Search results for "IRC"

showing 10 items of 5754 documents

Cortisol and trait anxiety as relevant factors involved in memory performance in people with drug-resistant epilepsy

2018

People with drug-resistant epilepsy are exposed to unpredictable and uncontrollable seizures, which can be considered as a chronic stress condition. Additionally, these patients present memory deficits and a high prevalence of depression and anxiety. Cortisol, the main stress hormone, has a modulatory role on memory in healthy individuals and patients with emotional disorders, but its role in memory and emotional processes remains unclear in people with epilepsy. This study analyzes the differences in cortisol levels in people with epilepsy with high and low memory performance, and the relationships among cortisol levels, epilepsy-related factors, memory, anxiety, and depression. Fifty-two …

AdultMaleDrug Resistant EpilepsyHydrocortisoneDrug-resistant epilepsyAnxietyCortisolYoung Adult03 medical and health sciencesBehavioral NeuroscienceEpilepsy0302 clinical medicineMemoryHumansMedicineChronic stress030212 general & internal medicineCircadian rhythmSalivaDepression (differential diagnoses)Memory Disordersbusiness.industryNeuropsychologyArea under the curveMiddle Agedmedicine.diseaseDrug Resistant EpilepsyCircadian RhythmCross-Sectional StudiesNeurologyTrait anxietyAnxietyFemaleNeurology (clinical)medicine.symptombusiness030217 neurology & neurosurgeryClinical psychologyEpilepsy & Behavior
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Assessment of modifications in thickness, curvatures, and volume upon the cornea caused by disposable soft contact lens wear.

2015

Purpose To assess the effect of different disposable soft contact lenses on several corneal parameters–-thickness, anterior and posterior curvature, and volume–-by means of a Scheimpflug imaging-based device (Pentacam HR). Diurnal variations of these parameters were taken into account. Methods Twenty-one young, healthy subjects wore 4 different types of daily disposable soft contact lenses on 4 different days: Dailies AquaComfort Plus, SofLens, Dailies Total1, and Acuvue TruEye. The lenses had different material and water content. Pachymetry and curvature maps and corneal volume values were obtained using the Pentacam HR twice a day: one before putting the lens on and one after an 8-hour pe…

AdultMaleEffects of long-term contact lens wear on the corneaMaterials sciencegenetic structuresCorneal PachymetryScheimpflug principleVisual AcuityCurvatureCorneaYoung AdultOpticsCorneamedicineMyopiaHumansCorneal pachymetryDisposable Equipmentmedicine.diagnostic_testbusiness.industryCorneal TopographyGeneral MedicineOrgan SizeCorneal topographyContact Lenses Hydrophiliceye diseasesCircadian RhythmContact lensOphthalmologymedicine.anatomical_structureFemalesense organsDisposable EquipmentbusinessBiomedical engineeringEuropean journal of ophthalmology
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Estimated radiation exposure of German commercial airline cabin crew in the years 1960-2003 modeled using dose registry data for 2004-2015.

2016

Exposure to ionizing radiation of cosmic origin is an occupational risk factor in commercial aircrew. In a historic cohort of 26,774 German aircrew, radiation exposure was previously estimated only for cockpit crew using a job-exposure matrix (JEM). Here, a new method for retrospectively estimating cabin crew dose is developed. The German Federal Radiation Registry (SSR) documents individual monthly effective doses for all aircrew. SSR-provided doses on 12,941 aircrew from 2004 to 2015 were used to model cabin crew dose as a function of age, sex, job category, solar activity, and male pilots' dose; the mean annual effective dose was 2.25 mSv (range 0.01–6.39 mSv). In addition to an inverse …

AdultMaleEngineeringOperations researchAircraftOccupational riskMean squared prediction errorCrewToxicologyRadiation DosageEffective dose (radiation)Risk Assessment030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineAge DistributionAeronauticsOccupational ExposureRadiation IonizingHumansRegistriesSex DistributionRetrospective Studiesbusiness.industryPublic Health Environmental and Occupational Healthjob-exposure matrixexposure modelingMiddle AgedRadiation Exposure030210 environmental & occupational healthPollutionRadiation exposurePilotsCohortaviationAircrewRegistry dataepidemiologyFemalebusinessionizing radiationCosmic RadiationEnvironmental MonitoringJournal of exposure scienceenvironmental epidemiology
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A correlation linking the predicted mean vote and the mean thermal vote based on an investigation on the human thermal comfort in short-haul domestic…

2015

Abstract The results of an experimental investigation on the human thermal comfort inside the cabin of some Airbus A319 aircrafts during 14 short-haul domestic flights, linking various Italian cities, are presented and used to define a correlation among the predicted mean vote (PMV), a procedure which is commonly used to assess the thermal comfort in inhabited environments, and the equivalent temperature and mean thermal vote (MTV), which are the parameters suggested by the European Standard EN ISO 14505-2 for the evaluation of the thermal environment in vehicles. The measurements of the radiant temperature, air temperature and relative humidity during flights were performed. The air temper…

AdultMaleEngineeringTime FactorsAircraftMeteorologyEquivalent temperaturePhysical Therapy Sports Therapy and RehabilitationHuman Factors and ErgonomicsAbsolute differenceHeatingCorrelationYoung AdultThermalHumansAir ConditioningRelative humiditySafety Risk Reliability and QualityEngineering (miscellaneous)Settore ING-IND/11 - Fisica Tecnica Ambientalebusiness.industryTemperatureThermal comfortConsumer BehaviorMiddle AgedAir conditioningAir temperatureFemalebusinessThermal comfort Aircraft cabins. Air conditioning
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The "exposome" concept - how environmental risk factors influence cardiovascular health.

2019

There is general consensus that environmental pollution and non-chemical stressors contribute to the incidence and prevalence of chronic noncommunicable disease (e.g. cardiovascular, metabolic and mental). Clinical and epidemiological studies support that air pollution and traffic noise are associated with a higher risk for cardiovascular disease and significantly contribute to overall mortality. In this respect, the “exposome” provides a comprehensive description of lifelong exposure history. A recent publication using an updated global exposure-mortality model found that the global all-cause mortality rate attributable to ambient air pollution by PM2.5 and O3 was 8.79 (95% CI 7.11–10.41) …

AdultMaleExposomemedicine.medical_specialtyAdolescentAircraftAir pollutionEnvironmental pollutionDiseasemedicine.disease_causeGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciencesMiceYoung AdultRisk FactorsEnvironmental healthAir PollutionMetals HeavyEpidemiologyMedicineAnimalsHumansChildNoncommunicable DiseasesAgedAged 80 and over0303 health sciencesbusiness.industryMortality rate030302 biochemistry & molecular biologyTraffic noiseStressorInfant NewbornInfantMiddle AgedExposomeCardiovascular DiseasesChild PreschoolFemalebusinessNoiseStress PsychologicalActa biochimica Polonica
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Effects of Fractionated Plasma Separation and Adsorption on Survival in Patients With Acute-on-Chronic Liver Failure

2012

BACKGROUND & AIMS: Fractionated plasma separation and adsorption (FPSA) is an extracorporeal procedure that supports liver function by removing endogenous toxins that cause complications from acute-on-chronic liver failure (AOCLF). We performed a randomized trial to investigate survival of patients with AOCLF treated with FPSA. METHODS: Patients with AOCLF were randomly assigned to groups given a combination of FPSA and standard medical therapy (SMT) (FPSA group, n = 77) or only SMT (SMT group, n = 68). The Prometheus liver support system was used to provide 8 to 11 rounds of FPSA (minimum of 4 hours each) for 3 weeks. Primary end points were survival probabilities at days 28 and 90, irresp…

AdultMaleExtracorporeal Circulationmedicine.medical_specialtyTime FactorsCirrhosismedicine.medical_treatmentMedizinKaplan-Meier EstimateLiver transplantationRisk AssessmentGastroenterologyEnd Stage Liver DiseaseLIVER DISEASELiver diseaseSpontaneous bacterial peritonitisHepatorenal syndromeRisk FactorsInternal medicinemedicineHumansProspective StudiesDialysisProportional Hazards ModelsHepatologybusiness.industryMORTALITYGastroenterologyBilirubinTREATMENTLiver Failure AcuteMiddle Agedmedicine.diseaseEXTRACORPOREAL LIVER SUPPORTSurgeryEuropeTreatment OutcomeFemaleSorption DetoxificationSOFA scoreLiver functionORGAN FAILUREbusinessBiomarkers
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Time‐of‐Day Effect on the Torque and Neuromuscular Properties of Dominant and Non‐Dominant Quadriceps Femoris

2005

The study was conducted first, to determine the possibility of a dichotomy between circadian rhythm of maximal torque production of the knee extensors of the dominant and non-dominant legs, and second, to determine whether the possible dichotomy could be linked to a change in the downward drive of the central nervous system and/or to phenomena prevailing at the muscular level. The dominant leg was defined as the one with which subjects spontaneously kick a football. Tests were performed at 06:00, 10:00, 14:00, 18:00, and 22:00 h. To distinguish the neural and muscular mechanisms that influence muscle strength, the electromyographic and mechanical muscle responses associated with electricall…

AdultMaleFootednessmedicine.medical_specialtyTime FactorsPhysiologyElectromyographyThighBody TemperatureTime of dayPhysiology (medical)Internal medicinemedicineHumansTorqueCircadian rhythmMuscle Skeletalmedicine.diagnostic_testElectromyographybusiness.industryAnatomyElectric StimulationCircadian RhythmPeripheralmedicine.anatomical_structureThighTorqueCardiologymedicine.symptombusinessMuscle ContractionMuscle contractionChronobiology International
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Obtaining a male circumcision prevalence rate of 80% among adults in a short time

2017

Abstract World Health Organization recommends a target for the male circumcision prevalence rate of 80%. This rate will have a substantial impact on the human immunodeficiency virus-acquired immunodeficiency syndrome epidemic in Eastern and Southern Africa. The objective of the study was to assess whether an innovative intervention can lead to an increased voluntary male medical circumcision (VMMC) uptake among adults in a short time. This prospective observational study of a demand generation intervention was conducted in the township of Orange Farm (South Africa) in August to November 2015. In this community male circumcision prevalence rate among adults was stable between 2010 and 2015 a…

AdultMaleGerontologyHealth Knowledge Attitudes PracticeTime Factors4850AdolescentPopulationPsychological interventionPrevalenceObservational StudyDeveloping countryHIV InfectionsHealth PromotionMotivational InterviewingImmunodeficiency SyndromeSouth AfricaYoung Adult03 medical and health sciences0302 clinical medicinepreventionEnvironmental healthPrevalencemale circumcisionHumansMedicineProspective Studies030212 general & internal medicineYoung adultProspective cohort studyeducationeducation.field_of_study030505 public healthbusiness.industrypublic healthdemand creationHIVGeneral MedicineMiddle AgedPatient Acceptance of Health CareCircumcision MaleuptakeAfricaObservational study0305 other medical sciencebusinessResearch ArticleMedicine
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Physical inactivity and obesity: A vicious circle.

2008

OBJECTIVE: Physical activity (PA) begins to decline in adolescence with a concomitant increase in weight. We hypothesized that a vicious circle may arise between decreasing PA and weight gain from adolescence to early adulthood. METHODS AND PROCEDURES: PA and self-perceived physical fitness assessed in adolescents (16-18 years of age) were used to predict the development of obesity (BMI > or =30 kg/m(2)) and abdominal obesity (waist >/=88 cm in females and > or =102 cm in males) at age 25 in 4,240 twin individuals (90% of twins born in Finland, 1975-1979). Ten 25-year-old monozygotic (MZ) twin pairs who were discordant for obesity (with a 16 kg weight difference) were then carefull…

AdultMaleGerontologymedicine.medical_specialtyAdolescentEndocrinology Diabetes and MetabolismPhysical activityMedicine (miscellaneous)physical activity030209 endocrinology & metabolismMotor ActivityliikuntaArticleCohort Studies03 medical and health sciences0302 clinical medicineEndocrinologyPredictive Value of TestsRisk FactorsInternal medicineEarly adulthoodmedicineHumansLongitudinal StudiesObesity030212 general & internal medicineLife StyleNutrition and Dieteticsbusiness.industryBody WeightTwins Monozygoticmedicine.diseaseObesityTwin studyVirtuous circle and vicious circle3. Good healthEndocrinologyPredictive value of testslihavuusFemaleBasal Metabolismmedicine.symptomEnergy MetabolismbusinessWeight gainCohort study
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A new heart rate variability-based method for the estimation of oxygen consumption without individual laboratory calibration: Application example on …

2008

Traditionally, the estimation of oxygen consumption (VO2) at work using heart rate (HR) has required the determination of individual HR/VO2 calibration curves in a separate exercise test in a laboratory (VO2-TRAD). Recently, a new neural network-, and heart rate variability-based method has been developed (Firstbeat PRO heartbeat analysis software) for the estimation of VO2 without individual calibration (VO2-HRV). In the present study, the VO2-values by the VO2-HRV were compared with the values by VO2-TRAD in 22 postal workers. Within individuals the correlation between the two methods was high (range 0.80-0.99). The VO2-TRAD gave higher values of VO2 compared to VO2-HRV (19%) especially d…

AdultMaleHeartbeatCalibration curveCalibration (statistics)Physical Therapy Sports Therapy and RehabilitationHuman Factors and ErgonomicsCorrelationOxygen ConsumptionHeart RateStatisticsHeart rateRange (statistics)HumansHeart rate variabilityPostal ServiceSafety Risk Reliability and QualityEngineering (miscellaneous)FinlandSimulationMathematicsEstimationmusculoskeletal neural and ocular physiologyMiddle AgedFemaleEnergy Metabolismhuman activitiescirculatory and respiratory physiologyApplied Ergonomics
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