Search results for "PV"
showing 10 items of 704 documents
Sperm DNA integrity and human papillomavirus (HPV) infections: a controversy that could be resolved by a new molecular approach
2020
Study question: The aim was to determine if HPVs affect spermatozoa DNA integrity. To resolve the discrepancy regarding the association between HPV infections and sperm DNA damage. Summary answer: To elucidate if HPV impairs DNA integrity, we suggest to investigate HPV DNA positivity in spermatozoa by a differential lysis procedure before TUNEL assay.
Effetti dell'infezione da HPV sugli esiti della fecondazione in vitro in pazienti sterili: dati preliminari di uno studio prospettico
2008
Microbiota e HPV nel carcinoma orale
2021
La carcinogenesi è un processo multifattoriale in cui sono coinvolti differenti fattori esogeni; tra questi, il microbiota sembra svolgere un ruolo attivo nei mec- canismi di sviluppo del carcinoma orale [1]. Nella presente trattazione saranno descritti i principali aspetti epidemiologici, clinici e patogenetici che vedono coinvolto il microbiota orale nel processo di carcinogenesi omodistrettuale. A tal proposito, per facilità di trattazione, è stata condotta una distinzione del microbiota orale in due gruppi: microbiota orale batterico e microbiota orale non batterico (i.e. Candida spp, Human Papilloma Virus). Fra i microrganismi appartenenti a quest’ultimo gruppo, verrà condotta una disa…
The role of the innate immune response in HPV-related oral and oropharyngeal cancer
2014
Introduction. During the last 20 years, the incidence of HPV-associated oropharyngeal cancer is increased. Principal actors of the innate immune response against HPV are represented by the TLRs (Toll like receptors). On the other hand different studies have reported that HPV can directly inhibit the functions of the TLRs pathway through interferons (IFNs). There are very few preliminary studies on the role of TLRs mediated HPV clearance in human oncology. Our study aim has been to evaluate whether TLR4 identifies HR-HPV integration state in OSCC. Methods. Protein levels of TLR4 in OSCC were assessed using Immunohistochemistry (IHC). In situ hybridization (ISH) for HPV-DNA detection in morph…
EPIDEMIOLOGIA DELLE LESIONI PRE-NEOPLASTICHE E NEOPLASTICHE DELLA CERVICE UTERINA
2006
Detección inmunohistoquímica de la proteína L1 de Virus Papiloma Humano (HPV) de alto riesgo en citologías y biopsias de cuello uterino
2005
Para confirmar la detección inmunohistoquímica de la proteína L1 de HPV de alto riesgo, tanto en citologías con anormalidades en células epiteliales como en biopsias con diagnóstico de carcinoma epidermoide cervical, se seleccionaron aleatoriamente: 11 citologías cervicales del año 2004 con interpretación citológica de anormalidades en células escamosas incluyendo: células escamosas atípicas y lesión intraepitelial escamosa de bajo y alto grado y 50 biopsias de cérvix con carcinoma epidermoide diagnosticados entre los años 1950 y 1980. Todas las muestras, tanto citológicas como histológicas fueron sometidas al procedimiento inmunohistoquímico para la detección de la proteína L1 de HPV de al…
Cilvēka papilomas vīrusa noteikšanas nozīme dzemdes kakla vēža skrīningā
2019
Latvijā vecumā no 15 – 44 gadiem dzemdes kakla vēzis ir visbiežāk sastopamais audzējs un otrais biežākais nāves cēlonis pēc krūts audzēja. Starp Ziemeļeiropas valstīm Latvijā ir visaugstākā dzemdes kakla vēža saslimstība un otrie augstākie mirstības rādītāji pēc Lietuvas. Cilvēka papilomas vīruss ir galvenais dzemdes kakla vēža ierosinātājs un pētījumi ir pierādījuši, ka ieviešot augsta riska HPV testu dzemdes kakla vēža skrīningā, audzēja saslimšanas un mirstības rādītāji ir samazinājušies HPV augstās sensitivitātes un negatīvi paredzamās vērtības dēļ. Darba mērķis ir novērtēt dzemdes kakla pirmsvēža stāvokļu sastopamību vienā Latvijas laboratorijā un to saistību ar HPV infekcijas sastopam…
Detection of Human Papillomavirus DNA in cervical samples: analysis of the new PGMY-PCR compared to Hybrid Capture II, MY-PCR and a Two-step nested P…
2004
The PGMY-PCR for human papillomavirus (HPV) was evaluated, in parallel with nested PCR (nPCR), in samples with noted Hybrid Capture II (HCII) and MY-PCR results. PGMY-PCR detected HPV DNA in 2.5% of HCII-negative-MY-PCR-negative samples and in 71.7% of HCII-positive-MY-PCR-negative samples; also, it detected the MY-PCR-negative-nPCR-negative types HPV-42, HPV-44, HPV-51, HPV-87, and HPV-89.
The presence of genital HPV does not affect the in vitro fertilization outcome: preliminary data of a prospective study
2009
LA PREVENZIONE ED IL TRATTAMENTO DELLE PATOLOGIE HPV-CORRELATE: FOLLOW-UP E PERFORMANCE RIPRODUTTIVA
2007
Relationship between HPV-infection and reproductive performance includes patients who during trial become pregnant. Main chapter indeed represents genital lesions treatments sequelae. Clinical phase 3 studies showed that spontaneous abortion rate in both groups (Gardasil and placebo respectively) was comparable (33% vs 31.6%). Moreover, there were 25 cases of congenital abnormalities among newborns and live foetuses, and congenital abnormalities global rate was similar than normal population. Therefore, there is no evidence that Gardasil adversely influences fertility, pregnancy and neonatal outcome. Cold-cut conization, laser-conization, laser-ablation, LEEP or LLETZ are conservative techn…