Search results for "TBR"

showing 10 items of 909 documents

The experience of distress during the COVID-19 outbreak: a cross-country examination on the fear of COVID-19 and the sense of loneliness

2020

AbstractObjectivesTo examine gender, age and cross-country differences in fear of COVID-19 and sense of loneliness during the lockdown, by comparing people from countries with a high rate of infections and deaths (i.e. Spain and Italy) and from countries with a mild spread of infection (i.e. Croatia, Serbia, Slovakia, Slovenia, Bosnia and Herzegovina).MethodsA total of 3876 participants (63% female) completed an online survey on “Everyday life practices in COVID-19 time” in April 2020, including measures of fear of COVID-19 and loneliness.ResultsMales and females of all age groups in countries suffering from a strong impact of the COVID-19 pandemic reported higher fear of COVID-19 and sense…

DistressCoronavirus disease 2019 (COVID-19)Economic costPandemicmedicineOutbreakLonelinessmedicine.symptomPsychologyEveryday lifeMental healthDemography
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Cellular Plasticity in the Adult Murine Piriform Cortex: Continuous Maturation of Dormant Precursors Into Excitatory Neurons

2017

Neurogenesis in the healthy adult murine brain is based on proliferation and integration of stem/progenitor cells and is thought to be restricted to 2 neurogenic niches: the subventricular zone and the dentate gyrus. Intriguingly, cells expressing the immature neuronal marker doublecortin (DCX) and the polysialylated-neural cell adhesion molecule reside in layer II of the piriform cortex. Apparently, these cells progressively disappear along the course of ageing, while their fate and function remain unclear. Using DCX-CreERT2/Flox-EGFP transgenic mice, we demonstrate that these immature neurons located in the murine piriform cortex do not vanish in the course of aging, but progressively res…

Doublecortin Domain Proteins0301 basic medicineDoublecortin ProteinCognitive NeuroscienceCell PlasticityGreen Fluorescent ProteinsSubventricular zoneMice TransgenicNerve Tissue ProteinsNeural Cell Adhesion Molecule L1Piriform CortexBiologyMice03 medical and health sciencesCellular and Molecular Neuroscience0302 clinical medicineCortex (anatomy)Piriform cortexNeuroplasticitymedicineAnimalsNeuronsGlutamate DecarboxylaseStem CellsDentate gyrusNeuropeptidesNeurogenesisGene Expression Regulation DevelopmentalEmbryo MammalianCell biologyDoublecortinMice Inbred C57BL030104 developmental biologymedicine.anatomical_structureBromodeoxyuridinenervous systemSialic Acidsbiology.proteinTBR1Calcium-Calmodulin-Dependent Protein Kinase Type 2Microtubule-Associated Proteins030217 neurology & neurosurgeryCerebral Cortex
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Autoimmune hepatitis triggered by COVID-19

2021

We present the case of a 60-year-old woman with no drug allergies or toxic habits, with hypothyroidism and receiving treatment with levothyroxine.

Drugendocrine system2019-20 coronavirus outbreakAllergyendocrine system diseasesCoronavirus disease 2019 (COVID-19)business.industrymedia_common.quotation_subjectSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)GastroenterologyMEDLINELevothyroxineGeneral MedicineAutoimmune hepatitismedicine.diseaseImmunologymedicinebusinesshormones hormone substitutes and hormone antagonistsmedia_commonmedicine.drugRevista Española de Enfermedades Digestivas
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Likkumi Widsemmes semneekeem dohti [Likumi Vidzemes zemniekiem doti]

1820

Bibliogrāfiskās ziņas: Seniespiedumi latviešu valodā, 1525-1855 : kopkatalogs. Rīga : Latvijas Nacionālā bibliotēka, 1999, Nr. 1041. Pieejams tiešsaistē: seniespiedumi_latviesu_valoda_1525_1855.pdf

Dzimtcilvēki. Atbrīvošana. LatvijaLikumdošanas institūcijas. Krievija. Vidzemes guberņa:LAW/JURISPRUDENCE [Research Subject Categories]Vidzemes guberņa (Krievija). Politika un pārvalde
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Eiropas Cilvēktiesību un pamatbrīvību aizsardzības konvencijas 16. protokols: mērķi, saturs, nozīme

2016

Eiropas Cilvēktiesību un pamatbrīvību aizsardzības konvencijas (turpmāk - Konvencija) 16.protokols ir daļa no pasākumiem, kas tiek veikti Konvencijas ilgtermiņa reformu kontekstā. Ar to paplašina Eiropas Cilvēktiesību tiesas (turpmāk – ECT) rekomendējošo jurisdikciju un ievieš jaunu mehānismu Konvencijas cilvēktiesību aizsardzības sistēmā, atbilstoši kuram šī protokola dalībvalstu pēdējo instanču tiesas un tribunāli varēs lūgt ECT sniegt rekomendējošu viedokli. Darbā autors atklāj Konvencijas 16.protokola mērķus, analizē un pēta protokola saturu. Tiek secināts, ka regulējums kaut gan nepilnīgs, ir apmierinošs. Darbā arī tiek izvērtēta protoko…

ECKEiropas Cilvēktiesību un pamatbrīvību aizsardzības konvencijas 16.protokolsKonvencijas reformasECTJuridiskā zinātne
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Early entry events in Echovirus 30 infection

2020

Echovirus 30 (E30), a member of the enterovirus B species, is a major cause of viral meningitis, targeting children and adults alike. While it is a frequently isolated enterovirus and the cause of several outbreaks all over the world, surprisingly little is known regarding its entry and replication strategy within cells. In this study, we used E30 strain Bastianni (E30B) generated from an infectious cDNA clone in order to study early entry events during infection in human RD cells. E30B required the newly discovered Fc echovirus receptor (FcRn) for successful infection, but not the coxsackievirus and adenovirus receptor (CAR) or decay-accelerating factor (DAF), although an interaction with …

EchovirusvirusesReceptors FcVirus Replicationmedicine.disease_causeDisease OutbreaksPhylogenyEnterovirus0303 health sciencesbiologyenterovirusechovirusEnterovirus B HumanVirus-Cell InteractionsenteroviruksetCapsidaivokalvotulehdusRNA ViralECHO-viruksetEndosomeImmunologyEchovirus InfectionsCHO CellsCoxsackievirusMicrobiologyClathrininfektiotVirusCell Line03 medical and health sciencesCricetulusVirologyEnterovirus InfectionsViral meningitismedicineAnimalsHumans030304 developmental biologyearly entry030306 microbiologySequence Analysis DNAVirus Internalizationmedicine.diseasebiology.organism_classificationVirologyaseptic meningitisA549 CellsInsect Sciencebiology.proteinEnterovirus
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West Nile virus in Spain: Forecasting the geographical distribution of risky areas with an ecological niche modelling approach.

2021

West Nile virus (WNV), a well-known emerging vector-borne arbovirus with a zoonotic life cycle, represents a threat to both public and animal health. Transmitted by ornithophilic mosquitoes, its transmission is difficult to predict and even more difficult to prevent. The massive and unprecedented number of human cases and equid outbreaks in Spain during 2020 interpellates for new approaches. For the first time, we present an integrate analysis from a niche perspective to provide an insight to the situation of West Nile disease (WND) in Spain. Our modelling approach benefits from the combined use of global occurrence records of outbreaks of WND in equids and of its two alleged main vectors i…

Ecological nicheGeneral VeterinaryGeneral Immunology and MicrobiologybiologyEcologyNicheOutbreakGeneral MedicineMosquito Vectorsbiology.organism_classificationMediterranean Basinlaw.inventionCulexTransmission (mechanics)GeographylawAbundance (ecology)SpainVector (epidemiology)Culex pipiensAnimalsHumansWest Nile virusEcosystemWest Nile FeverTransboundary and emerging diseasesREFERENCES
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Consequences of plant population size and density for plant-pollinator interactions and plant performance

2001

Summary 1  Habitat fragmentation and the resulting decline in the local abundance of plant species can affect biological interactions. We examined the effects of abundance on plant–pollinator interactions by observing the pollinator service and subsequent reproductive output of a mostly outbreeding, but self-compatible, plant, Lychnis viscaria, in experimental populations of different sizes (number of individuals) and densities (distance between individuals). 2  Bumblebees, the main pollinators of L. viscaria, preferred larger populations, but visitation rates were higher in sparser populations. Pollinators were attracted to the larger inflorescences in sparse populations, which were also m…

EcologyPollinationReproductive successEcologyOutbreeding depressionmedia_common.quotation_subjectPopulation sizefungifood and beveragesPlant ScienceBiologybiology.organism_classificationCompetition (biology)LychnisPollinatorAbundance (ecology)Ecology Evolution Behavior and Systematicsmedia_commonJournal of Ecology
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An ethical algorithm for rationing life sustaining treatment during the COVID-19 pandemic

2020

The burning ethical question raised by the COVID-19 pandemic is how to deal fairly and ethically with a large number of patients simultaneously becoming critically unwell. Across the world, in both developed and developing countries, health systems are grappling with the possibility or the reality that the demand for intensive medical care will outstrip availability. There is a need for ethical guidelines on how to allocate treatment, but such guidelines are potentially highly controversial.1 In this commentary, we set out a simple algorithm (Figure 1), including what we take to be the essential ethical principles that ought to guide resource allocation in any country or setting as well as …

Economic growth2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)utilitarianismPneumonia Viralresource allocationPersonal autonomyArticledecision makingSettore MED/02 - Storia Della MedicinaBetacoronavirusQuality of life (healthcare)Life sustaining treatmentSettore MED/43 - Medicina LegalePandemicHumansMedicinePandemicsSARS-CoV-2business.industryRationingCOVID-19ethicsTriageAnesthesiology and Pain MedicinePersonal AutonomyQuality of LifeethicprognosisCoronavirus InfectionsbusinesstriageAlgorithmsprognosi
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Toward ‘Vaccine Internationalism’: The Need for an Equitable and Coordinated Global Vaccination Approach to Effectively Combat COVID-19

2021

International audience

Economic growth2019-20 coronavirus outbreakHealth (social science)Coronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)global healthequity[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseasesPolitical scienceGlobal healthComputingMilieux_MISCELLANEOUS[SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseasesInternationalism (politics)Public Health Environmental and Occupational HealthEquity (finance)COVID-19vaccinationGlobal governancevaccine policyVaccinationglobal governanceSociety Journal ArchiveCommentary[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologiePublic aspects of medicineRA1-1270[SDV.IMM.VAC]Life Sciences [q-bio]/Immunology/Vaccinologyvaccine distributionpolicyInternational Journal of Public Health
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