Search results for "System P"
showing 10 items of 222 documents
An analysis methodology to evaluate the contribution to electrical security given by bare buried conductors in a system of intertied earthing grids
2004
The paper presents an analysis methodology for a single-line-to-ground fault, occurring at a secondary MV/LV substation in a power network formed by a HV/MV station, feeding, through a MV tri-phase cable line, N MV/LV substations whose earth electrodes are interconnected by bare buried conductors. In the preliminary explanation of the methodology, earth buried conductors are studied in their double function of earth electrodes and connection elements between earthing grids, both in absence and in presence of other interfering conductors. Subsequently analyzed is, with a distributed parameters approach, the system constituted by an earth buried conductor and a MV tri-phase cable line. The eq…
Activation of complement by the alternative pathway as a factor in the pathogenesis of periodontal disease.
1976
Dental plaque and a bacterium, Actinomyces viscosus, isolated from plaque that can reproduce periodontal disease in germ-free rats, are activators of complement by the alternative pathway. It is suggested that this process is involved in the pathogenesis of chronic inflammatory periodontal disease.
Host immune response to Cryptosporidium parvum infection
2010
Species of the genus Cryptosporidium are protozoan parasites (Apicomplexa) that cause gastroenteritis in animals and humans. Of these Cryptosporidium parvum and Cryptosporidium hominis are the major causative agents of human cryptosporidiosis. Whereas infection is self-limiting in the immunocompetent hosts, immunocompromised individuals develop a chronic, life-threatening disease. As specific therapeutic or preventive interventions are not yet available, better understanding of the immune response to the parasite is required. This minireview briefly summarizes the factors involved in the innate and acquired immune response in this pathogen-host interaction with an emphasis on more recent da…
A central nervous system-focused treatment approach for people with frozen shoulder: protocol for a randomized clinical trial
2019
Background: Frozen shoulder (FS) is a musculoskeletal condition of poorly understood etiology that results in shoulder pain and large mobility deficits. Despite some physical therapy interventions, such as joint mobilization and exercise, having shown therapeutic benefit, a definitive treatment does not currently exist. The aim of this study will be to compare the effectiveness of a central nervous system (CNS)-directed treatment program versus a standard medical and physical therapy care program on outcomes in participants with FS. Methods/design: The study is a two-group, randomized clinical trial with blinding of participants and assessors. Participants will be recruited via referrals fr…
On the pathogenesis of atherosclerosis: enzymatic transformation of human low density lipoprotein to an atherogenic moiety.
1995
Combined treatment with trypsin, cholesterol esterase, and neuraminidase transforms LDL, but not HDL or VLDL, to particles with properties akin to those of lipid extracted from atherosclerotic lesions. Single or double enzyme modifications, or treatment with phospholipase C, or simple vortexing are ineffective. Triple enzyme treatment disrupts the ordered and uniform structure of LDL particles, and gives rise to the formation of inhomogeneous lipid droplets 10-200 nm in diameter with a pronounced net negative charge, but lacking significant amounts of oxidized lipid. Enzymatically modified LDL (E-LDL), but not oxidatively modified LDL (ox-LDL), is endowed with potent complement-activating c…
PML nuclear body-residing proteins sequentially associate with HPV genome after infectious nuclear delivery.
2019
Subnuclear promyelocytic leukemia (PML) nuclear bodies (NBs) are targeted by many DNA viruses after nuclear delivery. PML protein is essential for formation of PML NBs. Sp100 and Small Ubiquitin-Like Modifier (SUMO) are also permanently residing within PML NBs. Often, large DNA viruses disassemble and reorganize PML NBs to counteract their intrinsic antiviral activity and support establishment of infection. However, human papillomavirus (HPV) requires PML protein to retain incoming viral DNA in the nucleus for subsequent efficient transcription. In contrast, Sp100 was identified as a restriction factor for HPV. These findings suggested that PML NBs are important regulators of early stages o…
Interactions and transformations of dissipative optical bullets
2007
Nonlinear dissipation provides distinctive dynamical properties to optical bullets. According to the system parameters, the dynamical properties of single bullets range from fully stable to pulsating and instable bullets. We are here interested in the following stage, namely the interaction between several optical bullets.
Molecular mechanisms of primary and secondary mucosal immunity using avian infectious bronchitis virus as a model system
2007
Although mucosal immune responses are critical for protection of hosts from clinical illness and even mortality caused by mucosal pathogens, the molecular mechanism of mucosal immunity, which is independent of systemic immunity, remains elusive. To explore the mechanistic basis of mucosal protective immunity, gene transcriptional profiling in mucosal tissues was evaluated after the primary and secondary immunization of animals with an attenuated avian infectious bronchitis virus (IBV), a prototype of Coronavirus and a well-characterized mucosal pathogen. Results showed that a number of innate immune factors including toll-like receptors (TLRs), retinoic-acid-inducible gene-1 (RIG-1), type I…
L’esperienza spagnola, dal terrorismo interno alla minaccia globale. Strumenti di difesa di una democrazia banco di prova
2017
The Spanish System represents a minor reality in a context in which Western European Democracies have opted to exclude from their Constitutions the preventive provision of the so‐called state of emergency and the specific case of terrorism. After all, the events that affected Spain are well‐known. Since many years, Spain has been active in the conflict against the Basque Terrorism and the democratic dilemmas, because of the presence in the Parliament of parties linked to the terrorist group Eta. And exactly the well‐known Ley organic sobre los partidos políticos 6/2002, which outlawed the Batasuna Party and other political organizations connected to the Eta group. Therefore, in the Spanish …
Badanie selektywności systemu podatkowego stanowiącego program pomocy – glosa do wyroku TSUE z dnia 16 marca 2021 r. w sprawie C-562/19 P Komisja Eur…
2021
Niniejszy artykuł ma na celu przedstawienie zagadnienia sposobu badania selektywności programu pomocy, który jest środkiem pomocy państwa w rozumieniu art. 107 ust. 1 Traktatu o funkcjonowaniu Unii Europejskiej1. Jednocześnie praca ta stanowi glosę do obecnie najnowszej wypowiedzi TSUE w tym przedmiocie, czyli do wyroku z dnia 16 marca 2021 r. w sprawie C-562/19 P Komisja Europejska v. Rzeczpospolita Polska2 (podatek od sprzedaży detalicznej), wraz z omówieniem dotychczasowego dorobku orzecznictwa. Artykuł odnosi się do stanu prawa i orzecznictwa na dzień 31 marca 2021 r.