Search results for "Boar"

Ortodoncia lingual y ortodoncia vestibular: estudio comparativo de la selección de casos y la calidad de terminación

2017

Las malposiciones dentales tienen un impacto significativo sobre la estética de la sonrisa y, por tanto, se considera un factor clave que afecta de forma directa a la autoestima. El objetivo principal de un tratamiento de ortodoncia es conseguir una oclusión ideal, que sea morfológicamente estable a la vez que estética y funcional. El tratamiento de ortodoncia con aparatología fija se ha relacionado con algunos aspectos que condicionan la calidad de vida, desde el punto de vista de la salud bucodental, como problemas en la higiene oral, mayor dificultad en la pronunciación, mayor riesgo de aparición de lesiones de caries o mayores restricciones alimentarias. Estos efectos adversos se han re…

The relationship between organizational interdependency and additionality obtained from innovation ecosystem participation

2019

Abstract Despite the increased interest in innovation ecosystems, few studies have assessed the extent to which the proclaimed benefits from participating in such ecosystems also occur, and under which circumstances they do occur. Uniting the literature on organizational interdependence and social exchange theory, we assess the behavioral and output additionality obtained by innovation ecosystem participants. In doing so, we build upon a sample of 473 innovative Finnish companies, of which 312 participated in an innovation ecosystem. We find a significantly positive relationship between organizational interdependence and output additionality, and find that this relationship is mediated by b…

Clinical and Functional Studies Reveal That TP73 Isoforms Levels Are Associated with Prognosis and RA-Resistance in Acute Promyelocytic Leukemia

2019

Background: TP73 isoforms gained particular relevance in acute promyelocytic leukemia (APL) since Bernasola et al (JEM. 2004) demonstrated that TAp73 was directly regulated by the PML protein in the nuclear body. The isoforms differ in their transcriptional activity, with those lacking domains in the N-terminal part of the protein exerting a dominant negative effect on TP73 function. In a retrospective analysis of patients with APL treated in ICAPL study, Lucena-Araujo et al (Blood 2015) demonstrated the association between higher ΔNp73/TAp73 ratio values and poor clinical outcome. However,there is a diversity of TP73 isoforms and specially those lacking N-terminal domains (e.g.ΔEx2p73, ΔEx…

Diagnosis of multiple sclerosis: a multicentre study to compare revised McDonald-2010 and Filippi-2010 criteria

2018

MRI has been formally included in the diagnostic work-up of patients with a suspicion of multiple sclerosis (MS) in 2001, to demonstrate disease dissemination in space (DIS) and time (DIT) and to exclude alternative diagnoses.1 Over time, these criteria have been modified to simplify their use and to clarify specific aspects (eg, spinal cord findings).2 One aspect marginally analysed in the diagnostic work-up of patients with clinically isolated syndrome (CIS) is the role of intracortical lesions (ICLs), which are a prominent feature of MS and contribute to disability and cognitive impairment.2 A single-centre study3 showed that inclusion of ICL for the evaluation of DIS in CIS increased th…

Poor estimates of motor variability are associated with longer grooved pegboard times for middle-aged and older adults

2018

Goal-directed movements that involve greater motor variability are performed with an increased risk that the intended goal will not be achieved. The ability to estimate motor variability during such actions varies across individuals and influences how people decide to move about their environment. The purpose of our study was to identify the decision-making strategies used by middle-aged and older adults when performing two goal-directed motor tasks and to determine if these strategies were associated with the time to complete the grooved pegboard test. Twenty-one middle-aged (48 ± 6 yr; range 40–59 yr, 15 women) and 20 older adults (73 ± 4 yr; range 65–79 yr, 8 women) performed two target…

Diversity of ankA and msp4 genes of Anaplasma phagocytophilum in Slovenia.

2015

Granulocytic anaplasmosis is a tick transmitted emerging disease in Europe and worldwide. The agent, Anaplasma phagocytophilum is transmitted by ticks of the genus Ixodes and causes infections in humans and domestic animals. The analysis of different target genes showed that in nature several genetic variants of A. phagocytophilum were present. The purpose of our study was to genetically characterize A. phagocytophilum strains from eight humans, 16 dogs, 12 wild boars, one bear and 18 tick pools from Slovenia. Therefore, the ankA and msp4 genes of A. phagocytophilum were chosen. The same genetic ankA and msp4 variant of A. phagocytophilum was detected in humans, wild boar and a part of the …

Multivariate analysis of the behavioral responses of rodents studied by means of different anxiety-inducing tests

Children’s Engagement with Mathematics in Kindergarten Mediated by the Use of Digital Tools

2013

The purpose of this chapter is to study children’s engagement with mathematics in kindergarten mediated by digital tools within the context of interactive whiteboard (IWB). Our study reports from a research project aiming at analysing in what ways digital tools may nurture children’s appropriation processes relative to mathematics. In adopting a sociocultural perspective on learning and development, observations together with video recordings have been analysed. Our study shows that the children make sense of the digital tools and are able to apply the tools purposefully due to the interaction with an adult within the zone of proximal development (ZPD). The children externalise their reason…

The Internet as a Pedagogical Tool in the Writing Process: A Research-Based Approach

2017

This article examines how the Internet can be used to ease the process of writing by suggesting resources for the planning, writing and revising stages and how they can be used to carry out a writing task. One such resource is the Blackboard platform, which serves as a discussion tool and for teacher-to-student and student-to-student feedback. Based on sound L2 writing theories and ICTs, a pedagogical proposal for a writing task is proposed and explained that involves invention and organizing techniques; peer and teacher evaluation using the Blackboard platform; activities to practice argumentative skills, the five-paragraph essay and paragraph structure and evaluation sheets with criteria …

Data mining, dashboards and statistics: a powerful framework for the chemical design of molecular nanomagnets

2021

Abstract Three decades of intensive research in molecular nanomagnets have brought the magnetic memory in molecules from liquid helium to liquid nitrogen temperature. The enhancement of this operational temperature relies on a wise choice of the magnetic ion and the coordination environment. However, serendipity, oversimplified theories and chemical intuition have played the main role. In order to establish a powerful framework for statistically driven chemical design, we collected chemical and physical data for lanthanide-based nanomagnets to create a catalogue of over 1400 published experiments, developed an interactive dashboard (SIMDAVIS) to visualise the dataset, and applied inferentia…