Search results for "LOCATIONS"

showing 10 items of 301 documents

The GABAergic System and the Gastrointestinal Physiopathology.

2015

Since the first report about the presence of γ-aminobutyric acid (GABA) within the gastrointestinal (GI) tract, accumulating evidence strongly supports the widespread representation of the GABAergic system in the enteric milieu, underlining its potential multifunctional role in the regulation of GI functions in health and disease. GABA and GABA receptors are widely distributed throughout the GI tract, constituting a complex network likely regulating the diverse GI behaviour patterns, cooperating with other major neurotransmitters and mediators for maintaining GI homeostasis in physiologic and pathologic conditions. GABA is involved in the circuitry of the enteric nervous system, controlling…

GABA AgentsGastrointestinal DiseasesPharmacologyBiologySettore BIO/09 - FisiologiaEnteric Nervous Systemgamma-Aminobutyric acidgaba enteric neuronParacrine signallingImmune systemReceptors GABAparasitic diseasesDrug DiscoverymedicineAnimalsHumansMolecular Targeted Therapygamma-Aminobutyric AcidPharmacologyGABAA receptorVisceral painsocial sciencesGastrointestinal TractGABA AgentsDrug Designpopulation characteristicsGABAergicEnteric nervous systemmedicine.symptomhuman activitiesNeurosciencegeographic locationsmedicine.drug
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Genetic structure and demographic inference of the regular sea urchin Sterechinus neumayeri (Meissner, 1900) in the Southern Ocean: the role of the l…

2018

22 pages; International audience; One of the most relevant characteristics of the extant Southern Ocean fauna is its resiliency to survive glacial processes of the Quaternary. These climatic events produced catastrophic habitat reductions and forced some marine benthic species to move, adapt or go extinct. The marine benthic species inhabiting the Antarctic upper continental shelf faced the Quaternary glaciations with different strategies that drastically modified population sizes and thus affected the amount and distribution of intraspecific genetic variation. Here we present new genetic information for the most conspicuous regular sea urchin of the Antarctic continental shelf, Sterechinus…

Gene FlowTopographyHeredityEcological MetricsPopulation geneticsOceans and SeasGenetic locilcsh:MedicineDNA MitochondrialGeographical LocationsBodies of waterOceansGeneticsAnimalslcsh:ScienceEcosystemSpecies diversityPopulation DensityIslandsEvolutionary BiologyLandforms[SDV.GEN.GPO]Life Sciences [q-bio]/Genetics/Populations and Evolution [q-bio.PE]Population BiologyGeographyEcologylcsh:REcology and Environmental SciencesBiology and Life SciencesGeomorphologyBayes TheoremMarine and aquatic sciencesGenetic MappingPhylogeographyAntarctic OceanGenetics PopulationBiogeographyHaplotypesSea UrchinsPeople and PlacesEarth SciencesAntarcticalcsh:QResearch Article
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Mediterranean diet adherence and synergy with acute myocardial infarction and its determinants: A multicenter case-control study in Italy

2018

Background Cardiovascular diseases are the leading causes of mortality and morbidity in Western countries. The possible synergistic effect of poor adherence to a Mediterranean diet (MD) and other risk factors for acute myocardial infarction (AMI) such as hypertension, cholesterol, ever smoker, BMI> 25, diabetes, has not been deeply studied. Design Case-control study. Methods Patients with first AMI and controls from four tertiary referral Italian centers were screened for enrolment. Dietary information was collected through a questionnaire and a MD adherence score was calculated. Physical activity and smoking habits were also registered. The Synergy Index was calculated according to Rothman…

Genetics and Molecular Biology (all)MaleMultivariate analysisMediterranean dietTertiary Care CenterMyocardial Infarctionlcsh:MedicineBlood PressureMediterranean030204 cardiovascular system & hematologyPathology and Laboratory MedicineDiet MediterraneanVascular MedicineBiochemistryGeographical locationsTertiary Care CentersHabitschemistry.chemical_compoundEndocrinology0302 clinical medicineRisk FactorsSurveys and QuestionnairesMedicine and Health SciencesSmoking HabitsSurveys and Questionnaire030212 general & internal medicineMyocardial infarctionlcsh:ScienceMultidisciplinarySmokingMiddle AgedEuropeHyperlipidemiaItalyResearch DesignSettore MED/42HypertensionFemaleCase-Control StudieHumanResearch Articlemedicine.medical_specialtyAged; Case-Control Studies; Feeding Behavior; Female; Humans; Hypertension; Italy; Male; Middle Aged; Myocardial Infarction; Risk Factors; Smoking; Surveys and Questionnaires; Tertiary Care Centers; Diet Mediterranean; Patient ComplianceReferralEndocrine DisordersSmoking habitHypercholesterolemiaCardiologyResearch and Analysis Methods03 medical and health sciencesSigns and SymptomsDiagnostic MedicineDiabetes mellitusInternal medicineDiabetes MellitusAged; Case-Control Studies; Feeding Behavior; Female; Humans; Hypertension; Italy; Male; Middle Aged; Myocardial Infarction; Risk Factors; Smoking; Surveys and Questionnaires; Tertiary Care Centers; Diet Mediterranean; Patient Compliance; Biochemistry Genetics and Molecular Biology (all); Agricultural and Biological Sciences (all)medicineHumansEuropean UnionNutritionAgedBehaviorCholesterolbusiness.industryRisk Factorlcsh:RCase-control studyBiology and Life SciencesFeeding Behaviormedicine.diseaseDietAgricultural and Biological Sciences (all)chemistryMetabolic DisordersCase-Control StudiesPatient Compliancelcsh:QPeople and placesbusinessPLOS ONE
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Factors associated with first- versus second-generation long-acting antipsychotics prescribed under ordinary clinical practice in Italy

2018

Background For many years, long-acting intramuscular (LAI) antipsychotics have been prescribed predominantly to chronic and severe patients, as a last resort when other treatments failed. Recently, a broader and earlier use of LAIs, particularly second-generation LAIs, has been emphasized. To date, few studies attempted to frame how this change in prescribing took place in real-world practice. Therefore, this study aimed to describe the clinical features of patients prescribed with LAIs, and to explore possible prescribing differences between first- and second-generations LAIs under ordinary clinical practice in Italy. Methods The STAR Network "Depot" Study is an observational, longitudinal…

Genetics and Molecular Biology (all)MalePediatricsEuropean PeopleBipolar DisorderCross-sectional studyEconomicsEpidemiologymedicine.medical_treatmentassessmentviruseslcsh:MedicineSocial SciencesLongitudinal StudieBiochemistryPrescriptionGeographical locations0302 clinical medicineMathematical and Statistical TechniquesBiochemistry Genetics and Molecular Biology (all); Agricultural and Biological Sciences (all)immune system diseasesEpidemiologyMedicine and Health Scienceslong-acting intramuscular (LAI) antipsychotics; clinical practice; assessment; second-generation antipsychotic (SGA) LAIsAntipsychoticsEthnicitiesLongitudinal Studieslcsh:ScienceMultidisciplinaryvirus diseasesDrugsMiddle Agedclinical practiceItalian PeopleEuropePrescriptionsItalyPhysical SciencesAripiprazoleFemaleBivariate AnalysisStatistics (Mathematics)medicine.drugHumanResearch ArticleAntipsychotic AgentsEmploymentAdultmedicine.medical_specialtyAdolescentResearch and Analysis Methods03 medical and health sciencesMental Health and PsychiatrymedicineHumansPaliperidoneBipolar disorderEuropean UnionStatistical MethodsAntipsychoticCross-Sectional StudiePharmacologyRisperidoneBiochemistry Genetics and Molecular Biology (all)business.industryMood Disorderslcsh:Rmedicine.disease030227 psychiatryAntipsychotic AgentCross-Sectional StudiesAgricultural and Biological Sciences (all)Labor EconomicsMultivariate AnalysisSchizophreniaObservational studylcsh:QPopulation Groupingslong-acting intramuscular (LAI) antipsychoticsPeople and placesbusiness030217 neurology & neurosurgerysecond-generation antipsychotic (SGA) LAIsMathematicsPLoS ONE
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Development of cytoplasmically incompatible and integrated (translocated incompatible) strains ofCulex pipiens fatigans for use in genetic control

1976

Crosses were made between strains of the Culex pipiens complex to select and develop strains with suitable cytoplasmic incompatibility properties for use in field experiments in genetic control of Culex pipiens fatigans near Delhi, India.

GeneticsCulex pipiens fatigansvirusesparasitic diseasesfungiBotanyGeneticsvirus diseasesCulex pipiens complexBiologygeographic locationsCytoplasmic incompatibilityJournal of Genetics
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Random amplified polymorphic DNA (RAPD) markers detect a single phenotype in Lysimachia minoricensis J.J. Rodr. (Primulaceae), a wild extinct plant

2000

Lysimachia minoricensis is a Mediterranean (Balearic Islands) endemic that is extinct in the wild but extant in botanical gardens. Previously, no variation at 22 isozyme loci was revealed in more than 150 analysed plants. Random amplified polymorphic DNA (RAPD) analysis was used to examine genetic variation among five individuals from each of eight botanical garden accessions (40 plants). No polymorphisms were detected at 201 amplified bands. This is the first report of RAPD monomorphism in a nonapomictic vascular plant. The lack of detectable genetic variation suggests that an extremely reduced gene pool was recovered in the field before its extinction. Although the screening of other geno…

GeneticsMonomorphismbiologyExtinct in the wildfood and beveragesLysimachia minoricensisbiology.organism_classificationEx situ conservationRAPDPrimulaceaeGenetic variationGeneticsGene poolgeographic locationsEcology Evolution Behavior and SystematicsMolecular Ecology
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Polybrominated methoxy diphenyl ethers (MeO-PBDEs) in fish and guillemot of Baltic, Atlantic and Arctic environments

2003

Arctic cod liver samples from Vestertana Fjord at the Arctic coast of Norway, salmon and guillemot samples from the Baltic Sea and the Atlantic Ocean, and salmon and lamprey larva samples from Kymijoki River in southern Finland were analysed for the occurrence of tri-, tetra- and pentabromomethoxy diphenyl ethers and their concentration levels were estimated. These compounds have previously been identified by other research groups in salmon, seal and dolphin samples. The aim of this study was to find out a possible temporal trend in the concentrations of these compounds in the cod liver samples from years 1987-1998 and to investigate the possible spatial differences in the concentrations in…

Geologic SedimentsBoreogadus saidaHealth Toxicology and Mutagenesis010501 environmental sciences01 natural scienceschemistry.chemical_compoundPolybrominated diphenyl ethersTissue DistributionAtlantic OceanFlame Retardantsgeography.geographical_feature_categorybiologyPhenyl EthersFishesBiotaBiodiversityGeneral MedicinePollutionOceanographyLiverLarvaEnvironmental chemistrygeographic locationsEnvironmental MonitoringEnvironmental EngineeringOceans and SeasPolybrominated BiphenylsFjordHydroxylationRiversUria aalgeAnimalsEnvironmental Chemistry14. Life underwater0105 earth and related environmental sciencesgeographyHydrocarbons HalogenatedIcefungi010401 analytical chemistryDiphenyl etherPublic Health Environmental and Occupational HealthGeneral ChemistryGadidaebiology.organism_classification0104 chemical sciencesArcticchemistry13. Climate actionEnvironmental scienceWater Pollutants ChemicalChemosphere
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Effects of aquaculture waste feeds and antibiotics on marine benthic ecosystems in the Mediterranean Sea

2022

Intensive aquaculture is an important source of organic waste and antibiotics into the marine environment. Yet, their impacts on benthic marine ecosystems are poorly understood. Here, we investigated the ecological impacts of fish feed waste alone and in combination with three different antibiotics (i.e., oxytetracycline, florfenicol and flumequine) in benthic ecosystems of the Mediterranean Sea by performing a field experiment. We assessed the fate of the antibiotics in the sediment and their accumulation in wild fauna after two weeks of exposure. Moreover, we investigated the impact of the feed waste alone and in combination with the antibiotics on sediment physico-chemical properties, on…

Geologic SedimentsEnvironmental EngineeringFaunaAquacultureCommercial fish feedMarine pollutionMediterranean seaAquacultureMediterranean SeamedicineAnimalsHumansEnvironmental ChemistryMarine ecosystemWaste Management and DisposalEcosystembusiness.industryfungiQ Science (General)BiodiversityPollutionAnti-Bacterial AgentsFisheryBenthic zoneFlumequineEnvironmental sciencebusinessWater Pollutants Chemicalgeographic locationsEnvironmental Monitoringmedicine.drug
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Testing and comparing two self-care-related instruments among older Chinese adults

2017

Objectives The study aimed to test and compare the reliability and validity, including sensitivity and specificity of the two self-care-related instruments, the Self-care Ability Scale for the Elderly (SASE), and the Appraisal of Self-care Agency Scale-Revised (ASAS-R), among older adults in the Chinese context. Methods A cross-sectional design was used to conduct this study. The sample consisted of 1152 older adults. Data were collected by a questionnaire including the Chinese version of SASE (SASE-CHI), the Chinese version of ASAS-R (ASAS-R-CHI) and the Exercise of Self-Care Agency scale (ESCA). Homogeneity and stability, content, construct and concurrent validity, and sensitivity and spe…

GerontologyMaleAgingResearch ValidityPhysiologylcsh:MedicineGeographical LocationsHabitsElderlySurveys and QuestionnairesStatisticsContent validityMedicine and Health SciencesMedicineEthnicitieslcsh:ScienceGeriatricsCognitive ImpairmentAged 80 and overMultidisciplinary030504 nursingCognitive Neurology030503 health policy & servicesResearch AssessmentMiddle AgedNeurologyFemale0305 other medical scienceResearch Articlemedicine.medical_specialtyChinaAsiaCorrelation coefficientPsychometricsCognitive NeuroscienceConcurrent validityResearch and Analysis MethodsSensitivity and Specificity03 medical and health sciencesCronbach's alphaHumansRank correlationAgedBehaviorReceiver operating characteristicbusiness.industrylcsh:RConstruct validityBiology and Life SciencesReproducibility of ResultsSelf CareCross-Sectional StudiesAge GroupsGeriatricsPeople and PlacesCognitive Sciencelcsh:QPopulation GroupingsbusinessPhysiological ProcessesOrganism DevelopmentChinese PeopleNeuroscienceDevelopmental BiologyPLoS ONE
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Changes in smoking prevalence among first- and second-generation Turkish migrants in Germany – an analysis of the 2005 Microcensus

2009

Abstract Background Compared to the majority population of a host country, migrants tend to have different health risks and health behaviour. We have hypothesised that these differences diminish with time passed since migration. We tested this hypothesis by examining smoking behaviour among Turkish migrants and their children born in Germany (second-generation migrants), stratified by educational level and, for the first generation, length of residence. Methods We estimated the prevalence of smoking based on the representative 2005 Mikrozensus, an annual survey including 1% of Germany's households. The 2005 Microcensus was the first to provide information that makes it possible to different…

Gerontologymedicine.medical_specialtyTurkishmedia_common.quotation_subjectImmigrationPopulation610medicineeducationHealth policySocial policymedia_commoneducation.field_of_studybusiness.industrylcsh:Public aspects of medicineResearchHealth PolicyPublic healthPublic Health Environmental and Occupational HealthHealth services researchlcsh:RA1-1270social scienceslanguage.human_languagelanguagepopulation characteristicsResidencebusinessgeographic locationsDemographyInternational Journal for Equity in Health
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