Search results for "Simulation."
showing 10 items of 4779 documents
Generalized symmetries in nanostructure simulations
2009
The Impact of Financial Development and Macroeconomic Fundamentals on Nonperforming Loans among Emerging Countries: An Assessment Using the NARDL App…
2022
The relationship between financial development indicators and non-performing loans (NPLs) has garnered significant attention, especially in emerging countries. The puzzle of whether financial sector development increases or decreases Non-performing Loans (NPL)s has not been resolved to the satisfaction of the curious mind. This research attempts to answer the above question by studying the asymmetric and symmetric association between financial sector development and NPLs, by utilizing the novel non-linear autoregressive distribution lag (NARDL) and the linear autoregressive distribution lag (ARDL) approach. Moreover, to make the study inclusive, we have added a series of proxies to measure …
Synthesis and Structure-Affinity Relationships of Spirocyclic Benzopyrans with Exocyclic Amino Moiety
2019
σ1 and/or σ2 receptors play a crucial role in pathological conditions such as pain, neurodegenerative disorders, and cancer. A set of spirocyclic cyclohexanes with diverse O-heterocycles and amino moieties (general structure III) was prepared and pharmacologically evaluated. In structure-activity relationships studies, the σ1 receptor affinity and σ1:σ2 selectivity were correlated with the stereochemistry, the kind and substitution pattern of the O-heterocycle, and the substituents at the exocyclic amino moiety. cis-configured 2-benzopyran cis-11b bearing a methoxy group and a tertiary cyclohexylmethylamino moiety showed the highest σ1 affinity ( Ki = 1.9 nM) of this series of compounds. In…
Evaluation of asset replacement strategies considering economic cycles: lessons from the machinery rental business
2015
Contains fulltext : 144492.pdf (Publisher’s version ) (Open Access) In businesses with heavy capital investments, the effective management of assets is crucial, in particular in the fleet rental business where assets are the major source of revenues. One important question in this regard concerns the replacement of used assets and the purchase of new assets. Thus, the objective of this study is to evaluate performance effects of asset replacement strategies. In order to maximise net cash flow of a rental company for construction machinery, a range of scenarios investigating the timing and nature of policies for replacing the fleet are analysed. Simulation findings are then discussed to gene…
Modelling and assessing public health policies to counteract Italian measles outbreaks
2021
This study aims to understand, through explanatory research, the key factors that led to the 2017 measles outbreak in Italy, the causes of the low level of immunisation and the causes of possible cyclical phenomena of measles epidemics. This topic's comprehension has required a holistic approach, merging epidemiological aspects, socioeconomic aspects (including the evolution of mistrust in vaccinations, infodemy and fake news) and health law constraints. A specific SIR System Dynamics (SD) model was built to reproduce the relevant cause-and-effect relationships between social interactions, the public institutions behaviour and the measles outbreaks. SD results permit the assessment of the h…
Performance Management in Local Government: The Application of System Dynamics to Promote Data Use
2014
The purpose of this article is to demonstrate how system dynamics can be used to enrich performance management in local government, focusing specifically on how the development of conceptual and simulation system dynamic models can foster a shared view of the relevant system among stakeholders to overcome factors that limit data use. Responding to this purpose, we present a normative case study on how key drivers can be used to foster a shared view of the residential refuse collection system for supporting policy and process changes. A major finding from our research, however, is that performance management cannot overlook the broader forces of citizenship outcomes that impact the community.
Use of driving simulators for advanced driver assistance Systems evaluation in emergency situations
2012
Introducing advanced driver assistance systems in cars has numerous consequences, particularly on drivers' behavior and their interaction with the vehicle. The expected safety benefits of assistance systems can thus be jeopardized. In order to assess the actual safety benefits, driving simulators offer a safe and cheap alternative. This doctoral work relies on experiments carried out on driving simulators with different assistance systems. A first experimental part focuses on longitudinal control assistance: we studied drivers' familiarization with a Forward Collision Warning system in critical situations. A second experimental part focuses on lateral control assistance: we studied drivers'…
CERN IRRADIATION FACILITIES.
2017
CERN provides unique irradiation facilities for applications in dosimetry, metrology, intercomparison of radiation protection devices, benchmark of Monte Carlo codes and radiation damage studies to electronics.
Measuring Distraction at the Levels of Tactical and Strategic Control: The Limits of Capacity-Based Measures for Revealing Unsafe Visual Sampling Mod…
2011
The control theory of driving suggests that driver distraction can be analyzed as a breakdown of control at three levels. Common approach for analyzing distraction experimentally is to utilize capacity-based measures to assess distraction at the level of operational control. Three driving simulation experiments with 61 participants were organized to evaluate which kind of measures could be used to analyze drivers' tactical visual sampling models and the related effects of distraction while searching textual information on in-car display. The effects of two different text types were evaluated. The utilized capacity-based measures seemed to be insufficient for revealing participants' tactical…
Wastewater treatment: New insight provided by interactive multiobjective optimization
2011
In this paper, we describe a new interactive tool developed for wastewater treatment plant design. The tool is aimed at supporting the designer in designing new wastewater treatment plants as well as optimizing the performance of already available plants. The idea is to utilize interactive multiobjective optimization which enables the designer to consider the design with respect to several conflicting evaluation criteria simultaneously. This is more important than ever because the requirements for wastewater treatment plants are getting tighter and tighter from both environmental and economical reasons. By combining a process simulator to simulate wastewater treatment and an interactive mul…