Search results for "GAIN"

showing 10 items of 625 documents

Factors Associated With Weight Gain in People Treated With Dolutegravir.

2020

AbstractBackgroundAn unexpected excess in weight gain has recently been reported in the course of dolutegravir (DTG) treatment. The aim of the present study was to investigate whether weight gain differs among different DTG-containing regimens.MethodsAdult naïve and experienced people with HIV (PWH) initiating DTG-based antiretroviral therapy (ART) between July 2014 and December 2019 in the Surveillance Cohort Long-Term Toxicity Antiretrovirals (SCOLTA) prospective cohort were included. We used an adjusted general linear model to compare weight change among backbone groups and a Cox proportional hazard regression model to calculate hazard ratios (HRs) and 95% confidence intervals (CIs) for …

0301 basic medicinemedicine.medical_specialtyWeight gain.HIV metabolic complications030106 microbiologyHIV metabolic complicationTDFEmtricitabineTenofovir alafenamidedolutegravir HIV metabolic complications TAF TDF weight gain.03 medical and health scienceschemistry.chemical_compound0302 clinical medicineAbacavirInternal medicinemedicineMajor Article030212 general & internal medicinebusiness.industryWeight changeLamivudineweight gaindolutegravirInfectious DiseasesAcademicSubjects/MED00290OncologychemistryTAFRilpivirineDolutegravirmedicine.symptombusinessWeight gainmedicine.drugOpen forum infectious diseases
researchProduct

Effects of Infant Formula With Human Milk Oligosaccharides on Growth and Morbidity: A Randomized Multicenter Trial

2017

Objectives:The aim of the study was to evaluate the effects of infant formula supplemented with 2 human milk oligosaccharides (HMOs) on infant growth, tolerance, and morbidity. Methods:Healthy infants, 0 to 14 days old, were randomized to an intact-protein, cow's milk-based infant formula (control, n=87) or the same formula with 1.0g/L 2fucosyllactose (2FL) and 0.5g/L lacto-N-neotetraose (LNnT) (test, n=88) from enrollment to 6 months; all infants received standard follow-up formula without HMOs from 6 to 12 months. Primary endpoint was weight gain through 4 months. Secondary endpoints included additional anthropometric measures, gastrointestinal tolerance, behavioral patterns, and morbidit…

0301 basic medicinesafetyMalePediatricsmedicine.medical_specialtyMEDLINEOligosaccharidesWeight Gainlaw.inventionbronchitis03 medical and health scienceschemistry.chemical_compound2'-FucosyllactoseRandomized controlled trialDouble-Blind Method2fucosyllactose; bronchitis; lacto-N-neotetraose; safety; tolerancelawMulticenter trialmedicineAnimalsHumansLacto-N-neotetraoseRespiratory Tract Infectionslacto-N-neotetraose2′fucosyllactose030109 nutrition & dieteticstoleranceMilk Humanbusiness.industryGastroenterologyOriginal Articles: NutritionInfant Newbornfood and beveragesInfantProtective Factorsmedicine.diseaseInfant Formula030104 developmental biologyMilkchemistryInfant formulaPediatrics Perinatology and Child Health2'fucosyllactose bronchitis lacto-N-neotetraose safety toleranceBronchitisFemalemedicine.symptombusinessWeight gainFollow-Up Studies
researchProduct

The Role of p53 Signaling in Colorectal Cancer.

2021

Simple Summary The transcription factor p53 is a crucial tumor suppressor that regulates diverse cellular responses to protect against cancer development. Deactivating p53 signaling either by altering p53 regulators or by p53 mutations occurs frequently in human colorectal carcinoma (CRC). Forty-three percent of CRCs harbor p53 mutations that reduce wild-type p53 tumor suppressor activity and often provide neo-morphic functions, which contribute to tumorigenesis. In this review, we summarize wild-type p53 signaling, how it can be deregulated in CRC, and the functional and phenotypical effects of p53 mutations. We also discuss current therapeutic strategies of targeting p53. Abstract The tra…

0301 basic medicinewild type p53Cancer ResearchDNA repairCellular differentiationcolorectal cancerReview03 medical and health sciences0302 clinical medicinemedicineTranscription factorRC254-282gain-of-functionbiologyCell growthmutant p53CancerNeoplasms. Tumors. Oncology. Including cancer and carcinogensmedicine.diseaseUbiquitin ligasep53 signaling030104 developmental biologyOncology030220 oncology & carcinogenesisCancer cellbiology.proteinCancer researchMdm2cancer therapyp53 pathwayCancers
researchProduct

Representation of Intimate Partner Violence Against Women in Swedish News Media: A Discourse Analysis.

2020

Despite being rated as some of the world’s most gender equal countries, Sweden and neighboring Nordic nations show high rates of intimate partner violence against women (IPVAW). As the news media contribute to the shaping of public attitudes, this article pursues a two-step discourse analysis of how IPVAW was represented in seven Swedish newspapers during 2018. Although an individualistic discourse on IPVAW was found to be most prevalent, articles where perpetrators were presented as non-Swedish more frequently contained a structural framing of IPVAW. This confirms previously noted tendencies toward individualization and othering of IPVAW in Sweden.

050402 sociologySociology and Political ScienceDiscourse analysisIntimate Partner ViolenceNewspaperRepresentation (politics)newspapersGender StudiesIndividualismintimate partner violence against women (IPVAW)0504 sociology050602 political science & public administrationHumansSociologyNews mediaResearch ArticlesHigh rateSweden05 social sciencesGender IdentityGender studiesNordic Paradox0506 political scienceFraming (social sciences)Sexual PartnersDomestic violenceFemalediscourseLawViolence against women
researchProduct

Varieties of State Aid and Technological Development: Government Support to the Pulp and Paper Industry, the 1970s to the 1990s

2018

Countries promote the development of pulp and paper industry through industrial, technology and innovation policy measures. Direct interventions and regional and environmental policies, together with more general governmental measures on trade negotiations, taxation, labour policies, and infrastructure development (e.g. roads, energy) have also had an impact on shaping the geographical location of and investments in the pulp and paper industry. This chapter presents an historical overview of government support on pulp and paper industry in the Organisation for Economic Co-operation and Development (OECD) countries from roughly the 1970s to the 1990s. As the earlier literature suggests, in c…

060106 history of social sciencesmedia_common.quotation_subjectIndustrial policyOECD-maatelinkeinopolitiikkaState (polity)Line of business0502 economics and businesssääntely0601 history and archaeology050207 economicsLocationmedia_commonGovernment05 social sciencesindustrial policy regulation1. No poverty222 Other engineering and technologies06 humanities and the artsmassa- ja paperiteollisuusPulp and paper industryNegotiationBargaining powerOECD8. Economic growthBusiness
researchProduct

Chapter 12 Role of Iron in Plant–Microbe Interactions

2009

Iron is an essential micronutrient for plants and associated microorganisms. Iron nutrition of these organisms relies on the soil supply. However, bioavailability of iron in cultivated soils is low. Plants and microorganisms have thus evolved active strategies of iron uptake based on acidification, chelation, and/or reduction processes. Iron acquisition by these organisms leads to complex interactions ranging from mutualism to competition. In the rhizosphere, plants support abundant and active microbial communities through the release of rhizodeposits. Iron uptake by these microorganisms and by the host plant decrease even more the concentration of iron in solution. Therefore, there is an i…

2. Zero hungerMutualism (biology)0303 health sciencesRhizosphereSiderophore030306 microbiologyMicroorganismfungifood and beveragesVirulencePlant microbeBiologyMicronutrient03 medical and health sciencesBotanyPlant defense against herbivory030304 developmental biology
researchProduct

Television in the bedroom and increased body weight: potential explanations for their relationship among European schoolchildren

2012

Summary Aims: A television in the bedroom is associated with measures of adiposity. We aimed to test if this association is mediated by any of (i) time spent watching television, (ii) sleep duration, (iii) physical activity level or (iv) consumption of soft drinks. Method: Data were from 7234 boys and girls aged 10–12 years in European countries involved in the EuropeaN Energy balance Research to prevent excessive weight Gain among Youth project (Belgium, Greece, Hungary, the Netherlands, Norway, Slovenia and Spain). Waist circumference, height and weight were measured. The presence of a bedroom television, television viewing time, sleep duration, physical activity time and soft drink consu…

2. Zero hungerPediatricsmedicine.medical_specialtyNutrition and DieteticsWaistbusiness.industryHealth PolicyPublic Health Environmental and Occupational HealthOverweightmedicine.diseaseObesityPhysical activity level03 medical and health sciencesScreen time0302 clinical medicine030225 pediatricsPediatrics Perinatology and Child Healthmedicine030212 general & internal medicinemedicine.symptombusinessBody mass indexWeight gainDemographyBedroomPediatric Obesity
researchProduct

El fundamento liberal del derecho a la intimidad

2021

T: The right to privacy is configured as a ?retaining wall? against State interference into the private sphere of people?s life. Throughout this work we will try to expose the philosophical-liberal foundations that have led us to what is now conceived as the ?right to privacy?.

:CIENCIAS JURÍDICAS [UNESCO]2070-8157 22082 Revista Boliviana de Derecho 584568 2021 32 8055215 El fundamento liberal del derecho a la intimidad Heras VivesGallego MoralesLuis de lasRight to privacyUNESCO::CIENCIAS JURÍDICASDaniel José T: The right to privacy is configured as a ?retaining wall? against State interference into the private sphere of people?s life. Throughout this work we will try to expose the philosophical-liberal foundations that have led us to what is now conceived as the ?right to privacy?. Derecho a la intimidadprivate sphere 70 95The right to privacy is configured as a ?retaining wall? against State interference into the private sphere of people?s life. Throughout this work we will try to expose the philosophical-liberal foundations that have led us to what is now conceived as the ?right to privacy?. Derecho a la intimidad [Daniel José T]liberalismoliberalismesfera privada
researchProduct

La negociación colectiva de empresa por representantes de base unitaria: el principio de correspondencia como límite jurisprudencial. Comentario a la…

2016

La Sentencia que ocupará las siguientes páginas aborda la legalidad de un convenio de empresa suscrito por un delegado de personal pero cuyo ámbito funcional pretende extenderse a la totalidad de la empresa. Impugnado el convenio por una Federación Sindical, la cual pretende que las condiciones de los trabajadores se sigan rigiendo por el convenio sectorial aplicable, la AN estima la pretensión de la parte actora, aplicando el principio de correspondencia. The Court ruling that we are analyzing decides the legality of an enterprise agreement signed by an elected representative, but whose functional scope intended to extend to the entire company. Challenged the agreement by Federation ofTrad…

:CIENCIAS JURÍDICAS [UNESCO]Delegado de personalDerechoElective representativeConvenio colectivoCollective bargainingIllegalityCiencias jurídicasUNESCO::CIENCIAS JURÍDICASNulidadPrincipio de correspondenciaIlegalidadCiencias jurídicas. GeneralidadesNullityCorrespondence principleEmpresa
researchProduct

Public policy in families and successions regulations : the case of ?talaq?

2021

According to EU Regulations on transnational families and successions, a foreign rule remains without effect if it is deemed contrary to the so-called public policy (ordre public) of the forum?s legal system. As a consequence, judges have to evaluate whether the application of foreign law is incompatible with fundamental principles of the domestic law, especially whether it would constitute a violation against human rights. An outstanding controversial issue is today represented by Islamic repudiation (talaq): two contrasting Italian judicial decisions of August 2020 may illustrate how difficult it could be to determine what public policy is.

:CIENCIAS JURÍDICAS [UNESCO]Marco According to EU Regulations on transnational families and successionsjudges have to evaluate whether the application of foreign law is incompatible with fundamental principles of the domestic law2386-4567 22661 Actualidad jurídica iberoamericana 587897 2021 15 8113559 Public policy in families and successions regulations the case of ?talaq? Rizzutimigrationhuman rightsa foreign rule remains without effect if it is deemed contrary to the so-called public policy (ordre public) of the forum?s legal system. As a consequenceespecially whether it would constitute a violation against human rights. An outstanding controversial issue is today represented by Islamic repudiation (talaq): two contrasting Italian judicial decisions of August 2020 may illustrate how difficult it could be to determine what public policy is. Public policymigracióntalaq. 221 241Orden públicoUNESCO::CIENCIAS JURÍDICAStwo contrasting Italian judicial decisions of August 2020 may illustrate how difficult it could be to determine what public policy is. Public policy [especially whether it would constitute a violation against human rights. An outstanding controversial issue is today represented by Islamic repudiation (talaq)]talaq.derechos humanos
researchProduct