Search results for "Wild"

Adapted conservation measures are required to save the Iberian lynx in a changing climate

2013

The Iberian lynx ( Lynx pardinus ) has suffered severe population declines in the twentieth century and is now on the brink of extinction 1 . Climate change could further threaten the survival of the species 2 , but its forecast effects are being neglected in recovery plans 3,4 . Quantitative estimates of extinction risk under climate change have so far mostly relied on inferences from correlative projections of species’ habitat shifts 5 . Here we use ecological niche models coupled to metapopulation simulations with source–sink dynamics 6,7 to directly investi- gate the combined effects of climate change, prey availabil- ity and management intervention on the persistence of the Iberian lyn…

Record of a 10-year old European Wildcat Felis silvestris silvestris Schreber, 1777 (Mammalia: Carnivora: Felidae) from Mt. Etna, Sicily, Italy

2020

Longevity data for wild felids are lacking in the literature.  Here we report a camera trap recapture of a European Wildcat Felis silvestris at Mt. Etna in Sicily, Italy after nine years.  This individual was clearly identifiable as its tail ended with a white ring rather than the typical black ring and had a unique shape of the dorsal stripe.  At first capture on 26 May 2009, this cat was assessed as an adult, so that the likely minimum age of this individual at the time of recapture on 10 June 2018 must have been be at least 10 years.  This finding represents the oldest known European Wildcat in the wild and provides insight into age structure in wildcat populations.

Are sacred caves still safe havens for the endemic bats of Madagascar?

2018

AbstractDespite conservation discourses in Madagascar increasingly emphasizing the role of customary institutions for wildlife management, we know relatively little about their effectiveness. Here, we used semi-structured interviews with 54 adults in eight villages to investigate whether sacred caves and taboos offer conservation benefits for cave-dwelling bats in and around Tsimanampetsotsa National Park, south-west Madagascar. Although some caves were described as sites of spiritual significance for the local communities, most interviewees (c. 76%) did not recognize their present-day sacred status. Similarly, only 22% of the interviewees recognized taboos inhibiting bat hunting and consum…

Trophic level modulates carabid beetle responses to habitat and landscape structure: a pan-European study

2010

1. Anthropogenic pressures have produced heterogeneous landscapes expected to influence diversity differently across trophic levels and spatial scales. 2. We tested how activity density and species richness of carabid trophic groups responded to local habitat and landscape structure (forest percentage cover and habitat richness) in 48 landscape parcels (1 km2) across eight European countries. 3. Local habitat affected activity density, but not species richness, of both trophic groups. Activity densities were greater in rotational cropping compared with other habitats; phytophage densities were also greater in grassland than forest habitats. 4. Controlling for country and habitat effects we …

Abiotic Stress Tolerance of Coastal Accessions of a Promising Forage Species, Trifolium fragiferum

2021

Crop wild relatives are valuable as a genetic resource to develop new crop cultivars, better adapted to increasing environmental heterogeneity and being able to give high quality yields in a changing climate. The aim of the study was to evaluate the tolerance of different accessions of a crop wild relative, Trifolium fragiferum L., from coastal habitats of the Baltic Sea to three abiotic factors (increased soil moisture, trampling, cutting) in controlled conditions. Seeds from four accessions of T. fragiferum, collected in the wild, were used for experiments, and cv. ‘Palestine’ was used as a reference genotype. Plants were cultivated in asymbiotic conditions of soil culture. Treatments wer…

Continuous wildlife monitoring using blimps as an aerial platform: a case study observing marine megafauna

2020

ABSTRACT Aerial surveys are a powerful means of collecting ecological data in terrestrial and marine systems that may otherwise be difficult to acquire. Increasingly aerial observations are made with Unmanned Aerial Vehicles (UAVs), such as drones. As this technology has improved in reliability and affordability it has replaced the traditional use of fixed-wing aircraft and helicopters. Drones do, however, have limitations; primarily in their limited flight duration, potential to disturb wildlife and concerns over safety. Here we introduce an aerostat, a ground tethered blimp, as a logistically simple and economical alternative to drones and other aircraft. Blimps differ from drones by usin…

2019

Integral membrane proteins of the aquaporin family facilitate rapid water flux across cellular membranes in all domains of life. Although the water-conducting pore is clearly defined in an aquaporin monomer, all aquaporins assemble into stable tetramers. In order to investigate the role of protomer–protomer interactions, we analyzed the activity of heterotetramers containing increasing fractions of mutated monomers, which have an impaired oligomerization propensity and activity. In order to enforce interaction between the protomers, we designed and analyzed a genetically fused homotetramer of GlpF, the aquaglyceroporin of the bacterium Escherichia coli (E. coli). However, increasing fractio…

Overexpression of glucose 6 phosphate dehydrogenase preserves mouse pancreatic beta cells function until late in life.

2021

NAD(P)H donates electrons for reductive biosynthesis and antioxidant defense across all forms of life. Glucose-6- phosphate dehydrogenase (G6PD) is a critical enzyme to provide NADPH. G6PD deficiency is present in more than 400 million people worldwide. This enzymopathy provides protection against malaria but sensitizes cells to oxidative stressors. Oxidative stress has been involved in the pathogenesis of the diabetic complications and several studies have provided evidences of a link between G6PD deficiency and type 2 diabetes (T2D). We hypothesized that a moderate overexpression of G6PD (G6PD-Tg) could protect β-cells from age-associated oxidative stress thus reducing the risk of develop…

14-3-3 Proteins regulate K2P5.1 surface expression on T lymphocytes

2016

K2P5.1 channels (also called TASK-2 or KCNK5) have already been shown to be relevant in the pathophysiology of autoimmune disease since they are known to be upregulated on peripheral and central T lymphocytes of multiple sclerosis (MS) patients. Moreover, overexpression of K2P5.1 channels in vitro provokes enhanced T-cell effector functions. However, the molecular mechanisms regulating intracellular K2P5.1 channel trafficking are unknown so far. Thus, the aim of the study is to elucidate the trafficking of K2P5.1 channels on T lymphocytes. Using mass spectrometry analysis, we have identified 14-3-3 proteins as novel binding partners of K2P5.1 channels. We show that a non-classical 14-3-3 co…

HDAC1 and HDAC2 integrate the expression of p53 mutants in pancreatic cancer.

2015

Mutation of p53 is a frequent genetic lesion in pancreatic cancer being an unmet clinical challenge. Mutants of p53 have lost the tumour-suppressive functions of wild type p53. In addition, p53 mutants exert tumour-promoting functions, qualifying them as important therapeutic targets. Here, we show that the class I histone deacetylases HDAC1 and HDAC2 contribute to maintain the expression of p53 mutants in human and genetically defined murine pancreatic cancer cells. Our data reveal that the inhibition of these HDACs with small molecule HDAC inhibitors (HDACi), as well as the specific genetic elimination of HDAC1 and HDAC2, reduce the expression of mutant p53 mRNA and protein levels. We fur…