Search results for "THC"

Variables that Modulate Home Care Effectiveness in Patients with Chronic Cardiovascular Disease

2019

Introduction: The growing population of patients with chronic cardiovascular disease has many complex biomedical and psychosocial needs and requires an integrated teamwork approach. There is a need to develop a model for assessing the effectiveness of home care in patients with chronic cardiovascular disease, which would take the needs of informal caregivers into account.The purpose of the study was to determine the variables affecting the level of effectiveness of home care, defined as the co-occurrence of high: quality of life (QoL), health behaviours and met needs.Subjects and method: The study involved 193 patients under the care of district nurses and 161 informal caregivers. The study…

Prescription drug use during pregnancy in France: a study from the national health insurance permanent sample.

2017

International audience; PurposeTo provide an up-to-date account of drug prescription during pregnancy in France from 2011 to 2014 using the permanent sample of the French national computerized healthcare database and with a focus on recommended supplementations, fetotoxic drugs and teratogenic drugs.MethodsAll pregnancies identified by the International Classification of Diseases, 10th Revision codes list in the hospitalization database, lasting more than 9 weeks of amenorrhea and whose delivery occurred between 01/01/2011 and 12/31/2014, were included. Drugs delivered between the trimester before and until the end of the pregnancy were included. Drug exposure prevalence was calculated for …

Safety of the current drug treatments for vitiligo

2020

Introduction: Vitiligo is an acquired depigmenting skin disorder adversely affecting the patient's quality of life. Despite the presence of several treatment modalities, ranging from medical to physical to surgical options, none is curative. Each modality has its own drawbacks and side effects. Thus, the treatment modality needs to be tailored for each individual patient taking into consideration the disease characteristics and also its efficacy and safety to obtain a favorable risk-benefit ratio.Areas covered: This review highlights the different treatment modalities utilized in vitiligo up until 4 November 2019 along with their adverse effects and contraindications, if any.Expert opinion:…

Advances in the analysis of legal and illegal drugs in the aquatic environment

2013

We review the current methods developed for the analysis of legal and illegal drugs (LIDs) and their metabolites in environmental samples. We discuss the advantages and the pitfalls of multi-class methods with emphasis on new strategies for sample preparation and recent technical developments. Finally, we present the applicability of these methods to the analysis of LIDs in protected environmental areas.

Long-Term Ventilation in Neuromuscular Patients: Review of Concerns, Beliefs, and Ethical Dilemmas

2019

<b><i>Background:</i></b> Noninvasive mechanical ventilation (NIV) is an effective treatment in patients with neuromuscular diseases (NMD) to improve symptoms, quality of life, and survival. <b><i>Summary:</i></b> NIV should be used early in the course of respiratory muscle involvement in NMD patients and its requirements may increase over time. Therefore, training on technical equipment at home and advice on problem solving are warranted. Remote monitoring of ventilator parameters using built-in ventilator software is recommended. Telemedicine may be helpful in reducing hospital admissions. Anticipatory planning and palliative care should be …

Overcoming traditional Performance Management in Public Healthcare Institutions: The need for a DPM Approach

Donabedian (1988) was the scientific father of the notion that Performance Measurement (PM) of hospital outputs leads to improved quality of healthcare services, setting the foundations of how hospital quality is still today defined, considered and measured using three different kinds of measures: structure, process and outcome measures. Nonetheless, a growing part of literature during the last two decades has started doubting those favourable outcomes of PM on hospital quality (De Vos, et al., 2009; Nolan & Berwick, 2006; Werner et al., 2008a, 2008b; Werner & Bradlow, 2006; Wright & Hershman, 2014) while other research shows that ineffective PM systems are not just useless but …

SHAPES secure cloud platform for healthcare solutions and services

2020

The SHAPES project is an ambitious endeavour that gathers stakeholders from across Europe to create, deploy and pilot at large-scale a EU-standardised open platform incorporating and integrating a broad range of solutions, including technological, organisational, clinical, educational and societal, to enable the ageing population of Europe to remain healthy, active and productive, as well as to maintain a high quality of life and sense of wellbeing for the longest time possible. Not only each digital solution will be ethical, legal and appropriate for users, but also the results will align with the full and ethically responsible end-to-end exploitation of the new functionalities empowered b…

Corruption and Organised Crime Signalling Indicators for Foreign Investors as Applied to Eastern European Countries

2021

The former communist countries in Central and Eastern Europe and, implicitly, their economies, went through specific and sometimes asymmetric developments since the fall of the “iron curtain” at the end of the 1980s. During those years, they faced many challenges to create a secure and predictable economic environment for individuals and businesses, local or foreign. We propose a framework that considers legal, social, and economic indicators which can be used by foreign investors to make wise and efficient business decisions. Our main purpose is to expand the traditional economic analysis framework and enrich it with new institutional and societal indicators from the social, quality of lif…

Fungi and Bacteria in Indoor Cultural Heritage Environments: Microbial-related Risks for Artworks and Human Health

2016

Cultural heritage constitutive materials can provide excellent substrates for microbial colonization, highly influenced by thermo-hygrometric parameters. In cultural heritage-related environments, a detrimental microbial load may be present both on manufacts surface and in the aerosol. In this study, bacterial and fungal colonisation has been investigated in three Sicilian confined environments (archive, cave and hypogea), each with peculiar structures and different thermo-hygrometric parameters. Particular attention has been paid to microorganisms able to induce artifacts biodeterioration and to release biological particles in the aerosol (spores, cellular debrides, toxins and allergens) p…

An ethical algorithm for rationing life sustaining treatment during the COVID-19 pandemic

2020

The burning ethical question raised by the COVID-19 pandemic is how to deal fairly and ethically with a large number of patients simultaneously becoming critically unwell. Across the world, in both developed and developing countries, health systems are grappling with the possibility or the reality that the demand for intensive medical care will outstrip availability. There is a need for ethical guidelines on how to allocate treatment, but such guidelines are potentially highly controversial.1 In this commentary, we set out a simple algorithm (Figure 1), including what we take to be the essential ethical principles that ought to guide resource allocation in any country or setting as well as …