Search results for "STAGE"
showing 10 items of 1393 documents
Proteomics of foodborne trematodes
2011
Abstract Food-borne trematodiases are among the most neglected tropical diseases, not only in terms of research funding, but also in the public media. The Trematoda class contains several species identified as the causal agents of these diseases whose biological cycle, geographical distribution and epidemiology have been well characterised. The diagnosis of these diseases is based on parasitological techniques and only a limited number of drugs are currently available for treatments, most of which are unspecific. Therefore, in-depth studies to identify new and specific targets for both effective diagnosis and treatments are urgently needed. Currently, little molecular information is availab…
Phloem and xylem flow contributions to nectarine fruit development
2021
This study aimed at determining how source-sink balance and phloem/xylem flows affect nectarine fruit growth during development. Different levels of water and assimilate availability to growing fruits were induced in vivo by varying leaf:fruit ratio (L:F) of fruiting shoots and by interrupting the phloem stream (girdling) at the base of entire fruiting shoots. Two fruiting shoots in each of six ‘Big Top’ adult nectarine trees were selected, labeled and their L:F was adjusted by thinning fruits or removing leaves to two levels: high L:F and low L:F. Stem water potential, stomatal conductance, continuous fruit diameter and leaf turgor pressure were measured before and after girdling at stage …
ICPM NEWS: The European Training Network ETUDE (Encompassing Training in Functional Disorders across Europe) Is Recruiting 15 Early-Stage Researchers
2021
The European Training Network ETUDE (Encompassing Training in fUnctional Disorders across Europe): a new research and training program of the EURONET…
2021
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The Influence of Pubertal Development on Adolescent Depression: The Mediating Effects of Negative Physical Self and Interpersonal Stress
2021
The current study examined the influence of pubertal development stage on depression and its psychosocial mechanisms in a non-clinical population of 502 adolescents (244 boys and 258 girls) in China, graded 5 to 8. Results indicated that (1) pubertal development was positively correlated with depression, negative physical self and interpersonal stress. (2) There is a significant gender by pubertal development interaction on the measure of academic self-concept, which is accounted for by decreased academic self in boys but not in girls as a function of pubertal development. (3) Mediation analyses show that increased depression in late compared to pre- puberty is partly mediated by the enhanc…
Fourth Graders' Social Standing with Peers: A Prospective Study on the Role of First Grade Physical Activity, Weight Status, and Motor Proficiency
2010
We prospectively examined the role of physical activity involvement, weight status, and motor functioning capability in 1st grade for social status among other pupils in class in the 4th grade. Our sample included 80 Norwegian 1st grade pupils (Girls N = 44; Boys N = 36). 1st grade motor proficiency and objectively measured physical activity, but not weight status was predictive of 4th grade social standing among pupils in class as measured by socio‐metric status. Interaction findings also revealed that 1st grade healthy weight children being proficient in the motor domain benefit more in terms of their social standing among peers in 4th grade than do 1st grade overweight but equally motor …
Metabolic syndrome, insulin resistance and sleepiness in real-life obstructive sleep apnoea.
2011
The metabolic syndrome shows a variable prevalence in obstructive sleep apnoea (OSA), and its association with insulin resistance or excessive daytime sleepiness in OSA is unclear. This study assessed the following in consecutive patients with newly diagnosed OSA: 1) the prevalence of metabolic syndrome; and 2) its association with insulin resistance and daytime sleepiness. Metabolic syndrome (National Cholesterol Education Program Adult Treatment Panel (NCEP- ATP) III criteria), insulin resistance (Homeostatic Model Assessment (HOMA) index, n5288) and daytime sleepiness (Epworth Sleepiness Scale) were assessed in 529 OSA patients. The prevalence of metabolic syndrome was 51.2%, which incre…
Obstructive sleep apnea and chronic kidney disease: open questions on a potential public health problem
2018
To determine the relationship between obstructive sleep apnea (OSA) and chronic kidney disease (CKD). Previous population studies of the association are sparse, conflicting and confined largely to studies of administrative data.Cross-sectional analysis in unselected participants of the Men Androgens Inflammation Lifestyle Environment and Stress (MAILES) study, aged40 years. Renal data were available for 812 men without a prior OSA diagnosis who underwent full in-home polysomnography (Embletta X100) in 2010-2011. CKD was defined as an estimated glomerular filtration rate (eGFR)60 mL/min/1.73m2 or eGFR≥60 and albuminuria (albumin-creatinine ratio ≥3.0 mg/mmol).CKD (10.5%, n = 85 [Stage 1-3, 9…
Quelle place reste-t-il pour la chirurgie dans les cancers bronchiques de stade IIIA-N2 ?
2015
Resume Introduction Le cancer bronchique non a petites cellules (CBNPC) demeure un probleme de sante majeur, avec une survie globale a 5 ans des stades IIIA de l’ordre de 25 %. La prise en charge chirurgicale des CBNPC de stade IIIA demeure cependant controversee. Nous avons donc evalue les differentes strategies de prise en charge des CBNPC de stade IIIA-N2. Methodes De janvier 1990 a decembre 2013, les essais controles randomises evaluant la survie des patients traites par chimiotherapie d’induction suivie d’une resection chirurgicale vs chirurgie seule, et ceux evaluant la survie des patients traites par radio- ou chimiotherapie d’induction suivie d’une resection chirurgicale vs la combi…
Factors predicting poor survival after lung-sparing radical pleurectomy of IMIG stage III malignant pleural mesothelioma.
2012
OBJECTIVES: The role of radical pleurectomy (RP) in the management of IMIG stage III in malignant pleural mesothelioma (MPM) remains controversial. The aim of the study was to investigate the feasibility and outcome as well as to determine factors predicting poor survival. METHODS: Patients having IMIG stage III MPM were identified within a prospective multimodality treatment study (RP followed by chemoradiation) between 2002 and 2010 at a single institution. Kaplan–Meier analyses, log-rank test and Cox regression analyses were used to estimate survival and to determine predictors of survival. RESULTS: A total of 78 patients (66.3 ± 2.5 years, 65 males) underwent RP followed by chemoradiati…