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showing 10 items of 464 documents

INHIBITION OF CELLULAR GROWTH AND STEROID 11β-HYDROXYLATION INRAS-TRANSFORMED ADRENOCORTICAL CELLS BY THE FUNGAL TOXINS BETICOLINS

1996

Abstract The proliferation of GM16 and 4CDTras-transformed newborn rat adrenocortical (RTAC) cells and Y1 mouse adrenal tumor cells was inhibited by beticolins, the fungal toxins extracted fromCercospora beticola, at submicromolar concentrations in a dose-dependent manner. Inhibitory concentrations for half the maximum inhibition were 150, 75 and 25 n M for beticolin-1 and 230, 150 and 50 n M for beticolin-2 in GM16, 4CDT and Y1 cells respectively. Beticolins strongly inhibited the production of 11β-hydroxysteroids on the second and third days of treatment in a dose-dependent manner between 0.1 and 1 μ M . Beticolins were shown by confocal microscopy to be localized in cytoplasmic organelle…

medicine.medical_treatmentAdrenal Gland NeoplasmsBiologyTransfectionHeterocyclic Compounds 4 or More RingsSteroidlaw.inventionHydroxylationMiceStructure-Activity Relationshipchemistry.chemical_compoundConfocal microscopylawOrganelleTumor Cells CulturedmedicineAnimalsCells CulturedHydroxysteroidsMicroscopy ConfocalDose-Response Relationship DrugCell growthCell BiologyGeneral MedicineMycotoxinsGrowth InhibitorsNeoplasm ProteinsRatsCell Transformation NeoplasticGenes rasAnimals NewbornchemistryBiochemistryCytoplasmAdrenal CortexSteroid 11-beta-HydroxylaseSignal transductionGrowth inhibitionCell DivisionCell Biology International
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"Di generazione in generazione: 'mores', 'memoria', 'munera' nel 'de officiis' di Cicerone

2012

L’esigenza di ricordare, di comparare ieri e oggi si traduce nell’individuazione della distanza e della discontinuità tra passato e presente; ma non si esaurisce nella definizione di modelli di memoria contrappresentistici. Assumendo come dato di fatto il crollo irreversibile che ha travolto le istituzioni della vita pubblica e le trasformazioni dei comportamenti, il de officiis diventa infatti il luogo dell’elaborazione del cambiamento. Nella sua ultima opera Cicerone discute e manipola i capisaldi dell’identità comune, e riconfigura il rapporto tra azioni compiute per il proprio tornaconto e azioni compiute per il bene comune attraverso un intervento che trova il suo centro nella riflessi…

memoria mores officiumSettore L-FIL-LET/04 - Lingua E Letteratura Latina
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Espais modificats

2002

Aproximació al desenvolupament arquitectònic del campus de Blasco Ibáñez de la Universitat de València i, en especial, a les obres de Moreno Barberá.

moreno barberáUNESCO::HISTORIAuniversitat de valènciaarquitectura:HISTORIA [UNESCO]campus de blasco ibáñez
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Effect of saddle height on skin temperature measured in different days of cycling

2016

Infrared thermography can be useful to explore the effects of exercise on neuromuscular function. During cycling, it could be used to investigate the effects of saddle height on thermoregulation. The aim of this study was to examine whether different cycling postures, elicited by different knee flexion angles, could influence skin temperature. Furthermore, we also determined whether the reproducibility of thermal measurements in response to cycling differed in the body regions affected or not affected by saddle height. Sixteen cyclists participated in three tests of 45 min of cycling at their individual 50 % peak power output. Each test was performed in a different knee flexion position on …

musculoskeletal diseasesmedicine.medical_specialtyMaterials scienceThermal imagingMedicina esportiva03 medical and health sciences0302 clinical medicinemedicineExerciseSaddleReproducibilityMultidisciplinaryResearchBike-fit030229 sport sciencesRepeatabilityThermoregulationmusculoskeletal systemReliabilityTrunkReproducibilitySurgeryThermographyInfrared thermographyBody regionFisiologia humanaCycling030217 neurology & neurosurgeryBiomedical engineeringSpringerPlus
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PREPARAZIONE E CARATTERIZZAZIONE DI NANOSISTEMI LIPIDICI PER IL DIREZIONAMENTO E IL RILASCIO MODIFICATO DI FARMACI E ACIDI NUCLEICI IN TERAPIA ONCOLO…

2016

sono stati sviluppati sistemi nanoparticellari in grado di intrappolare elevate quantità di farmaci e di legare materiale genico. I sistemi preparati sono stati caratterizzati da un punto di vista chimico-fisico e tecnologico farmaceutico. Sono stati infine utilizzati per prove in vitro e i risultati ottenuti hanno mostrato che essi possiedono le caratteristiche per potere essere considerati dei validi carrier per farmaci e materiale genico nel trattamento oncologico.

nanoparticelleterapia genicatumorecarcinoma ovariconanoparticelle; cancro; terapia genica; antitumorali; drug delivery; epatocarcinoma; carcinoma ovaricocaratterizzazioneSettore CHIM/09 - Farmaceutico Tecnologico Applicativodrug and gene deliverydrug deliverycancroantitumoraliepatocarcinoma
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Las necesidades educativas especiales de los niños con tumores intracraneales

2000

Los tumores del sistema nervioso central (S.N.C.) son el segundo tipo de neoplasias más usuales en la infancia, después de las leucemias, y constituyen uno de los retos más importantes, tanto para los médicos, como para los psicólogos, pedagogos y maestros, en su tarea de mejorar o compensar las secuelas neurológicas derivadas de la enfermedad y de los tratamientos. En la práctica las secuelas son el precio que un niño con tumor intracraneal debe pagar por vivir, y la meta futura es intentar evitarlas, prevenirlas y tratarlas. Las posibilidades de recuperación del niño con un tumor intracraneal son muchas e importantes. La rehabilitación neuropsicológica debe comenzar lo antes posible: cuan…

necesidades educativas especialescáncer infantilrehabilitación neuropsicológicatumores intracraneales
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Fatti e Fabule. Geografie more-than-wet del Mediterraneo Nero

2023

oceanic turntelling turnturbulent materialitymore-than-wetSettore M-GGR/01 - GeografiaBlack Mediterranean
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Odontoma intraóseo erupcionado: Una infrecuente patología

2005

Objetivos: Los odontomas que afectan a los tejidos blandos son muy infrecuentes, pudiendo presentarse bajo dos formas clinicas: odontoma periférico y odontoma erupcionado. Se documenta un caso de odontoma erupcionado con el objetivo de discutir entre ambas formas de presentación clínica de esta patología. Diseño del estudio: Estudio de caso. Resultados: Se presenta el caso de un varón con una masa dura localizada en la región posterior del reborde alveolar izquierdo del maxilar superior, de un año de evolución y lento crecimiento. La ortopantomografía mostró la presencia de una tumoración radiodensa en la región posterior del maxilar izquierdo. El estudio histológico de la pieza operatoria …

odontoma periféricoUNESCO::CIENCIAS MÉDICASOdontología:CIENCIAS MÉDICAS [UNESCO]odontoma erupcionadoCiencias de la saludodontomaTumores odontogénicos
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Intervención psicoeducativa en el alumnado con cáncer. Trayectoria profesional e investigadora en esta materia de la profesora Claudia Grau Rubio

2014

Se describe la trayectoria profesional e investigadora de la profesora Claudia Grau Rubio desde el año 1983,con respecto a la temática "intervención psicoeducativa en el alumnado con cáncer".

oncología pediátrica cáncer infantil. tumores pediátricos SNC familia educación
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Las formas cotidianas de la felicidad y sus mandatos: Pedagogías del pensamiento positivo, trabajo docente y subjetividad en el neoliberalismo contem…

2020

Positive thinking constitutes one of the great traditions that lead to the idea of the subject as an entrepreneur of himself and is perhaps one of the best that has successfully condensed cultural, political, social and pedagogical processes linked to reflection on well-being in this historical time. The teaching work is especially moved by the pregnancy of these perspectives that challenge the pedagogical field and the education workers as ?agents of change, or at least one more school available to give the discussion on well-being and happiness (yours and the students?) is celebrated and encouraged. In this article, I intend to understand what is being built as pedagogical discourses abou…

or at least one more school available to give the discussion on well-being and happiness (yours and the students?) is celebrated and encouraged. In this articletrabajo docente y subjetividad en el neoliberalismo contemporáneo CarideI intend to understand what is being built as pedagogical discourses about teaching work from the different contemporary expressions of positive thinkingpedagogies. 119 129are received and recreated daily in schools and the wider pedagogical field Trabajo DocenteLucía Positive thinking constitutes one of the great traditions that lead to the idea of the subject as an entrepreneur of himself and is perhaps one of the best that has successfully condensed culturalsocial and pedagogical processes linked to reflection on well-being in this historical time. The teaching work is especially moved by the pregnancy of these perspectives that challenge the pedagogical field and the education workers as ?agents of changeas well as the ways in which these discourses circulatePedagogías del pensamiento positivo [1137-7038 8537 Arxius de sociologia 562372 2020 42 7674036 Las formas cotidianas de la felicidad y sus mandatos]Pedagogías.:SOCIOLOGÍA [UNESCO]Pensamiento PositivoCoachingteaching work1137-7038 8537 Arxius de sociologia 562372 2020 42 7674036 Las formas cotidianas de la felicidad y sus mandatos: Pedagogías del pensamiento positivoUNESCO::SOCIOLOGÍApoliticalpositive thinking
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