Search results for "Race"

showing 10 items of 4458 documents

Hepatitis E virus in lettuce and water samples: A method-comparison study

2017

The hepatitis E virus (HEV), which is an increasing cause of acute viral hepatitis in Europe, is a zoonotic virus that is mainly transmitted through contaminated water, consumption of raw or undercooked meat from pigs or wild boar, blood transfusion, and organ transplantation. Although the role of HEV transmission through contaminated produce has not been confirmed, the presence of HEV has been reported in irrigation waters and in vegetables. The present study used a World Health Organization (WHO) international standard and clinical samples to evaluate the performance characteristics of three RT-qPCR assays for detection and quantification of HEV. Two of the evaluated assays provided good …

0301 basic medicineVeterinary medicineIrrigationMeatSwine030106 microbiologySewageReal-Time Polymerase Chain Reactionmedicine.disease_causeMicrobiology03 medical and health sciencesWild boarHepatitis E virusSpinacia oleraceabiology.animalPepperVegetablesHepatitis E virusmedicineAnimalsHumansDetection limitbiologySewagebusiness.industryWater PollutionRT-qPCRGeneral MedicineLettuceContaminationIrrigation watermedicine.diseaseHepatitis EEuropeHEVRNA ViralCapsicumViral hepatitisbusinessFoodborne virusFood Science
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The Relationship between Diet and Frailty in Aging

2019

The increase in lifespan in the 20th century entails an increase in the elderly population. This brings a new challenge for society, causing people to have physical and mental limitations caused by age-related diseases, such as frailty. Frailty is clinically characterized by multisystem pathophysiological processes, such as chronic inflammation, immune activation, dysregulation of the musculoskeletal and endocrine systems, oxidative stress, energy imbalances, mitochondrial dysfunction, and sarcopenia. The elderly should consume energy in amounts close to those in what is currently accepted as a balanced diet. However, an increase in protein intake may be recommended for elderly people as l…

0301 basic medicineVitaminGerontologyAgingFrail ElderlyEndocrinology Diabetes and MetabolismNutritional Status030209 endocrinology & metabolismInflammationmedicine.disease_causeEating03 medical and health scienceschemistry.chemical_compound0302 clinical medicineNutraceuticalmedicineAnimalsHumansImmunology and AllergyEndocrine systemAgedAged 80 and overFrailtybusiness.industrymedicine.diseaseComorbidityDiet030104 developmental biologyHuman nutritionchemistrySarcopeniaDiet Healthymedicine.symptomEnergy IntakebusinessOxidative stressEndocrine, Metabolic & Immune Disorders - Drug Targets
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Vitamin A Deficiency and the Lung.

2018

Vitamin A (all-trans-retinol) is a fat-soluble micronutrient which together with its natural derivatives and synthetic analogues constitutes the group of retinoids. They are involved in a wide range of physiological processes such as embryonic development, vision, immunity and cellular differentiation and proliferation. Retinoic acid (RA) is the main active form of vitamin A and multiple genes respond to RA signalling through transcriptional and non-transcriptional mechanisms. Vitamin A deficiency (VAD) is a remarkable public health problem. An adequate vitamin A intake is required in early lung development, alveolar formation, tissue maintenance and regeneration. In fact, chronic VAD has b…

0301 basic medicineVitamincollagenLung DiseasesEpithelial-Mesenchymal Transitionextracellular matrixRetinoic acidlcsh:TX341-641Reviewepithelial–mesenchymal transitionlungExtracellular matrix03 medical and health scienceschemistry.chemical_compound0302 clinical medicineRisk Factorsretinoic acidMedicineAnimalsHumans030212 general & internal medicineVitamin AN-cadherinpulmonary diseaseNutrition and DieteticsLungbusiness.industryVitamin A DeficiencyRegeneration (biology)RetinolE-cadherinMicronutrientmedicine.diseaseVitamin A deficiency030104 developmental biologymedicine.anatomical_structureE-cadherin N-cadherin Vitamin A deficiency collagen epithelial–mesenchymal transition extracellular matrix lung pulmonary disease retinoic acid retinolchemistryImmunologyAirway Remodelingbusinesslcsh:Nutrition. Foods and food supplyFood ScienceretinolSignal Transduction
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CO2 flux emissions from the Earth's most actively degassing volcanoes, 2005-2015

2019

AbstractThe global carbon dioxide (CO2) flux from subaerial volcanoes remains poorly quantified, limiting our understanding of the deep carbon cycle during geologic time and in modern Earth. Past attempts to extrapolate the global volcanic CO2 flux have been biased by observations being available for a relatively small number of accessible volcanoes. Here, we propose that the strong, but yet unmeasured, CO2 emissions from several remote degassing volcanoes worldwide can be predicted using regional/global relationships between the CO2/ST ratio of volcanic gases and whole-rock trace element compositions (e.g., Ba/La). From these globally linked gas/rock compositions, we predict the CO2/ST gas…

0301 basic medicineVolcanologylcsh:MedicineAtmospheric sciencesCarbon cycleVolcanic Gases03 medical and health scienceschemistry.chemical_compound0302 clinical medicine[SDU.STU.VO]Sciences of the Universe [physics]/Earth Sciences/Volcanologyeventlcsh:Scienceevent.disaster_typeCarbon dioxide in Earth's atmospheregeographyMultidisciplinarygeography.geographical_feature_categoryAtmospheric carbon dioxidelcsh:RTrace elementFOS: Earth and related environmental sciencesVolcanologyGeochemistry030104 developmental biologyVolcanochemistry[SDU]Sciences of the Universe [physics]Carbon dioxideSubaerialEnvironmental scienceVolcanoeslcsh:Q030217 neurology & neurosurgeryvolcanic gas fluxes voclanoes
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C3 Drives Inflammatory Skin Carcinogenesis Independently of C5

2021

Nonmelanoma skin cancer such as cutaneous squamous cell carcinoma (cSCC) is the most common form of cancer and can occur as a consequence of DNA damage to the epithelium by UVR or chemical carcinogens. There is growing evidence that the complement system is involved in cancer immune surveillance; however, its role in cSCC remains unclear. Here, we show that complement genes are expressed in tissue from patients with cSCC, and C3 activation fragments are present in cSCC biopsies, indicating complement activation. Using a range of complement-deficient mice in a two-stage mouse model of chemically-induced cSCC, where a subclinical dose of 7,12-dimethylbenz[a]anthracene causes oncogenic mutatio…

0301 basic medicineWT wild typeSkin NeoplasmsComplement receptorComplement Membrane Attack Complexmedicine.disease_causeBiochemistrychemistry.chemical_compoundMice0302 clinical medicineCR complement receptorComplement ActivationSkinMice KnockoutcSCC cutaneous squamous cell carcinomaComplement C5Complement C3Receptors Complement030220 oncology & carcinogenesisCarcinoma Squamous CellDisease ProgressionTumor BiologyOriginal ArticleMAC membrane attack complexSignal TransductionHPV16 human papillomavirus type 16910-Dimethyl-12-benzanthraceneTPA 12-O-tetradecanoylphorbol-13-acetateMice TransgenicDermatologySettore MED/08 - Anatomia Patologica03 medical and health sciencesmedicineAnimalsHumansC3Molecular BiologyReceptor Anaphylatoxin C5aDMBA 712-dimethylbenz[a]anthracenebusiness.industry712-Dimethylbenz[a]anthraceneCancerCell BiologyNeoplasms Experimentalmedicine.diseaseComplement systemDisease Models Animal030104 developmental biologychemistryTumor progressionCancer researchCarcinogensTumor EscapeSkin cancerbusinessCarcinogenesisComplement membrane attack complexSkin carcinogenesis.EC epithelial cell
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Draft genomic sequence of Nereida ignava CECT 5292T, a marine bacterium of the family Rhodobacteraceae

2016

Nereida ignava strain 2SM4T (= CECT 5292T = DSM 16309T = CIP 108404T = CCUG 49433T) is a marine bacterium belonging to the Roseobacter group of the family Rhodobacteraceae within the class Alphaproteobacteria. The strain was isolated from sea water surrounding cultivated oysters 2–3 miles off the Mediterranean coast near Valencia (Spain) and was phylogenetically related to uncultured clones of gall symbiont bacteria of some species of Prionitis alga. Here we describe the genome sequence and annotation of this organism, the type strain of the single species of this genus. The genome comprised 2,888,349 bp, 2,872 protein-coding genes and 52 RNA genes. The annotation revealed the capacity to p…

0301 basic medicineWhole genome sequencingGeneticsbiologyNereida ignavaSlightly halophilicStrain (biology)Marine bacteria030106 microbiologyRoseobacterbiology.organism_classificationGenomeShort Genome ReportMicrobiology03 medical and health sciences030104 developmental biologyMarine bacteriophageBacteriocinStrictly aerobicMediterranean SeaGeneticsRhodobacteraceaeRhodobacteraceaeGeneStandards in Genomic Sciences
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Draft genome sequence of Thalassobius gelatinovorus CECT 4357 T , a roseobacter with the potential ability to degrade polycyclic aromatic hydrocarbons

2017

Abstract Thalassobius gelatinovorus is a member of the family Rhodobacteraceae previously classified in the genera Agrobacterium and Ruegeria . Strain Ahrens B6 T (= ATCC 25655 T , = B6 T , = CECT 4357 T , = CIP 105976 T , = DSM 5887 T , = IAM 12617 T , = JCM 20688 T , = KCTC 22092 T , = LMG 129 T , = NBRC 15761 T , = NCIMB 2206 T ) was isolated in 1967 from a sea water sampled in Kiel Fjord in Baltic Sea. Genomic DNA sequence of T. gelatinovorus CECT 4357 T was assembled into a draft genome and annotated. Here we report the main features of this draft genome composed by 3,902,797 bp arranged in 30 contigs with a G + C content of 58.4%, 3770 protein coding genes, 44 tRNA genes, 7 rRNA genes…

0301 basic medicineWhole genome sequencingbiologyRuegeria030106 microbiologyRibosomal RNARoseobacterbiology.organism_classificationGenome03 medical and health sciencesgenomic DNA030104 developmental biologyBiochemistryGeneticsRhodobacteraceaeGeneGene Reports
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Draft genome sequence of Shimia marina CECT 7688T

2016

Shimia marina is a member of the family Rhodobacteraceae described in 2006. Strain CL-TA03(T) (=CECT 7688(T)) was isolated from a biofilm formed on an acrylic slide submerged in surface water in a coastal fish farm in Tongyeong, Korea. Here we report the draft genome sequence and annotation of S. marina CECT 7688(T) which is composed by 4,001,860bp arranged in 45 scaffolds with a G+C content of 57.4%, 3878 protein coding genes, 40 tRNA genes, 4 rRNA genes and 1 repeat region. An overview of annotated genes revealed diverse genes encoding for exopolysaccharide and capsular biosynthesis enzymes, secondary metabolite biosynthesis enzymes, multiple antibiotic and metal resistance and the abilit…

0301 basic medicineWhole genome sequencingchemistry.chemical_classificationBase Composition030102 biochemistry & molecular biologybiologyBiofilmMolecular Sequence AnnotationSequence Analysis DNAAquatic ScienceRibosomal RNAbiology.organism_classificationMicrobiology03 medical and health sciences030104 developmental biologyMolecular Sequence AnnotationEnzymechemistryRepublic of KoreaTransfer RNAGeneticsRhodobacteraceaeRhodobacteraceaeGeneGenome BacterialMarine Genomics
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Et tu, Brute? Not Even Intracellular Mutualistic Symbionts Escape Horizontal Gene Transfer

2017

Many insect species maintain mutualistic relationships with endosymbiotic bacteria. In contrast to their free-living relatives, horizontal gene transfer (HGT) has traditionally been considered rare in long-term endosymbionts. Nevertheless, meta-omics exploration of certain symbiotic models has unveiled an increasing number of bacteria-bacteria and bacteria-host genetic transfers. The abundance and function of transferred loci suggest that HGT might play a major role in the evolution of the corresponding consortia, enhancing their adaptive value or buffering detrimental effects derived from the reductive evolution of endosymbionts' genomes. Here, we comprehensively review the HGT cases recor…

0301 basic medicine[SDV.OT]Life Sciences [q-bio]/Other [q-bio.OT]Adaptive valuelcsh:QH426-470transfert horizontal de gènenutritional symbiosisReviewBiologyGenome03 medical and health sciencesGeneticshorizontal gene transfer (HGT);insects;integrative evolution;intracellular bacteria;nutritional symbiosishorizontal gene transfer (HGT)insectsGenetics (clinical)Endosymbiotic bacteriaEcologyintracellular bacteriaIntracellular parasiteinsectatransformation intégrativeintegrative evolutionlcsh:Genetics030104 developmental biologyEvolutionary biologyHorizontal gene transferbactérie intracellulairesymbioseFunction (biology)Autre (Sciences du Vivant)
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Modulation of Intracellular O-2 Concentration in Escherichia coli Strains Using Oxygen Consuming Devices

2018

International audience; The use of cell factories for the production of bulk and value-added compounds is nowadays an advantageous alternative to the traditional petrochemical methods. Nevertheless, the efficiency and productivity of several of these processes can improve with the implementation of micro-oxic or anoxic conditions. In the industrial setting, laccases are appealing catalysts that can oxidize a wide range of substrates and reduce O-2 to H2O. In this work, several laccase-based devices were designed and constructed to modulate the intracellular oxygen concentration in bacterial chassis. These oxygen consuming devices (OCDs) included Escherichia coil's native laccase (CueO) and …

0301 basic medicine[SDV]Life Sciences [q-bio]030106 microbiologyBiomedical Engineeringchemistry.chemical_elementmedicine.disease_causeBiochemistry Genetics and Molecular Biology (miscellaneous)Oxygenlaccase03 medical and health sciencesIn vivomedicineEscherichia coliEscherichia coliLaccasebacterial chassisoxygen consuming devicesGeneral MedicineDirected evolutionAnoxic watersQR030104 developmental biologychemistryBiochemistryTALimiting oxygen concentrationsynthetic biologyIntracellular
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