Search results for "antimicrobia"
showing 10 items of 715 documents
Obtaining and research of callus mass of Gentiana lutea L roots
2015
The results of introduction to the culture in vitro Gentiana lutea L. are provided. The influence of phytohormones on growth processes of plant cells is researched, the optimal conditions for cultivation of Gentiana lutea L. are defined and chosen. Biomass extract is obtained and is researched on the presence in it the biologically active substances and antimicrobial activity.
Toward Sustainable PLA-Based Multilayer Complexes with Improved Barrier Properties
2019
Poly(lactic acid) or PLA is currently considered as one of the most promising substitutes of conventional plastics, with low environmental impact, especially for food packaging applications. Nevertheless, some drawbacks, such as high permeability to oxygen, are still limiting its industrial applications. The objective of this study was to highly increase the oxygen barrier performance of PLA without compromising its sustainable nature and following the principles of circular economy perspective. Coproducts coming from mill industries, such as wheat gluten proteins (WG), were used to produce PLA-WG-PLA multilayer complexes with improved barrier performance. Different technologies of industri…
Efficacy and safety of photodynamic therapy with RLP068 for diabetic foot ulcers: a review of the literature and clinical experience
2020
This article is the second part of a literature review concerning diabetic foot ulcers (DFUs) and the use of antimicrobial photodynamic therapy (PDT). PDT involves the topical application of a photosensitiser into the tissue, followed by illumination that induces the formation of reactive oxygen species (ROS). PDT provides bacterial inactivation and promotes wound healing, and it can be used to manage the infection and microbial colonisation of DFUs. It has pivotal advantages in comparison with chemotherapeutics, such as no potential to induce resistance, and a wide spectrum of activity. Tetracationic Zn(II) phthalocyanine derivatives have been developed for PDT. Among these, we would like …
Cyano-Phycocyanin: Mechanisms of Action on Human Skin and Future Perspectives in Medicine
2022
Cyano-phycocyanin is one of the active pigments of the blue-green algae and is usually isolated from the filamentous cyanobacteria Arthrospira platensis Gomont (Spirulina). Due to its multiple physiological functions and non-toxicity, cyano-phycocyanin may be a potential substance for the topical treatment of various skin diseases. Considering that the conventional medicine faces drug resistance, insufficient efficacy and side effects, the plant origin compounds can act as an alternative option. Thus, the aim of this paper was to review the wound healing, antimicrobial, antioxidative, anti-inflammatory, antimelanogenic and anticancer properties and mechanisms of cyano-phycocyanin topical ac…
Bacterial biofilms: a challenge in the discovery of new anti-infective agents.
2010
The ability to form a biofilm, bacterial communities able to grow on surfaces and surrounded by an extracellular polymeric substance biofilm agents.Our research group focused on discovering of novel chemical agents of potential therapeutic utility in the treatment of staphylococcal biofilm-associatedinfections by screening novel compounds (synthetic or natural). In a recent study, the antistaphylococcalbiofilm activity of pyrrolomycins C,D, F1, F2a, F2b, F3 a family of halogenated pyrroles which are naturally produced byActinosporangium vitaminophylum and of the synthesized related compounds I, II, III were investigated and compared (Schillaci et al, 2010). We also focused on marine inverte…
Optical quality of hyperopic and myopic phakic intraocular lenses
2013
Aims: To assess and compare the optical quality of the myopic and hyperopic implantable collamer lens (ICL) from its wavefront aberrations for different powers and pupil diameters. Settings and Design: Prospective study. Material and Methods: The wavefront aberrations of two myopic (−3 and −6 diopters (D)) and two hyperopic V4b ICLs (+3 and +6D) were measured in vitro . To assess and compare the optical quality of different powers of ICLs, we analyzed the root mean square (RMS) of total higher order aberrations (HOAs), trefoil, coma, tetrafoil, secondary astigmatism, and spherical aberration at 3- and 4.5-mm pupil. In addition, the point spread functions (PSFs) of each ICL evaluated were ca…
Chemical composition of the essential oil of Elaeoselinum asclepium (L.) Bertol subsp. meoides (Desf.) Fiori (Umbelliferae) collected wild in Central…
2020
In the present study, the chemical composition of the essential oils from flowers and leaves of Elaeoselinum asclepium(L.) Bertol subsp. meoides(Desf.) Fiori collected in Central Sicily was evaluated by GC and GC-MS. The main volatile components of the flowers were alpha-phellandrene (42.5%), terpinolene (15.7%), p-cymene (11.6%) and beta-phellandrene (10.2%), whereas the ones of the leaves were p-cymene (44.0%), alpha-pinene (13.2%), alpha-phellandrene (11.0%), beta-phellandrene (10.2%) and beta-pinene (9.2%). Furthermore, the antibacterial and antifungal activities against some microorganisms infesting historical art craft were determined. The essential oil from leaves (EL) showed to be p…
Immunolocalization of an antimicrobial peptide in Ciona intestinalis (Tunicata ) tunic
2009
The effect of carvacrol on enteric viruses.
2014
Carvacrol, a monoterpenic phenol, is said to have extensive antimicrobial activity in a wide range of food spoilage or pathogenic fungi, yeast and bacteria. The aim of this study was to assess its antiviral activity on norovirus surrogates, feline calicivirus (FCV), murine norovirus (MNV), and hepatitis A virus (HAV), as well as its potential in food applications. Initially, different concentrations of carvacrol (0.25, 0.5, 1%) were individually mixed with each virus at titers of ca. 6-7 log TCID50/ml and incubated 2h at 37°C. Carvacrol at 0.5% completely inactivated the two norovirus surrogates, whereas 1% concentration was required to achieve ca. 1 log reduction of HAV. In lettuce wash wa…
Doslidžennâ bìologìčnoï aktivnostìvtorinnogo ekstraktu zì šrotu travimaterinki zvičajnoï (Origanum vulgare)
2015
Studied the antimicrobial activity of secondary extract from oregano herbs waste (Origanum vulgare)against 7 standard test strains of microrganisms. Minimum bactericidal concentration of the extract to Staphylococcus aureus ATCC 6538 P-is 3.125-6.25 mg/ml and 6.25-12.5 mg/ml to gram-negative bacteria and Candida albicans ATCC 10231.Total antioxidant activity determined by DPPH, secondary extract at a concentration of 400 ug/ml was 92 %. The tested extract had photoprotective activity. Obtained results confirm the perspective of using waste of oregano herbs for making extracts and creation on their basis of pharmaceuticals, veterinary drugs and cosmetics.