Search results for "ARTICLES"
showing 10 items of 9626 documents
3D polylactide-based scaffolds for studying human hepatocarcinoma processes in vitro
2012
We evaluated the combination of leaching techniques and melt blending of polymers and particles for the preparation of highly interconnected three-dimensional polymeric porous scaffolds for in vitro studies of human hepatocarcinoma processes. More specifically, sodium chloride and poly(ethylene glycol) (PEG) were used as water-soluble porogens to form porous and solvent-free poly(L,D-lactide) (PLA)-based scaffolds. Several characterization techniques, including porosimetry, image analysis and thermogravimetry, were combined to improve the reliability of measurements and mapping of the size, distribution and microarchitecture of pores. We also investigated the effect of processing, in PLA-ba…
A synthetic biology approach for the fabrication of functional (fluorescent magnetic) bioorganic–inorganic hybrid materials in sponge primmorphs
2020
During evolution, sponges (Porifera) have honed the genetic toolbox and biosynthetic mechanisms for the fabrication of siliceous skeletal components (spicules). Spicules carry a protein scaffold embedded within biogenic silica (biosilica) and feature an amazing range of optical, structural, and mechanical properties. Thus, it is tempting to explore the low-energy synthetic pathways of spiculogenesis for the fabrication of innovative hybrid materials. In this synthetic biology approach, the uptake of multifunctional nonbiogenic nanoparticles (fluorescent, superparamagnetic) by spicule-forming cells of bioreactor-cultivated sponge primmorphs provides access to spiculogenesis. The ingested nan…
Selective Actuation and Tomographic Imaging of Swarming Magnetite Nanoparticles
2021
International audience; Micro- and nanomotors have seen substantial progress in recent years for biomedical applications. However, three grand challenges remain: (i) high velocities to overcome the blood flow, (ii) spatially selective control to enable complex navigation, and (iii) integration of a medical, tomographic real-time imaging method to acquire feedback information. Here, we report the combination of active magnetic matter and a medical imaging technique, namely magnetic particle imaging (MPI), which addresses these needs. We synthesize ∼200 nm magnetic nanoparticles and observe a macroscopic, collective effect in a homogeneous magnetic field with a rotating field vector. The nano…
A high-resolution PET demonstrator using a silicon "magnifying glass".
2021
Abstract To assist ongoing investigations of the limits of the tradeoff between spatial resolution and noise in PET imaging, several PET instruments based on silicon-pad detectors have been developed. The latest is a segment of a dual-ring device to demonstrate that excellent reconstructed image resolution can be achieved with a scanner that uses highresolution detectors placed close to the object of interest or surrounding a small field-of-view in combination with detectors having modest resolution at larger radius. The outer ring of our demonstrator comprises conventional BGO block detectors scavenged from a clinical PET scanner and located at a 500 mm radius around a 50 mm diameter field…
Deuteron form factor measurements at low momentum transfers
2016
A precise measurement of the elastic electron-deuteron scattering cross section at four-momentum transfers of 0.24 fm−1 ≤ Q ≤ 2.7 fm−1 has been performed at the Mainz Microtron. In this paper we describe the utilized experimental setup and the necessary analysis procedure to precisely determine the deuteron charge form factor from these data. Finally, the deuteron charge radius rd can be extracted from an extrapolation of that form factor to Q 2 = 0.
XENON100 dark matter results from a combination of 477 live days
2016
We report on WIMP search results of the XENON100 experiment, combining three runs summing up to 477 live days from January 2010 to January 2014. Data from the first two runs were already published. A blind analysis was applied to the last run recorded between April 2013 and January 2014 prior to combining the results. The ultra-low electromagnetic background of the experiment, ~$5 \times 10^{-3}$ events/(keV$_{\mathrm{ee}}\times$kg$\times$day) before electronic recoil rejection, together with the increased exposure of 48 kg $\times$ yr improves the sensitivity. A profile likelihood analysis using an energy range of (6.6 - 43.3) keV$_{\mathrm{nr}}$ sets a limit on the elastic, spin-independe…
Polarization of τ in quasielastic (anti)neutrino scattering: The role of spectral functions
2019
We present a study of the $\tau$ polarization in charged-current quasielastic (anti)neutrino-nucleus scattering. The spectral function formalism is used to compute the differential cross section and the polarization components for several kinematical setups, relevant for neutrino-oscillation experiments. The effects of the nuclear corrections in these observables are investigated by comparing the results obtained using two different realistic spectral functions, with those deduced from the relativistic global Fermi gas model, where only statistical correlations are accounted for. We show that the spectral functions, although they play an important role when predicting the differential cross…
The role of vector-baryon channels and resonances in the γp→K0Σ+ and γn→K0Σ0 reactions near the K⁎Λ threshold
2013
Abstract We have studied the γ p → K 0 Σ + reaction in the energy region around the K ⁎ Λ and K ⁎ Σ thresholds, where the CBELSA/TAPS cross section shows a sudden drop and the differential cross section experiences a transition from a forward-peaked distribution to a flat one. Our coupled-channel model incorporates the dynamics of the vector meson–baryon interaction which is obtained from the hidden gauge formalism. We find that the cross section in this energy region results from a delicate interference between amplitudes having K ⁎ Λ and K ⁎ Σ intermediate states. The sharp downfall is dictated by the presence of a nearby N ⁎ resonance produced by our model, a feature that we have employe…
Measurement ofΥ(1S+2S+3S)production inp+pand Au + Au collisions atsNN=200GeV
2015
Measurements of bottomonium production in heavy-ion and p + p collisions at the Relativistic Heavy Ion Collider (RHIC) are presented. The inclusive yield of the three states, (1S + 2S + 3S), was measured in the PHENIX experiment via electron-positron decay pairs at midrapidity for Au + Au and p + p collisions at root sNN = 200 GeV. The (1S + 2S + 3S) -> e(+)e(-) differential cross section at midrapidity was found to be B(ee)d sigma/dy = 108 +/- 38 (stat) +/- 15 (syst) +/- 11 (luminosity) pb in p + p collisions. The nuclear modification factor in the 30% most central Au + Au collisions indicates a suppression of the total. state yield relative to the extrapolation from p + p collision data. …
Production ofψ(2S)mesons inpp¯collisions at 1.96 TeV
2009
We have measured the differential cross section for the inclusive production of $\ensuremath{\psi}(2\mathrm{S})$ mesons decaying to ${\ensuremath{\mu}}^{+}{\ensuremath{\mu}}^{\ensuremath{-}}$ that were produced in prompt or $B$-decay processes from $p\overline{p}$ collisions at 1.96 TeV. These measurements have been made using a data set from an integrated luminosity of $1.1\text{ }\text{ }{\mathrm{fb}}^{\ensuremath{-}1}$ collected by the CDF II detector at Fermilab. For events with transverse momentum ${p}_{T}(\ensuremath{\psi}(2\mathrm{S}))g2\text{ }\text{ }\mathrm{GeV}/c$ and rapidity $|y(\ensuremath{\psi}(2\mathrm{S}))|l0.6$ we measure the integrated inclusive cross section $\ensuremath…