Search results for "CANDIDA"

showing 10 items of 844 documents

Detection of Candida albicans biofilm proteins induced by glucose, lactose, soy protein, and iron

2019

Background Oral candidiasis is one of the most common fungal infections, which attack the mucosa of the oral cavity. These lesions are mostly caused by the fungal species Candida albicans. Candida albicans is included in the normal oral microorganisms that are opportunistic pathogens, and its presence is quite large, which can reach 75% of the total oral fungal population. Research on specific proteins of Candida biofilm can be an alternative to early prevention of oral infections such as Oral Candidiasis. This biofilm protein can be used as a reference in making kits to detect the presence of microbes that cause infectious diseases. The purpose of this study was to determine molecular weig…

0303 health sciencesbiologyProtein band030306 microbiologyChemistryMicroorganismBiofilmExperimental laboratoryOral cavitybiology.organism_classification:CIENCIAS MÉDICAS [UNESCO]Microbiology03 medical and health scienceschemistry.chemical_compoundUNESCO::CIENCIAS MÉDICASLactoseCandida albicansGeneral DentistrySoy protein030304 developmental biology
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Evaluation of the antibacterial power and biocompatibility of zinc oxide nanorods decorated graphene nanoplatelets: New perspectives for antibiodeter…

2017

Background Nanotechnologies are currently revolutionizing the world around us, improving the quality of our lives thanks to a multitude of applications in several areas including the environmental preservation, with the biodeterioration phenomenon representing one of the major concerns. Results In this study, an innovative nanomaterial consisting of graphene nanoplatelets decorated by zinc oxide nanorods (ZNGs) was tested for the ability to inhibit two different pathogens belonging to bacterial genera frequently associated with nosocomial infections as well as biodeterioration phenomenon: the Gram-positive Staphylococcus aureus and the Gram-negative Pseudomonas aeruginosa. A time- and dose-…

3003Staphylococcus aureuslcsh:Medical technologyBiocompatibilitylcsh:Biotechnologyharmful to the environmentBiomedical EngineeringPharmaceutical ScienceMedicine (miscellaneous)Overall; ZNGs represent a promising candidate for developing biocompatible materials that can be exploitable in antimicrobial applications without releasing toxic compounds; harmful to the environment; Bioengineering; Medicine (miscellaneous); Molecular Medicine; Biomedical Engineering; Applied Microbiology and Biotechnology; 3003Biocompatible MaterialsBioengineeringNanotechnology02 engineering and technology010402 general chemistry01 natural sciencesApplied Microbiology and BiotechnologyNanomaterialsExtracellular polymeric substancelcsh:TP248.13-248.65HumansZNGs represent a promising candidate for developing biocompatible materials that can be exploitable in antimicrobial applications without releasing toxic compoundNanotubesbiologyChemistryResearchBiofilm021001 nanoscience & nanotechnologybiology.organism_classificationAntimicrobialAnti-Bacterial Agents0104 chemical scienceslcsh:R855-855.5NanotoxicologyBiofilmsPseudomonas aeruginosaZNGs; biodeterioration; antimicrobial nanomaterialMolecular MedicineGraphiteNanorodOverallZinc Oxide0210 nano-technologyBacteria
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"Table 6" of "Measurement of matter-antimatter differences in beauty baryon decays"

2017

Fig2b. The invariant mass distributions for $\Lambda^0_b\to \pi^- K^+ K^-$ decays. Uncertainties on the data points are statistical only and represent one standard deviations, calculated assuming Poisson-distributed entries.

8000.0Number of candidateNumber of candidatesP P --> LAMBDA/B0 X7000.0
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"Table 5" of "Measurement of matter-antimatter differences in beauty baryon decays"

2017

Fig2a. The invariant mass distributions for $\Lambda^0_b\to p\pi^-\pi^+\pi^-$ decays. Uncertainties on the data points are statistical only and represent one standard deviations, calculated assuming Poisson-distributed entries.

8000.0Number of candidatesNumber of candidateP P --> LAMBDA/B0 X7000.0
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La constitución del parlamento en caso de presuntas irregularidades electorales: Comentario a la stedh de 10 de julio de 2020 : Caso mugemangango c. …

2021

The ECHR analyzes, through this judgment, a claim based on the violation of the rights to free elections and to an effective remedy, the origin of which is found in a series of alleged electoral irregularities. The national body that had to resolve this issue was not impartial, and the complaint procedure lacked adequate and sufficient guarantees

:CIENCIAS JURÍDICAS [UNESCO]a claim based on the violation of the rights to free elections and to an effective remedycandidatoderecho a elecciones libres2070-8157 22082 Revista Boliviana de Derecho 565487 2021 31 7730074 La constitución del parlamento en caso de presuntas irregularidades electorales: Comentario a la stedh de 10 de julio de 2020 Caso mugemangango c. Bélgica Climent Gallartthe origin of which is found in a series of alleged electoral irregularities. The national body that had to resolve this issue was not impartialJorge Antonio The ECHR analyzesComentario a la stedh de 10 de julio de 2020 Caso mugemangango c. Bélgica Climent Gallart [2070-8157 22082 Revista Boliviana de Derecho 565487 2021 31 7730074 La constitución del parlamento en caso de presuntas irregularidades electorales]ParliamentdiputadoMember of Parliament. 662 673UNESCO::CIENCIAS JURÍDICASthrough this judgmentand the complaint procedure lacked adequate and sufficient guarantees Parlamentoright to free electionscandidate
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Intra-abdominal

2016

Aims To evaluate the contribution of light microscopy to detecting Candida spp infection in patients with complicated intra-abdominal infections (IAIs) admitted for acute abdomen to a quality assurance (QA)-certified surgical emergency ward. Methods We conducted a retrospective study (2008–2012) of 809 abdominal intraoperative or biopsy tissue specimens obtained from patients admitted with acute abdomen and microbiological samples positive for Candida spp. Demographic data, mortality, comorbidities, specimen type, microscopy results, special histological staining performed, antimicrobial therapy were collected and analysed. Any comments at the multidisciplinary team meeting was recorded in …

Abdomen AcuteAdultAged 80 and overMaleMicroscopyAntifungal AgentsQuality Assurance Health CareCandidiasisFUNGIMiddle AgedGASTROENTEROLOGYEchinocandinsYoung AdultINFECTIONSHumansINFECTIOUS INTESTINAL DISEASEFemaleOriginal Article1506FluconazoleAgedCandidaRetrospective StudiesJournal of clinical pathology
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Multiple endocrine neoplasia type 1 gene expression is normal in sporadic adrenocortical tumors.

2000

Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder with neoplasia of the anterior pituitary, the parathyroid, the endocrine pancreas and other endocrine tissues including the adrenal cortex. The tumor-suppressor gene causing this disease was identified at the gene locus 11q13. We recently reported that adrenocortical carcinomas frequently show loss of heterozygosity (LOH) of 11q13, but do not contain point mutations within the MEN1-coding region. To investigate whether reduced gene expression (for example by mutations within the MEN1 promoter) may contribute to the tumorigenesis of sporadic adrenocortical tumors, 24 adrenocortical specimen were studied by Northern …

Adenomamedicine.medical_specialtyCandidate geneendocrine system diseasesHydrocortisoneEndocrinology Diabetes and MetabolismGene ExpressionLoss of HeterozygosityBiologyLoss of heterozygosityEndocrinologyReference ValuesInternal medicineGene expressionAdrenal GlandsmedicineMultiple Endocrine Neoplasia Type 1Adrenocortical carcinomaHumansMEN1Northern blotRNA MessengerMultiple endocrine neoplasiaAldosteroneAdrenal cortexCarcinomaGeneral Medicinemedicine.diseaseAdrenal Cortex Neoplasmsmedicine.anatomical_structureEndocrinologyCancer researchEuropean journal of endocrinology
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Comparative genetic study of intratumoral heterogenous MYCN amplified neuroblastoma versus aggressive genetic profile neuroblastic tumors.

2016

Intratumoral heterogeneous MYCN amplification (hetMNA) is an unusual event in neuroblastoma with unascertained biological and clinical implications. Diagnosis is based on the detection of MYCN amplification surrounded by non-amplified tumor cells by fluorescence in situ hybridization (FISH). To better define the genetic features of hetMNA tumors, we studied the Spanish cohort of neuroblastic tumors by FISH and single nucleotide polymorphism arrays. We compared hetMNA tumors with homogeneous MNA (homMNA) and nonMNA tumors with 11q deletion (nonMNA w11q-). Of 1091 primary tumors, 28 were hetMNA by FISH. Intratumoral heterogeneity of 1p, 2p, 11q and 17q was closely associated with hetMNA tumor…

Adult0301 basic medicineCancer ResearchCandidate geneAdolescentGene DosageSingle-nucleotide polymorphismBiologyPolymorphism Single NucleotideGene dosageGenetic profileCohort StudiesNeuroblastomaYoung Adult03 medical and health sciences0302 clinical medicineNeuroblastomaGeneticsmedicineHumansChildMolecular BiologyIn Situ Hybridization FluorescenceAgedAged 80 and overOncogene ProteinsGeneticsN-Myc Proto-Oncogene Proteinmedicine.diagnostic_testChromosomes Human Pair 11Nuclear ProteinsChromosomeMiddle Agedmedicine.diseaseNeuroblastic Tumor030104 developmental biologyChromosomes Human Pair 1Child PreschoolChromosomes Human Pair 2030220 oncology & carcinogenesisCancer researchChromosome DeletionChromosomes Human Pair 17Fluorescence in situ hybridization
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Homozygous familial hypercholesterolemia in Italy: Clinical and molecular features

2020

Abstract Background and aims Homozygous familial hypercholesterolemia (HoFH) is a rare genetic disorder characterized by extremely elevated plasma levels of low density lipoprotein cholesterol (LDL-C) and high risk of premature atherosclerotic cardiovascular disease (ASCVD). HoFH is caused by pathogenic variants in several genes, such as LDLR, APOB and PCSK9, responsible for autosomal dominant hypercholesterolemia (ADH), and LDLRAP1 responsible for autosomal recessive hypercholesterolemia (ARH). Aim of this study was the review of the clinical and molecular features of patients with HoFH identified in Italy from 1989 to 2019. Methods Data were collected from lipid clinics and laboratories, …

Adult0301 basic medicinemedicine.medical_specialtyCandidate geneCandidate geneGenotype-phenotype correlationApolipoprotein BCandidate genes; Genotype-phenotype correlations; Homozygous familial hypercholesterolemia; Pathogenic variantsHomozygous familial hypercholesterolemiaGenotype-phenotype correlationsFamilial hypercholesterolemia030204 cardiovascular system & hematologyCompound heterozygosityCandidate genesHyperlipoproteinemia Type II03 medical and health sciences0302 clinical medicineInternal medicinemedicineHumansbiologybusiness.industryPCSK9HomozygoteGenetic disorderPathogenic variantsCandidate genes; Genotype-phenotype correlations; Homozygous familial hypercholesterolemia; Pathogenic variants;medicine.diseasePhenotype030104 developmental biologyEndocrinologyItalyReceptors LDLAutosomal Recessive HypercholesterolemiaMutationLDL receptorbiology.proteinlipids (amino acids peptides and proteins)Proprotein Convertase 9Cardiology and Cardiovascular Medicinebusiness
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Performance of existing clinical scores and laboratory tests for the diagnosis of invasive candidiasis in critically ill, nonneutropenic, adult patie…

2022

Background The Fungal Infections Definitions in Intensive Care Unit (ICU) patients (FUNDICU) project aims to provide standard sets of definitions for invasive fungal diseases in critically ill, adult patients. Objectives To summarize the available evidence on the diagnostic performance of clinical scores and laboratory tests for invasive candidiasis (IC) in nonneutropenic, adult critically ill patients. Methods A systematic review was performed to evaluate studies assessing the diagnostic performance for IC of clinical scores and/or laboratory tests vs. a reference standard or a reference definition in critically ill, nonneutropenic, adult patients in ICU. Results Clinical scores, despite t…

AdultAntifungal AgentsCritical CarediagnosisCritical IllnesscandidemiaDermatologyGeneral Medicineinvasive candidiasisIC.Intensive Care UnitsInfectious DiseasesCandida; biomarker; candidaemia; deep-seated candidiasis; diagnosis; invasive candidiasisHumansbiomarkercandidaemiaCandidiasis InvasiveProspective Studiesdeep-seated candidiasisCandida
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