Search results for "Figur"

Stereochemistry of terpene derivatives. Part 3: Hydrolytic kinetic resolution as a convenient approach to chiral aminohydroxyiminocaranes with local …

2002

Abstract We have developed a stereoselective hydrolytic kinetic resolution process for diastereoisomeric mixtures of epoxyiminocarene intermediates in the presence of ( R , R )-(−)-(salen)Co(III)OAc catalyst, this was applied as the first step in the synthesis of novel chiral aminohydroxyiminocarane derivatives with local anaesthetic activity. The absolute configuration of the product was confirmed by X-ray crystallography.

Modeling of low-noise microwave HEMTs for CAD-oriented applications

1993

The simultaneous determination of noise, gain and scattering parameters through a computer-driven noise figure measuring system allowed the rapid and accurate characterization of several samples of low noise HEMTs of the same family. From the measured parameters an equivalent circuit model representing the behavior of the typical device is extracted by means of a decomposition approach. Comparison between the model performance and the set of measured parameters of all devices are reported for the FHR 02FH (by Fujitsu). The modeling procedure is mainly oriented to the CAD of (M)MIC low noise wideband amplifiers. © 1993 John Wiley & Sons, Inc.

Evolución histórica de la autonomía de la voluntad en el Derecho matrimonial

2021

The autonomy of the will or power of self-regulation of relationships derived from marriage is a subject that is on the rise and that we can qualify as novel. More and more couples are opting to proceed making use of this power to self-regulate both personal and property effects derived from their union or its future breakdown. In the Spanish legal system there is no precise and complete regulation of the subject, without all these figures being equally legislated, although all are admitted without any doubt by jurisprudence. In recent years there has been an evolution of Family law, traditionally very reluctant to give space to self-regulation. Our Constitution marks a turning point by cha…

Swarming : An Investigation Practice Supporting a Bottom-up Ecological Transition

2022

Dans cet article, nous rendons compte des pratiques d’essaimage d’initiatives locales de transition portées par des collectifs citoyens et associatifs en région Bourgogne Franche-Comté. L’essaimage, défini comme une façon d’enquêter pour agir, caractérise un « activisme environnemental du faire » qui se structure de manière réticulaire et translocale. Ces multiples initiatives qui font des gestes du quotidien un levier de transformation écologique s’activent avec ou sans les institutions territoriales. Celles-ci, indépendamment de l’écho qu’elles renvoient à ces expérimentations, sont interpellées dans leur manière de concevoir l’action publique sous contrainte écologique forte.

Matières de table. Fantaisies gourmandes de Jacques Fontanille.

2021

Following the figurative trajectory of gustatory sensitivity in the work of Jacques Fontanille, three key moments stand out: (1) the entry through the sensory and the flavors, marked by the autonomy of the figurative dimension in the sensitive deployment of the flavor; (2) the putting to the test of the semiotic exploration in different fields of expression: at the table, through "the setting in plate", around the wine; (3) the figurative consistency of the food form as manifestation of a form of life, with its modalities and its modulations

Experimental and numerical analysis on post welding formability of FSWed AZ31 magnesium alloy thin joints obtained using a "Pinless" tool configurati…

2012

The post welding formability of friction stir welded AZ31 magnesium alloy thin sheets (1.5 mm thick), obtained using a “pinless” tool configuration, was widely investigated by means of the hemispherical punch method at 350°C, with a constant crosshead speed of 0.1 mm/s. The results were compared with those obtained on the base material. It has shown that formability of the joints is lower than the one of the base material. The experimental work was supported by a numerical investigation based on FEM in order to highlight the material flow occurring during the welding process. Additionally, hemispherical punch tests were simulated starting from the calculated conditions, in terms of accumula…

Experimental and numerical analysis on FSWed magnesium alloy thin sheets obtained using “pin” and “pinless” tool

2012

Acid rearrangment of epoxy-germacranolides and absolute configuration of 1beta, 10alpha-epoxy-salonitenolide

2010

The acid-catalyzed cyclization of mono epoxides of cnicin acetonide (3) was investigated. Several 6,12-eudesmanolides were obtained, and their stereochemistry established by extensive spectroscopic analyses. Chemical correlations also led to the assignment of the absolute configuration of 1beta,10alpha-epoxy-salonitenolide (13), a previously isolated natural product. The cytotoxic activities of some compounds were determined against A549 and MCF-7 tumor cell lines. The esterified germacranolides 2-6 were selectively cytotoxic against the MCF-7 breast cancer cell line.

A New Cacospongionolide Inhibitor of Human Secretory Phospholipase A2 from the Tyrrhenian Sponge Fasciospongia cavernosa and Absolute Configuration o…

1998

A new inhibitor of human secretory phospholipase A2 (PLA2), cacospongionolide E (4a), has been isolated from the Tyrrhenian sponge Fasciospongia cavernosa. The structure was proposed on the basis of spectroscopic data and by chemical transformations. The absolute configuration of cacospongionolides 2a-4a was established using the modified Mosher's method. Cacospongionolide E was the most potent inhibitor toward human synovial PLA2, showing higher potency than the reference compound manoalide and exerting no signs of toxicity on human neutrophils. It showed high activity in the Artemia salina bioassay and moderate toxicity in the fish (Gambusia affinis) lethality assay.

Sesquiterpenoids from the Endophytic Fungus Rhinocladiella similis

2019

Ten new sesquiterpenoid derivatives, rhinomilisins A-J (1-10), along with six known analogues (11-16), were isolated from the mangrove-derived endophytic fungus Rhinocladiella similis. The structures of the new compounds were elucidated by their NMR and MS data, while the absolute configuration of 3 and 6 was determined by X-ray crystallographic analysis and Mosher's method, respectively. All isolated compounds (1-16) were evaluated for their cytotoxicity against the mouse lymphoma cell line L5178Y, and compounds 1, 7, and 15 showed moderate activity with IC50 values of 5.0, 8.7, and 24.4 μM, respectively.