Search results for "POD"

showing 10 items of 1958 documents

Inducible ASABF-Type Antimicrobial Peptide from the Sponge Suberites domuncula: Microbicidal and Hemolytic Activity in Vitro and Toxic Effect on Moll…

2011

Since sponges, as typical filter-feeders, are exposed to a high load of attacking prokaryotic and eukaryotic organisms, they are armed with a wide arsenal of antimicrobial/cytostatic low-molecular-weight, non-proteinaceous bioactive compounds. Here we present the first sponge agent belonging to the group of ASABF-type antimicrobial peptides. The ASABF gene was identified and cloned from the demospongeSuberites domuncula. The mature peptide, with a length of 64 aa residues has a predicted pI of 9.24, and comprises the characteristic CSαβ structural motif. Consequently, the S. domuncula ASABF shares high similarity with the nematode ASABFs ; it is distantly related to the defensins. The recom…

ASABFAntimicrobial peptidesGastropodaMolecular Sequence DataPharmaceutical SciencePeptideMicrobial Sensitivity TestsGram-Positive BacteriaReal-Time Polymerase Chain ReactionArticleMicrobiology03 medical and health sciencesantimicrobial peptidesAnti-Infective AgentsSequence Analysis ProteinDrug DiscoveryAnimalsBittium sp.Structural motiflcsh:QH301-705.5Pharmacology Toxicology and Pharmaceutics (miscellaneous)spongesPhylogeny030304 developmental biologychemistry.chemical_classification0303 health sciencesbiology030306 microbiologyEffectorHemolytic AgentsapoptosisGeologyBittium spsponges; <em>Suberites domuncula</em>; ASABF; antimicrobial peptides; apoptosis; <em>Bittium</em> sp.biology.organism_classificationSuberites domunculasponges ; Suberites domuncula ; ASABF ; antimicrobial peptides ; apoptosis ; Bittium sp.Recombinant ProteinsSuberites domunculaSpongeEnzymelcsh:Biology (General)chemistryMolluscaSuberitesSuberitesAntimicrobial Cationic PeptidesMarine Drugs
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A broader model for C 4 photosynthesis evolution in plants inferred from the goosefoot family (Chenopodiaceae s.s.)

2012

C 4 photosynthesis is a fascinating example of parallel evolution of a complex trait involving multiple genetic, biochemical and anatomical changes. It is seen as an adaptation to deleteriously high levels of photorespiration. The current scenario for C 4 evolution inferred from grasses is that it originated subsequent to the Oligocene decline in CO 2 levels, is promoted in open habitats, acts as a pre-adaptation to drought resistance, and, once gained, is not subsequently lost. We test the generality of these hypotheses using a dated phylogeny of Amaranthaceae s.l. (including Chenopodiaceae), which includes the largest number of C 4 lineages in eudicots. The oldest chenopod C 4 lineage da…

AcclimatizationLineage (evolution)Drought toleranceChenopodiaceaePoaceaeGeneral Biochemistry Genetics and Molecular BiologyCarbon CycleSpecies SpecificityBotanyPoaceaePhotosynthesisMolecular clockChenopodiaceaeEudicotsResearch ArticlesPhylogenyGeneral Environmental ScienceAmaranthaceaeGeneral Immunology and MicrobiologybiologyEcologyfood and beveragesGeneral MedicineCarbon Dioxidebiology.organism_classificationBiological EvolutionCarbonDroughtsSaltsAdaptationParallel evolutionGeneral Agricultural and Biological SciencesProceedings of the Royal Society B: Biological Sciences
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Ferro-pedrizite, NaLi2(Fe2+ 2Al2Li)Si8O22(OH)2, a new amphibole-supergroup mineral from the Sutlug pegmatite, Tyva Republic, Russia

2015

Ferro-pedrizite, a new amphibole-supergroup mineral was discovered in the Sutlug pegmatite occurrence situated in the Targi River Basin, Tyva Republic, Eastern Sibera, Russia. The associated minerals are quartz, albite, microcline, spodumene, cassiterite, beryl, columbite-(Mn), fergusonite-β-(Y), fluorapatite, schorl, trilithionite and fluorite. Ferro-pedrizite forms dark grey-blue to violet-blue acicular and long prismatic crystals up to 2 × 5 × 50 mm and their aggregates. D meas = 3.16(1) g/cm3 (by hydrostatic weighing), 3.13(1) g/cm3 (by flotation in heavy liquids); D calc = 3.135 g/cm3. Ferro-pedrizite is optically biaxial (−), α = 1.614(3), β = 1.638(3), γ = 1.653(3), 2 V meas = 75(5)°…

AcicularMicroclineChemistryCassiteriteAnalytical chemistryMineralogyминералыТуваengineering.materialпегматитыSpodumeneAlbiteGeochemistry and PetrologyengineeringChemical compositionAmphibolePegmatiteEuropean Journal of Mineralogy
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1992 o del equívoco europeo

1989

Acta ÚnicaSociedadPoderVidal-Beneyto JoséOCDEPolíticaCivilizaciónOTANEUROPAEstadoEconomíaPublicaciones: Obra periodística: Columnas y artículos de opiniónThatcherProgresoDesregulaciónCEE
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Prostitución y tratas de blancas

2003

Actividad sexualManifestaciones de prostitutasEstructura mafiosaLegislaciones europeasVidal-Beneyto JoséPrisiónPoderes públicosOpción reglamentistaOpción prohibicionistaProstituciónServicios sexualesEUROPAPublicaciones: Obra periodística: Columnas y artículos de opiniónMafiasClientesProxenetasLibertad sexualUnión EuropeaFrancia SarkozySociedad patriarcalDrogasTrata de blancasOpción abolicionista
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The compensatory regeneration of the operculum ofHydroides norvegica: Identification of the inhibiting substance

1973

In the polychete Hydroides norvegica there are two opercula with different degrees of organization: one is completely developed and functional, the other, present only in rudimentary outline. The latter only begins to develop when the functional operculum is removed. It was observed that in the whole body of the Hydroides, but particularly in the functional operculum, there is a substance which inhibits the development of the rudimental operculum. This substance was purified in order to determine its chemical nature. From preparation of opercular homogenates we chemically separated numerous fractions, each of which was tested for inhibitory activity and chemical and physical properties. The…

Adenosine monophosphateCompensatory regenerationHeat resistantbiologyGeneral MedicineAnatomybiology.organism_classificationHydroides norvegicachemistry.chemical_compoundchemistryBiochemistryvisual_artHydroidesvisual_art.visual_art_mediumAnimal Science and ZoologyWhole bodyOperculum (gastropod)Journal of Experimental Zoology
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The influence of food competition and host specificity on the transmission of Triaenophorus crassus (Cestoda) and Cystidicola farionis (Nematoda) to …

2000

Abstract As a superior competitor for planktonic food, vendace ( Coregonus albula ), when abundant, is expected to displace whitefish ( Coregonus lavaretus ) from feeding on plankton and to force it to rely more on benthic food. The predicted result would be a reduced abundance of the copepod-transmitted cestode Triaenophorus crassus in whitefish, but an increase in the abundance of the nematode Cystidicola farionis transmitted via benthic amphipods. We studied the occurrence of both parasites in whitefish during 1991–1996 in three interconnected areas at Lake Saimaa, Finland, where the densities of the vendace stocks varied due to natural fluctuation in year-class strengths. In accordance …

AdolescentNematodaPopulationSpirurida InfectionsBiologyPopulation densityZooplanktonHost-Parasite InteractionsFish DiseasesfoodCoregonus lavaretusCrustaceaCoregonus albulaAnimalsHumansCoregonuseducationSalmonidaeFinlandeducation.field_of_studyfood.dishEcologyfungiFeeding Behaviorbiology.organism_classificationCestode InfectionsInfectious DiseasesCestodaParasitologyCopepodSalmonidaeSpiruroideaInternational journal for parasitology
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Soccer players' fitting perception of different upper boot materials.

2016

[EN] The present study assessed the influence of upper boot materials on fitting perception. Twenty players tested three soccer boots only differing in the upper boot material (natural calf leather, natural kangaroo leather and synthetic leather). Players reported fitting perception and preference on specific foot areas using a perceived fitting scale. Ratings were averaged for every foot area. Repeated measures ANOVA was used to analyze the differences between boots. The kangaroo leather boots were perceived tighter and closer to the preferred fitting in general fitting, metatarsals area and instep area. The synthetic leather boots were perceived as the loosest and as the most distant boot…

AdultEngineeringmedia_common.quotation_subjectFootballPhysical Therapy Sports Therapy and RehabilitationHuman Factors and ErgonomicsUpperFootwear03 medical and health sciencesYoung Adult0302 clinical medicinePerceptionStatisticsSoccerAnimalsHumans0501 psychology and cognitive sciencesOperations managementSafety Risk Reliability and QualityEngineering (miscellaneous)050107 human factorsmedia_commonMacropodidaeAnalysis of Variancebusiness.industry05 social sciences030229 sport sciencesEquipment DesignConsumer BehaviorComfortShoesLeatherLeather bootsCattlePerceptionFittingbusinessApplied ergonomics
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Kosaki overgrowth syndrome: A novel pathogenic variant in PDGFRB and expansion of the phenotype including cerebrovascular complications

2020

Heterozygous activating variants in platelet-derived growth factor, beta (PDGFRB) are associated with phenotypes including Kosaki overgrowth syndrome (KOGS), Penttinen syndrome and infantile myofibromatosis (IM). Here, we present three new cases of KOGS, including a patient with a novel de novo variant c.1477A > T p.(Ser493Cys), and the oldest known individual age 53 years. The KOGS phenotype includes characteristic facial features, tall stature, scoliosis, hyperelastic thin skin, lipodystrophy, variable intellectual and neurological deterioration, and abnormalities on brain imaging. Long-term outcome is unknown. Our cases confirm the phenotypic spectrum includes progressive flexion contrac…

AdultMale0301 basic medicinePathologymedicine.medical_specialtyInfantile myofibromatosisPDGFRBScoliosis030105 genetics & heredityCraniosynostosisReceptor Platelet-Derived Growth Factor beta03 medical and health sciencesCamptodactylyGeneticsmedicineHumansJoint dislocationStrokeGrowth DisordersGenetics (clinical)business.industryGenetic VariationMiddle Agedmedicine.diseaseCerebrovascular DisordersPhenotype030104 developmental biologymedicine.symptomLipodystrophybusinessClinical Genetics
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Age-Related Lipid Metabolic Signature in HumanLMNA-Lipodystrophic Stem Cell-Derived Adipocytes

2015

Lamin A (LMNA)-linked lipodystrophies belong to a group of clinical disorders characterized by a redistribution of adipose tissue with a variable range of metabolic complications. The leading cause of these disorders is the nonphysiological accumulation of the lamin A precursor, prelamin A. However, the molecular mechanisms by which prelamin A induces the pathology remain unclear.The aim of this study is to use an experimental LMNA-lipodystrophy model based on human mesenchymal stem cell (hMSC)-derived adipocytes that accumulate prelamin A to gain deeper insights into the mechanisms governing these diseases.Prelamin A-induced or -noninduced hMSC-derived adipocytes were obtained from healthy…

AdultMaleAgingcongenital hereditary and neonatal diseases and abnormalitiesmedicine.medical_specialtyAdolescentLipodystrophyLipolysisEndocrinology Diabetes and MetabolismCellular differentiationClinical BiochemistryAdipose tissueMitochondrionBiologyBiochemistryLMNAYoung AdultEndocrinologyInternal medicineAdipocytesmedicineHumansMetabolomicsLipolysisintegumentary systemStem CellsBiochemistry (medical)Mesenchymal stem cellnutritional and metabolic diseasesCell DifferentiationMiddle AgedLamin Type ALipid MetabolismEndocrinologyMetabolomeFemaleStem cellLaminThe Journal of Clinical Endocrinology &amp; Metabolism
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