Search results for "MIME"
showing 10 items of 311 documents
Advances in Research for Biomimetic Materials
2018
Smart surfaces and materials can play a significant role in intelligent, adaptive and responsive envelopes because of these intrinsic properties. The environmental question and energy efficiency in which the construction sector is involved, is in a process that can not be interrupted and that puts researchers and designers in front of a scientific and design challenge in which it is necessary to contribute to find different ways of study and experimentation on new materials and constructive languages, ranging from the application, to the structural, design and molecular, to mention the main ones. The development of technologies is helping architects of the “biomimetic current” to recreate c…
Innovative Applications and Experiments for the Protection of Archaeological Sites
2020
Nowadays, the protection in situ, the enhancement and the fruition of archaeological sites are issues that are even more relevant, if we take into account the effects caused, in recent decades, by climate change both on the conservation of the most fragile artefacts and on the well-being of visitors. New questions related to the ‘recover of identity’ are raised by the relationships that the protection interventions establish with the environmental context (external) and with the ancient ruins (internal), imposing an interpretation of the project as a union of landscape, morphological, climatic, technical, use and management aspects, or by requiring a holistic and integrated approach, from a…
Astrazione e mimesi nella rappresentazione digitale
2013
La rappresentazione piana si è espressa, da sempre, per mezzo di registri oscillanti tra forme espressive mimetiche e forme astratte. A ben vedere sembrerebbe che la comunicazione, in questo come in altri campi, insegua, da un lato, la necessità dell’uomo di riprodurre il mondo conosciuto imitandone le caratteristiche, dall’altro, di comporre il sintagma espressivo in modo da comunicare concetti, idee, senza cercare di riprodurre il mondo reale, ma con la volontà di trasmettere un pensiero. Non è corretto, però, pensare che la separazione tra il codice mimetico e quello astratto e simbolico sia sempre così evidente. IL saggio vuole dimostrare come anche la rappresentazione digitale si muova…
La musica di tradizione orale
2013
Il testo offre una rassegna delle forme, dei contesti e degli strumenti musicali che caratterizzano la musica di tradizione orale in Sicilia, prestando particolare alla dimensione linguistica e ai valori socioantropologici.
Apposition of silica lamellae during growth of spicules in the demosponge Suberites domuncula: Biological/biochemical studies and chemical/biomimetic…
2006
Recently it has been discovered that the formation of the siliceous spicules of Demospongiae proceeds enzymatically (via silicatein) and occurs matrix guided (on galectin strings). In addition, it could be demonstrated that silicatein, if immobilized onto inorganic surfaces, provides the template for the synthesis of biosilica. In order to understand the formation of spicules in the intact organism, detailed studies with primmorphs from Suberites domuncula have been performed. The demosponge spicules are formed from several silica lamellae which are concentrically arranged around the axial canal, harboring the axial filament composed of silicatein. Now we show that the appositional growth o…
Polynucleotide differentiation using hybrid solid-state nanopore functionalizing with α-hemolysin
2019
We report results from full atomistic molecular dynamics simulations on the properties of biomimetic nanopores. This latter result was obtained through the direct insertion of an α-hemolysin protein inside a hydrophobic solid-state nanopore. Upon translocation of different DNA strands, we demonstrate here that the theoretical system presents the same discrimination properties as the experimental one obtained previously. This opens an interesting way to promote the stability of a specific protein inside a solid nanopore to develop further biomimetic applications for DNA or protein sequencing.
Chemoenzymatic Synthesis of Functional Sialyl LewisX Mimetics with a Heteroaromatic Core
2014
Functional mimetics of the sialyl Lewis(X) tetrasaccharide were prepared by the enzymatic sialylation of a 1,3-diglycosylated indole and a glycosyl azide, which was subsequently transformed into a 1,4-diglycosylated 1,2,3-triazole, by using the trans-sialidase of Trypanosoma cruzi. These compounds inhibited the binding of E-, L-, and P-selectin-coated nanoparticles to polyacrylamide-bound sialyl-Lewis(X) -containing neighboring sulfated tyrosine residues (sTyr/sLe(X) -PAA) at low or sub-millimolar concentrations. Except for E-selectin, the mimetics showed higher activities than the natural tetrasaccharide.
Syntheses, X-ray structures, and physicochemical properties of phenoxo-bridged dinuclear nickel(II) complexes: kinetics of transesterification of 2-h…
2009
Four dinuclear nickel(II) complexes [Ni(II)(2)(L(1))(O(2)CMe)(2)(H(2)O)(2)][PF(6)].MeOH.3H(2)O (1), [Ni(II)(2)(L(1))(O(2)CMe)(2)(NCS)] (2), [Ni(II)(2)(L(2))(O(2)CMe)(2)(MeOH)(H(2)O)][ClO(4)] (3), and [Ni(II)(2)(L(2))(O(2)CMe)(2)(MeOH)(H(2)O)][BPh(4)].3MeOH.H(2)O (4) have been synthesized [HL(1): 2,6-bis[N-methyl-N-(2-pyridylethyl)amino]-4-methylphenol; HL(2): 2,6-bis[3-(pyridin-2-yl)pyrazol-1-ylmethyl]-4-methylphenol]. Complexes 1, 3, and 4 are new while complex 2 was reported previously by Fenton and co-workers (the structure of 2 was presented but no physicochemical properties of this complex were reported; in this work such studies have been completed). X-ray crystallographic analyses of…
Visualization of RNA-Quadruplexes in Live Cells
2015
Visualization of DNA and RNA quadruplex formation in human cells was demonstrated recently with different quadruplex-specific antibodies. Despite the significant interest in these immunodetection approaches, dynamic detection of quadruplex in live cells remains elusive. Here, we report on NaphthoTASQ (N-TASQ), a next-generation quadruplex ligand that acts as a multiphoton turn-on fluorescent probe. Single-step incubation of human and mouse cells with N-TASQ enables the direct detection of RNA-quadruplexes in untreated cells (no fixation, permeabilization or mounting steps), thus offering a unique, unbiased visualization of quadruplexes in live cells.
Dynamics of Pattern Formation in Biomimetic Systems
2008
This paper is an attempt to conceptualize pattern formation in self-organizing systems and, in particular, to understand how structures, oscillations or waves arise in a steady and homogenous environment, a phenomenon called symmetry breaking. The route followed to develop these ideas was to couple chemical oscillations produced by Belousov-Zhabotinsky reaction with confined reaction environments, the latter being an essential requirement for any process of Life. Special focus was placed on systems showing organic or lipidic compartments, which represent more reliable biomimetic matrices.