Search results for "Licata"
showing 10 items of 4432 documents
The electric properties of ionic solutions: a molecular dynamics (preliminary) study
2011
Curcumin and Andrographolide Co-Administration Safely Prevent Steatosis Induction and ROS Production in HepG2 Cell Line
2023
Non-alcoholic fatty liver disease (NAFLD) is an emerging chronic liver disease worldwide. Curcumin and andrographolide are famous for improving hepatic functions, being able to reverse oxidative stress and release pro-inflammatory cytokines, and they are implicated in hepatic stellate cell activation and in liver fibrosis development. Thus, we tested curcumin and andrographolide separately and in combination to determine their effect on triglyceride accumulation and ROS production, identifying the differential expression of genes involved in fatty liver and oxidative stress development. In vitro steatosis was induced in HepG2 cells and the protective effect of curcumin, andrographolide, and…
Dynamics of supercooled confined water measured by deep inelastic neutron scattering
2017
In this paper, we present the results of deep inelastic neutron scattering (DINS) measurements on supercooled water confined within the pores (average pore diameter ~ 20 Ã ) of a disordered hydrophilic silica matrix obtained through hydrolysis and polycondensation of the alkoxide precursor Tetra-Methyl-Ortho-Silicate via the sol-gel method. Experiments were performed at two temperatures (250 K and 210 K, i.e., before and after the putative liquidâliquid transition of supercooled confined water) on a âwetâ sample with hydration h ~ 40% w/w, which is high enough to have water-filled pores but low enough to avoid water crystallization. A virtually âdryâ sample at h ~ 7% was also inve…
Experimental evidence for a liquid-liquid crossover in deeply cooled confined water.
2014
International audience; In this work we investigate, by means of elastic neutron scattering, the pressure dependence of mean square displacements (MSD) of hydrogen atoms of deeply cooled water confined in the pores of a three-dimensional disordered SiO 2 xerogel; experiments have been performed at 250 and 210 K from atmospheric pressure to 1200 bar. The " pressure anomaly " of supercooled water (i.e., a mean square displacement increase with increasing pressure) is observed in our sample at both temperatures; however, contrary to previous simulation results and to the experimental trend observed in bulk water, the pressure effect is smaller at lower (210 K) than at higher (250 K) temperatur…
The boson peak of deeply cooled confined water reveals the existence of a low-temperature liquid-liquid crossover.
2014
International audience; The Boson peak of deeply cooled water confined in the pores of a silica xerogel is studied by inelastic neutron scattering at different hydration levels to separate the contributions from matrix, water on the pore surfaces and "internal" water. Our results reveal that at high hydration level, where the contribution from internal water is dominant, the temperature dependence of the Boson peak intensity shows an inflection point at about 225 K. The complementary use of differential scanning calorimetry to describe the thermodynamics of the system allows identifying the inflection point as the signature of a water liquid-liquid crossover.
Sn-Co Nanowires: High-Performing Electrodes as Anodes for Lithium-ion Batteries
2012
Coffee Restores Expression of lncRNAs Involved in Steatosis and Fibrosis in a Mouse Model of NAFLD
2021
Background and aim: Coffee intake exerts protective effects against non-alcoholic fatty liver disease (NAFLD), although without fully cleared mechanisms. In this study we aimed to assess whether coffee consumption may influence the expression of long non-coding RNAs (lncRNAs) in the liver. Methods: C57BL/6J mice were fed a 12-week standard diet (SD), high-fat diet (HFD) or HFD plus decaffeinated coffee solution (HFD + coffee). Expression of specific lncRNAs involved in NAFLD was analyzed by real-time PCR. For the most differentially expressed lncRNAs, the analysis was also extended to their mRNA targets. Results: Decaffeinated coffee intake reduced body weight gain, prevented NAFLD, lowered…
Banks and Territory: Investigation in Knowledge and Building New Relationships between Territorial Banks and Local Actors
2014
A series of events in the late 1980s, such as the process of market globalization, the birth of virtual economy, the decrease in interest rates, made banks develop a sort of schizophrenic view of the market: on one side, in a scenario of globalization, they wanted to have contacts with international markets, in a logic which should have put an end to the geography of markets (R. O’Brien 1992); on the other side, during the 1990s, banks felt there were strong information asymmetries between suppliers and beneficiaries of funds. Because these asymmetries increased with geographical distance, banks felt the need to specialize and find their own place in the territory or, in other words, the ne…
Advanced characterization of a fully human IgG1 therapeutic monoclonal antibody by structure-activity relationship studies
2021
Homage to Proserpina, or: why did the charophytes of the Pergusa Lake vanish?
2020
An important bisexual population of the charophyte Chara canescens Loisel. (Characeae, Charales, Charophyceae) was reported in the XIX century for the Pergusa Lake (Sicily). A recent field survey to check its presence revealed that it has disappeared. After a bibliographic research to understand when and why this happened, the input of freshwater from outside the basin and the introduction of the carps were identified as the two main causes for its recent extinction. Some possible management measures to try to restore the lake ecosystem are proposed.