Search results for "HUMAN HEALTH"
showing 10 items of 1622 documents
Table ronde
2017
Association of commonly used systemic medications with glaucoma prevalence and intraocular pressure across Europe: the E3 Consortium
2022
Purpose : To investigate the association of common systemic medication use with intraocular pressure and glaucoma prevalence in the European population.Methods : We examined associations of systemic medication use with intraocular pressure and glaucoma prevalence in a meta-analysis of multiple cohort studies of the European Eye Epidemiology (E3) consortium. IOP measurement method and glaucoma ascertainment were according to individual study protocols. Multivariable regression (linear for IOP and logistic for glaucoma prevalence) was carried out in each study and results pooled using random effects meta-analysis. Age, sex, body-mass index and diabetes were included as co-variables. Associati…
Incidence, Risk Factors and Outcomes of Submacular Hemorrhage with Loss of Vision in Neovascular Age-Related Macular Degeneration in Daily Clinical P…
2022
Association of lipid-lowering drugs, anti-diabetic drugs, non-steroidal anti-inflammatory drugs, and levodopa with age-related macular degeneration i…
2022
Purpose : Changes in lipid metabolism, chronic inflammation and increased oxidative stress have been discussed as patho-etiogenetic drivers in age-related macular degeneration (AMD). Systemic medication, such as lipid-lowering drugs (LLD) and anti-diabetic drugs, affect these pathways and may therefore also play a role in AMD pathogenesis. We aimed to investigate associations of commonly used systemic drugs with AMD prevalence in the European population.Methods : We included 38,694 adults from 14 population-based studies from the European Eye Epidemiology (E3) consortium. We performed multivariable logistic regression modelling to examine medication use association with prevalence of AMD as…
Rapport scientifique de l'ARVO
2019
Utilisation des antibiotiques en ophtalmologie : merci la sécu
2020
Incidence, Risk Factors and Outcomes of Submacular Hemorrhage with Loss of Vision in Neovascular Age-Related Macular Degeneration in Daily Clinical P…
2023
To evaluate the proportion, baseline predictors, and outcomes of neovascular age-related macular degeneration (nAMD) patients treated with a high burden of vascular endothelial growth factor (VEGF) inhibitor intravitreal injections (IVT) at two years in routine clinical practice. European retrospective data analysis from a prospectively designed observational outcomes registry: the Fight Retinal Blindness! (FRB!) Project. Treatment-naïve eyes (one eye per patient) initiating VEGF inhibitors IVT from January 2017 to March 2020 with 24 months of follow-up, a minimum of 3 injections, and no gap between visits exceeding 365 days were tracked in the registry. We analyzed three treatment burden (…
Imaging and identification of brown adipose tissue on CT scan
2018
International audience
Les valeurs du soin, enjeux éthiques économiques et politiques
2018
International audience; Ce livre invite à réfléchir au système de soins en cherchant à concilier la valeur économique et la valeur intangible du soin. La préservation de la pensée éthique sur le sens du soin est indispensable à l'heure des contraintes gestionnaires.Le monde du soin est structuré et saturé par des valeurs de toutes sortes : celles des professionnels, surtout d'ordre éthique ou scientifique, celles des personnes soignées, d'ordre social, culturel ou familial. La valeur économique est aussi prégnante dans cet univers. Que vaut le soin ? Comment la valeur s'articule-t-elle au coût ? La réponse à ces questions ne se limite pas à déterminer combien coûte le soin. C'est l'ambition…
Impact of type 2 diabetes on depressive-like phenotype and antidepressant response in mice
2013
Abstract at the 17th Annual Meeting of French Society of Pharmacology and Therapeutics, the 80th Annual Meeting of Society of Physiology, the 34th Pharmacovigilance Meeting, the 14th APNET Seminar and the 11th CHU CIC Meeting, 22-24 April 2013, Angers, France.; International audience; Evidence indicates that the prevalence of depression in diabetic subjects is higher than that in the general population. Despite these observations, the mechanisms underpinning the link between metabolic and psychiatric disorders are poorly understood. Moreover, it has been proposed that an impairment of glucose homeostasis may result in blunted antidepressant response to selective serotonin reuptake inhibitor…