Search results for "Circulator"

showing 10 items of 702 documents

Aggravated Atherosclerosis and Vascular Inflammation With Reduced Kidney Function Depend on Interleukin-17 Receptor A and Are Normalized by Inhibitio…

2018

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0301 basic medicinemedicine.medical_specialtylcsh:Diseases of the circulatory (Cardiovascular) systemIl17ra interleukin-17 receptor A (gene name)medicine.medical_treatmentInterleukin-17 receptormacrophage030204 cardiovascular system & hematologyLesionPRECLINICAL RESEARCH03 medical and health sciencesPCR polymerase chain reaction0302 clinical medicineInternal medicinemedicineMacrophageReceptorbusiness.industryCKD chronic kidney diseaseLDLr low-density lipoprotein receptorIL interleukinBlockadeEndothelial stem cell030104 developmental biologyEndocrinologyCytokinelcsh:RC666-701Interleukin 17medicine.symptomatherosclerosisCardiology and Cardiovascular Medicinebusinessinterleukin 17chronic kidney diseaseJACC: Basic to Translational Science
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Development and Validation of a New Clinical Prediction Model of Catheter-Related Thrombosis Based on Vascular Ultrasound Diagnosis in Cancer Patients

2020

Background: Central venous catheters are convenient for drug delivery and improved comfort for cancer patients, but they also cause serious complications. The most common complication is catheter-related thrombosis (CRT). Objectives: This study aimed to evaluate the incidence and risk factors for CRT in cancer patients and develop an effective prediction model for CRT in cancer patients. Methods: The development of our prediction model was based on a retrospective cohort (n = 3,131) from the National Cancer Center. Our prediction model was confirmed in a prospective cohort from the National Cancer Center (n = 685) and a retrospective cohort from the Hunan Cancer Hospital (n = 61). The predi…

0301 basic medicinemedicine.medical_specialtylcsh:Diseases of the circulatory (Cardiovascular) systemMultivariate analysis030204 cardiovascular system & hematologyCardiovascular Medicinecathetersnomogram03 medical and health sciences0302 clinical medicineInternal medicinemedicinecancerRisk factorProspective cohort studythrombosisOriginal ResearchReceiver operating characteristicbusiness.industryCancerRetrospective cohort studyNomogrammedicine.disease030104 developmental biologyrisk factorlcsh:RC666-701CohortCardiology and Cardiovascular MedicinebusinessFrontiers in Cardiovascular Medicine
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"Table 2" of "Measurement of the inclusive jet cross-section in p anti-p collisions at s**(1/2) =1.96-TeV"

1970

Measured inclusive jet cross section as a function of jet transverse momentum for absolute values of the jet rapidity from 0.4 to 0.8 for cone radius R = 0.7.

20477612047761Astrophysics::High Energy Astrophysical PhenomenaRapidity DependencePBAR P --> JET XAstrophysics::Cosmology and Extragalactic AstrophysicsJet Productionrespiratory systemequipment and suppliescomplex mixturesInclusiveHigh Energy Physics::ExperimentD2SIG/DPT/DYRAPTransverse Momentum Dependencehuman activitiesDouble Differential Cross Sectioncirculatory and respiratory physiology
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"Table 6" of "Measurement of the inclusive jet cross-section in p anti-p collisions at s**(1/2) =1.96-TeV"

1970

Measured inclusive jet cross section as a function of jet transverse momentum for absolute values of the jet rapidity from 2.0 to 2.4 for cone radius R = 0.7.

20477612047761Astrophysics::High Energy Astrophysical PhenomenaRapidity DependencePBAR P --> JET XJet Productionrespiratory systemequipment and suppliescomplex mixturesInclusiveHigh Energy Physics::ExperimentD2SIG/DPT/DYRAPTransverse Momentum Dependencehuman activitiesDouble Differential Cross Sectioncirculatory and respiratory physiology
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Valor pronóstico de la resonancia magnética cardiaca tras un infarto agudo de miocardio con elevación del segmento ST

2011

INTRODUCCIÓN Las enfermedades cardiovasculares, y en concreto el infarto agudo de miocardio con elevación de ST (IAMEST) son una importante causa de mortalidad en los países desarrollados. La resonancia magnética cardiaca (RMC) es una técnica cada vez más usada tras un IAMEST, permite un análisis simultáneo y fiable de varios índices cardiacos, que han demostrado valor para predecir la recuperación de la función sistólica. No obstante, los datos sobre su valor pronóstico son escasos y no hay estudios que realicen un análisis exhaustivo de todos los índices. Esta información es imprescindible para que la RMC se incorpore definitivamente a nuestra práctica clínica habitual. OBJETIVOS - Valora…

61MedicinaPatologia del sistema circulatori dels vasos sanguinis. Trastorns cardiovasculars616.1
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Influencia de la diabetes experimental sobre la reactividad de las arterias carótida y renal de conejo al péptido atrial natriurético : mecanismos im…

2013

La diabetes está asociada a una mayor prevalencia de hipertensión, ictus, enfermedades cardiovasculares y nefropatía. El péptido atrial natriurético (ANP) juega un papel importante en la fisiopatología cardiovascular y podría tener acciones protectoras cardiovasculares y nefrovasculares en pacientes diabéticos. En este trabajo hemos estudiado las modificaciones producidas por la diabetes en los mecanismos que regulan la respuesta de las arterias carótida y renal de conejo al ANP. La concentración plasmática de ANP en conejos diabéticos fue mayor que en conejos control. ARTERIA CARÓTIDA. El ANP indujo una relajación de la arteria carótida, que fue menor en conejo diabético que en conejo cont…

:CIENCIAS MÉDICAS ::Patología::Patología cardiovascular [UNESCO]:CIENCIAS MÉDICAS ::Patología::Patología experimental [UNESCO]diabetesUNESCO::CIENCIAS MÉDICAS ::Patología::Patología experimentalUNESCO::CIENCIAS MÉDICAS ::Patología::Patología cardiovascularcanales de potasioarteria carótidapéptido atrial natriuréticocardiovascular systemarteria renalprostanoidesendoteliohormones hormone substitutes and hormone antagonistscirculatory and respiratory physiology
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A Difficult Case of Necrotizing Fasciitis Caused By Acinetobacter baumannii

2010

This study reports the case of a 55-year-old woman with diabetes with a necrotizing fasciitis of the right lower limb and the perineum, first admitted at the emergency department for septic shock with cardiac arrest, and later transferred to the department of surgery. Microbiological and histopathological examination confirmed the diagnosis of necrotizing fasciitis caused by Acinetobacter baumanii. A broad-spectrum antibiotic therapy was administered and later readjusted according to the results of microbiological culture. Intensive hemodynamic support was required. Wounds were dressed daily with a 3 percent boric acid solution and a silver sulfadiazine-impregnated dressing. An extensive s…

Acinetobacter baumanniiInsecticidesmedicine.medical_specialtyMicrobiological culturemedicine.medical_treatmentAcinetobacter Infections/diagnosis Acinetobacter Infections/drug therapy Acinetobacter Infections/microbiology* Acinetobacter baumannii/isolation &ampSettore MED/19 - Chirurgia PlasticaBoric AcidsmedicineHumansFasciitis NecrotizingFasciitisDebridementbiologybusiness.industrySeptic shockSoft Tissue Infectionspurification* Anti-Infective Agents Local/therapeutic use Boric Acids/therapeutic use Debridement Fasciitis Necrotizing/diagnosis Fasciitis Necrotizing/drug therapy Fasciitis Necrotizing/microbiology* Female Heart Arrest Humans Insecticides/therapeutic use Middle Aged Pseudomonas aeruginosa/isolation &ampGeneral MedicineEmergency departmentMiddle Agedbiology.organism_classificationmedicine.diseaseShock SepticSilver SulfadiazineHeart ArrestSurgeryAcinetobacter baumanniiPerineummedicine.anatomical_structureDebridementShock (circulatory)Pseudomonas aeruginosapurification Shock Septic Silver Sulfadiazine/therapeutic use Soft Tissue Infections/diagnosis Soft Tissue Infections/drug therapy Soft Tissue Infections/microbiologyAnti-Infective Agents LocalFemaleSurgerymedicine.symptombusinessAcinetobacter InfectionsThe International Journal of Lower Extremity Wounds
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Epithelial contribution to the profibrotic stiff microenvironment and myofibroblast population in lung fibrosis

2017

The contribution of epithelial-to-mesenchymal transition (EMT) to the profibrotic stiff microenvironment and myofibroblast accumulation in pulmonary fibrosis remains unclear. We examined EMT-competent lung epithelial cells and lung fibroblasts from control (fibrosisfree) donors or patients with idiopathic pulmonary fibrosis (IPF), which is a very aggressive fibrotic disorder. Cells were cultured on profibrotic conditions including stiff substrata and TGF-β1, and analyzed in terms of morphology, stiffness, and expression of EMT/myofibroblast markers and fibrillar collagens. All fibroblasts acquired a robust myofibroblast phenotype on TGF-β1 stimulation. Yet IPF myofibroblasts exhibited highe…

Adult0301 basic medicineEpithelial-Mesenchymal TransitionPulmonary FibrosisPopulationmacromolecular substancesEpithelial cellsBiologyEpitheliumPulmonary fibrosisTransforming Growth Factor beta103 medical and health sciencesIdiopathic pulmonary fibrosisMechanobiology0302 clinical medicinePulmonary fibrosismedicineHumansMyofibroblastsFibroblasteducationLungMolecular BiologyCells Culturededucation.field_of_studyCèl·lules epitelialsLungEpithelial CellsFibrosi pulmonarArticlesCell BiologyFibroblastsmusculoskeletal systemmedicine.diseasePhenotype030104 developmental biologymedicine.anatomical_structureCellular MicroenvironmentCell Biology of DiseaseCase-Control Studies030220 oncology & carcinogenesisembryonic structurescardiovascular systemCancer researchMyofibroblastcirculatory and respiratory physiology
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Clinical profiles and quality of care of subjects with type 2 diabetes according to their cardiovascular risk: an observational, retrospective study

2021

Abstract Background The European Society of Cardiology (ESC) recently defined cardiovascular risk classes for subjects with diabetes. Aim of this study was to explore the distribution of subjects with type 2 diabetes (T2D) by cardiovascular risk groups according to the ESC classification and to describe the quality indicators of care, with particular regard to cardiovascular risk factors. Methods The study is based on data extracted from electronic medical records of patients treated at the 258 Italian diabetes centers participating in the AMD Annals initiative. Patients with T2D were stratified by cardiovascular risk. General descriptive indicators, measures of intermediate outcomes, inten…

AdultBlood GlucoseMalelcsh:Diseases of the circulatory (Cardiovascular) systemmedicine.medical_specialtyTime FactorsEndocrinology Diabetes and MetabolismType 2 diabetesIncretinsRisk AssessmentDiabetes mellitusInternal medicinemedicineElectronic Health RecordsHumansHypoglycemic AgentsMedical prescriptionSodium-Glucose Transporter 2 InhibitorsOriginal InvestigationAgedQuality Indicators Health CareRetrospective StudiesAngiologyCardiovascular risk Humans Hypoglycemic Agents Incretins Italy Male Middle Aged Retrospective Studies Risk Assessment Sodium-Glucose Transporter 2 Inhibitors Time Factors Treatment Outcome Quality Indicators Health Care Quality of care Type 2 diabetes Adult Aged Aged 80 and over Biomarkers Blood Glucose Cardiovascular Diseases Diabetes Mellitus Type 2 Dipeptidyl-Peptidase IV Inhibitors Heart Disease Risk Factors Female Electronic Health RecordsAged 80 and overDipeptidyl-Peptidase IV Inhibitorsbusiness.industryMedical recordQuality of careType 2 diabetesRetrospective cohort studyMiddle AgedCardiovascular riskmedicine.diseaseTreatment OutcomeDiabetes Mellitus Type 2ItalyCardiovascular DiseasesHeart Disease Risk Factorslcsh:RC666-701AlbuminuriaFemaleObservational studymedicine.symptomCardiology and Cardiovascular MedicinebusinessBiomarkersCardiovascular Diabetology
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ABNORMALLY HIGH THROMBOXANE BIOSYNTHESIS IN HOMOZYGOUS HOMOCYSTINURIA. EVIDENCE FOR PLATELET INVOLVEMENT AND PROBUCOL-SENSITIVE MECHANISM.

1993

Homocystinuria due to homozygous cystathionine beta-synthase deficiency is an inborn error of metabolism characterized by a high incidence of thrombosis and premature atherosclerosis. We evaluated TXA2 biosynthesis in vivo and several in vitro tests of platelet function in 11 homocystinuric patients and 12 healthy controls. In vitro, patients' platelet aggregation was within control values as were TXB2 formation, fibrinogen binding, and ATP secretion in response to thrombin. In contrast, the urinary excretion of 11-dehydro-TXB2, a major enzymatic derivative of TXA2, was > 2 SD of controls in all patients (1,724 +/- 828 pg/mg creatinine, mean +/- SD, in patients vs. 345 +/- 136 in controls, …

AdultBlood PlateletsMalemedicine.medical_specialtyAdolescentPlatelet AggregationThromboxaneProbucolHomocystinuriaInternal medicinemedicineHumansPlateletPlatelet activationChildBlood CoagulationbiologyAspirinChemistryFibrinolysisHomozygoteFibrinogen bindingThromboxanesGeneral Medicinemedicine.diseaseCystathionine beta synthaseEndocrinologyProbucolbiology.proteinlipids (amino acids peptides and proteins)FemaleHomocystinuriaCyclooxygenasemedicine.drugcirculatory and respiratory physiologyResearch Article
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