Search results for "FP"

showing 10 items of 297 documents

An Efficient Hardware Architecture for the HEVC Intra Prediction

2014

International audience; A novel intra prediction hardware architecture forthe High Efficiency Video Coding (HEVC) is presented in thispaper in order to reduce the computation complexity within thisstandard and to accelerate the concerned calculations, and thusto process more and more of video frames at high resolutions. Wepropose a new pipelined structure that we called ProcessingElement (PE) to calculate the angular prediction modes, and werepeat it in three paths that our design composed of. And wepresent, in this paper, a dynamic structure to carry out thePlanar mode. This architecture supports all intra predictionmodes for 8x8 and 4x4 prediction unit sizes. The synthesis resultsshow tha…

Intra prediction[ INFO.INFO-TS ] Computer Science [cs]/Signal and Image Processing[INFO.INFO-TS]Computer Science [cs]/Signal and Image Processing[INFO.INFO-TS] Computer Science [cs]/Signal and Image ProcessingHEVC standardFPGA
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The Friedreich's Ataxia protein frataxin modulates DNA base excision repair in prokaryotes and mammals

2010

DNA-repair mechanisms enable cells to maintain their genetic information by protecting it from mutations that may cause malignant growth. Recent evidence suggests that specific DNA-repair enzymes contain ISCs (iron–sulfur clusters). The nuclearencoded protein frataxin is essential for the mitochondrial biosynthesis of ISCs. Frataxin deficiency causes a neurodegenerative disorder named Friedreich's ataxia in humans. Various types of cancer occurring at young age are associated with this disease, and hence with frataxin deficiency. Mice carrying a hepatocyte-specific disruption of the frataxin gene develop multiple liver tumours for unresolved reasons. In the present study, we show that frata…

Iron-Sulfur ProteinsDNA Repairmedicine.disease_causeBiochemistryDNA Glycosylases8-oxoG 78-dihydro-8-oxoguanineMice0302 clinical medicineIron-Binding Proteinsoxidative stressBER base excision repairCells CulturedMammalsMice Knockout0303 health sciencesfrataxinDMEM Dulbecco's modified Eagle's mediumbiologyLiver NeoplasmsSalmonella entericairon–sulfur clusterLife SciencesIron-binding proteinsTransfection3. Good healthLB Luria–BertaniOGG1 8-oxoguanine DNA glycosylase 1ISC iron–sulfur clusterFpg formamido-pyrimidine DNA glycosylaseHPRT hypoxanthine phosphoribosyltransferaseResearch ArticleDNA damageDNA repairSSB DNA single-strand breakTransfectionCell Line03 medical and health sciencesFRDA Friedreich's ataxiaROS reactive oxygen speciesmedicineAnimalsHumansMUTYH human mutY homologue (Escherichia coli)Molecular BiologyGene030304 developmental biologyFriedreich's ataxiaCell BiologyFibroblastsMolecular biologytumorigenesisProkaryotic CellsFriedreich AtaxiaDNA base excision repairDNA glycosylaseMutationHepatocytesFrataxinbiology.proteinInstitut für ErnährungswissenschaftCarcinogenesisMAPK mitogen-activated protein kinase030217 neurology & neurosurgeryDNA Damage
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The paradoxical management of service skills

2015

This paper focuses on service skills which are mobilized by front office agents when they are involved with customers. These skills are most of the time tacit. We consider that the way in which firms recognize these skills and contribute to their development is an important management issue. It is all the more important that a lot of jobs combine poor levels of qualification and highly situated skills.

JEL: M - Business Administration and Business Economics • Marketing • Accounting • Personnel Economics/M.M5 - Personnel Economics/M.M5.M53 - TrainingFPC en entreprisesavoir professionnelrelationship skillsIRG_AXE2CVT in companiesJEL: J - Labor and Demographic Economics/J.J2 - Demand and Supply of Labor/J.J2.J24 - Human Capital • Skills • Occupational Choice • Labor ProductivityJEL : J - Labor and Demographic Economics/J.J2 - Demand and Supply of Labor/J.J2.J24 - Human Capital • Skills • Occupational Choice • Labor ProductivityJEL: M - Business Administration and Business Economics • Marketing • Accounting • Personnel Economics/M.M5 - Personnel Economics/M.M5.M54 - Labor Management[SHS.GESTION]Humanities and Social Sciences/Business administrationprofessional knowledgeJEL : M - Business Administration and Business Economics • Marketing • Accounting • Personnel Economics/M.M5 - Personnel Economics/M.M5.M53 - TrainingJEL : M - Business Administration and Business Economics • Marketing • Accounting • Personnel Economics/M.M5 - Personnel Economics/M.M5.M54 - Labor Management[ SHS.GESTION ] Humanities and Social Sciences/Business administration[SHS.GESTION] Humanities and Social Sciences/Business administrationskillcompétence relationnellecompétence
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Validation of the German version of the Kujala score in patients with patellofemoral instability : a prospective multi-centre study

2017

Introduction: The Kujala score is the most frequently used questionnaire for patellofemoral disorders like pain, instability or osteoarthritis. Unfortunately, we are not aware of a validated German version of the Kujala score. The aim of our study was the translation and linguistic validation of the Kujala score in German-speaking patients with patella instability and the assessment of its measurement characteristics. Materials and methods: The German Kujala score was developed in several steps of translation. In addition to healthy controls, the Kujala German was assessed in consecutive patients undergoing reconstruction of the medial patellofemoral ligament for recurrent patellar dislocat…

Joint Instabilitymedicine.medical_specialtyKnee JointpolvetkyselytutkimussijoiltaanmenoMedial patellofemoral ligamentLinguistic validationSeverity of Illness IndexPatellofemoral pain syndrome (PFPS)GermanPatellofemoral Joint03 medical and health sciences0302 clinical medicineQuality of lifeCronbach's alphaSurveys and QuestionnairesValidationmedicineHumansOrthopedics and Sports Medicine030222 orthopedicsQuestionnairebusiness.industryKujala scorequestionnairepatellofemoral instabilityDiscriminant validityoireyhtymätkipu030229 sport sciencesGeneral MedicinePatellofemoral instabilityArthralgiaKujala patellofemoral scorelanguage.human_languageArthroscopy and Sports Medicinemedicine.anatomical_structureConvergent validityvalidointiLigaments ArticularOrthopedic surgerylanguagePhysical therapySurgerybusiness
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Mitochondrial and redox dysfunction in post-menopause as risk factor of neurodegenerative disease: a pilot study testing the role of a validated Japa…

2020

During the menopause women may experience increased oxidative stress and decreased antioxidant capacity and, together with the decline of neurosteroids, this represents a risk factor for Alzheimer's disease. The aim of the present study was to test a functional food (FPP-ORI, Osato Research Institute, Gifu, Japan) on redox and mitochondrial efficiency in post-menopausal women. The study population consisting of 69 untreated post-menopausal women were given supplements as follows: Group A was given a multivitamin (MV) 1c 2 times a day, and group B was given FPP 4.5 g 2 times a day. Group C consisted of 23 fertile premenopausal women as the control group. The tests carried out on entry, and a…

MDAmenopausePilot ProjectsAntioxidantsElectron Transport Complex IVFPP-ORIJapanFunctional FoodRisk FactorsMalondialdehydeBDNF; COX activity; FPP-ORI; GPx; MDA; SOD1; menopause; mitochondria; redox dysfunctionHumansGPxBrain-Derived Neurotrophic FactorNeurodegenerative DiseasesSOD1PostmenopauseCOX activitymitochondriaOxidative StressBDNFLeukocytes Mononuclearredox dysfunctioncFemaleCOX activity.Oxidation-Reductionredox dysfunction
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Les cités de la gastronomie

2016

MFPCAgastronomieCitéPCIidentité[SHS.INFO] Humanities and Social Sciences/Library and information sciences
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Technics Amélioration for geo-localization in wsn via smart computing and real time application

2022

New technologies exploiting digital information acquisition by radio frequency techniques are now commonly used in various practical fields. They are most often used to measure a variety of physical variables such as temperature, humidity, speed, etc. and are gathered under the name of Wireless Sensor Networks “WSN”. For this variant of applications, the accurate location of connected sensor nodes remains an important issue for researchers and industrial applications. Indeed, existing localization algorithms can be classified into two categories known as « range-based » and « range-free ». Range-based localization systems are characterized by major drawbacks. The first one is the cost of th…

Machine LearningHlsLocalizationRcsfImplémentation MatérielleMachine d'ApprentissageFPGA ImplementationWsnLocalisation[SPI.TRON] Engineering Sciences [physics]/Electronics
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Technology spillover and TFP growth: A spatial Durbin model

2016

Beginning with a model in which technological progress is reflected by product variety, we provide a structural approach to estimate technology spillovers allowing for spatial interdependencies. To this end, we first present a theoretical model of TFP growth by decomposing TFP into quality and variety components. We address the quality component by introducing a country׳s distance to the technological frontier. Quality is assumed to be a negative function of the technological gap of country i with respect to its own technological frontier. This technological threshold is defined as the geometric means of knowledge levels in all countries. We deal with the variety component by using R&D expe…

MacroeconomicsTFP GrowthTechnological changemedia_common.quotation_subject05 social sciences[SHS.ECO]Humanities and Social Sciences/Economics and FinanceSpatial Durbin ModelGeneral Business Management and AccountingHuman capitalInterdependenceSpillover effectTechnology Spillover0502 economics and businessEconomicsEconometrics[ SHS.ECO ] Humanities and Social Sciences/Economies and finances050207 economics[SHS.ECO] Humanities and Social Sciences/Economics and FinanceGeneral Economics Econometrics and FinanceTotal factor productivityProductivitySpatial analysisStock (geology)050205 econometrics media_commonInternational Economics
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Reduced firing rates of pyramidal cells in the frontal cortex of APP/PS1 can be restored by acute treatment with levetiracetam

2020

Contains fulltext : 229488.pdf (Publisher’s version ) (Open Access) Contains fulltext : 229488pre.pdf (Author’s version preprint ) (Open Access) In recent years, aberrant neural oscillations in various cortical areas have emerged as a common physiological hallmark across mouse models of amyloid pathology and patients with Alzheimer's disease. However, much less is known about the underlying effect of amyloid pathology on single cell activity. Here, we used high-density silicon probe recordings from frontal cortex area of 9-month-old APP/PS1 mice to show that local field potential power in the theta and beta band is increased in transgenic animals, whereas single-cell firing rates, specifica…

Male0301 basic medicineAgingAlzheimer`s disease Donders Center for Medical Neuroscience [Radboudumc 1]LevetiracetamAction PotentialsamyloidoosiLocal field potentialAlzheimerin tautiAmyloid beta-Protein Precursor0302 clinical medicineBeta RhythmChemistryPyramidal CellsGeneral Neuroscienceamyloidfood and beveragesAmyloidosisPhenotypePathophysiologyFrontal Lobesingle cellmedicine.anatomical_structureLevetiracetamPyramidal cellAlzheimer’s diseasemedicine.drugNeuroinformaticspatofysiologiaAmyloidmouse modelTransgeneMice Transgenic03 medical and health sciencesAlzheimer Diseasemental disordersPresenilin-1medicineAnimalslocal field potential (LFP)hermosolutDisease Models Animal030104 developmental biologynervous systemfiring rateNeurology (clinical)Geriatrics and GerontologyNeuroscience030217 neurology & neurosurgeryDevelopmental BiologyNeurobiology of Aging
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The SGLT2 inhibitor empagliflozin improves the primary diabetic complications in ZDF rats

2017

Hyperglycemia associated with inflammation and oxidative stress is a major cause of vascular dysfunction and cardiovascular disease in diabetes. Recent data reports that a selective sodium-glucose co-transporter 2 inhibitor (SGLT2i), empagliflozin (Jardiance®), ameliorates glucotoxicity via excretion of excess glucose in urine (glucosuria) and significantly improves cardiovascular mortality in type 2 diabetes mellitus (T2DM). The overarching hypothesis is that hyperglycemia and glucotoxicity are upstream of all other complications seen in diabetes. The aim of this study was to investigate effects of empagliflozin on glucotoxicity, β-cell function, inflammation, oxidative stress and endothel…

Male0301 basic medicineendocrine system diseasesDiabetic CardiomyopathiesFPS-ZM1 RAGE inhibitorClinical BiochemistryAorta ThoracicRAGE receptor for AGEICAM-1 intercellular adhesion molecule-1ECL enhanced chemiluminescence030204 cardiovascular system & hematologyDPP-4 dipeptidyl peptidase-4medicine.disease_causeTNF-α tumor necrosis factor-αBiochemistryeNOS endothelial •NO synthase (type 3)0302 clinical medicineGlucosidesecSOD extracellular superoxide dismutaseInsulin-Secreting CellsCCL-2 see MCP-1HyperlipidemiaHyperinsulinemiaGTN glyceryl trinitrate (nitroglycerin)IFN-γ interferon-γDHE dihydroethidineEndothelial dysfunctionEndothelial dysfunctionIL-6 interleukin-6lcsh:QH301-705.5HO-1 heme oxygenase-1lcsh:R5-920ICAM-1NG normoglycemiaDiabetesNox catalytic subunit of NADPH oxidaseSGLT2 inhibitorβ-cell contentL-012 8-amino-5-chloro-7-phenylpyrido[34-d]pyridazine-14-(2H3H)dione sodium saltChIP chromatin immunoprecipitationC-Reactive ProteinCRP C-reactive proteinAGE advanced glycation end productsHbA1c glycohemoglobinlcsh:Medicine (General)Research PaperZucker diabetic fatty ratsmedicine.medical_specialtyDMSO dimethylsulfoxideMCP-1 monocyte-chemoattractant-protein-1qRT-PCR quantitative reverse transcription polymerase chain reactionZDF Zucker diabetic fatty (rat)Low-grade inflammation03 medical and health sciencesROS reactive oxygen speciesSodium-Glucose Transporter 2Physiology (medical)Internal medicineDiabetes mellitusPKC protein kinase CEmpagliflozinmedicineAnimalsHypoglycemic AgentsBenzhydryl CompoundsCOX2 cyclooxygenase-2SGLT2i SGLT2 inhibitorSodium-Glucose Transporter 2 InhibitorsGlycated HemoglobinACh acetylcholinebusiness.industryOrganic Chemistrynutritional and metabolic diseasesType 2 Diabetes Mellitusmedicine.diseaseH2K9me2 histone3 lysine9 dimethylationRatsRats ZuckerDHFR dihydrofolate reductaseSGLT2 sodium-glucose co-transporter-2Oxidative StresssGC soluable guanylyl cyclaseGlucose030104 developmental biologyEndocrinologylcsh:Biology (General)ALDH-2 mitochondrial aldehyde dehydrogenaseEndothelium VascularAGE/RAGE signalingHG hyperglycemiabusinessOxidative stressRedox Biology
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