Search results for "Manuscript"

showing 10 items of 119 documents

Immunoproteasome LMP2 60HH Variant Alters MBP Epitope Generation and Reduces the Risk to Develop Multiple Sclerosis in Italian Female Population

2010

BackgroundAlbeit several studies pointed out the pivotal role that CD4+T cells have in Multiple Sclerosis, the CD8+ T cells involvement in the pathology is still in its early phases of investigation. Proteasome degradation is the key step in the production of MHC class I-restricted epitopes and therefore its activity could be an important element in the activation and regulation of autoreactive CD8+ T cells in Multiple Sclerosis.Methodology/principal findingsImmunoproteasomes and PA28-alphabeta regulator are present in MS affected brain area and accumulated in plaques. They are expressed in cell types supposed to be involved in MS development such as neurons, endothelial cells, oligodendroc…

MaleT cells proteasomes multiple sclerosis parietal lobeMuscle ProteinsImmunoproteasomeEpitopeEpitopesGene FrequencyRisk FactorsCytotoxic T cellFunding: This work was financed in part by the grant Giovani Ricercatori 2007 from Italian Ministry of Health to MM DG and FMB by a grant from the European Commission Integrated Project PROTEOMAGE (FP6) to CF by the finalized projects of Fondazione Italiana Sclerosi Multipla (FISM) cod. 2003/R26 and BioPharmaNet to CF and 2002/R/40 and 2005/R/10 2008/R/11 (Genoa) to SD'A by the University of Bologna (FRO) to MPF by the Regione Piemonte (Ricerca Sanitaria Finalizzata Project and Ricerca Sanitaria Applicata-CIPE Project) to SD'A by Associazione Amici del Centro Dino Ferrari and IRCCS Ospedale Maggiore Policlinico Milano to DG and by the grants Sonderforschungsbereich (SFB-507 SFB-421) to PMK and US the grants TR43 and Neurocure to PMK. MM benefited from the A.V. Humboldt PostDoc fellowship. The funders had no role in study design data collection and analysis decision to publish or preparation of the manuscript.MultidisciplinaryMicrogliaQRBrainMiddle AgedImmunohistochemistryCysteine EndopeptidasesOligodendrogliamedicine.anatomical_structureItalyImmunoproteasome; multiple sclerosis; italian populationmultiple sclerosiImmunology/Antigen Processing and RecognitionMedicineFemaleMicrogliaNeuroscience/Neurobiology of Disease and RegenerationResearch ArticleProtein BindingAdultProteasome Endopeptidase ComplexMultiple SclerosisGenotypeScienceMolecular Sequence DataImmunology/AutoimmunityBiologySex FactorsMHC class IHLA-A2 AntigenmedicineHumansAmino Acid SequenceAlleleHLA-A AntigensMultiple sclerosisMacrophagesMyelin Basic Proteinmedicine.diseaseMyelin basic proteinImmunologybiology.proteinitalian populationCD8PLoS ONE
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The Pomar Codex (ca, 1590): plants and animals of the old world and from the Hernandez expedition to America.

1992

Abstract<title> RIASSUNTO </title>Si descrive un codice illustrato (ca. 1590), donato dal re Filippo II a Honorato Pomar, professore di medicina botanica all'Università di Valencia, e ora conservato nella biblioteca della stessa universita. Tale codice contiene 218 acquarelli di piante e animali del Vecchio Continente e provenienti dalla spedizione nelle Americhe di Hernandez (1571-1577). Inoltre, l'articolo si sofferma brevemente sull'interesse di Filippo II per la storia naturale, sulla spedizione di Hernandez e sulla cattedra di botanica medica all'universita di Valencia nel corso del sedicesimo secolo. Infine, si discute dell'identita dell'autore delle illustrazioni e dei te…

Manuscripts as TopicHistory and Philosophy of ScienceSpainmedia_common.quotation_subjectHistory Early Modern 1451-1600History Modern 1601-Medical IllustrationBotanyArtHumanitiesmedia_commonNuncius
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De Platonis "Parmenidis" codicibus quaestiones

2021

Si fa un censimento completo dei manoscritti che contengono il "Parmenide" di Platone e se ne definiscono i rapporti, proponendo innovazioni e integrazioni rispetto agli studi di C. Moreschini (1965-66). A complete census is made of the manuscripts that contain Plato's "Parmenides" and their relationships are defined, proposing innovations and additions with respect to the studies of C. Moreschini (1965-66).

Manuscripts Platonic tradition ParmenidesSettore L-FIL-LET/05 - Filologia Classica
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La tradizione manoscritta del centone di Proba

2014

Manuscripts textual criticism Latin poetry
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La participación de la Universitat de València en el proyecto Europeana Regia

2013

En este artículo se describe la participación de la Universitat de València en el proyecto Europeana Regia: biblioteca digital de manuscritos medievales y renacentistas, coordinado por la Bibliothèque Nationale de France y cofinanciado por la Comisión Europea. También se detalla la integración del proyecto dentro de los objetivos de la institución: la creación de una colección digital propia destinada a la investigación y la incorporación de los manuscritos digitalizados en el repositorio institucional. Se describen los resultados teóricos y prácticos del proyecto: work packages, página web etc. Finalmente se detalla cómo un año después de ejecutado el proyecto los manuscritos de la Univers…

Manuscritos medievalesDigital LibraryEuropeana RegiaBiblioteca digital:CIENCIAS TECNOLÓGICAS::Otras especialidades tecnológicas [UNESCO]RepositoriesRepositoriosRenaissance ManuscriptsMedieval ManuscriptsUNESCO::CIENCIAS TECNOLÓGICAS::Otras especialidades tecnológicasManuscritos renacentistasUniversitat de València
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Il contributo di Marsilio Ficino al testo di Ermia neoplatonico e l'esemplare greco da lui utilizzato

2010

Marsilius Ficinus manuscripts emendations
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The Effects of Acceptance and Commitment Therapy (ACT) Intervention on Inflammation and Stress Biomarkers : a Randomized Controlled Trial

2020

Abstract Background Psychological processes can be manifested in physiological health. We investigated whether acceptance and commitment therapy (ACT), targeted on psychological flexibility (PF), influences inflammation and stress biomarkers among working-age adults with psychological distress and overweight/obesity. Method Participants were randomized into three parallel groups: (1) ACT-based face-to-face (n = 65; six group sessions led by a psychologist), (2) ACT-based mobile (n = 73; one group session and mobile app), and (3) control (n = 66; only the measurements). Systemic inflammation and stress markers were analyzed at baseline, at 10 weeks after the baseline (post-intervention), and…

MindfulnessPsychological interventionbiomarkkeritOverweightAcceptance and commitment therapylaw.inventionjoustavuus0302 clinical medicineMARKERSRandomized controlled triallawWeight lossPsychology030212 general & internal medicinePsychological flexibilityApplied Psychologytietoinen läsnäolotulehdusEATING BEHAVIORylipainoPUBLIC-HEALTH PRACTICEpsykofysiologia3. Good healthHealth psychologyMINDFULNESS-BASED INTERVENTIONCARDIOVASCULAR-DISEASE/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingmedicine.symptomMindfulnessAdultmedicine.medical_specialty515 Psychologyhyväksymis- ja omistautumisterapiaPERCEIVED STRESSWEIGHT-LOSSLow-grade inflammationStressFull Length Manuscript03 medical and health sciencesSDG 3 - Good Health and Well-beingInternal medicineNORDIC DIETPost-hoc analysismedicineHumansObesityAcceptance and Commitment TherapyInflammationPsykologibusiness.industryCORTISOLstressiOverweightACTPHYSICAL-ACTIVITY3111 BiomedicinebusinessBiomarkers030217 neurology & neurosurgeryfysiologiset vaikutukset
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Prevalence of HPV infection in racial-ethnic subgroups of head and neck cancer patients

2017

Abstract The landscape of human papillomavirus (HPV) infection in racial/ethnic subgroups of head and neck cancer (HNC) patients has not been evaluated carefully. In this study, a meta-analysis examined the prevalence of HPV in HNC patients of African ancestry. Additionally, a pooled analysis of subject-level data was also performed to investigate HPV prevalence and patterns of p16 (CDNK2A) expression amongst different racial groups. Eighteen publications (N = 798 Black HNC patients) were examined in the meta-analysis, and the pooled analysis included 29 datasets comprised of 3129 HNC patients of diverse racial/ethnic background. The meta-analysis revealed that the prevalence of HPV16 was h…

OncologyOROPHARYNGEAL CANCERHPVCancer Researchmedicine.medical_specialtyEthnic groupUNITED-STATESOriginal Manuscript03 medical and health sciences0302 clinical medicineInternal medicinemedicineP16 IMMUNOHISTOCHEMISTRYHuman papillomavirus030223 otorhinolaryngologyEPSTEIN-BARR-VIRUSE6/E7 MESSENGER-RNAAFRICAN-AMERICANSHUMAN-PAPILLOMAVIRUS TYPE-16IMPROVED SURVIVALbusiness.industryPOTENTIALLY MALIGNANT DISORDERSHead and neck cancerHPV infectionCancerOrvostudományokGeneral Medicinemedicine.diseaseRacial ethnic3. Good healthPooled analysis030220 oncology & carcinogenesisSmoking statusSettore MED/31 - OTORINOLARINGOIATRIASQUAMOUS-CELL CARCINOMAEgészségtudományokbusiness
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I codici in scrittura latina di Alessandro Farnese (1520-1589) a Caprarola e al Palazzo della Cancelleria nel 1589

2016

This article analyses the contents of the manuscripts in Latin script found at the Villa Farnese of Caprarola and the Palazzo della Cancelleria of Rome at the death of Cardinal Alessandro Farnese (1520-1589). They were inventoried by Claudio Tobalducci, librarian to the Cardinal; the inventories were edited by Francois Fossier. Although the manuscript collections seem neither organic nor systematically constituted by the Cardinal (the volumes were mainly borrowed from the great Farnese library in the Palazzo Farnese in Rome), the manuscripts were used by the Cardinal in the last years of his life. They shed light on at least some of the personal interests of this important ecclesiastical, p…

Palazzo della CencelleriarenessanssiFarnese AlessandrokirjahistoriakardinaalitCaprarolavastauskonpuhdistusmanuscripts in Latin script
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rec. di: A. Persius Flaccus, ed. W. Kissel, Berolini et Novi Eboraci 2007

2011

Persius manuscripts emendations
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