Search results for "Aortic"

Genetic contribution in sporadic thoracic aortic aneurysm? Emerging evidence of genetic variants related to TLR-4-mediated signaling pathway as risk …

2015

Abstract Sporadic thoracic aortic aneurysms (TAA) and dissections are one of the major causes of morbidity and mortality worldwide, especially in those older than 65 years. The presentation of TAA is varied and often silent. Thus, sporadic TAA detection is often fortuitous, with identification occurring during a routine physical examination or during an unrelated medical evaluation. Once suspected, confirmation by imaging clinical approaches is needed to allow the choose of the unique treatments for TAA, namely the surgery procedures, including elective surgery or endovascular repair before the onset of catastrophic and fatal complications, such as dissection or rupture. At present, there a…

Statin therapy in patients with aortic stenosis after the ASTRONOMER trial: is there still any space?

2011

L’associazione tra stiffness aortica e proteina C-reattiva è indipendente dalla microalbuminuria nell’ipertensione essenziale

2008

TCT-43 First-in-human experience of a novel transradial device for embolic deflection during transcatheter aortic valve replacement

2018

The average stroke rate in contemporary transcatheter aortic valve replacement (TAVR) studies is 4.4%. The majority of the TAVR studies are non-randomized registries, hence, neurological outcomes may be underreported. Over 50% of all TAVR related strokes occur during the procedure or on the same day

The Impact of Obesity on the Outcome of Surgical Repair for Acute Type A Aortic Dissection

2019

Intravascular ultrasound imaging of arterial wall architecture.

1992

Intravascular ultrasound (IVUS) is a promising new technique for assessing vascular morphology and structure. Controversy exists whether the three-layer appearance of the arterial wall correctly reflects the histologic structures of the intima, media, and adventitia. We performed an experimental study to clarify the three-layer appearance. The vessel wall architecture was analyzed by IVUS on eight different kinds of plastic cylinders, 24 normal blood vessels from pigs, and 59 human arterial segments. A distinct three-layer appearance was observed on all the plastic cylinders when the ultrasound beam was perpendicular to the wall. A three-layer appearance was also seen in the arterial wall, …

Patient-Specific Analysis of Ascending Thoracic Aortic Aneurysm with the Living Heart Human Model

2021

In ascending thoracic aortic aneurysms (ATAAs), aneurysm kinematics are driven by ventricular traction occurring every heartbeat, increasing the stress level of dilated aortic wall. Aortic elongation due to heart motion and aortic length are emerging as potential indicators of adverse events in ATAAs

Biomechanics of human ascending aorta and aneurysm rupture risk assessment

2021

Ascending aortic aneurysms (AsAA) and aortic dissections are life-threatening cardiovascular diseases. The main criteria for determining surgical intervention of AsAA are the maximum diameter or the increasing annual rate of the aneurysm. The mortality of the untreated aortic dissection can be 21% to 74%, depending on the delay of hospital admission.Our study aims to characterize the biomechanical properties of the ascending aorta and propose a patient-specific approach to assess the risks of rupture. The purpose of this PhD work is multifold.On the one hand, biaxial tensile tests were performed on AsAA samples obtained from one hundred patients with surgery of AsAA. The impact on the diffe…

Comprehensive cardiovascular ECG-gated MDCT as a standard diagnostic tool in patients with acute chest pain

2007

Acute myocardial infarction, pulmonary embolism, and aortic dissection are diseases associated with acute chest pain and may lead to severe morbidity and mortality. These diseases may not be trivial to diagnose in the settings of emergency room. ECG-gated multi-detector computed tomography (MDCT), already established for the assessment of pulmonary embolism and aortic dissection, provides reliable information regarding the triage of patients with acute coronary syndrome in the emergency room. MDCT recently appeared to be logistically feasible and a promising comprehensive method for the evaluation of cardiac and non-cardiac chest pain in emergency department patients. The possibility to sca…

What are the benefits of a minimally invasive approach in frail octogenarian patients undergoing aortic valve replacement?

2016

Not available