (epidemiology)IncidenceAn Umbrella Review of Meta-analyses of Observational Studies.- Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2019 [Grabovac I. Veronese N. Stefanac S. Haider S. Jackson S. Koyanagi A. Meilinger M. Stubbs B. Firth J. Soysal P. et al. -Human Immunodeficiency Virus Infection and Diverse Physical Health Outcomes]HIVmedicine.diseaseComorbidityObservational Studies as TopicInfectious DiseasesCross-Sectional StudiesAcademicSubjects/MED00290health outcomeFemalebusiness030217 neurology & neurosurgeryCohort studySystematic Reviews as TopicClinical infectious diseases : an official publication of the Infectious Diseases Society of America
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Risk factors and interventional strategies for BK polyomavirus infection after renal transplantation.

2012

BK virus (BKV)-induced viraemia after renal transplantation can be associated with severe impairment of graft function. This study evaluated possible risk factors for BKV replication and examined the outcomes following various currently used treatment approaches.Fifty-seven renal transplant recipients with BKV viraemia were retrospectively compared with 71 BKV-negative recipients to identify risk factors for BKV viraemia. Furthermore, outcome and graft function in 14 patients with BKV replication, in whom mycophenolate mofetil (MMF) was discontinued with a dose reduction of the remaining immunosuppressants, were compared with 32 patients in whom both MMF and the additional immunosuppressant…

NephrologyAdultMalemedicine.medical_specialtyvirusesUrologyLymphocytemedicine.medical_treatmentPrednisoloneAnti-Inflammatory AgentsKaplan-Meier Estimatemedicine.disease_causeVirus ReplicationGastroenterologyTacrolimusRisk FactorsInternal medicineConfidence IntervalsOdds RatioMedicineHumansLymphocyte CountWarm IschemiaRetrospective StudiesPolyomavirus Infectionsbusiness.industryGraft Survivalvirus diseasesImmunosuppressionOdds ratioMiddle AgedMycophenolic AcidViral LoadKidney TransplantationTacrolimusBK virusTransplantationTumor Virus Infectionsmedicine.anatomical_structureNephrologyBK VirusImmunologyCyclosporineDrug Therapy CombinationFemalebusinessViral loadImmunosuppressive AgentsScandinavian journal of urology and nephrology
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Human papillomavirus (HPV) DNA in primary cervical cancer and in cancer free pelvic lymph nodes--correlation with clinico-pathological parameters and…

2001

OBJECTIVE To assess whether the presence of human papilloma virus (HPV) DNA and/or several genotypes of HPV DNA in primary cervical cancer and cancer free pelvic lymph nodes are correlated with several clinicopathological parameters of well-defined prognostic significance and whether virological parameters are predictors of long-term survival in cancer patients. PATIENTS AND METHODS 223 cases of cervical cancer patients included in this retrospective study underwent follow-up evaluation. Survival and cause of death were examined for 204 (91.4%) patients, with a mean follow-up time of 4.4 years. HPV DNA was detected using the high sensitive polymerase chain reaction (PCR) method followed by …

OncologyAdultmedicine.medical_specialtyGenotypeUterine Cervical NeoplasmsAdenocarcinomaPolymerase Chain Reactionlaw.inventionCarcinoma AdenosquamouslawInternal medicineGenotypeMedicineHumansNeoplasm InvasivenessLymph nodePapillomaviridaePolymerase chain reactionAgedRetrospective StudiesCervical cancerAged 80 and overbusiness.industryPapillomavirus InfectionsObstetrics and GynecologyCancerMiddle Agedmedicine.diseasePrognosisPrimary tumorSurvival AnalysisKoilocyteTumor Virus Infectionsmedicine.anatomical_structureLymphatic MetastasisDNA ViralCarcinoma Squamous CellFemaleLymphLymph NodesbusinessFollow-Up StudiesZentralblatt fur Gynakologie
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The presence of HPV DNA in cervical cancer: correlation with clinico-pathologic parameters and prognostic significance: 10 years experience at the De…

2001

The objective of this study was to assess whether the presence of human papillomavirus (HPV) DNA and/or several genotypes of HPV DNA in cervical cancer are correlated with several clinicopathologic parameters of well-defined prognostic significance and whether virologic parameters are predictors of long-term survival in cancer patients. Two hundred twenty three cases of cervical cancer patients included in this retrospective study underwent follow-up evaluation. Survival and cause of death were examined for 204 (91.4%) patients, with a mean follow-up time of 4.4 years. HPV DNA was detected using the highly sensitive polymerase chain reaction (PCR) method followed by HPV DNA sequencing for H…

OncologyAdultmedicine.medical_specialtyGenotypeUterine Cervical NeoplasmsAdenocarcinomaPolymerase Chain Reactionlaw.inventionCarcinoma AdenosquamouslawInternal medicineGenotypemedicineCarcinomaHumansPapillomaviridaePapillomaviridaeSurvival analysisPolymerase chain reactionAgedRetrospective StudiesGynecologyCervical cancerAged 80 and overbiologybusiness.industryPapillomavirus Infectionsvirus diseasesObstetrics and GynecologyCancerMiddle Agedmedicine.diseasebiology.organism_classificationPrognosisSurvival Analysisfemale genital diseases and pregnancy complicationsTumor Virus InfectionsOncologyDNA ViralCarcinoma Squamous CellAdenocarcinomaFemalebusinessInternational journal of gynecological cancer : official journal of the International Gynecological Cancer Society
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Exposure to UV radiation and risk of Hodgkin lymphoma: A pooled analysis

2013

Ultraviolet radiation (UVR) exposure has been inversely associated with Hodgkin lymphoma (HL) risk, but only inconsistently, only in a few studies, and without attention to HL heterogeneity. We conducted a pooled analysis of HL risk focusing on type and timing of UVR exposure and on disease subtypes by age, histology, and tumor-cell Epstein-Barr virus (EBV) status. Four case-control studies contributed 1320HLcasesand 6381 controls. We estimated lifetime, adulthood, and childhood UVR exposure and history of sunburn and sunlamp use. We used 2-stage estimation with mixed-effects models and weighted pooled effect estimates by inverse marginal variances. We observed statistically significant inv…

OncologyMaleEpstein-Barr Virus InfectionsDNA RepairSunburnSkin PigmentationComorbidityBiochemistryT-Lymphocytes Regulatoryvisual_art.visual_artistimmune system diseaseshemic and lymphatic diseasesYoung adultSunburnAged 80 and overLymphoid NeoplasiaSunbathingintegumentary systemExposure CategoryInside BLOODConfoundingAge FactorsConfounding Factors EpidemiologicHematologyMiddle AgedHodgkin DiseaseEuropeHodgkin lymphoma (HL)visual_artSunlightFemaleAdultmedicine.medical_specialtyAdolescentUltraviolet RaysImmunologyBiologyWhite PeopleYoung AdultSunbathingInternal medicinemedicineHumansUltraviolet radiation (UVR)tumor-cell Epstein-Barr virus (EBV)AgedfungiCase-control studyModels ImmunologicalDose-Response Relationship RadiationCell BiologyOdds ratiomedicine.diseaseRelative riskCase-Control StudiesImmunologyDNA Damage
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