Search results for "Rao"

DECORIN EFFECTS ON PROTEOMIC PROFILING OF BREAST CANCER CELLS: AN UPDATED STUDY

2015

The malignant carcinomas are characterized by several capabilities acquired by the neoplastic cells, among which the ability to invade the extracellular matrix (ECM) and to establish a crosstalk with several ECM components. Under this respect, the extracellular microenvironment is an entity extraordinarily rich of information with opposite signals. Our group has long undertaken the study of the effects of ECM molecules on the behavior of cancer cells in vitro. Among the studied molecules, the decorin was found to exert a non-permissive effect on the growth and motility of the transfected tumor cells. The decorin, belongs to the family of small leucine-rich proteoglycans (SLRP) and is involv…

Safety and efficacy of changing to the travoprost/timolol maleate fixed combination (DuoTrav) from prior mono- or adjunctive therapy.

2010

Norbert Pfeiffer1, Maria-Luise Scherzer2, Hubert Maier3, Sonja Schoelzel4, Mark C Jasek5, Jeanette A Stewart6, William C Stewart6 On behalf of the DuoTravMED study group1Johannes Gutenberg-Universität Mainz, Mainz, Germany; 2Regenstauf, Germany; 3Gerolzhofen, Germany; 4Institutes of Molecular Medicine, University of Freiburg, Department of Surgery, Freiburg, Germany; 5Alcon Laboratories, Inc., Fort Worth, TX, USA; 6PRN Pharmaceutical Research Network, LLC, Charleston, SC, USAPurpose: To assess the safety and efficacy of changing to the travoprost/timolol fixed combination (TTFC) from other mono- or adjunctive therapies.Patients and methods: A prospective, open-label, observational …

Sources of carbon and dietary habits of new Lessepsian entry Brachidontes pharaonis (Bivalvia, Mytilidae) in the western Mediterranean

2003

The sources of carbon and the dietary habits of Brachidontes pharaonis (Mollusca, Bivalvia), a new Lessepsian entry in the western Mediterranean, living in a cooling vat of a saltworks system in western Sicily (MED), were assessed by estimating throughout a season the relative abundance of a stable carbon isotope (δ13C) in particulate organic matter (POM), sedimentary organic matter (SOM), primary organic matter sources (seagrasses, sand microflora, macroalgae), Brachidontes pharaonis and its biodeposition material. In the saltworks the most enriched primary food source potentially fuelling the saltworks food web was Cymodocea nodosa (seasonal average -7.9±0.6‰), Laurencia papillosa and Cys…

[The role of the anesthesiologist in secondary hyperparathyroidism].

2010

In the last years the increasing of diabetes and hypertension has produced a considerable increase of patients with chronic renal failure; secondary hyperparathyroidism is one of the major complications. The resection of hyperfunctioning parathyroid tissue is the ultimate goal of the treatment. The preoperative examination by the anesthetist is the starting-point of the treatment. The anesthetist programs hemodialysis, the correction of fluid and electrolyte abnormalities and of the anaemia. In the operating room the anesthetist is involved in the careful monitoring of liquid infusion and anesthesiological procedure. The intraoperative parathyroid hormone (PTH) assay is an essential tool be…

Simulation methods to evaluate and optimize optical designs in order to improve the presbyopia correction

2014

El envejecimiento tiene dos grandes consecuencias en la visión, la presbicia y las cataratas. La presbicia es el resultado de la declinación natural, relacionada con la edad, de la capacidad para enfocar objetos cercanos. Existe una gran población présbita, en edades comprendidas entre los 45 y 65 años. Las cataratas se producen en personas mayores como resultado natural del proceso del envejecimiento, causando una pérdida de visión debido a la opacificación del cristalino. La cirugía de cataratas es la cirugía más habitual en oftalmología, pero también la intervención quirúrgica, no sólo ocular, más practicada a nivel mundial. Un 30% de la población mayor de 65 años presenta algún tipo de …

Evaluation of Diethyl Carbonate and Methyl Isobutyl Ketone as Entrainers for the Separation of 1-Hexene and n-Hexane

2017

Diethyl carbonate and methyl isobutyl ketone are tested as possible entrainers for separating 1-hexene and n-hexane by extractive distillation. For this purpose, isobaric vapor–liquid equilibrium (VLE) data at 100 kPa have been obtained for the two ternary systems formed by the two hydrocarbons and one of the selected solvents: 1-hexene + n-hexane + diethyl carbonate and 1-hexene + n-hexane + methyl isobutyl ketone. VLE data for the following constituent binary systems have also been determined: 1-hexene + diethyl carbonate, n-hexane + diethyl carbonate, 1-hexene + methyl isobutyl ketone, and finally n-hexane + methyl isobutyl ketone. All binary systems present moderate positive deviations …

Gall de cua forcada, Perdiu blanca, Gallo lira (VER0000086)

Altres noms vulgars: Black Grouse (Anglès), Tétras lyre (Francès), Birkhuhn (Alemany) Gabinet de Vertebrats (Departament de Zoologia), Facultat de Ciències Biològiques (Campus de Burjassot), C/ Doctor Moliner, s/n, Bloque B. 5é plant, Burjassot (Valencia). Armari: 1-2 Macho

Career experts' conceptions of systems development in lifelong guidance

2023

AbstractThis article reports the findings from a phenomenographic study of career experts’ conceptions of systems development in lifelong guidance settings. The results show that conceptions of systems development in lifelong guidance varied from minimal, aspirational, strategic to systemic. By exploring the logical relationship between qualitatively different conceptions, it provides policymakers and other stakeholders with a way of holistically viewing the varying levels of lifelong guidance systems development. The matrix presented in this article may serve as a catalyst for reflection on crucial elements, such as legislation, leadership and cooperation, that have the potential to improv…

Temporal multiplexing with adaptive optics for simultaneous vision.

2016

We present and test a methodology for generating simultaneous vision with a deformable mirror that changed shape at 50 Hz between two vergences: 0 D (far vision) and −2.5 D (near vision). Different bifocal designs, including toric and combinations of spherical aberration, were simulated and assessed objectively. We found that typical corneal aberrations of a 60-year-old subject changes the shape of objective through-focus curves of a perfect bifocal lens. This methodology can be used to investigate subjective visual performance for different multifocal contact or intraocular lens designs.

Kosteneffektivitätsanalyse der Versorgung von Kataraktpatienten mit monofokalen Intraokularlinsen aus Sicht der Leistungserstatter

2003

BACKGROUND Data on the cost effectiveness of cataract surgery with respect to the German statutory health insurance system are hardly available. Hence the increase in visual acuity as primary efficacy endpoint, order of posterior capsule opacification as primary complication endpoint and direct cost for supplementation with monofocal intraocular lenses have been assessed via meta-analyses to evaluate the procedure's cost effectiveness from the perspective of the German statutory health insurance system. MATERIAL AND METHODS Using the medical internet database MEDLINE two meta-analyses on publications between 1995 and 2002 were carried out, one estimating the gained increase in visual acuity…