Search results for "ETIOLOGY"

showing 10 items of 639 documents

Association of mechanical bowel preparation with oral antibiotics and anastomotic leak following left sided colorectal resection: an international, m…

2018

INTRODUCTION: The optimal bowel preparation strategy to minimise the risk of anastomotic leak is yet to be determined. This study aimed to determine whether oral antibiotics combined with mechanical bowel preparation (MBP+Abx) was associated with a reduced risk of anastomotic leak when compared to mechanical bowel preparation alone (MBP) or no bowel preparation (NBP).METHODS: A pre-planned analysis of the European Society of Coloproctology (ESCP) 2017 Left Sided Colorectal Resection audit was performed. Patients undergoing elective left sided colonic or rectal resection with primary anastomosis between 1 January 2017 and 15 March 2017 by any operative approach were included. The primary out…

Laparoscopic surgeryMaleLeakmedicine.medical_specialtyCathartics/administration & dosagemedicine.drug_classmedicine.medical_treatmentAntibioticsanastomotic leakanastomotic leak; bowel preparation; colonic cancer; Colorectal surgery; laparoscopic surgery; Gastroenterology030230 surgeryAnastomosisPreoperative Care/methodsNO03 medical and health sciences0302 clinical medicineColorectal surgeryAnti-Bacterial Agents/administration & dosagePreoperative CareMedicineHumansrisk factorsProspective StudiesMulti centreProspective cohort studyColectomyAgedta3126Medical Auditbusiness.industryCatharticsdigestive oral and skin physiologyGastroenterologycolonic cancerMiddle Agedlaparoscopic surgeryColorectal surgerydigestive system diseasesSurgeryAnti-Bacterial Agents030220 oncology & carcinogenesisBowel preparationbowel preparationDrug Therapy CombinationFemaleColectomy/adverse effectsbusinessAnastomotic Leak/etiology
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Italian multicentric survey on laparoscopic spleen surgery in the pediatric population.

2007

Abstract Background: Some technical aspects of laparoscopic spleen surgery still are debated, although efforts have been made to standardize them. The position of the patient, the approach to the spleen, vessel identification and division, and spleen extraction can vary from center to center. Methods: This retrospective muticentric study led by the Societa` Italiana di Videochirurgia Infantile (SIVI) examined indications, surgical details, and complications of laparoscopic spleen surgery in the pediatric population during a 5-year period. Results: The study period from January 1999 to December 2003 (5 years) involved nine centers and included 85 patients with a mean age of 10 years (range, …

Laparoscopic surgeryMalemedicine.medical_specialtyAdolescentmedicine.medical_treatmentSplenectomySpleenAdolescent Age Distribution Child Child; Preschool Data Collection Female Hematologic Diseases; complications/diagnosis Humans Incidence Intraoperative Complications; diagnosis/epidemiology Italy Laparoscopy; adverse effects/methods Male Pediatrics; methods Postoperative Complications; diagnosis/epidemiology Prognosis Retrospective Studies Risk Assessment Severity of Illness Index Sex Distribution Splenectomy; adverse effects/methods Splenic Diseases; diagnosis/etiology/surgery Survival AnalysisPediatricsRisk AssessmentSeverity of Illness IndexmethodsAge DistributionPostoperative ComplicationsmedicineHumansSex DistributionLaparoscopyChildPreschoolIntraoperative ComplicationsRetrospective StudiesSplenic Diseasesadverse effects/methodsmedicine.diagnostic_testdiagnosis/epidemiologybusiness.industryData CollectionIncidenceComplications — Fenestration — Laparoscopic splenectomy — Multicentric survey — Spleen —technical detailscomplications/diagnosismedicine.diseasePrognosisdiagnosis/etiology/surgeryHematologic DiseasesSurvival AnalysisEndoscopySurgerymedicine.anatomical_structureItalyChild PreschoolSplenectomySurgeryFemaleLaparoscopySplenic diseasebusinessComplicationAbdominal surgery
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Human Papillomavirus Infection: A Risk Factor for Oral and Oropharyngeal Cancers

2020

A wide range of human papillomavirus (HPV) prevalence data is now available for head and neck squamous cell carcinomas (HNSCCs), especially for those cancers originating from the epithelial lining of the upper aero-digestive tract (UADT) (i.e., the pharynx, the larynx, and the oral cavity). There is strong evidence that supports HPV as an etiological cause of head and neck carcinogenesis particularly for distinct oropharyngeal subsites. A specific molecular, histopathological, clinical, and prognostic profile is intimately connected with HPV infection. While the role of HPV in oropharyngeal carcinogenesis is firmly acknowledged, its role in oral cancer is currently being debated. Several re…

LarynxOncologymedicine.medical_specialtybusiness.industryPharynxHPV infectionvirus diseasesCancermedicine.disease_causemedicine.diseasemedicine.anatomical_structureSettore MED/28 - Malattie OdontostomatologicheInternal medicineHPV oral cancer oropharyngeal cancermedicineEtiologyRisk factorCarcinogenesisbusinessOropharyngeal Cancers
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Zobu sakņu rezorbcija: Literatūras un gadījuma apskats

2020

Biežāk netīša gadījuma atradne - saknes rezorbcija (iekšēja vai ārēja) - ir asociēta ar zobu audu, kā arī ar alveolārā kaula lokālu zudumu sakarā ar pastiprinātu osteoklastu funkciju darbību. Visbiežāk asimptomātisku procesu novēro kā patoloģisku procesu patstāvīgā zoba audos vai arī fizioloģisku procesu maiņas sakodienā. Šī gadījuma analīze ietver literatūras apskatu par saknes rezorbcijas etioloģiju, riska un predisponējošiem faktoriem, diagnozes uzstādīšanu un klasifikāciju, kā arī ārstēšanu. Gadījuma analīze: Perforējoša zoba saknes kakliņa daļas rezorbcija.

Literature reviewTooth Root resorptionCase reportAetiologyPathophysiologyMedicīna
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Serum ferritin is a discriminant marker for both fibrosis and inflammation in histologically proven non-alcoholic fatty liver disease patients

2011

INTRODUCTION: Differentiation between steatosis and non-alcoholic steatohepatitis (NASH) in non-alcoholic fatty liver disease (NAFLD) is important as NASH progress to cirrhosis. No specific laboratory/imaging technique exists either to diagnose NASH or to select patients for liver biopsy. PATIENTS AND METHODS: We evaluated serum ferritin and the features of metabolic syndrome with respect to histological inflammation and/or fibrosis in NAFLD patients. The Kleiner scoring system was used to classify NAFLD in consecutive liver biopsies. One hundred and eleven patients: median age 52.6, 64 males, obesity 62, diabetes mellitus (DM) 58, arterial hypertension 26 and hyperlipidaemia 40%. RESULTS: …

Liver CirrhosisAdultMaleBiopsyHyperlipidemiasFatty Liver/blood/diagnosis/etiology/pathologyRisk AssessmentSeverity of Illness IndexHepatitisBody Mass IndexDiabetes ComplicationsYoung AdultNon-alcoholic Fatty Liver DiseasePredictive Value of TestsRisk FactorsNAFLDLondonMetabolic Syndrome X/blood/*complicationsHumansAspartate AminotransferasesObesityBiological Markers/bloodliver fibrosisAgedMetabolic SyndromeInflammationFerritinChi-Square DistributionPatient SelectionNASHHepatitis/blood/complications/*diagnosisMiddle AgedFibrosisFatty LiverLiver Cirrhosis/blood/*diagnosis/etiologyNomogramsLogistic ModelsHyperlipidemias/blood/complicationsHypertension/blood/complicationsFerritinsHypertensionFerritin; Fibrosis; Inflammation; NAFLD; NASHAspartate Aminotransferases/bloodFemaleDiabetes Complications/blood/diagnosis/etiologyObesity/complicationsBiomarkersFerritins/*blood
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Lack of correlation between serum anti-HBcore detectability and hepatocellular carcinoma in patients with HCV-related cirrhosis

2008

BACKGROUND: While the likelihood of developing hepatocellular carcinoma (HCC) in patients coinfected with both HBV and HCV is increased, the role of previous exposure to HBV as a risk factor associated with tumor occurrence in subjects with HCV-related cirrhosis has not been fully investigated. AIM: To assess whether serum anti-HBc positivity, as a marker of previous HBV exposure, is associated with HCC development in HCV-related positive, hepatitis B surface antigen (HBsAg) negative patients with cirrhosis treated with alfa-interferon (IFN) monotherapy. PATIENTS AND: A database including 883 consecutive patients (557 men, mean age 54.7 yr) with histologically METHODS: proven cirrhosis trea…

Liver CirrhosisMalePathologyCirrhosisAdult Antibodies; Viral; blood Carcinoma; Hepatocellular; blood/pathology/virology Cohort Studies Female Hepatitis B Core Antigens; immunology Hepatitis B virus; immunology Hepatitis C; blood/complications/pathology Humans Liver Cirrhosis; blood/etiology/pathology Liver Neoplasms; blood/pathology/virology Male Middle Aged Retrospective Studies Risk FactorsAntibodies ViralGastroenterologyanti HBcCohort StudiesimmunologyRisk FactorsHBVViralHCCCIRRHOSISLiver NeoplasmsGastroenterologyvirus diseasesHBV HCV COINFECTIONMiddle AgedHepatitis B Core AntigensHepatitis CAdult; Antibodies Viral; Carcinoma Hepatocellular; Cohort Studies; Female; Hepatitis B Core Antigens; Hepatitis B virus; Hepatitis C; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Retrospective Studies; Risk Factors; GastroenterologyHepatocellular carcinomaHCVFemaleAdultmedicine.medical_specialtyHepatitis B virusCarcinoma Hepatocellularblood/pathology/virologyAntibodiesbloodblood/complications/pathologyInternal medicinemedicineHumansIn patientHEPATOCELLULAR CARCINOMAHEPATOCELLULAR CARCINOMA; HCV; HBV; CIRRHOSIS; HBV HCV COINFECTIONRetrospective StudiesHepatologybusiness.industryCarcinomaCancerHepatocellularmedicine.diseasedigestive system diseasesblood/etiology/pathologybusiness
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In HCV-related liver cirrhosis, local pulse wave velocity increases and in decompensated patients correlates with poorer survival

2018

BackgroundCirrhotic cardiomyopathy (CCM) refers to cardiac dysfunction in patients with liver cirrhosis, in the absence of other known cardiac disease.MethodsControl group and patients diagnosed of liver cirrhosis without known cardiac disease or hepatocellular carcinoma were enrolled for this clinical observation study. Patients with diabetes mellitus, hypertension were excluded. Absolute global longitudinal strain, one-point carotid pulse wave velocity (one-point PWV) and various parameters were measured in resting status.ResultsThere were 29 participants in the control group and 80 patients in the liver cirrhosis group. 27.8% of cirrhotic patients presented with normal systolic but abnor…

Liver CirrhosisMaleRNA virusesCirrhosisEtiologySocial SciencesHepacivirus030204 cardiovascular system & hematologyMathematical and Statistical Techniques0302 clinical medicineMedicine and Health SciencesPsychologyCardiac OutputPulse wave velocityPathology and laboratory medicineMultidisciplinaryHepatitis C virusLiver DiseasesQStatisticsRHepatitis CMiddle AgedMedical microbiologyHepatitis CAddictsCirrhosisHepatocellular carcinomaVirusesPhysical SciencesCardiologyMedicineRegression AnalysisFemale030211 gastroenterology & hepatologyPathogensCardiomyopathiesResearch ArticleAdultHepatitis B virusmedicine.medical_specialtyDeath RatesScienceCardiologyDiastoleAddictionGastroenterology and HepatologyPulse Wave AnalysisResearch and Analysis MethodsMicrobiology03 medical and health sciencesPopulation MetricsInternal medicineDiabetes mellitusmedicineHumansAlcoholicsStatistical MethodsAgedHepatitisBiology and life sciencesFlavivirusesPopulation Biologybusiness.industryOrganismsViral pathogensmedicine.diseaseHepatitis virusesCirrhotic cardiomyopathyMicrobial pathogensbusinessMathematicsPLOS ONE
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Changing aetiological factors of hepatocellular carcinoma and their potential impact on the effectiveness of surveillance

2011

BACKGROUND: The aetiological factors of hepatocellular carcinoma may vary over time. AIMS: The study assessed the potential impact of the aetiological factors on the effectiveness of surveillance in real-world patients. METHODS: Multicentre, cross-sectional study enrolling consecutive hepatocellular carcinoma cases during a six month period. RESULTS: 1733 cases (1311 prevalent and 422 incident) were recruited (mean age 68.6 years; 46.1% cases over 70 years; 73.9% males; 95.3% with cirrhosis); 63.0% were hepatitis C virus positive and 23.7% were virus negative. Amongst incident HCCs, 34.5% were single ≤3cm and 54.4% met the Milan criteria; 61.6% were diagnosed during surveillance; virus nega…

Liver CirrhosisMalemedicine.medical_specialtyCarcinoma HepatocellularEpidemiologyHepatocellular carcinomaCross-sectional studyCancer stageCancer stage; Epidemiology; Hepatitis; Hepatocellular carcinoma; Surveillance; Age Distribution; Aged; Carcinoma Hepatocellular; Cross-Sectional Studies; Female; Hepatitis B Surface Antigens; Hepatitis C Antibodies; Humans; Incidence; Italy; Liver Cirrhosis; Liver Neoplasms; Logistic Models; Male; Middle Aged; Multivariate Analysis; Prevalence; Ultrasonography; Population Surveillance; Hepatology; GastroenterologyMilan criteriaHepatitisAge DistributionInternal medicineEpidemiologyPrevalenceCarcinomaHumansMedicineHCCAgedUltrasonographyHepatitisHepatitis B Surface AntigensSurveillanceHepatologybusiness.industryIncidenceIncidence (epidemiology)CarcinomaLiver NeoplasmsCancer stage Epidemiology Hepatitis Hepatocellular carcinoma SurveillanceGastroenterologyHepatocellularHepatitis C AntibodiesMiddle Agedmedicine.diseaseETIOLOGYSurgeryCross-Sectional StudiesLogistic ModelsItalyHepatitis C Virus PositivePopulation SurveillanceHepatocellular carcinomaMultivariate AnalysisSURBVEILLANCEFemalebusiness
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Spontaneous Bacterial Peritonitis: A Prospective Investigation in Predominantly Nonalcoholic Cirrhotic Patients

1983

Two hundred and twenty-four consecutive inpatients with cirrhosis, mostly of nonalcoholic etiology, and ascites were prospectively investigated on admission for spontaneous bacterial peritonitis (SBP) by culture, smear, and polymorphonuclear (PMN) counts of ascitic fluid. Positive cultures were found in 54 patients. A possible intraabdominal source of infection was apparent in five of them, all with clinically overt peritonitis (secondary peritonitis). No intraabdominal source of infection was identified in the remaining 49. These patients were classified into the following groups: (a) SBP, 27 patients (positive cultures plus PMN counts ± 250 per mm3). Nine of them had no clinical features …

Liver CirrhosisMalemedicine.medical_specialtyCirrhosismedicine.drug_classAntibioticsPeritonitisPeritonitisGastroenterologySpontaneous bacterial peritonitisInternal medicineAscitesHumansMedicineProspective StudiesProspective cohort studyAgedHepatologybusiness.industryAscitesBacterial InfectionsMiddle Agedmedicine.diseaseSurgeryEtiologyPositive cultureFemalemedicine.symptombusinessHepatology
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The association between education level and chronic liver disease of any etiology

2020

Abstract Background The potential link between educational level and chronic liver diseases (CLD) were explored using the mortality records of liver cirrhosis, which lack accuracy and are unable to identify the different etiological factors of liver cirrhosis. Information on the association of low educational level with the severity of CLD is lacking. Aim To evaluate the potential association linking education level to etiology and clinical stage of CLD cases. Methods Consecutive enrolment of 11,107 subjects with CLD aged≥18 years prospectively recruited in two national surveys in 2001 and 2014 at one of the participating Italian liver units throughout the country. Subjects were pooled in t…

Liver Cirrhosismedicine.medical_specialtyCirrhosisAlcohol DrinkingLiver CirrhosiDisease030204 cardiovascular system & hematologyEducational settingChronic liver diseaseLogistic regressionChronic disease03 medical and health sciences0302 clinical medicineNon-alcoholic Fatty Liver DiseaseInternal medicineHBVInternal MedicinemedicineHumans030212 general & internal medicineStage (cooking)Association (psychology)Non-alcoholic Fatty Liver Disease.business.industryLiver DiseasesLiver DiseaseFatty liverMiddle Agedmedicine.diseaseItalyHCVEtiologyLiver disorderAlcoholbusinessHumanLiver disordersEuropean Journal of Internal Medicine
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