Search results for "Child health."
showing 10 items of 1822 documents
Asphyxia Activates P65 and Induces VEGF-A Gene Expression in Retina and Choroid from Newborn Piglets
2011
Objective: Exposure to lower oxygen causes oxidative stress and promotes angiogenesis. Asphyctic neonates have shown higher cord-blood vascular endothelial growth factor (VEGF). We hypothesized that retina and choroid having a different circulatory regulation (choroid lacks vascular auto-regulation) would acutely stimulate angiogenesis in response to short and severe hypoxemia.
Evaluación de los aspectos formales de las revistas pediátricas españolas
2007
Introducción: La normalización de las revistas científicas es impresscindible para la transmisión correcta del conocimiento, pues garantiza la universalidad y reproducibilidad de las investigaciones. El objetivo de este trabajo es realizar una evaluación de los aspectos formales de las revistas pediátricas españolas. Material y métodos: En el año 2005 se estudiaron las características formales de las revistas pediátricas españolas, en particular, y de las revistas biomédicas españolas, en general. Se implementó un formulario, utilizado para la selección de las revistas que forman parte de la cobertura de la base de datos del Índice Médico Español (IME), que evaluaba 64 características difer…
A Multicultural Demographic Study to Evaluate the Impact of the SARS-CoV-2 Pandemic on the Job Satisfaction across the Dental Industry
2021
ABSTRACT Objective: To evaluate the difference in working conditions as perceived by dentists during the pandemic and their professional satisfaction levels. Material and Methods: An online survey was conducted using the convenience and snowball sampling methods. Two hundred seventy-two respondents across various countries answered information related to socio-demographic data and work satisfaction levels during the SARS-CoV-2 pandemic. Results: 40.1% of dentists reported dissatisfied with their current work, while another 13.6% of dentists fell in the extremely dissatisfied category. 22.8% of dentists were significantly dissatisfied with their current income. Furthermore, 38.4% of the dent…
Auditory, speech and language development in young children with cochlear implants compared with children with normal hearing.
2010
Abstract Objective This study had two aims: (1) to document the auditory and lexical development of children who are deaf and received the first cochlear implant (CI) by the age of 16 months and the second CI by the age of 31 months and (2) to compare these children's results with those of children with normal hearing (NH). Methods This longitudinal study included five children with NH and five with sensorineural deafness. All children of the second group were observed for 36 months after the first fitting of the device (cochlear implant). The auditory development of the CI group was documented every 3 months up to the age of two years in hearing age and chronological age and for the NH gro…
Safety, tolerability, pharmacokinetics, pharmacodynamics, and exploratory efficacy of the novel enzyme replacement therapy avalglucosidase alfa (neoG…
2019
This multicenter/multinational, open-label, ascending-dose study (NCT01898364) evaluated safety, tolerability, pharmacokinetics, pharmacodynamics, and exploratory efficacy of repeat-dose avalglucosidase alfa (neoGAA), a second-generation, recombinant acid α-glucosidase replacement therapy, in late-onset Pompe disease (LOPD). Patients ≥18 years, alglucosidase alfa naïve (Naïve) or previously receiving alglucosidase alfa for ≥9 months (Switch), with baseline FVC ≥50% predicted and independently ambulatory, received every-other-week avalglucosidase alfa 5, 10, or 20 mg/kg over 24 weeks. 9/10 Naïve and 12/14 Switch patients completed the study. Avalglucosidase alfa was well-tolerated; no deaths…
Effects of dopamine infusion on plasma catecholamines in preterm and term newborn infants.
1991
Newborn infants (21 preterm and 13 term) received dopamine infusions at a low (2.5-3.4 micrograms/kg per min) and/or high (5-10 micrograms/kg per min) infusion rate and changes in plasma catecholamines were monitored. The mean baseline values for dopamine, noradrenaline and adrenaline were between 240 and 560, 125 and 144 and 62 and 82 pg/ml, respectively. During low-rate infusion of dopamine, there was a significant increase in plasma dopamine (20-100 fold), noradrenaline (three- to five-fold) and adrenaline (threefold). Administration of dopamine at the high rate resulted in an even larger increase in the plasma catecholamines (dopamine, 100-300 fold; noradrenaline, seven- to eightfold; a…
Análisis de la productividad e impacto científico de la pediatría española (2006-2010)
2013
Resumen: Introducción: El objetivo de este trabajo es cuantificar mediante indicadores bibliométricos la productividad científica de los investigadores e instituciones españolas que publican en revistas pediátricas nacionales y extranjeras, y en revistas multidisciplinares o de otras disciplinas o áreas del conocimiento, durante el quinquenio 2006-2010, así como determinar su repercusión o impacto. Método: Los trabajos objeto de estudio se han obtenido de las bases de datos Science Citation Index Expanded, Scopus, Índice Médico Español e Índice Bibliográfico Español en Ciencias de la Salud, aplicando perfiles de búsqueda específicos. Resultados: Se publicaron 7.971 artículos en 971 revistas…
Array CGH defined interstitial deletion on chromosome 14: a new case
2009
Interstitial deletions of the long arm of chromosome 14 are relatively rare. We report a 8.5-year-old girl with dysmorphic facial features and mental retardation associated with a de novo interstitial deletion of chromosome 14. The comparison between our patient and all published patients is reviewed. The genetic investigations have allowed us to define the critical chromosomal region and to start an accurate follow-up.
Small omphalocele with umbilical evagination of the bladder: a distinct entity?
2006
A neonatal case of umbilical evagination of the bladder combined with a small omphalocele is presented. This rare congenital malformation has previously been described in only three cases. Umbilical evagination can be understood as a disturbance of development of both the vitelline and allantoic ducts, resulting in a non-descended but otherwise normal bladder opening to the inferior margin of a small omphalocele. Diagnosis is made by clinical inspection and ultrasound. Since other malformations are not present, this entity may be regarded as a minor form of a lower midline defect with excellent prognosis.
Short Sleep Duration Is Related to Emerging Cardiovascular Risk Factors in Obese Children
2015
Objective: The aim of the present study was to evaluate the influence of sleep duration on cardiovascular risk factors in obese children. Methods: Cross-sectional analysis of 90 obese children ages 7 to 16 years. Anthropometric and clinical evaluation with specification of dietary and lifestyle habits was carried out during an office visit. Sleep duration was evaluated by the BEARS (B = bedtime issues, E = excessive daytime sleepiness, A = night awakening, R = regularity and duration of sleep, S = snoring) questionnaire on children's sleep characteristics. Sleep time adequacy by age was assessed according to the criteria of the National Sleep Foundation. Biochemical blood variables indicati…