Search results for "Axe"
showing 10 items of 550 documents
Insults, humour and freedom of speech
2016
In this article we argue that freedom of speech should be understood as a social freedom. In the public discussion after the Charlie Hebdo attacks, it has often been understood as an absolute right to say anything – to offend, to make a fool of others and of oneself, and to express any opinion regardless of the consequences. We challenge this view and propose that advocating freedom of speech without understanding its social foundations is misleading and counterproductive. Based on the critical social theories of Erich Fromm, Charles Taylor and Axel Honneth, we show that there is an alternative tradition in which freedom is fundamentally rooted in social relations and therefore requires re…
Tipología y patrones de los bulos difundidos durante la pandemia de la covid-19 sobre salud y nutrición
2022
This study aims to identify the typology and patterns of hoaxes related to health and nutrition disseminated during the first stage of the COVID-19 pandemic (March-November 2020). To do this, an exploratory quantitative study was carried out with two data types. The first data comes from studying 95 documents (scientific articles) found in the SCOPUS database through Boolean searches with the terms (dis)misinformation, hoax, health, and nutrition. A registration form was used for these documents, indicating the following items: a) topic of the article (health or nutrition); b) the type of wrong message (misinformation or hoax); c) the country in which the study was done; d) the type of part…
Edward W. Said : le scientifique et le biographique
2014
Lorsqu’il publie Out of Place en 1999, Said n’est pas le premier chercheur a livrer des memoires au public, mais il livre toutefois des confidences fort intimes plutot inattendues. C’est tout l’interet de ce livre qui raconte sa vie entre 1935, annee de sa naissance, et 1962, annee de son doctorat. Notre but n’est pas de reduire la pensee de Said aux conditions de sa vie mais de montrer quels etaient les differents possibles qui se presentaient a lui. Car rien n’etait joue : a la souffrance des dechirements identitaires, il etait possible d’apporter d’autres reponses, bien plus agressives et dangereuses, que la deconstruction des identites alienantes transformees en outils de domination. Di…
Low doses of paclitaxel potently induce apoptosis in human retinoblastoma Y79 cells by up-regulating E2F1.
2008
Paclitaxel (PTX) is an anticancer drug currently in phase II clinical trials. This study shows for the first time that low doses of PTX (5 nM) potently induce apoptosis in human retinoblastoma Y79 cells. The effect of PTX is accompanied by a potent induction of E2F1 which appears to play a critical role in the effects induced by PTX. PTX induced a dose- and time-dependent effect, with G2/M arrest, cyclines A, E and B1 accumulation and a marked modification in the status of Cdc2-cyclin B1 complex, the major player of the G2/M checkpoint. Apoptosis followed G2/M arrest. An early and prolonged increase in p53 expression with its stabilization by phosphorylation and acetylation and its nuclear …
Bronchial microbiome of severe COPD patients colonised by Pseudomonas aeruginosa
2014
The bronchial microbiome in severe COPD during stability and exacerbation in patients chronically colonised by Pseudomonas aeruginosa (PA), has not been defined. Our objective was to determine the characteristics of the bronchial microbiome of severe COPD patients colonised and not colonised by P. aeruginosa and its changes during exacerbation. COPD patients with severe disease and frequent exacerbations were categorised according to chronic colonisation by P. aeruginosa. Sputum samples were obtained in stability and exacerbation, cultured, and analysed by 16S rRNA gene amplification and pyrosequencing. Sixteen patients were included, 5 of them showing chronic colonisation by P. aeruginosa.…
Analysis of microbiota in stable patients with chronic obstructive pulmonary disease
2014
To identify the bacterial diversity (microbiota) in expectorated sputum, a pyrosequencing method that investigates complex microbial communities of expectorated sputum was done in 19 stable chronic obstructive pulmonary disease patients (mean (SD) FEV1: 47 (18%) of predicted value). Using conventional culture, 3 phyla and 20 bacterial genera were identified, whereas the pyrosequencing approach detected 9 phyla and 43 genera (p < 0.001). In sputum the prevalent genera with pyrosequencing approach were Streptococcus, Actinomyces, Neisseria, Haemophilus, Rothia, Fusobacterium, Gemella, Granulicatella, Porphyromonas, Prevotella and Veillonella. Enterobacteriaceae, detected frequently in convent…
Peripheral olfactory function in rats after chemotherapeutic treatment with the anticancer drug docetaxel
2008
International audience; Clinical studies have documented that chemotherapeutic cancer treatment in humans is often associated with weight loss and decreased enjoyment of food. Beside taste, olfaction plays a role in the food intake regulation. We assessed whether hemotherapeutic cancer treatment compromises olfactory function in rats treated with docetaxel (Taxotere, TAX), an antineoplastic drug which disrupts the structures necessary for cell survival and division. Electroolfactogram responses (EOG) can indicate morpho-pathological changes in olfactory epithelium. Male rats received either a single, two or three intravenous injections (one per week) of an estimated 10% lethal dose (LD10) o…
Condylar position indicator and T-scan system II in clinical evaluation of temporomandibular intracapsular disease.
2012
The pathogenesis of temporomandibular joint intracapsular disease (TMJI) is multifactorial and its diagnosis is not easy. In this work authors show two types of clinical analysis: the Condylar Position Indicator (CPI) and T-Scan 2 system.Twenty patients (mean age of 24.5 years) with TMJI problem and 10 healthy matched subjects (mean age: 25.4 years) were selected. Analysis of TMJI was performed on each patient by means of Condylar Position Indicator (CPI) and T-Scan System II tests.Eight patients presented vertical symmetrical condylar distraction greater than healthy subjects (P-value0.001). T-Scan showed a difference of Percentage of Force (POF) not greater than 5%. Seven patients showed …
Les grammaires de construction au service de la morphologie lexicale ? Apports pour la description des noms-termes en allemand
2019
International audience; Contexte Le « goût » de la langue allemande pour la créativité lexicale, en particulier dans le domaine nominal, fait figure de lapalissade. Ceci est particulièrement vrai en discours spécialisés où les besoins en dénomination de nouveaux concepts passent, outre les différentes formes d’emprunts ou de néologismes de forme, par les deux procédés classiques que sont la dérivation et la composition. C’est dans ce contexte que la présente proposition de communication vise à interroger les apports des grammaires de construction appliquées à ces phénomènes – on parlera alors avec Booij (2017) de morphologie constructionnelle – pour une analyse de l’interface syntaxe-séma…
Linéarisation et expressivité dans un type de texte spécialisé : le compte rendu boursier
2006
This paper aims to answer the following two questions: is expressivity – defined by Jakobson (1963) as one of the six functions of language – a suitable category to describe specialized discourse? And if yes, what could the possible markers for this category be at the syntactical level? The analysed corpus is made up of comparable texts, actually stock exchange reports from the online versions of French and German daily newspapers. On the basis of Fix's notion of ‘text model' (Textmuster), we first give a succinct description of the thematic and textual features of these texts before briefly exploring which possibilities German syntax offers for the manifestation of expressivity. The main p…