Search results for "clinica"
showing 10 items of 38311 documents
Toward modernizing the systematic review pipeline in genetics: efficient updating via data mining
2012
Purpose: The aim of this study was to demonstrate that modern data mining tools can be used as one step in reducing the labor necessary to produce and maintain systematic reviews. Methods: We used four continuously updated, manually curated resources that summarize MEDLINE-indexed articles in entire fields using systematic review methods (PDGene, AlzGene, and SzGene for genetic determinants of Parkinson disease, Alzheimer disease, and schizophrenia, respectively; and the Tufts Cost-Effectiveness Analysis (CEA) Registry for cost-effectiveness analyses). In each data set, we trained a classification model on citations screened up until 2009. We then evaluated the ability of the model to class…
Decompressive Craniectomy Improves QTc Interval in Traumatic Brain Injury Patients
2020
Background: Traumatic brain injury (TBI) is commonly associated with cardiac dysfunction, which may be reflected by abnormal electrocardiograms (ECG) and/or contractility. TBI-related cardiac disorders depend on the type of cerebral injury, the region of brain damage and the severity of the intracranial hypertension. Decompressive craniectomy (DC) is commonly used to reduce intra-cranial hypertension (ICH). Although DC decreases ICH rapidly, its effect on ECG has not been systematically studied. The aim of this study was to analyze the changes in ECG in patients undergoing DC. Methods: Adult patients without previously known cardiac diseases treated for isolated TBI with DC were studied. EC…
Text Linguistics and Classical Studies: Dressler and de Beaugrande’s Procedural Approach
2017
The work represents a significant scientific advancement on text linguistics from three different viewpoints. The first chapter provides an overview of the history of text linguistics from a broader perspective than usual, offering a complete reference framework. The second chapter presents the procedural approach to the study of text linguistics in a concise way, including a critical comparison with other perspectives. The third chapter constructs a very unusual bridge between theoretical linguistics and classical studies in that it takes a literary text in Latin from the early imperial period as its case study. This combination is rare, as theoretical linguists are usually oriented to mod…
Drivers’ experiences during floods: Investigating the psychological influences underpinning decisions to avoid driving through floodwater
2018
Abstract A major risk factor for many flood-related drownings is driving through floodwater. We aimed to understand Australian drivers’ experiences and beliefs with respect to avoid driving through floodwater using the theory of planned behaviour as a framework. Study 1 (N = 23) used a qualitative design to gain an in-depth understanding of individuals’ experiences with driving through floodwater. Study 2 (N = 157) used a survey-based design to identify the factors related to this behaviour including knowledge, beliefs, and social-cognitive factors. In Study 1, drivers identified a range of advantages (e.g., didn’t damage car), disadvantages (e.g., inconvenient, but not so terrible), barrie…
On the Choice of the Extracellular Vesicles for Therapeutic Purposes
2019
Extracellular vesicles (EVs) are lipid membrane vesicles released by all human cells and are widely recognized to be involved in many cellular processes, both in physiological and pathological conditions. They are mediators of cell-cell communication, at both paracrine and systemic levels, and therefore they are active players in cell differentiation, tissue homeostasis, and organ remodeling. Due to their ability to serve as a cargo for proteins, lipids, and nucleic acids, which often reflects the cellular source, they should be considered the future of the natural nanodelivery of bio-compounds. To date, natural nanovesicles, such as exosomes, have been shown to represent a source of diseas…
Relationship Between Cannabis Use and Erectile Dysfunction: A Systematic Review and Meta-Analysis
2019
Globally, there is increasing usage and legalization of cannabis. In addition to its reported therapeutic effects, cannabis has several health risks which are not clearly defined. Erectile dysfunction (ED) is the most common male sexual disorder and there are plausible mechanisms linking cannabis use to ED. No attempt has been made to collate the literature on this topic. The aim of this review was to summarize the prevalence and risk of ED in cannabis users compared to controls. A systematic review of major databases from inception to January 1, 2019, without language restriction, was undertaken to identify studies investigating cannabis use and presence of ED. The analysis compared the p…
Self-reported reflective functioning mediates the association between attachment insecurity and well-being among psychotherapists.
2020
Objective: Subjective well-being is a crucial variable for mental health practitioners. This study examines the influence of therapists’ attachment dimensions and self-reported reflective functioning on their perceived well-being. Further, it examines if reflective functioning mediates the association between attachment insecurity and well-being. Method: A total of 416 experienced psychotherapists were enrolled in this cross-sectional study, and completed self-report measures of attachment insecurity, reflective functioning, and well-being. We tested the hypothesized mediation model with path analysis that examined indirect effects. Results: Both attachment anxiety and avoidance dimensions …
Displaying agency problems at the outset of psychotherapy
2016
In order to present him- or herself at the outset of psychotherapy as a credible client, the person needs to, on one hand, formulate a sense of lost agency in accounts of his/her life situation, and on the other, to present him- or herself as willing and able to take part in conversational self-exploration. In this study, we looked in detail at how one person, seeking psychotherapy, constructed accounts that served this double function. We sought to develop the usefulness of the concept of agency as an integrative theoretical construct of core processes in therapy and introduced a model of five aspects of agentic vs. non-agentic presentation, developed and applied in an earlier study on cli…
Curso de la asignatura: "Clinical Nutrition or Diet Therapy" (Parte Teoria Pilar Vila Donat)
2021
Este material docente ha sido previamente revisado mediante la ayuda del Servei de Política Lingüística de la Universitat de València Clinical Nutrition or Diet Therapy is a compilation of units that make up half of the Clinical Nutrition subject. Specifically, this subject is intended for Pharmacy degree 3rd year students, who study in English line, so this is an excellent study tool for them, explaining the background to nutritional disorders and enabling nutritional care to be planned. All new terms are defined and the material is comprehensively referenced. This material has been prepared taking as reference the text book entitled: Krause’s Food and The Nutrition Care Process. The mater…
Thrombolysis Followed by Apixaban for Massive Pulmonary Embolism and Free-floating Thrombus in Right Ventricle in a Patient with Breast Cancer
2018
Free-floating thrombus in the right ventricle, associated with a massive acute pulmonary embolism (PE), is a rare phenomenon. PE is an important clinical entity with considerable mortality despite advances in diagnosis and treatment. The prognosis of PE depends on right ventricular dysfunction, myocardial injury markers, and early treatment. In this report, we present the case of a 71-year-old woman with a history of breast cancer admitted to intensive care unit for PE complicated by syncope. Although our case may seem complex because it is not represented in the guidelines, the result was satisfactory and showed how treatment with new anticoagulants (in this case apixaban) after massive th…