Search results for "abilities"
showing 10 items of 538 documents
Multimessenger search for sources of gravitational waves and high-energy neutrinos: Initial results for LIGO-Virgo and IceCube
2014
Made available in DSpace on 2022-04-29T07:21:49Z (GMT). No. of bitstreams: 0 Previous issue date: 2014-11-17 We report the results of a multimessenger search for coincident signals from the LIGO and Virgo gravitational-wave observatories and the partially completed IceCube high-energy neutrino detector, including periods of joint operation between 2007-2010. These include parts of the 2005-2007 run and the 2009-2010 run for LIGO-Virgo, and IceCube's observation periods with 22, 59 and 79 strings. We find no significant coincident events, and use the search results to derive upper limits on the rate of joint sources for a range of source emission parameters. For the optimistic assumption of …
Instability of relativistic sheared jets and distinction between FRI and FRII sources
2002
We investigate the shear-driven instability of nonmagnetic relativistic jets with the bulk velocity, V , dependent on the cylindric radius, r. It is shown that instability can arise for any dependence of the velocity (or the Lorentz factor that is the same) on r. The shear-driven instability can e ectively operate in the whole volume of a jet. The growth time can be shorter than that of the Kelvin-Helmholtz instability. The considered instability leads to a turbulization of jets and can account for a distiction between the jets in the FRI and FRII sources. Urpin, V., Vadim.Urpin@uv.es
How to form a millisecond magnetar? Magnetic field amplification in protoneutron stars
2017
Extremely strong magnetic fields of the order of $10^{15}\,{\rm G}$ are required to explain the properties of magnetars, the most magnetic neutron stars. Such a strong magnetic field is expected to play an important role for the dynamics of core-collapse supernovae, and in the presence of rapid rotation may power superluminous supernovae and hypernovae associated to long gamma-ray bursts. The origin of these strong magnetic fields remains, however, obscure and most likely requires an amplification over many orders of magnitude in the protoneutron star. One of the most promising agents is the magnetorotational instability (MRI), which can in principle amplify exponentially fast a weak initia…
The Hamburg/ESO R-process Enhanced Star survey (HERES):XI. The highly r-process-enhanced star CS 29497-004
2017
We report an abundance analysis for the highly r-process-enhanced (r-II) star CS 29497-004, a very metal-poor giant with Teff = 5013K and [Fe/H]=-2.85, whose nature was initially discovered in the course of the HERES project. Our analysis is based on high signal-to-noise, high-resolution (R~75000) VLT/UVES spectra and MARCS model atmospheres under the assumption of local thermodynamic equilibrium, and obtains abundance measurements for a total of 46 elements, 31 of which are neutron-capture elements. As is the case for the other 25 r-II stars currently known, the heavy-element abundance pattern of CS 29497-004 well-matches a scaled Solar System second peak r-process-element abundance patter…
Part-time special education predicts students' reading self-concept development
2018
Abstract The academic self-concept changes from childhood to early adulthood in relation to experiences of capability in different school tasks and comparison with peers. Students in special education have a lower academic self-concept than their peers do, but it is unclear how part-time special education affects self-concept development. In Finnish schools, part-time special education is learning support that is usually provided for 1–2 h/week in small groups. The main aim of this study was exploring the effects of participation in part-time special education and gender on the level and change in three academic self-concept domains (General School, Mathematics and Reading) between the ages…
Local simulations of the magnetized Kelvin-Helmholtz instability in neutron-star mergers
2010
Context. Global MHD simulations show Kelvin-Helmholtz (KH) instabilities at the contact surface of two merging neutron stars. That region has been identified as the site of efficient amplification of magnetic fields. However, these global simulations, due to numerical limitations, were unable to determine the saturation level of the field strength, and thus the possible back-reaction of the magnetic field onto the flow. Aims. We investigate the amplification of initially weak fields in KH unstable shear flows, and the back-reaction of the field onto the flow. Methods. We use a high-resolution ideal MHD code to perform 2D and 3D local simulations of shear flows. Results. In 2D, the magnetic …
Variant recurrence in neurodevelopmental disorders: the use of publicly available genomic data identifies clinically relevant pathogenic missense var…
2019
Next-generation sequencing has revealed the major impact of de novo variants (DNVs) in developmental disorders (DD) such as intellectual disability, autism, and epilepsy. However, a substantial fraction of these predicted pathogenic DNVs remains challenging to distinguish from background DNVs, notably the missense variants acting via nonhaploinsufficient mechanisms on specific amino acid residues. We hypothesized that the detection of the same missense variation in at least two unrelated individuals presenting with a similar phenotype could be a powerful approach to reveal novel pathogenic variants. We looked for variations independently present in both our database of >1200 solo exomes and…
Heterozygous HMGB1 loss-of-function variants are associated with developmental delay and microcephaly
2021
International audience; 13q12.3 microdeletion syndrome is a rare cause of syndromic intellectual disability. Identification and genetic characterization of patients with 13q12.3 microdeletion syndrome continues to expand the phenotypic spectrum associated with it. Previous studies identified four genes within the approximately 300 Kb minimal critical region including two candidate protein coding genes: KATNAL1 and HMGB1. To date, no patients carrying a sequence-level variant or a single gene deletion in HMGB1 or KATNAL1 have been described. Here we report six patients with loss-of-function variants involving HMGB1 and who had phenotypic features similar to the previously described 13q12.3 m…
Microsomal triglyceride transfer protein gene mutations in Turkish children: A novel mutation and clinical follow up.
2016
Abetalipoproteinemia (ABL; OMIM 200100) is a rare autosomal recessive disease that affects the absorption of dietary fats and fat soluble vitamins. Here, we describe the clinical and genetic characteristics of three patients with ABL. Two patients (patients 1 and 2) who were carriers of the c.398-399delAA mutation (previously known mutation) had developmental delay and hepatic steatosis developed at the age of five in patient 1. Patient 3 was the carrier of a novel mutation (g.10886-10902delAAGgtaagtttgtgttg in intron 3 and c.506A>T exon 5) in microsomal triglyceride transfer protein (MTP) gene and had hepatic steatosis.
A new family with an SLC9A6 mutation expanding the phenotypic spectrum of Christianson syndrome
2016
Using targeted next generation sequencing, we have identified a splicing mutation (c.526-9_526-5del) in the SLC9A6 gene in a 9-year-old boy with mild intellectual disability (ID), microcephaly, and social interaction disabilities. This intronic microdeletion leads to the skipping of exon 3 and to an in-frame deletion of 26 amino acids in the TM4 domain. It segregates with cognitive impairment or learning difficulties in other members of the family. Mutations in SLC9A6 have been reported in X-linked Christianson syndrome associating severe to profound intellectual deficiency and an Angelman-like phenotype with microcephaly, absent speech, ataxia with progressive cerebellar atrophy, ophthalmo…