Search results for "Physiological psychology"

Brain Cortical Complexity and Subcortical Morphometrics in Lifelong Premature Ejaculation

2020

Premature ejaculation (PE) is the most common male sexual dysfunction. The brain disturbances that cause this disorder remain poorly understood. This study aimed to investigate how the morphology of cortical and subcortical brain structures differed in PE, how these morphologic differences were associated with severity measures of PE, such as intravaginal ejaculatory latency time (IELT), and how these cortical and subcortical structures were causally connected through mediation analysis. Anatomical MRI scans were acquired from 39 male participants, 23 with PE (28.78 ± 4.32 years), and 16 without PE (27.88 ± 3.65 years). We used a subcortical analysis package within FSL to perform subcortica…

The what, when, where, and how of visual word recognition

2014

A long-standing debate in reading research is whether printed words are perceived in a feedforward manner on the basis of orthographic information, with other representations such as semantics and phonology activated subsequently, or whether the system is fully interactive and feedback from these representations shapes early visual word recognition. We review recent evidence from behavioral, functional magnetic resonance imaging, electroencephalography, magnetoencephalography, and biologically plausible connectionist modeling approaches, focusing on how each approach provides insight into the temporal flow of information in the lexical system. We conclude that, consistent with interactive a…

Spatial learning and expression patterns of PP1 mRNA in mouse hippocampus.

2009

<i>Background:</i> Synaptic plasticity is believed to be the major cellular basis for learning and memory. Protein phosphorylation is a key process involved in changes in the efficacy of neurotransmission. In long-term changes synaptic plasticity is followed by structural plasticity and protein de novo synthesis. Such mechanisms are believed to build the basis of hippocampal learning and memory investigated in the Morris water maze (MWM) task. To examine the role of dephosphorylation during that model for spatial learning, we analyzed protein phosphatase 1 (PP1) expression in the hippocampus of mice at various stages of the task and in two groups with different learning abilitie…

2019

Today, several pharmaceutic and non-pharmaceutic approaches exist to treat psychiatric and neurological diseases. Because of the lack of treatment procedures that are medication free and without severe side effects, transcranial direct current stimulation (tDCS) and aerobic exercise (AE) have been tested to explore the potential for initiating and modulating neuroplasticity in the human brain. Both tDCS and AE could support cognition and behavior in the clinical and non-clinical context to improve the recovery process within neurological or psychiatric conditions or to increase performance. As these techniques still lack meaningful effects, although they provide multiple beneficial opportun…

The relationship between genetic risk variants with brain structure and function in bipolar disorder: A systematic review of genetic-neuroimaging stu…

2017

Genetic-neuroimaging paradigms could provide insights regarding the pathophysiology of bipolar disorder (BD). Nevertheless, findings have been inconsistent across studies. A systematic review of gene-imaging studies involving individuals with BD was conducted across electronic major databases from inception until January 9th, 2017. Forty-four studies met eligibility criteria (N = 2122 BD participants). Twenty-six gene variants were investigated across candidate gene studies and 4 studies used a genome-wide association approach. Replicated evidence (i.e. in >2 studies) suggests that individuals with BD carrying the BDNF Val66Met risk allele could have reduced hippocampal volumes compared …

The interface of clinical psychopharmacology and psychopathology.

1989

Four areas of common interest for clinical psychopharmacology and psychopathology are identified: (1) the diagnostic-based approach in clinical psychopharmacology; (2) the characterization of psychotropic drugs according the main psychopathologically defined target symptoms; (3) prediction of treatment response; (4) development of rating scales. The current state of research strategies in these areas is discussed and the need for new strategies is stressed. In particular, diagnosis-based research strategies in clinical psychopharmacology are not fully justified by empirical data; an alternative approach is discussed.

Attention deficit hyperactivity disorder subtypes: Are there differences in academic problems?

1995

This article addresses the relationship between attention deficit hyperactivity disorder (ADHD) and academic problems. The development of diagnostic categories of attention deficits from the Diagnostic and Statistical Manual of Mental Disorders (3rd ed.) to the Diagnostic and Statistical Manual of Mental Disorders (4th ed.) is briefly reviewed. Forty‐five Chilean children demonstrating symptoms of either ADHD Combined Type, ADHD Predominantly Inattentive Type, or ADHD Predominantly Hyperactivity‐Impulsive Type are compared with each other and with a clinical control group on the prevalence of academic achievement problems. The data show that academic problems are more common among ADHD Comb…

Project DyAdd: Non-linguistic Theories of Dyslexia Predict Intelligence

2020

Two themes have puzzled the research on developmental and learning disorders for decades. First, some of the risk and protective factors behind developmental challenges are suggested to be shared and some are suggested to be specific for a given condition. Second, language-based learning difficulties like dyslexia are suggested to result from or correlate with non-linguistic aspects of information processing as well. In the current study, we investigated how adults with developmental dyslexia or ADHD as well as healthy controls cluster across various dimensions designed to tap the prominent non-linguistic theories of dyslexia. Participants were 18–55-year-old adults with dyslexia (n = 36), …

Why are out-of-body experiences interesting for philosophers?

2009

After decades of only sparse scientific interest, we are currently witnessing a renaissance of empirical research into out-of-body experiences (OBEs) and full-body illusions. Being a philosopher of mind, I obviously have only a limited judgment of how good this research actually is from a purely scientific point of view. What I can do, however, is to draw attention to a series of theoretical aspects that make OBEs a particularly relevant target of investigation in the ongoing search for the neural correlate of self-consciousness and in the wider context of an empirically grounded theory of the human mind. Firstly, and most basically, this type of research has a great potential for conceptua…

Sexuality and Dissent in Fernando Arrabal’s Work

2020

En este artículo pretendemos analizar la presencia y la importancia de las sexualidades no normativas, o que escapan a la función reproductora, en la obra de Fernando Arrabal, autor español, nacido en Melilla en 1932, “desterrado” en París, donde vive desde 1955. El trabajo está dividido en tres partes: en la primera, expondremos la relación que existe entre Eros y Thanatos para dilucidar las relaciones que se establecen entre erotismo y pulsión de muerte, entre amor y sufrimiento en su obra; en la segunda parte, abordaremos el Deseo homosexual para exponer los aspectos narcisistas y sadomasoquistas del mismo que aparecen en la creación arrabaliana; en la última parte, titulada Placeres fál…