Search results for "alternative"
showing 10 items of 1466 documents
„JESTEŚ TYM, CO JESZ” : o potędze „czystej” diety
2022
W artykule opisana została jedna z bardziej popularnych obecnie diet, określana mianem prozdrowotnej, tak zwana czysta dieta. Polega ona na eliminacji dostarczania organizmowi między innymi żywności przetworzonej, którą uznaje się za nieczystą, a tym samym szkodliwą i niebezpieczną dla zdrowia człowieka. Obszarem badań objęto blogi i strony internetowe poświęcone temu zagadnieniu, a także wpisy w mediach społecznościowych. W tekście wskazuje się na kulturowe konteksty czystej diety, powody jej popularności, jej powiązanie ze stylem życia i aksjologizowaniem pokarmów oraz na konsekwencje, do jakich stosowanie czystej diety może doprowadzić.
Standardisation of methods for assessing mould germination: a workshop report.
2006
International audience; The first workshop on predictive mycology was held in Marseille, France, 2–4 February 2005 under the auspices of the French Microbiological Society. The purpose of the workshop was to list the different techniques and definitions used by scientists for assessing mould germination and to evaluate the influence of the different techniques on the experimental results. Recommendations were made when a large consensus was obtained. In order to facilitate the study of germination, alternative methods to microscopic examination were examined.
Sense and Antisense DMPK RNA Foci Accumulate in DM1 Tissues during Development.
2015
International audience; Myotonic dystrophy type 1 (DM1) is caused by an unstable expanded CTG repeat located within the DMPK gene 3'UTR. The nature, severity and age at onset of DM1 symptoms are very variable in patients. Different forms of the disease are described, among which the congenital form (CDM) is the most severe. Molecular mechanisms of DM1 are well characterized for the adult form and involve accumulation of mutant DMPK RNA forming foci in the nucleus. These RNA foci sequester proteins from the MBNL family and deregulate CELF proteins. These proteins are involved in many cellular mechanisms such as alternative splicing, transcriptional, translational and post-translational regul…
Muscleblind, BSF and TBPH are mislocalized in the muscle sarcomere of a Drosophila myotonic dystrophy model
2012
SummaryMyotonic dystrophy type 1 (DM1) is a genetic disease caused by the pathological expansion of a CTG trinucleotide repeat in the 3' UTR of the DMPK gene. In the DMPK transcripts, the CUG expansions sequester RNA-binding proteins into nuclear foci, including transcription factors and alternative splicing regulators such as MBNL1. MBNL1 sequestration has been associated with key features of DM1. However, the basis behind a number of molecular and histological alterations in DM1 remain unclear. To help identify new pathogenic components of the disease, we carried out a genetic screen using a Drosophila model of DM1 that expresses 480 interrupted CTG repeats, i(CTG)480, and a collection of…
Molecular Effects of the CTG Repeats in Mutant Dystrophia Myotonica Protein Kinase Gene
2008
Myotonic Dystrophy type 1 (DM1) is a multi-system disorder characterized by muscle wasting, myotonia, cardiac conduction defects, cataracts, and neuropsychological dysfunction. DM1 is caused by expansion of a CTG repeat in the 3 untranslated region (UTR) of the Dystrophia Myotonica Protein Kinase (DMPK) gene. A body of work demonstrates that DMPK mRNAs containing abnormally expanded CUG repeats are toxic to several cell types. A core mechanism underlying symptoms of DM1 is that mutant DMPK RNA interferes with the developmentally regulated alternative splicing of defined pre-mRNAs. Expanded CUG repeats fold into ds(CUG) hairpins that sequester nuclear proteins including human Muscleblind-lik…
Acupuncture in the treatment of temporomandibular disorders, facial pain, and postural neuromuscular disorders. Presentation of a clinical case
2021
Abstract Background and objectives Temporomandibular disorders have a multifactorial etiology and involve the masticatory muscles, temporomandibular joint and associated structures. Therefore, different treatments are proposed and used. The aim of this paper is the use of acupuncture to treat temporomandibular disorders and associated symptoms. This article presents a clinical case study of a 39-year-old patient who presented temporomandibular disorders and headache of muscular origin. Results After 10 acupuncture sessions, the results were highly satisfactory, with complete relief of headache pain and absence of joint disorders. These results suggest the efficacy of acupuncture in the symp…
Rhythmic exercises as tools for rehabilitation following cerebellar stroke: A case study integrating music therapy and physiotherapy techniques
2022
Introduction: This article explores the use of music and multisensory stimuli in the construction of compensatory neural networks for motoric functioning in a patient recovering from cerebellar strokes (CS). This study aimed to address the real-world clinical concern of patients having a passive role in therapy, by arousing the client’s interest and self-motivation in rehabilitation. Method: The article presents a case study of a CS survivor, using data derived from rehabilitation sessions combining music therapy techniques with physiotherapy techniques to improve the fluency and accuracy of his motor performance. Qualitative and quantitative data are used to identify, describe, and evaluat…
La combustione HCCI mediante miscele di gas naturale e benzina: una prima esperienza sperimentale
2016
Si presentano in questo articolo i risultati di una sperimentazione volta a valutare la possibilità di effettuare una combustione HCCI (Homogeneous Charge Compression Ignition) stabile mediante l’impiego di miscele di gas naturale (GN) e benzina. La combustione HCCI ha ottime prerogative di basso impatto ambientale, ma la sua realizzazione pone qualche problema di stabilità al variare delle condizioni di carico richieste al motore: lo studio condotto mostra come l’impiego di miscele di GN e benzina, la cui composizione permette di variarne la resistenza all’autoaccensione, consente di ampliare il campo di funzionamento stabile della combustione HCCI. In the last decade the HCCI combustion h…
Drug Induced Liver Injury (DILI) due to variability in monacolin K content in Red Yeast Rice (RYR): An expert opinion
2020
Abstract Introduction Red yeast rice (RYR) is an effective cholesterol-lowering nutraceutical reversibly inhibiting 3-hydroxy-3-methyl-glutaryl-CoA (HMG-CoA) reductase. As liver damage is a possible (albeit rare) side effect of HMG-CoA inhibitors, it make sense to focus on the tolerability of the liver to RYR extracts. The aim of this paper is to offer an expert opinion on the risk of liver damage by the use of RYR extract. Methods A review of the available literature has been carried out and critically reviewed by the authors. Results According to a large meta-analysis of 53 randomized clinical trials comprising 112 treatment arms, which included 8535 subjects with 4437 in the RYR arm and …
Effect of Germacrene-Rich Essential Oil of Parentucellia latifolia (L.) Caruel Collected in Central Sicily on the Growth of Microorganisms Inhabiting…
2022
In the present study, the chemical composition of the essential oil from aerial parts of Parentucellia latifolia (L.) Caruel collected in Central Sicily was analyzed by gas chromatography and gas chromatography–mass spectrometry. The results showed the presence of sesquiterpene hydrocarbons, with germacrene D and germacrene B accounting, respectively, for 59.2% and 24.3% of the total oil. Different colonies of bacteria and fungi frequently affect cellulosic objects such as books stored in libraries and museums. The antibacterial and antifungal activity against some microorganisms infesting historical-artistic craftsmanship was determined, demonstrating that the essential oil was particular…