Search results for "Scutella"

showing 10 items of 28 documents

Inhibition of Trypanosoma cruzi growth by medical plant extracts

2002

This study describes the screening of extracts obtained from 18 plants and two fungi used in the Chinese and Mediterranean traditional medicines on epimastigote forms of Trypanosoma cruzi. The extracts were tested against epimastigote of T. cruzi Bra C15C2 clone in vitro at 27 degrees C and at a concentration of 250 microg/ml in axenic culture. Angelica dahurica, A. pubescens, A. sinensis, Astragalus membranaceus, Coptis chinensis, Haplophyllum hispanicum, Phellodendron amurense, Poria cocos, Ranunculus sceleratus and Scutellaria baicalensis showed significant effects against the parasite with a percentage of growth inhibition between 20 and 100%. C. chinensis and R. sceleratus showed the g…

MaleTrypanosoma cruziPharmacognosyInhibitory Concentration 50chemistry.chemical_compoundDrug DiscoveryLeukocytesAnimalsRanunculus sceleratusMedicine Chinese TraditionalRats WistarTrypanosoma cruziPharmacologyPlants MedicinalDose-Response Relationship DrugbiologyTraditional medicineMediterranean RegionPlant ExtractsAngelica dahuricaFungiGeneral MedicineAstragalus propinquusCoptis chinensisbiology.organism_classificationRatsLogistic ModelschemistryPhellodendron amurenseScutellaria baicalensisMedicine TraditionalGrowth inhibitionFitoterapia
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Antioxidant activity of anti-inflammatory plant extracts

2002

The antioxidant properties of twenty medical herbs used in the traditional Mediterranean and Chinese medicine were studied. Extracts from Forsythia suspensa, Helichrysum italicum, Scrophularia auriculata, Inula viscosa, Coptis chinensis, Poria cocos and Scutellaria baicalensis had previously shown anti-inflammatory activity in different experimental models. Using free radical-generating systems H. italicum. I. viscosa and F. suspensa protected against enzymatic and non-enzymatic lipid peroxidation in model membranes and also showed scavenging property on the superoxide radical. All extracts were assayed at a concentration of 100 microg/ml. Most of the extracts were weak scavengers of the hy…

MaleXanthine OxidaseErythrocytesAntioxidantmedicine.drug_classmedicine.medical_treatmentHelichrysum italicumAntioxidantsGeneral Biochemistry Genetics and Molecular BiologyAnti-inflammatoryRats Sprague-DawleyLipid peroxidationchemistry.chemical_compoundmedicineAnimalsGeneral Pharmacology Toxicology and PharmaceuticsXanthine oxidaseForsythia suspensaPlants MedicinalbiologyTraditional medicineDeoxyribosePlant ExtractsAnti-Inflammatory Agents Non-SteroidalFree Radical ScavengersGeneral MedicineCoptis chinensisbiology.organism_classificationRatsBiochemistrychemistryMicrosomes LiverScutellaria baicalensisLipid PeroxidationMedicine TraditionalAminopyrine N-DemethylaseLife Sciences
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Antifeedant activity of neoclerodane diterpenoids from two Sicilian species of Scutellaria

2002

Mamestra brassicaePieris brassicaebiologyBotanyScutellarialanguageLamiaceaebiology.organism_classificationSpodoptera littoralisBiochemistrySicilianEcology Evolution Behavior and Systematicslanguage.human_languageBiochemical Systematics and Ecology
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Occurrence of acid and neutral carboxypeptidases in germinating cereals

1986

High neutral metallocarboxypeptidase activity (EC 3.4.17) has earlier been detected in young seedlings of rice (Oryza sativa L.) using benzyloxycarbonyl-L-phenylalanyl-L-alanine (Z-Phe-Ala) as substrate at pH 7. This finding was confirmed, and it was observed that the activity could be assayed with higher specificity and sensitivity by using Z-Gly-Ala or Z-Gly-Phe as substrate at pH 6.5–7. No corresponding activity was detected in seedlings of barley (Hordeum vulgare L. cv. Himalaya), oats (Avena sativa L.) or maize (Zea mays L.). The seedlings of the four cereals possessed similar activities of acid carboxypeptidases (EC 3.4.16; hydrolysis of Z-Phe-Ala and Z-Ala-Phe at pH 5.2 and of Z-Ala-…

Oryza sativafood.ingredientbiologyPhysiologyChemistryfood and beveragesCell BiologyPlant ScienceGeneral MedicineMetallocarboxypeptidase activityCarboxypeptidaseCarboxypeptidase activityHorticultureAvenafoodScutellaBotanyGeneticsbiology.proteinPoaceaeHordeum vulgarePhysiologia Plantarum
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Analysis of Essential Oils from Scutellaria orientalis ssp. alpina and S. utriculata by GC and GC-MS

2011

The chemical composition of the essential oils obtained from aerial parts of Scutellaria orientalis L. ssp. alpina (Boiss.) O. Schwarz and S. utriculata Labill. growing wild in Lebanon, were analyzed by GC and GC-MS. In S. orientalis ssp. alpina, strongly characterized by sesquiterpenes (41.2%) and particularly sesquiterpene hydrocarbons (31.7%), hexahydrofarnesylacetone (11.7%) was recognized as the main constituent, together with hexadecanoic acid (7.6%), caryophyllene (7.4%), caryophyllene oxide (6.8%), 4-vinylguaiacol (5.4%) and germacrene D (5.4%). S. utriculata oil was instead constituted above all by monoterpenes (42.2%), particularly oxygen containing monoterpenes (39.9%), and in t…

PharmacologyScutellaria orientalisCaryophyllenePlant ScienceGeneral MedicineSesquiterpenechemistry.chemical_compoundComplementary and alternative medicineLinaloolchemistryDrug DiscoveryBotanyGuaiacolGas chromatography–mass spectrometryChemical compositionGeraniolNatural Product Communications
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Minor diterpenoids from Scutellaria polyodon.

2000

Four minor neoclerodane diterpene constituents were isolated from the aerial parts of Scutellaria polyodon. These compounds were characterized as the new scupolins J (1) and K (2) and the previously known scutalpin O (3) and scutalsin.

PharmacologybiologyMolecular StructureChemistryStereochemistrySpectrum AnalysisOrganic ChemistryPharmaceutical SciencePlantsbiology.organism_classificationTerpenoidAnalytical Chemistrychemistry.chemical_compoundComplementary and alternative medicineDrug DiscoveryScutellariaMolecular MedicineHemiacetalDiterpeneDiterpenesJournal of natural products
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Volatile components and antifeedant activity of the essential oil from Scutellaria hastifolia L.

2009

PharmacologybiologyOrganic ChemistryPharmaceutical ScienceSettore CHIM/06 - Chimica Organicabiology.organism_classificationAnalytical Chemistrylaw.inventionComplementary and alternative medicineScutellaria hastifolia L.essential oil antifeedant activitylawDrug DiscoveryBotanyScutellariaMolecular MedicineEssential oil
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Volatile constituents of Scutellaria rubicunda Hornem subsp. linnaeana (Caruel) Rech. (Lamiaceae) endemic in Sicily

2006

PharmacologybiologyTraditional medicineCaryophylleneOrganic ChemistryVolatileScutellaria rubicunda HornemPharmaceutical Sciencebiology.organism_classificationBiochemistrylaw.inventionAnalytical Chemistrychemistry.chemical_compoundLinaloolchemistryComplementary and alternative medicinelawDrug DiscoveryBotanyScutellariaMolecular MedicineLamiaceaeSpodoptera littoralisEcology Evolution Behavior and SystematicsEssential oilPlanta Medica
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Neoclerodane Diterpenoids from Scutellaria pontica

1997

Seven novel neoclerodane diterpenoids, scupontins A-G, have been isolated from the Me2CO extract of the aerial parts of Scutellaria pontica (1-7), together with the known neoclerodanes scutalbin A and scutalpin M. Structures 1-7 were established by exhaustive NMR spectroscopic studies and chemical transformations. Scupontins A-D(1-4, respectively) and scupontins E (5)andF(6) possess unusual [(3¢S,3¢¢S)-3¢-[(3¢¢-acetoxybutyryl)oxy]butyryloxy and [(3¢S,3¢¢S,3¢¢¢S)- 3¢-[[3¢¢-[(3¢¢¢-hydroxybutyryl)oxy]butyryl]oxy]butyryl]oxy substituents, respectively, attached to the C-19 position of the neoclerodane framework. In the case of the 6R,7â-dibenzoate derivative 7 (scupontin G) its absolute config…

Pharmacologychemistry.chemical_classificationBicyclic moleculebiologyStereochemistryOrganic ChemistryAbsolute configurationPharmaceutical ScienceEpoxidebiology.organism_classificationAnalytical Chemistrychemistry.chemical_compoundComplementary and alternative medicinechemistryDrug DiscoveryScutellariaMolecular MedicineDiterpeneChirality (chemistry)Derivative (chemistry)LactoneJournal of Natural Products
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Neoclerodane Diterpenoids from Scutellaria polyodon

1997

Nine new neoclerodane diterpenoids, scupolins A−I, have been isolated from an Me2CO extract of the aerial parts of Scutellaria polyodon (3−11), together with the known neoclerodanes jodrellin B (1) and scutecolumnin A (2). Structures 3−11 were established by spectroscopic means and by comparison with closely related compounds.

Pharmacologychemistry.chemical_classificationbiologyStereochemistryOrganic ChemistryPharmaceutical ScienceEpoxidePharmacognosybiology.organism_classificationTerpenoidAnalytical Chemistrychemistry.chemical_compoundComplementary and alternative medicinechemistryDrug DiscoveryScutellariaMolecular MedicineOrganic chemistryHemiacetalDiterpeneLactoneJournal of Natural Products
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