Search results for "FLAG"

showing 10 items of 174 documents

Kif3a interacts with Dynactin subunit p150 Glued to organize centriole subdistal appendages.

2013

Formation of cilia, microtubule-based structures that function in propulsion and sensation, requires Kif3a, a subunit of Kinesin II essential for intraflagellar transport (IFT). We have found that, Kif3a is also required to organize centrioles. In the absence of Kif3a, the subdistal appendages of centrioles are disorganized and lack p150(Glued) and Ninein. Consequently, microtubule anchoring, centriole cohesion and basal foot formation are abrogated by loss of Kif3a. Kif3a localizes to the mother centriole and interacts with the Dynactin subunit p150(Glued) . Depletion of p150(Glued) phenocopies the effects of loss of Kif3a, indicating that Kif3a recruitment of p150(Glued) is critical for s…

CentrioleKnockoutKinesinsBiologycentriole cohesionKif3aMedical and Health SciencesArticleGeneral Biochemistry Genetics and Molecular BiologyMiceMicrotubuleIntraflagellar transportInformation and Computing SciencesAnimalsHumansKIF3AMicrotubule anchoringMolecular BiologyCentriolesMice KnockoutGeneral Immunology and MicrobiologyGeneral NeuroscienceCiliumTumor Suppressor ProteinsNuclear ProteinsKinesinDynactin ComplexBiological SciencesCell biologyCytoskeletal ProteinscentrosomeCentrosomeHela CellsDynactinGeneric health relevanceMicrotubule-Associated Proteinsp150(Glued)HeLa Cellssubdistal appendageDevelopmental Biology
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The retinitis pigmentosa protein RP2 links pericentriolar vesicle transport between the Golgi and the primary cilium.

2010

Photoreceptors are complex ciliated sensory neurons. The basal body and periciliary ridge of photoreceptors function in association with the Golgi complex to regulate the export of proteins from the inner segment to the outer segment sensory axoneme. Here, we show that the retinitis pigmentosa protein RP2, which is a GTPase activating protein (GAP) for Arl3, localizes to the ciliary apparatus, namely the basal body and the associated centriole at the base of the photoreceptor cilium. Targeting to the ciliary base was dependent on N-terminal myristoylation. RP2 also localized to the Golgi and periciliary ridge of photoreceptors, which suggested a role for RP2 in regulating vesicle traffic an…

CentriolePhotoreceptor Connecting CiliumGolgi ApparatusBiologysymbols.namesakeMiceIntraflagellar transportGTP-Binding ProteinsGeneticsBasal bodyAnimalsHumansKIF3APhotoreceptor CellsCiliaEye ProteinsTransport VesiclesMolecular BiologyGenetics (clinical)Cells CulturedCentriolesADP-Ribosylation FactorsCiliumCiliary BodyIntracellular Signaling Peptides and ProteinsMembrane ProteinsBiological TransportGeneral MedicineGolgi apparatusCell biologysymbolssense organsCiliary baseRetinitis PigmentosaHuman molecular genetics
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Imprimitive groups highly transitive on blocks

2004

We classify imprimitive groups acting highly transitively on blocks and satisfying conditions common in geometry. They can be realized as suitable subgroups of twisted wreath products.

CombinatoricsTransitive relationAlgebra and Number TheoryFlag-transitiveSocleMathematicsJournal of Group Theory
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The Symbolical Realm and Historical Framework of the Contrade

2017

The chapter describes the contemporary symbolism of the contrade and its historic development in order to allow the reader to follow the subsequent analysis of the content of the contrade’s websites, in which symbols play a key role. It suggests that the contrade of Siena make significant use of mediaeval and Renaissance signs and symbol s such as particular colours, flags, and instruments. Members of a contrada build a community based on a specific district of Siena, and their lives are heavily focused on what is deemed necessary to the win a horse race called palio .

Community basedSymbolRace (biology)Historymedia_common.quotation_subjectRealmFLAGS registerThe RenaissanceOrder (virtue)media_commonKey (music)Visual arts
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Functional consequences of prey acclimation to ocean acidification for the prey and its predator

2016

Ocean acidification is the suite of chemical changes to the carbonate system of seawater as a consequence of anthropogenic carbon dioxide (CO2) emissions. Despite a growing body of evidences demonstrating the negative effects of ocean acidification on marine species, the consequences at the ecosystem level are still unclear. One factor limiting our ability to upscale from species to ecosystem is the poor mechanistic understanding of the functional consequences of the observed effects on organisms. This is particularly true in the context of species interactions. The aim of this work was to investigate the functional consequence of the exposure of a prey (the mussel Brachidontes pharaonis) t…

Condition indexRegistration number of speciesSalinityTemperateBottles or small containers/Aquaria (<20 L)inorganicAlkalinityBrachidontes pharaonisIncubation durationExperimentTemperature waterCarbon inorganic dissolvedAssimilation efficiencyEriphia verrucosaBreaking loadCalculated using seacarb after Nisumaa et al 2010Aragonite saturation stateAlkalinity totalBottles or small containers Aquaria 20 LtotalpHTemperaturePartial pressure of carbon dioxide (water) at sea surface temperature (wet air) standard errordissolvedCarbonate ionLaboratory experimentPartial pressure of carbon dioxide (water) at sea surface temperature (wet air)standard errorEarth System ResearchUniform resource locator link to referenceanimal structuresCalcite saturation stateArthropodaLengthwaterGrowth MorphologyFigureBenthosUniform resource locator/link to referenceMediterranean SeaAnimaliaBehaviourBicarbonate ionTime in secondsTypeTemperature water standard errorCalculated using seacarb after Nisumaa et al. (2010)SpeciespH standard errorCalcite saturation state standard errorGrowth rateBottles or small containers/Aquaria (&lt;20 L)Calculated using CO2SYSfungiCarbonate system computation flagFugacity of carbon dioxide (water) at sea surface temperature (wet air)CarbonTreatmentAragonite saturation state standard errorPartial pressure of carbon dioxide water at sea surface temperature wet airCarbon dioxideMolluscaGrowth/MorphologyBenthic animalsFugacity of carbon dioxide water at sea surface temperature wet airCoast and continental shelfSpecies interaction
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The Origin of Isolated Populations of the Mountain Weevil, Liparus glabrirostris—The Flagship Species for Riparian Habitats

2020

AbstractLiparus glabrirostris is one of the largest European weevils, and it has been recently proposed as the flagship species for threatened riparian habitats in the mountains. For effective conservation of its populations (and associated habitats), it is crucial to understand its history, contemporary distribution, genetic diversity and predict changes in the range, including its highly isolated populations on the Baltic coast. Here, we examined numerous populations of L. glabrirostris across almost the entire species range using phylogeography and species niche modeling (SNM) approaches. Analyses of mtDNA and nucDNA markers revealed the existence of 2 major mitochondrial lineages genera…

Conservation geneticsGenetic MarkersConservation of Natural ResourcesRange (biology)Species distributionBiologyphylogeographyspecies distribution modelingDNA MitochondrialCurculionidaeGeneticsFlagship speciesAnimalsMolecular BiologyGenetics (clinical)EcosystemRiparian zoneCell Nucleusgeographygeography.geographical_feature_categoryEcologyEnvironmental niche modellingEuropeColeopteraPhylogeographyGenetics PopulationRefugiumconservation geneticsThreatened speciesWeevilsBiotechnologyJournal of Heredity
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Definition of &amp;quot;banner clouds&amp;quot; based on time lapse movies

2007

Abstract. Banner clouds appear on the leeward side of a mountain and resemble a banner or a flag. This article provides a comprehensive definition of "banner clouds". It is based primarily on an extensive collection of time lapse movies, but previous attempts at an explanation of this phenomenon are also taken into account. The following ingredients are considered essential: the cloud must be attached to the mountain but not appear on the windward side; the cloud must originate from condensation of water vapour contained in the air (rather than consist of blowing snow); the cloud must be persistent; and the cloud must not be of convective nature. The definition is illustrated and discussed …

ConvectionAtmospheric ScienceMeteorologybusiness.industryCondensationBannerCloud computingBlowing snowbusinessWater vaporGeologyFlag (geometry)Atmospheric Chemistry and Physics
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Evidence of Genomic Instability in Campylobacter jejuni Isolated from Poultry

1998

ABSTRACT Poultry isolates of Campylobacter jejuni derived from a survey of meat processing batches were genotyped by pulsed-field gel electrophoresis (PFGE) of chromosomal DNA to establish the clonal relationships between single-colony isolates. In the majority of batches studied, one or two genotype patterns predominated. However, in one batch (batch A), 21 single-colony isolates gave 14 different PFGE genotypes. The banding patterns obtained with Sma I were sufficiently different to distinguish between genotypes, although the patterns also produced many common bands. The question of whether these isolates represented different clones or had a common clonal ancestry was addressed by additi…

DNA BacterialGenotypeGenetics and Molecular BiologyBiologyApplied Microbiology and BiotechnologyCampylobacter jejuniPoultrySmaIMicrobiologyCampylobacter jejuniGenotypePulsed-field gel electrophoresisAnimalsTypingGenomic organizationGeneticsEcologyGenetic Variationbiology.organism_classificationElectrophoresis Gel Pulsed-Fieldbiology.proteinRestriction fragment length polymorphismChickensGenome BacterialFlagellinFood ScienceBiotechnologyApplied and Environmental Microbiology
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Hoeflea alexandrii sp. nov., isolated from the toxic dinoflagellate Alexandrium minutum AL1V

2006

A Gram-negative, aerobic, non-symbiotic bacterium (AM1V30(T)) was isolated from the toxic dinoflagellate Alexandrium minutum AL1V. On the basis of 16S rRNA gene sequence similarity, strain AM1V30(T) was most closely related (97.4 % similarity) to the type strain of Hoeflea marina, which belongs to the family Phyllobacteriaceae within the order Rhizobiales of the class Alphaproteobacteria. A polyphasic approach was used to clarify the taxonomic position of strain AM1V30(T). During the course of this study, a second species was described by others as belonging to the genus Hoeflea, namely Hoeflea phototrophica; it showed a somewhat higher level of 16S rRNA gene sequence similarity with respec…

DNA BacterialMolecular Sequence DataMarine BiologyMicrobiologyAlgaeSpecies SpecificityPhylogeneticsRNA Ribosomal 16SSequence Homology Nucleic AcidCentro Oceanográfico de VigoBotanyProteobacteriaAnimalsMedio MarinoEcology Evolution Behavior and SystematicsPhylogenyGeneticsBase CompositionbiologyFatty AcidsDinoflagellateGeneral MedicineRibosomal RNAbiology.organism_classification16S ribosomal RNARNA BacterialSpainDinoflagellidaTaxonomy (biology)HoefleaBacteria
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LrhA as a new transcriptional key regulator of flagella, motility and chemotaxis genes in Escherichia coli

2002

The function of the LysR-type regulator LrhA of Escherichia coli was defined by comparing whole-genome mRNA profiles from wild-type E. coli and an isogenic lrhA mutant on a DNA microarray. In the lrhA mutant, a large number (48) of genes involved in flagellation, motility and chemotaxis showed relative mRNA abundances increased by factors between 3 and 80. When a representative set of five flagellar, motility and chemotaxis genes was tested in lacZ reporter gene fusions, similar factors for derepression were found in the lrhA mutant. In gel retardation experiments, the LrhA protein bound specifically to flhD and lrhA promoter DNA (apparent K-D approximate to 20 nM), whereas the promoters of…

DNA BacterialbindingTranscription GeneticRecombinant Fusion ProteinsMolecular Sequence DataMutantacetyl phosphatelac operonBiologymedicine.disease_causeMicrobiologyh-ns proteink-12lysr homologBacterial ProteinsGenes ReporterTranscription (biology)expressionEscherichia colimedicinernaRNA MessengerPromoter Regions GeneticMolecular BiologyGeneEscherichia coliDerepressionOligonucleotide Array Sequence AnalysisBase SequenceChemotaxisEscherichia coli ProteinsGene Expression ProfilingPromoterChemotaxisGene Expression Regulation BacterialMolecular biologyco2 fixationmaster operonDNA-Binding ProteinsRNA BacterialLac OperonFlagellaTrans-ActivatorssignalTranscription Factors
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