Search results for "curs"

Secretion of neutral and acid DNases in cultivated human lymphocytes after incubation with DNA; possible consequences for inhalation anesthesia.

1995

Abstract After incubation with DNA human lymphocytes release neutral and acid DNase activities into the culture medium; the release depends on DNA concentration and time of cultivation. The electrophoretic mobility of the released neutral DNase activity is in accordance with DNase I and the electrophoretic mobility of the released acid DNase activity with DNase II. The released DNase activities do not originate from dead cells and are not influenced by blast cell formation. The anesthetic halothane can inhibit the released neutral and acid DNase activities. Inhalation anesthesia can possibly disturb the correlation between DNA and DNases in human blood.

Insect Immune Evasion by Dauer and Nondauer Entomopathogenic Nematodes

2021

The immune response of animals, including insects, is overcome by some parasites. For example, dauer larvae (DL) of the obligate entomopathogenic nematodes (EPNs) Heterorhabditis and Steinernema can invade insects, evade their defenses, and cause death. Although DL were long assumed to be the only infective stage of nematodes, recent reports suggest that L2-L3 larvae of facultative EPNs are also capable of killing insects. There are no studies, to our knowledge, about the role of nonimmunological barriers (the exoskeleton and its openings) in avoiding infection by DL and L2-L3 larvae, or whether these larval stages evade the host immune system in the same way. The objective of this study wa…

Familiarity and visit characteristics as determinants of tourists' experience at a cruise destination

2019

Abstract The main aim of this study was to examine the differences in the interrelationships between destination image-satisfaction-behavioural intention across cruise tourists with varying visit characteristics (length of stay and type of visit arrangement) and familiarity. The data for the study was obtained through interviews with cruise passengers visiting a major Spanish port of call. The results revealed that both familiarity (informational and behavioural) and type of visit arrangement (excursion versus independent visit) moderated the hypothesized structural relationships. The moderating role of length of stay onshore was only demonstrated on the impact of satisfaction on behavioura…

Propuesta de un método de evaluación del patrimonio cultural y su aplicación en Cortes de Pallás (Valencia)

2020

Las áreas rurales han experimentado significativas transformaciones socioeconómicas en las últimas décadas, en las cuales ha sido común la competencia de los ámbitos urbanos. Actualmente constituyen espacios multifuncionales caracterizados por el desempeño de nuevas actividades, donde el patrimonio se configura como un recurso esencial en las estrategias de desarrollo territorial (local). No obstante, el diseño de proyectos de valorización requiere la identificación del valor de cada bien. El propósito del estudio es la propuesta de un método de evaluación del patrimonio cultural, conformado por tres sistemas específicos que permiten cuantificar el interés patrimonial de los bienes inmueble…

Aproximación al servicio de acogimiento residencial, en la Comunidad Valenciana: Estudio comparado de la situación actual y perspectiva de futuro

2017

A partir del año 2008, como consecuencia de que España entrará en la crisis económica, el número de la infancia situada por debajo del umbral de pobreza, aumento considerablemente, convirtiendo a uno de cada cuatro niños/as en pobre, situando así a España, en el cuarto país con mayor tasa de pobreza infantil (un 27%) de la Unión Europea (Save The Children, 2013). Como determinó González (2008): Los menores en situación de riesgo no son patrimonio de un colectivo concreto, sino más bien de familias con diferentes y múltiples problemáticas o dificultades (falta de recursos materiales, económicos, elevado nivel de estrés familiar, falta de estrategia de resolución de problemas por medios respe…

Trandix: Herramienta Proactiva para la Búsqueda Terminológica del Traductor y su Evaluación

2014

This article is the English version of “Trandix: herramienta proactiva para la búsqueda terminológica del traductor y su evaluación” by Isabel Durán Muñoz & Alejandro Fernández Sola. It was not published on the print version of MonTI for reasons of space. The online version of MonTI does not suffer from these limitations, and this is our way of promoting plurilingualism. This paper analyses current trends in the terminological field and translators’ needs regarding terminological resources. In this context, it presents the Trandix tool, a novel software application that intends to enhance efficiency in terminological searches conducted by translators. In addition to its main features, this …

Traducción de calidad de webs hoteleras: discurso interpersonal e implicación del cliente

2015

espanolEste trabajo sugiere la necesaria traduccion de calidad o traduccion “pragmatica” de paginas web de hotel (Duran Munoz, 2011), segun el principio de localizacion (Pym, 2004; Dunne, 2006) y segun el discurso interpersonal, siguiendo la clasificacion de Hyland y Tse (2004), con objeto de preservar la persuasion del lector/cliente. Para ello se ha analizado un subcorpus de paginas web de hotel que ofrecen traduccion (COMETVAL, Corpus Multilingue en Turismo, Universitat de Valencia), traducidas de ingles a espanol, de hoteles de EEUU y Reino Unido, teniendo en cuenta el patron interpersonal del espanol en generos turisticos (Mapelli, 2008; Suau-Jimenez, 2012a, 2012b). El estudio se contr…

Trandix: herramienta proactiva para la búsqueda terminológica del traductor y su evaluación

2014

This paper analyses current trends in the terminography field and translators’ needs regarding terminology resources. In this context, the Trandix tool is presented as a novel software application that pursues efficiency in terminological searches conducted by translators. This tool is based on Tarp’s Function Theory of Lexicography (2008a) and Spohr’s proposal concerning electronic multifunctional dictionaries (2009). A further goal of this paper is to serve as an example for future research in terminological resources aiming to meet translators’ requirements and expectations when carrying out terminology searches

2004

This paper presents the use of Support Vector Machines (SVMs) for prediction and analysis of antisense oligonucleotide (AO) efficacy. The collected database comprises 315 AO molecules including 68 features each, inducing a problem well-suited to SVMs. The task of feature selection is crucial given the presence of noisy or redundant features, and the well-known problem of the curse of dimensionality. We propose a two-stage strategy to develop an optimal model: (1) feature selection using correlation analysis, mutual information, and SVM-based recursive feature elimination (SVM-RFE), and (2) AO prediction using standard and profiled SVM formulations. A profiled SVM gives different weights to …

Differential Regulation of CCL22 Gene Expression in Murine Dendritic Cells and B Cells

2005

Abstract The activated T cell-attracting CC chemokine CCL22 is expressed by stimulated B cells and mature dendritic cells (DC). We have cloned and sequenced the complete mouse gene, including 4 kb of the 5′-flanking promoter region, and detected two distinct sites for initiation of transcription by 5′-RACE. Reporter gene assays indicate that the promoter reflects the specificity of the endogenous gene. Within the proximal promoter region, we identified potential binding sites for NF-κB, Ikaros, and a putative GC box. All three regions bind proteins. The NF-κB site was shown to specifically bind NF-κB subunits p50 and p65 from nuclear extracts of LPS-stimulated B cells, B cell line A20/2J, T…