Search results for "Minor"

showing 10 items of 877 documents

Immunosurveillance of lung melanoma metastasis in EBI-3-deficient mice mediated by CD8+ T cells.

2008

Abstract EBV-induced gene 3 (EBI-3) codes for a soluble type I receptor homologous to the p40 subunit of IL-12 that is expressed by APCs following activation. In this study, we assessed the role of EBI-3 in a model of lung melanoma metastasis. Intravenous injection of the B16-F10 cell line resulted in a significant reduction of lung tumor metastasis in EBI-3−/− recipient mice compared with wild-type mice. The immunological finding accompanying this effect was the expansion of a newly described cell subset called IFN-γ producing killer dendritic cells associated with CD8+ T cell responses in the lung of EBI-3−/− mice including IFN-γ release and TNF-α-induced programmed tumor cell death. Depl…

Cytotoxicity ImmunologicAdoptive cell transferLung NeoplasmsT cellImmunologyMelanoma ExperimentalBiologyCD8-Positive T-LymphocytesArticleMetastasisMinor Histocompatibility AntigensGene Knockout TechniquesMiceCell Line TumormedicineImmunology and AllergyCytotoxic T cellAnimalsLung MelanomaReceptors CytokineImmunologic SurveillanceCell Line TransformedMice KnockoutMelanomamedicine.diseaseImmunosurveillanceMice Inbred C57BLmedicine.anatomical_structureCell Transformation NeoplasticImmunologyInjections IntravenousAnimals; CD8-Positive T-Lymphocytes; Cell Line Transformed; Cell Line Tumor; Cell Transformation Neoplastic; Cytotoxicity Immunologic; Gene Knockout Techniques; Immunologic Surveillance; Injections Intravenous; Lung Neoplasms; Melanoma Experimental; Mice; Mice Inbred C57BL; Mice Knockout; Neoplasm Transplantation; Receptors Cytokine; T-Box Domain ProteinsCancer researchT-Box Domain ProteinsCD8Neoplasm Transplantation
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A continuous infusion of a minor histocompatibility antigen-immunodominant peptide induces a delay of male skin graft rejection.

2009

Abstract We previously reported that an inhibition of antigen-specific Interferon-γ release and cytotoxicity occurs after a continuous infusion of an HY immunodominant peptide although this treatment is not able to cause a significant delay of male skin grafts rejection. In vivo administration of high doses of an HY peptide, through mini-osmotic pumps, in naive female mice was used to study the effects on the male skin grafts rejection. A continuous infusion of 1 mg of an HY peptide induces a significant delay of male skin graft rejection. In vitro HY-specific Interferon-γ release was inhibited adding peptide-specific suppressor cells: the ability to inhibit Interferon-γ release was evident…

Cytotoxicity ImmunologicGraft RejectionMaleImmunologyAntigen presentationH-Y AntigenPharmacologyCD8-Positive T-LymphocytesT-Lymphocytes RegulatoryMinor Histocompatibility AntigensInterferon-gammaMiceImmune systemMinor Histocompatibility antigenInterferonMinor histocompatibility antigenmedicineImmunology and AllergyAnimalsSuppressor cellInfusion PumpsSettore MED/04 - Patologia GeneraleImmunosuppression TherapyAntigen PresentationRodentCD40biologyImmunodominant EpitopesT-cell receptorCD28Forkhead Transcription FactorsHematologyDendritic CellsSkin TransplantationPeptide FragmentsAntigen presentation; Minor Histocompatibility antigen; graft rejection; Suppressor cells; RodentMice Inbred C57BLImmunologybiology.proteinB7-1 AntigenFemaleE-SelectinCD8medicine.drugImmunobiology
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Can Cross-Border Healthcare Be Sustainable? An Example from the Czech-Austrian Borderland

2019

Cross-border public services are considered to be one of the possible tools to eliminate the periphery position of border regions. The Czech part of the Gm&uuml

Czechcross-border public servicesCzech-Austrian cross-border cooperationmedia_common.quotation_subjectGeography Planning and DevelopmentCzech-Austrian cross-border cooperation; healthcare; twin towns; cross-border public services; EU fundsContext (language use)Minor (academic)010501 environmental sciencesManagement Monitoring Policy and LawPublic administration01 natural sciencesPolitical scienceHealth care050602 political science & public administration0105 earth and related environmental sciencesmedia_commonEU fundsRenewable Energy Sustainability and the Environmentbusiness.industry05 social scienceshealthcareLegislaturelanguage.human_language0506 political scienceSurpriseGeneral partnershiplanguagePosition (finance)businesstwin townsSustainability
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I diritti e le età della vita

2013

DIRITTI DEI MINORISettore IUS/20 - Filosofia Del Diritto
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i diritti dei minori. educazione e formazione per la tutela dell'infanzia

2014

DIRITTI EDUCAZIONEMINORISettore M-PSI/05 - Psicologia Sociale
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Single molecule localization microscopy of the distribution of chromatin using Hoechst and DAPI fluorescent probes.

2014

Several approaches have been described to fluorescently label and image DNA and chromatin in situ on the single-molecule level. These superresolution microscopy techniques are based on detecting optically isolated, fluorescently tagged anti-histone antibodies, fluorescently labeled DNA precursor analogs, or fluorescent dyes bound to DNA. Presently they suffer from various drawbacks such as low labeling efficiency or interference with DNA structure. In this report, we demonstrate that DNA minor groove binding dyes, such as Hoechst 33258, Hoechst 33342, and DAPI, can be effectively employed in single molecule localization microscopy (SMLM) with high optical and structural resolution. Upon ill…

DNA ReplicationHoechstDNA RepairDNA repairBiologyfluorescence microscopyDAPIchemistry.chemical_compoundphotoconversionsuper-resolution microscopylocalization microscopyFluorescence microscopeSPDMAnimalsHumansDAPIdSTORMSMLMFluorescent DyesMicroscopySuper-resolution microscopynucleusDNA replicationdSTORCell BiologyDNADNA Minor Groove BindingChromatinChromatinCell biologychemistryMicroscopy FluorescencechromatinblinkingDNAResearch PaperNucleus (Austin, Tex.)
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"Table 103" of "Studies of QCD at e+ e- centre-of-mass energies between 91-GeV and 209-GeV."

2004

Thrust Minor distribution at c.m. energy 133.00 GeV.

DSIG/DMINORSingle Differential Cross Section133.0Astrophysics::High Energy Astrophysical PhenomenaE+ E- --> HADRONSE+ E- ScatteringPhysics::Space PhysicsExclusiveHigh Energy Physics::ExperimentNuclear Experiment
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"Table 107" of "Studies of QCD at e+ e- centre-of-mass energies between 91-GeV and 209-GeV."

2004

Thrust Minor distribution at c.m. energy 189.00 GeV.

DSIG/DMINORSingle Differential Cross Section189.0Astrophysics::High Energy Astrophysical PhenomenaE+ E- --> HADRONSE+ E- ScatteringPhysics::Space PhysicsExclusiveHigh Energy Physics::ExperimentNuclear Experiment
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"Table 109" of "Studies of QCD at e+ e- centre-of-mass energies between 91-GeV and 209-GeV."

2004

Thrust Minor distribution at c.m. energy 206.00 GeV.

DSIG/DMINORSingle Differential Cross Section206.0Astrophysics::High Energy Astrophysical PhenomenaE+ E- --> HADRONSE+ E- ScatteringPhysics::Space PhysicsExclusiveHigh Energy Physics::ExperimentNuclear Experiment
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"Table 102" of "Studies of QCD at e+ e- centre-of-mass energies between 91-GeV and 209-GeV."

2004

Thrust Minor distribution at c.m. energy 91.20 GeV.

DSIG/DMINORSingle Differential Cross SectionAstrophysics::High Energy Astrophysical PhenomenaE+ E- --> HADRONSE+ E- ScatteringPhysics::Space PhysicsExclusiveHigh Energy Physics::Experiment91.2Nuclear Experiment
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