Search results for "PSO"

showing 10 items of 679 documents

1985. IV congreso del PSPV-PSOE. Alicante, abril de 1985. "Seguim treballant pel canvi"

2014

El periodo entre el III congreso de Benicàssim (1982) y el IV congreso de Alicante (abril 1985) del PSPV son claves en la configuración de la estructura del poder orgánico e institucional de los socialistas valencianos, y van a marcar la década siguiente, hasta que cambie el ciclo político y gobierne el Partido Popular en 1995. Previo al IV congreso del PSPV-PSOE se celebrará el XXX Congreso Federal del PSOE. Madrid. Los socialistas valencianos asistirán al XXX Congreso Federal del PSOE con 112 delegados que representaban a más de 24.000 militante. El PSPV-PSOE era la segunda federación del PSOE, tras la andaluza. El cabeza de delegación del PSPV-PSOE al XXX congreso, Antonio García Miralle…

:CIENCIA POLÍTICA [UNESCO]UNESCO::HISTORIAUNESCO::CIENCIA POLÍTICAConsell Preautonómico del País ValenciàUNESCO::SOCIOLOGÍACongreso Federal del PSOEIV congreso nacional del PSPV-PSOE:HISTORIA [UNESCO]:SOCIOLOGÍA [UNESCO]
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Nuevas estrategias farmacológicas en el tratamiento de la psoriasis = New pharmacological strategies for the treatment of psoriasis

2013

La psoriasis es una enfermedad inflamatoria crónica caracterizada por la inflamación de la piel, que viene acompañada por hiperproliferación de los queratinocitos, infiltración leucocitaria dérmica y una angiogénesis incrementada. Los mecanismos patológicos que dirigen esta patología incluyen tanto respuestas de la inmunidad innata como de la adaptativa. En la presente tesis doctoral se ha ahondado en el estudio de la respuesta fisiopatológica de los queratinocitos a los cambios que se producen en el entorno de una placa psoriásica, con el objetivo de aportar evidencia de relevancia para el desarrollo de nuevos tratamientos farmacológicos. De este modo, se ha puesto de manifiesto que los me…

:CIENCIAS MÉDICAS ::Farmacología [UNESCO]psoriasisUNESCO::CIENCIAS MÉDICAS ::Farmacologíafarmacología
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A dual channel sulphur-containing a macrocycle functionalised BODIPY probe for the detection of Hg(II) in a mixed aqueous solution

2018

We report herein the synthesis and chromo-fluorogenic behaviour of a new probe 1 containing a boron-dipirromethene (BODIPY) unit electronically connected with a dithia-dioxa-aza macrocycle. Acetonitrile and water-acetonitrile 95:5 v/v solutions of the probe showed an ICT band in the visible zone and are nearly non-emissive. When acetonitrile was used as solvent, addition of Hg(II) and trivalent metal cations induced an hypsochromic shift of the absorption band and moderate emission enhancements. A highly selective response was obtained when using competitive media such as wateracetonitrile 95:5 v/v. In this case only Hg(II) induced a hypsochromic shift of the absorption band and a marked em…

:Ciências Químicas [Ciências Naturais]BodipyHeterocyclesColorimetric sensor010402 general chemistryPhotochemistry01 natural sciencesCatalysisMetalchemistry.chemical_compoundSynthesisQUIMICA ORGANICABODIPYMaterials ChemistryFluorimetric sensorDetection in aqueous solutionAcetonitrileDual channel chemosensorCrown etherchemistry.chemical_classificationAqueous solutionScience & Technology010405 organic chemistryChemistryOptical chemosensorQUIMICA INORGANICAWaterGeneral ChemistryMercuryCiências Naturais::Ciências QuímicasFluorescence3. Good health0104 chemical sciencesAbsorption bandvisual_artHg (II)Coordinationvisual_art.visual_art_mediumHypsochromic shiftfluorescenceBODIPYCrown ether
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Latvijas Universitātes Raksti. 755. sēj.

2010

:MEDICINE [Research Subject Categories]Iron deficiencyDzelzs deficīts2. tipa cukura diabētsVairogdziedzera vēzisUzmanības deficīta sindromsAerobās darbspējasEndoskopiska retrogrāda holangiopankreatogrāfijaMedicīniskās palīdzības pieejamībaPsoriāzeSkin precursor cellsBody massCitokīniType 2 diabetes mellitusKoagulāzes negatīvie stafilokoki
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Plant diseases a herald of environmental changes

2011

Environmental changes can alter morphology and physiology of plants, and geographic distribution of both wild and cultural species. All these modifications reflect in plant-associated microflora and development of plant pathogens as well. Climate warming causes a pole-ward shift not only different plants but also their pathogens. Poster in 4th International Conference of Botanic Gardens from the Baltic Sea Region "Botanic gardens network for the development of the Baltic Sea Region", 29 September - 2 October, 2011, Gdansk, Poland

:NATURAL SCIENCES::Biology [Research Subject Categories]powdery mildrewfungifood and beveragesErysiphalesGalanthus plicatusMelampsora allii-fragilis f. sp. galanthi-fragilisplant diseasesrhododendrongeographic locationsaugu slimības
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Binding mode analysis of ABCA7 for the prediction of novel Alzheimer's disease therapeutics

2021

Graphical abstract

ATP Adenosine-triphosphateNBD nucleotide binding domainGSH reduced glutathionePolypharmacologyAlzheimer’s disease (AD)ATP-binding cassette transporterHTS high-throughput screeningBiochemistryABCA7Structural BiologyPLIF protein ligand interactionMSD membrane spanning domainPDB protein data bankTM transmembrane helixABC ATP-binding cassetteMultitarget modulation (PANABC)RMSD root mean square distanceABC transporter (ABCA1 ABCA4 ABCA7)Computer Science ApplicationsMOE Molecular Operating EnvironmentPharmacophoreSNP single-nucleotide polymorphismBiotechnologyResearch ArticleBBB blood-brain barrierBiophysicsDrug designComputational biologyBiologyAD Alzheimer’s diseasePET positron emission tomographyIC intracellular helixAPP amyloid precursor proteincryo-EM cryogenic-electron microscopyGeneticsHomology modelingBinding siteRational drug design and developmentComputingMethodologies_COMPUTERGRAPHICSNBD-cholesterol 7-nitro-2-13-benzoxadiazol-4-yl-cholesterolTransporterPSO particle swarm optimizationPET tracer (PETABC)ECD extracellular domainR-domain/region regulatory domain/regionABCA1biology.proteinEH extracellular helixTP248.13-248.65BODIPY-cholesterol 44-difluoro-4-bora-3a4a-diaza-s-indacene-cholesterolComputational and Structural Biotechnology Journal
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Polypyrrole films functionalized with pendant titanocene dichloride complexes: Ellipsometric study of the electropolymerization process

2007

Electrochemical and ellipsometric methods have been used to study the electropolymerization process of a functionalized monomer, Tc3Py (in which pyrrole is covalently bonded with titanocene dichloride complex) on platinum electrode from a dilute monomer solution in acetonitrile. The deposition has been performed in the potentiodynamic regime. A new method for the acquisition and treatment of ellipsometric data has been proposed which allowed us to analyze the evolution of the film properties at each potential. The model of a single uniform layer was unable to describe the ellipsometric experimental observations with the necessary precision. A proper fitting of the data has been achieved con…

Absorbancechemistry.chemical_compoundMonomerchemistryAbsorption spectroscopyEllipsometryGeneral Chemical EngineeringElectrodeElectrochemistryAnalytical chemistryMolar absorptivityPolypyrroleElectrode potentialElectrochimica Acta
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1H NMR methodologies applied in the thermodynamic and structural characterization of organic supramolecular complexes

2021

Orientador: Anita Jocelyne Marsaioli Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Química Resumo: Nesta tese consiste no estudo de interações supramoleculares utilizando diferentes metodologias de Ressonância Magnética Nuclear de hidrogênio (RMN de 1H), tais como ROESY 1D, RMN-DOSY e RMN-STD. Os sistemas supramoleculares foram abordados em dois casos de estudo diferentes. O Capítulo I tem como objeto de estudo interações do fármaco Dapsona com diferentes carreadores de fármacos (ß-CD, SBE-ß-CD e lipossoma de EPC), com a finalidade de encontrar formulações nas quais a Dapsona seja mais solúvel. Os complexos binários e ternário formados foram determinadas por medidas de …

AcetilcolinesteraseCarreadores de fármacosAcetylcholinesterase1H NMRDapsonaEnzyme inhibitorsRMN de 1HDrug carriersInibidores enzimaticosDapsone
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Chromo-Fluorogenic Detection of Nerve-Agent Mimics Using Triggered Cyclization Reactions in Push-Pull Dyes

2010

A family of azo and stilbene derivatives (1-9) are synthesized, and their chromo-fluorogenic behavior in the presence of nerve-agent simulants, diethylchlorophosphate (DCP), diisopropylfluorophosphate (DFP), and diethylcyanophosphate (DCNP) in acetonitrile and mixed solution of water/acetonitrile (3:1 v/v) buffered at pH 5.6 with MES, is investigated. The prepared compounds contain 2-(2-N,N-dimethylaminophenyl)ethanol or 2-[(2-N,N-dimethylamino)phenoxy]ethanol reactive groups, which are part of the conjugated pi-system of the dyes and are able to give acylation reactions with phosphonate substrates followed by a rapid intramolecular N-alkylation. The nerve-agent mimic-triggered cyclization …

AcetonitrilesIsoflurophateSilica gelOrganic ChemistryWaterGeneral ChemistryConjugated systemPhotochemistryBiochemistryPhosphonateKineticschemistry.chemical_compoundOrganophosphorus CompoundsReaction rate constantchemistryCyclizationReagentSpectrophotometry UltravioletHypsochromic shiftReactivity (chemistry)Chemical Warfare AgentsGasesAcetonitrileFluorescent DyesNuclear chemistryChemistry - An Asian Journal
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A 588-gene microarray analysis of the peripheral blood mononuclear cells of spondyloarthropathy patients

2002

OBJECTIVES: To identify genes which are more highly expressed in the peripheral blood mononuclear cells (PBMC) of patients with spondyloarthropathy (SpA), rheumatoid arthritis (RA) and psoriatic arthritis (PsA), in comparison to normal subjects. METHODS: A 588-gene microarray was used as a screening tool to select a panel of such genes from PBMC of these subjects and of normal subjects. Results were then validated by reverse transcription-polymerase chain reaction (RT-PCR). RESULTS: The following genes were more highly expressed in arthritis patients than in normal subjects: macrophage differentiation marker MNDA (myeloid nuclear differentiation antigen), MRP8 and MRP14 (migratory inhibitor…

AdultGenetic MarkersMaleCCR1Receptors CXCR4AdolescentSpondyloarthropathyArthritisPeripheral blood mononuclear cellArthritis RheumatoidPsoriatic arthritisRheumatologymedicineHumansSpondylitis AnkylosingPharmacology (medical)AgedOligonucleotide Array Sequence AnalysisReverse Transcriptase Polymerase Chain Reactionbusiness.industryJanus kinase 3Arthritis PsoriaticSynovial MembraneMNDAInterleukinDNAMiddle Agedmedicine.diseaseAntigens DifferentiationChemokine CXCL12ImmunologyLeukocytes MononuclearFemalebusinessChemokines CXCRheumatology (Oxford, England)
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